Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Dry Eye Syndromes D015352 10 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Hyperpigmentation D017495 11 associated lipids
Myocardial Stunning D017682 10 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Darier Disease D007644 2 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Retinal Degeneration D012162 9 associated lipids
Dermatitis, Toxicodendron D011040 3 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Pellagra D010383 1 associated lipids
Tinea Versicolor D014010 5 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Radunz-Neto J et al. Estimation of essential fatty acid requirements of common carp larvae using semi-purified artificial diets. 1996 Arch Tierernahr pmid:8766972
Aoshima H Potentiation and inhibition of ionotropic neurotransmitter receptors expressed in Xenopus oocyte by linoleic acid and its hydroperoxide. 1996 J. Neurochem. pmid:8769897
Connolly JM et al. Dietary linoleic acid-stimulated human breast cancer cell growth and metastasis in nude mice and their suppression by indomethacin, a cyclooxygenase inhibitor. 1996 Nutr Cancer pmid:8771566
Fellner V et al. Steady-state rates of linoleic acid biohydrogenation by ruminal bacteria in continuous culture. 1995 J. Dairy Sci. pmid:8786265
Murphy MG Effects of exogenous linoleic acid on fatty acid composition, receptor-mediated cAMP formation, and transport functions in rat astrocytes in primary culture. 1995 Neurochem. Res. pmid:8786824
Ain Baziz H et al. Chronic heat exposure enhances fat deposition and modifies muscle and fat partition in broiler carcasses. 1996 Poult. Sci. pmid:8786940
Carnielli VP et al. The very low birth weight premature infant is capable of synthesizing arachidonic and docosahexaenoic acids from linoleic and linolenic acids. 1996 Pediatr. Res. pmid:8798265
Porkkala-Sarataho E et al. Increased oxidation resistance of atherogenic plasma lipoproteins at high vitamin E levels in non-vitamin E supplemented men. 1996 Atherosclerosis pmid:8800496
Yamada Y et al. Production of hydroxy fatty acid (10-hydroxy-12(Z)-octadecenoic acid) by Lactobacillus plantarum from linoleic acid and its cardiac effects to guinea pig papillary muscles. 1996 Biochem. Biophys. Res. Commun. pmid:8806645
Hörnsten L et al. Dexamethasone induces bisallylic hydroxylation of polyunsaturated fatty acids by rat liver microsomes. 1996 Arch. Biochem. Biophys. pmid:8806734
Mizushina Y et al. Fatty acids selectively inhibit eukaryotic DNA polymerase activities in vitro. 1996 Biochim. Biophys. Acta pmid:8809118
Ves-Losada A and Brenner RR Long-chain fatty Acyl-CoA synthetase enzymatic activity in rat liver cell nuclei. 1996 Mol. Cell. Biochem. pmid:8813703
Banni S et al. A novel approach to study linoleic acid autoxidation: importance of simultaneous detection of the substrate and its derivative oxidation products. 1996 Free Radic. Res. pmid:8814443
Kaneko T et al. Cytotoxicity of phosphatidylcholine hydroperoxides is exerted through decomposition of fatty acid hydroperoxide moiety. 1996 Free Radic. Biol. Med. pmid:8818632
Toborek M et al. Linoleic acid and TNF-alpha cross-amplify oxidative injury and dysfunction of endothelial cells. 1996 J. Lipid Res. pmid:8820108
Hatch GM and McClarty G Regulation of cardiolipin biosynthesis in H9c2 cardiac myoblasts by cytidine 5'-triphosphate. 1996 J. Biol. Chem. pmid:8824210
Engberg RM et al. Inclusion of oxidized vegetable oil in broiler diets. Its influence on nutrient balance and on the antioxidative status of broilers. 1996 Poult. Sci. pmid:8829233
Boyd NF et al. Long-term effects of participation in a randomized trial of a low-fat, high-carbohydrate diet. 1996 Cancer Epidemiol. Biomarkers Prev. pmid:8833622
Essien EU et al. Lipid composition of lesser known tropical seeds. 1995 Plant Foods Hum Nutr pmid:8837872
Glickman MH and Klinman JP Lipoxygenase reaction mechanism: demonstration that hydrogen abstraction from substrate precedes dioxygen binding during catalytic turnover. 1996 Biochemistry pmid:8841132
Canudas N et al. Photodegradation of bezafibrate in aqueous media. Studies of its in vitro phototoxicity. 1996 Arzneimittelforschung pmid:8842340
Venuta A et al. Essential fatty acids: the effects of dietary supplementation among children with recurrent respiratory infections. 1996 Jul-Aug J. Int. Med. Res. pmid:8854285
Okaniwa Y et al. A high linoleate and a high alpha-linolenate diet induced changes in learning behavior of rats. Effects of a shift in diets and reversal of training stimuli. 1996 Biol. Pharm. Bull. pmid:8860953
