Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Radunz-Neto J et al. | Estimation of essential fatty acid requirements of common carp larvae using semi-purified artificial diets. | 1996 | Arch Tierernahr | pmid:8766972 |
Aoshima H | Potentiation and inhibition of ionotropic neurotransmitter receptors expressed in Xenopus oocyte by linoleic acid and its hydroperoxide. | 1996 | J. Neurochem. | pmid:8769897 |
Connolly JM et al. | Dietary linoleic acid-stimulated human breast cancer cell growth and metastasis in nude mice and their suppression by indomethacin, a cyclooxygenase inhibitor. | 1996 | Nutr Cancer | pmid:8771566 |
Fellner V et al. | Steady-state rates of linoleic acid biohydrogenation by ruminal bacteria in continuous culture. | 1995 | J. Dairy Sci. | pmid:8786265 |
Murphy MG | Effects of exogenous linoleic acid on fatty acid composition, receptor-mediated cAMP formation, and transport functions in rat astrocytes in primary culture. | 1995 | Neurochem. Res. | pmid:8786824 |
Ain Baziz H et al. | Chronic heat exposure enhances fat deposition and modifies muscle and fat partition in broiler carcasses. | 1996 | Poult. Sci. | pmid:8786940 |
Carnielli VP et al. | The very low birth weight premature infant is capable of synthesizing arachidonic and docosahexaenoic acids from linoleic and linolenic acids. | 1996 | Pediatr. Res. | pmid:8798265 |
Porkkala-Sarataho E et al. | Increased oxidation resistance of atherogenic plasma lipoproteins at high vitamin E levels in non-vitamin E supplemented men. | 1996 | Atherosclerosis | pmid:8800496 |
Yamada Y et al. | Production of hydroxy fatty acid (10-hydroxy-12(Z)-octadecenoic acid) by Lactobacillus plantarum from linoleic acid and its cardiac effects to guinea pig papillary muscles. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8806645 |
Hörnsten L et al. | Dexamethasone induces bisallylic hydroxylation of polyunsaturated fatty acids by rat liver microsomes. | 1996 | Arch. Biochem. Biophys. | pmid:8806734 |
Mizushina Y et al. | Fatty acids selectively inhibit eukaryotic DNA polymerase activities in vitro. | 1996 | Biochim. Biophys. Acta | pmid:8809118 |
Ves-Losada A and Brenner RR | Long-chain fatty Acyl-CoA synthetase enzymatic activity in rat liver cell nuclei. | 1996 | Mol. Cell. Biochem. | pmid:8813703 |
Banni S et al. | A novel approach to study linoleic acid autoxidation: importance of simultaneous detection of the substrate and its derivative oxidation products. | 1996 | Free Radic. Res. | pmid:8814443 |
Kaneko T et al. | Cytotoxicity of phosphatidylcholine hydroperoxides is exerted through decomposition of fatty acid hydroperoxide moiety. | 1996 | Free Radic. Biol. Med. | pmid:8818632 |
Toborek M et al. | Linoleic acid and TNF-alpha cross-amplify oxidative injury and dysfunction of endothelial cells. | 1996 | J. Lipid Res. | pmid:8820108 |
Hatch GM and McClarty G | Regulation of cardiolipin biosynthesis in H9c2 cardiac myoblasts by cytidine 5'-triphosphate. | 1996 | J. Biol. Chem. | pmid:8824210 |
Engberg RM et al. | Inclusion of oxidized vegetable oil in broiler diets. Its influence on nutrient balance and on the antioxidative status of broilers. | 1996 | Poult. Sci. | pmid:8829233 |
Boyd NF et al. | Long-term effects of participation in a randomized trial of a low-fat, high-carbohydrate diet. | 1996 | Cancer Epidemiol. Biomarkers Prev. | pmid:8833622 |
Essien EU et al. | Lipid composition of lesser known tropical seeds. | 1995 | Plant Foods Hum Nutr | pmid:8837872 |
Glickman MH and Klinman JP | Lipoxygenase reaction mechanism: demonstration that hydrogen abstraction from substrate precedes dioxygen binding during catalytic turnover. | 1996 | Biochemistry | pmid:8841132 |
Canudas N et al. | Photodegradation of bezafibrate in aqueous media. Studies of its in vitro phototoxicity. | 1996 | Arzneimittelforschung | pmid:8842340 |
Venuta A et al. | Essential fatty acids: the effects of dietary supplementation among children with recurrent respiratory infections. | 1996 Jul-Aug | J. Int. Med. Res. | pmid:8854285 |
Okaniwa Y et al. | A high linoleate and a high alpha-linolenate diet induced changes in learning behavior of rats. Effects of a shift in diets and reversal of training stimuli. | 1996 | Biol. Pharm. Bull. | pmid:8860953 |
Hudson JA et al. | Hydration of oleic acid by a Selenomonas strain from the ovine rumen. | 1996 | Lett. Appl. Microbiol. | pmid:8862016 |
Schurz HH et al. | Products of aniline and triglycerides in oil samples associated with the toxic oil syndrome. | 1996 | Chem. Res. Toxicol. | pmid:8870988 |
