Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Dry Eye Syndromes D015352 10 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Hyperpigmentation D017495 11 associated lipids
Myocardial Stunning D017682 10 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Darier Disease D007644 2 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Retinal Degeneration D012162 9 associated lipids
Dermatitis, Toxicodendron D011040 3 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Pellagra D010383 1 associated lipids
Tinea Versicolor D014010 5 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Ingkaninan K et al. Interference of linoleic acid fraction in some receptor binding assays. 1999 J. Nat. Prod. pmid:10395519
Bousquet MP et al. Enzymatic synthesis of unsaturated fatty acid glucoside esters for dermo-cosmetic applications. 1999 Biotechnol. Bioeng. pmid:10397830
Andersen LF et al. Evaluation of a food frequency questionnaire with weighed records, fatty acids, and alpha-tocopherol in adipose tissue and serum. 1999 Am. J. Epidemiol. pmid:10400557
O'Donnell VB et al. 15-Lipoxygenase catalytically consumes nitric oxide and impairs activation of guanylate cyclase. 1999 J. Biol. Chem. pmid:10400618
Dontsov AE et al. Retinal pigment epithelium pigment granules stimulate the photo-oxidation of unsaturated fatty acids. 1999 Free Radic. Biol. Med. pmid:10401607
Ding XZ et al. Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells. 1999 Biochem. Biophys. Res. Commun. pmid:10405349
Kim S et al. C/EBPbeta (NF-M) is essential for activation of the p20K lipocalin gene in growth-arrested chicken embryo fibroblasts. 1999 Mol. Cell. Biol. pmid:10409760
Sammon AM Maize meal, non-esterified linoleic acid, and endemic cancer of the esophagus--preliminary findings. 1999 Prostaglandins Other Lipid Mediat. pmid:10410386
Demmelmair H et al. Comparison of bolus versus fractionated oral applications of [13C]-linoleic acid in humans. 1999 Eur. J. Clin. Invest. pmid:10411666
Cunnane SC et al. Magnetic resonance imaging-based balance analysis of linoleate utilization during weight loss in obese humans. 1999 Lipids pmid:10419101
Belza K et al. Carbon recycling from linoleate during severe dietary linoleate deficiency. 1999 Lipids pmid:10419120
Babin F et al. Suspicion of latent delta5-desaturase and peroxisomal beta-oxidation deficiency in elderly women over 75 years of age. 1999 Lipids pmid:10419136
Calvo AM et al. Sporogenic effect of polyunsaturated fatty acids on development of Aspergillus spp. 1999 Appl. Environ. Microbiol. pmid:10427064
Yamasaki M et al. Dietary effect of conjugated linoleic acid on lipid levels in white adipose tissue of Sprague-Dawley rats. 1999 Biosci. Biotechnol. Biochem. pmid:10427699
Rudel LL Atherosclerosis and conjugated linoleic acid. 1999 Br. J. Nutr. pmid:10434843
Ahn DU et al. Effect of dietary conjugated linoleic acid on the quality characteristics of chicken eggs during refrigerated storage. 1999 Poult. Sci. pmid:10438141
Jarmuszkiewicz W et al. Identification and characterization of a protozoan uncoupling protein in Acanthamoeba castellanii. 1999 J. Biol. Chem. pmid:10438491
Freese R et al. Green tea extract decreases plasma malondialdehyde concentration but does not affect other indicators of oxidative stress, nitric oxide production, or hemostatic factors during a high-linoleic acid diet in healthy females. 1999 Eur J Nutr pmid:10443337
Beuerle T and Schwab W Metabolic profile of linoleic acid in stored apples: formation of 13(R)-hydroxy-9(Z),11(E)-octadecadienoic acid. 1999 Lipids pmid:10443970
Lundell KH et al. Plasma metabolites after a lipid load in infants with congenital heart disease. 1999 Acta Paediatr. pmid:10447129