Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Dry Eye Syndromes D015352 10 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Hyperpigmentation D017495 11 associated lipids
Myocardial Stunning D017682 10 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Darier Disease D007644 2 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Retinal Degeneration D012162 9 associated lipids
Dermatitis, Toxicodendron D011040 3 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Pellagra D010383 1 associated lipids
Tinea Versicolor D014010 5 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Sammon AM Maize meal, non-esterified linoleic acid, and endemic cancer of the esophagus--preliminary findings. 1999 Prostaglandins Other Lipid Mediat. pmid:10410386
Vaddadi KS The use of gamma-linolenic acid and linoleic acid to differentiate between temporal lobe epilepsy and schizophrenia. 1981 Prostaglandins Med pmid:6269135
Zhang J et al. Characteristics of fatty acid distribution is associated with colorectal cancer prognosis. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23465412
Bellini MJ et al. Effect of simvastatin on the uptake and metabolic conversion of palmitic, dihomo-gamma-linoleic and alpha-linolenic acids in A549 cells. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:14580370
Al-Turkmani MR et al. Fatty acid alterations and n-3 fatty acid supplementation in cystic fibrosis. 2007 Nov-Dec Prostaglandins Leukot. Essent. Fatty Acids pmid:18036797
Noguchi M et al. Effects of indomethacin with or without linoleic acid on human breast cancer cells in vitro. 1995 Prostaglandins Leukot. Essent. Fatty Acids pmid:7644559
Cunnane SC Commentary on the workshop statement. Essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10991770
Horrobin DF Commentary on the workshop statement: are we really sure that arachidonic acid and linoleic acid are bad things? 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10991771
Matsuo N et al. Effects of gamma-linolenic acid and its positional isomer pinolenic acid on immune parameters of brown-Norway rats. 1996 Prostaglandins Leukot. Essent. Fatty Acids pmid:8951990
Harris WS Linoleic acid and coronary heart disease. 2008 Sep-Nov Prostaglandins Leukot. Essent. Fatty Acids pmid:18951772
Gonzalez B et al. Metabolism of n -9, n -6 and n -3 fatty acids in hepatoma Morris 7777 cells. Preferential accumulation of linoleic acid in cardiolipin. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10883061
McKenzie KE et al. Omega-3 and omega-6 fatty acids and PGE2 stimulate the growth of normal but not tumor mouse mammary epithelial cells: evidence for alterations in the signaling pathways in tumor cells. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7535935
elAttar TM et al. Comparison of the inhibitory effect of polyunsaturated fatty acids on prostaglandin synthesis. II. Fibroblasts. 1990 Prostaglandins Leukot. Essent. Fatty Acids pmid:1971442
Gibson R and Makrides M α-Linolenate reduces the dietary requirement for linoleate in the growing rat. 2011 Prostaglandins Leukot. Essent. Fatty Acids pmid:22019216
Kilian M et al. Influence of conjugated and conventional linoleic acid on tumor growth and lipid peroxidation in pancreatic adenocarcinoma in hamster. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12878453
Goodfriend TL et al. An oxidized derivative of linoleic acid affects aldosterone secretion by adrenal cells in vitro. 2002 Aug-Sep Prostaglandins Leukot. Essent. Fatty Acids pmid:12324236
Smith DE and Salerno JW Selective growth inhibition of a human malignant melanoma cell line by sesame oil in vitro. 1992 Prostaglandins Leukot. Essent. Fatty Acids pmid:1502251
Glew RH et al. Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728165
Kritchevsky D Trans fatty acids and cardiovascular risk. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9430386
Renaud SC Dietary management of cardiovascular diseases. 1997 Prostaglandins Leukot. Essent. Fatty Acids pmid:9430390