Schingoethe DJ et al. | Lactational responses of dairy cows fed unsaturated fat from extruded soybeans or sunflower seeds. | 1996 | J. Dairy Sci. | pmid:8872718 |
Belury MA et al. | Dietary conjugated linoleic acid modulation of phorbol ester skin tumor promotion. | 1996 | Nutr Cancer | pmid:8875552 |
Godessart N et al. | Prostaglandin H-synthase-2 is the main enzyme involved in the biosynthesis of octadecanoids from linoleic acid in human dermal fibroblasts stimulated with interleukin-1beta. | 1996 | J. Invest. Dermatol. | pmid:8875957 |
Lammoglia MA et al. | Effects of dietary fat and season on steroid hormonal profiles before parturition and on hormonal, cholesterol, triglycerides, follicular patterns, and postpartum reproduction in Brahman cows. | 1996 | J. Anim. Sci. | pmid:8880430 |
Engels F et al. | Preferential formation of 13-hydroxylinoleic acid by human peripheral blood eosinophils. | 1996 | Prostaglandins | pmid:8880897 |
Van Nevel CJ and Demeyer DI | Influence of pH on lipolysis and biohydrogenation of soybean oil by rumen contents in vitro. | 1996 | Reprod. Nutr. Dev. | pmid:8881592 |
Eder K and Kirchgessner M | Zinc deficiency and the desaturation of linoleic acid in rats force-fed fat-free diets. | 1996 | Biol Trace Elem Res | pmid:8886317 |
Peet M et al. | Essential fatty acid deficiency in erythrocyte membranes from chronic schizophrenic patients, and the clinical effects of dietary supplementation. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8888126 |
Langley-Evans SC et al. | Influence of dietary fats upon systolic blood pressure in the rat. | 1996 | Int J Food Sci Nutr | pmid:8889627 |
Luukkainen P et al. | Impact of solid food on plasma arachidonic and docosahexaenoic acid status of term infants at 8 months of age. | 1996 | J. Pediatr. Gastroenterol. Nutr. | pmid:8890071 |
Aksnes J et al. | Long term lipid-based parenteral nutrition causes pulmonary hypertension in pigs. | 1996 | Eur J Surg | pmid:8891624 |
Ito MK and Simpson KL | The biosynthesis of omega 3 fatty acids from 18:2 omega 6 in Artemia spp. | 1996 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:8896333 |
Avery SV et al. | Copper toxicity towards Saccharomyces cerevisiae: dependence on plasma membrane fatty acid composition. | 1996 | Appl. Environ. Microbiol. | pmid:8899983 |
Lomascolo A et al. | Study of the delta 12-desaturase system of Lipomyces starkeyi. | 1996 | Lipids | pmid:8900454 |
van den Boom MA et al. | The influence of a fish oil-enriched diet on the phospholipid fatty acid turnover in the rabbit red cell membrane in vivo. | 1996 | Lipids | pmid:8900458 |
Yazu K et al. | Mechanism of lower oxidizability of eicosapentaenoate than linoleate in aqueous micelles. | 1996 | Lipids | pmid:8900464 |
Cunnane SC | The Canadian Society for Nutritional Sciences 1995 Young Scientist Award Lecture. Recent studies on the synthesis, beta-oxidation, and deficiency of linoleate and alpha-linolenate: are essential fatty acids more aptly named indispensable or conditionally dispensable fatty acids? | 1996 | Can. J. Physiol. Pharmacol. | pmid:8909772 |
Cunnane SC and Likhodii SS | 13C NMR spectroscopy and gas chromatograph--combustion--isotope ratio mass spectrometry: complementary applications in monitoring the metabolism of 13C-labelled polyunsaturated fatty acids. | 1996 | Can. J. Physiol. Pharmacol. | pmid:8909789 |
Godley PA et al. | Biomarkers of essential fatty acid consumption and risk of prostatic carcinoma. | 1996 | Cancer Epidemiol. Biomarkers Prev. | pmid:8922296 |
Loidl-Stahlhofen A et al. | Gas chromatographic-electron impact mass spectrometric screening procedure for unknown hydroxyaldehydic lipid peroxidation products after pentafluorobenzyloxime derivatization. | 1995 | J. Chromatogr. B, Biomed. Appl. | pmid:8925062 |
Mensink R | Essential and trans-fatty acids. | 1996 | Curr. Opin. Lipidol. | pmid:8925181 |
Mutanen M and Freese R | Polyunsaturated fatty acids and platelet aggregation. | 1996 | Curr. Opin. Lipidol. | pmid:8925182 |
Sugano M and Ikeda I | Metabolic interactions between essential and trans-fatty acids. | 1996 | Curr. Opin. Lipidol. | pmid:8925188 |
Glaesser D et al. | Low concentrations of cis-linoleic acid induce cell damage in epithelial cells from bovine lenses. | 1996 | Eur. J. Cell Biol. | pmid:8929567 |
Ranganath LR et al. | Increased mean platelet volume after oestrogen replacement therapy. | 1996 | Ann. Clin. Biochem. | pmid:8937589 |