Hudson JA et al. Hydration of oleic acid by a Selenomonas strain from the ovine rumen. 1996 Lett. Appl. Microbiol. pmid:8862016
Schurz HH et al. Products of aniline and triglycerides in oil samples associated with the toxic oil syndrome. 1996 Chem. Res. Toxicol. pmid:8870988
Schingoethe DJ et al. Lactational responses of dairy cows fed unsaturated fat from extruded soybeans or sunflower seeds. 1996 J. Dairy Sci. pmid:8872718
Belury MA et al. Dietary conjugated linoleic acid modulation of phorbol ester skin tumor promotion. 1996 Nutr Cancer pmid:8875552
Godessart N et al. Prostaglandin H-synthase-2 is the main enzyme involved in the biosynthesis of octadecanoids from linoleic acid in human dermal fibroblasts stimulated with interleukin-1beta. 1996 J. Invest. Dermatol. pmid:8875957
Lammoglia MA et al. Effects of dietary fat and season on steroid hormonal profiles before parturition and on hormonal, cholesterol, triglycerides, follicular patterns, and postpartum reproduction in Brahman cows. 1996 J. Anim. Sci. pmid:8880430
Engels F et al. Preferential formation of 13-hydroxylinoleic acid by human peripheral blood eosinophils. 1996 Prostaglandins pmid:8880897
Van Nevel CJ and Demeyer DI Influence of pH on lipolysis and biohydrogenation of soybean oil by rumen contents in vitro. 1996 Reprod. Nutr. Dev. pmid:8881592
Eder K and Kirchgessner M Zinc deficiency and the desaturation of linoleic acid in rats force-fed fat-free diets. 1996 Biol Trace Elem Res pmid:8886317
Peet M et al. Essential fatty acid deficiency in erythrocyte membranes from chronic schizophrenic patients, and the clinical effects of dietary supplementation. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8888126
Langley-Evans SC et al. Influence of dietary fats upon systolic blood pressure in the rat. 1996 Int J Food Sci Nutr pmid:8889627
Luukkainen P et al. Impact of solid food on plasma arachidonic and docosahexaenoic acid status of term infants at 8 months of age. 1996 J. Pediatr. Gastroenterol. Nutr. pmid:8890071
Aksnes J et al. Long term lipid-based parenteral nutrition causes pulmonary hypertension in pigs. 1996 Eur J Surg pmid:8891624
Ito MK and Simpson KL The biosynthesis of omega 3 fatty acids from 18:2 omega 6 in Artemia spp. 1996 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:8896333
Avery SV et al. Copper toxicity towards Saccharomyces cerevisiae: dependence on plasma membrane fatty acid composition. 1996 Appl. Environ. Microbiol. pmid:8899983
Lomascolo A et al. Study of the delta 12-desaturase system of Lipomyces starkeyi. 1996 Lipids pmid:8900454
van den Boom MA et al. The influence of a fish oil-enriched diet on the phospholipid fatty acid turnover in the rabbit red cell membrane in vivo. 1996 Lipids pmid:8900458
Yazu K et al. Mechanism of lower oxidizability of eicosapentaenoate than linoleate in aqueous micelles. 1996 Lipids pmid:8900464
Cunnane SC The Canadian Society for Nutritional Sciences 1995 Young Scientist Award Lecture. Recent studies on the synthesis, beta-oxidation, and deficiency of linoleate and alpha-linolenate: are essential fatty acids more aptly named indispensable or conditionally dispensable fatty acids? 1996 Can. J. Physiol. Pharmacol. pmid:8909772
Cunnane SC and Likhodii SS 13C NMR spectroscopy and gas chromatograph--combustion--isotope ratio mass spectrometry: complementary applications in monitoring the metabolism of 13C-labelled polyunsaturated fatty acids. 1996 Can. J. Physiol. Pharmacol. pmid:8909789
Godley PA et al. Biomarkers of essential fatty acid consumption and risk of prostatic carcinoma. 1996 Cancer Epidemiol. Biomarkers Prev. pmid:8922296
Loidl-Stahlhofen A et al. Gas chromatographic-electron impact mass spectrometric screening procedure for unknown hydroxyaldehydic lipid peroxidation products after pentafluorobenzyloxime derivatization. 1995 J. Chromatogr. B, Biomed. Appl. pmid:8925062
Mensink R Essential and trans-fatty acids. 1996 Curr. Opin. Lipidol. pmid:8925181
Mutanen M and Freese R Polyunsaturated fatty acids and platelet aggregation. 1996 Curr. Opin. Lipidol. pmid:8925182
Sugano M and Ikeda I Metabolic interactions between essential and trans-fatty acids. 1996 Curr. Opin. Lipidol. pmid:8925188
Glaesser D et al. Low concentrations of cis-linoleic acid induce cell damage in epithelial cells from bovine lenses. 1996 Eur. J. Cell Biol. pmid:8929567
Ranganath LR et al. Increased mean platelet volume after oestrogen replacement therapy. 1996 Ann. Clin. Biochem. pmid:8937589