Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
- Prostaglandins Leukot. Essent. Fatty Acids (1)
- Thorax (1)
- Am. J. Physiol., Cell Physiol. (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jung S et al. | Effect of dietary mixture of gallic acid and linoleic acid on antioxidative potential and quality of breast meat from broilers. | 2010 | Meat Sci. | pmid:20609528 |
| Feldstein AE et al. | Mass spectrometric profiling of oxidized lipid products in human nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2010 | J. Lipid Res. | pmid:20631297 |
| Wang L et al. | [Effects of linoleic acid on intracellular calcium concentration in primarily cultured rat pancreatic β-cells and underlying mechanism]. | 2010 | Sheng Li Xue Bao | pmid:21170499 |
| Khiaosa-ard R et al. | Methods of emulsifying linoleic acid in biohydrogenation studies in vitro may bias the resulting fatty acid profiles. | 2010 | Lipids | pmid:20582723 |
| Delhanty PJ et al. | Unsaturated fatty acids prevent desensitization of the human growth hormone secretagogue receptor by blocking its internalization. | 2010 | Am. J. Physiol. Endocrinol. Metab. | pmid:20587751 |
| Ross RA et al. | Differential effects of hypothalamic long-chain fatty acid infusions on suppression of hepatic glucose production. | 2010 | Am. J. Physiol. Endocrinol. Metab. | pmid:20647558 |
| Ohmori H et al. | Dietary linoleic acid and glucose enhances azoxymethane-induced colon cancer and metastases via the expression of high-mobility group box 1. | 2010 | Pathobiology | pmid:20616616 |
| Gao F et al. | Quantifying conversion of linoleic to arachidonic and other n-6 polyunsaturated fatty acids in unanesthetized rats. | 2010 | J. Lipid Res. | pmid:20622136 |
| Herdmann A et al. | Effect of dietary n-3 and n-6 PUFA on lipid composition of different tissues of German Holstein bulls and the fate of bioactive fatty acids during processing. | 2010 | J. Agric. Food Chem. | pmid:20597504 |
| Zaman MM et al. | Linoleic acid supplementation results in increased arachidonic acid and eicosanoid production in CF airway cells and in cftr-/- transgenic mice. | 2010 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:20656894 |
| Frangioudakis G et al. | Saturated- and n-6 polyunsaturated-fat diets each induce ceramide accumulation in mouse skeletal muscle: reversal and improvement of glucose tolerance by lipid metabolism inhibitors. | 2010 | Endocrinology | pmid:20660065 |
| Beezhold BL et al. | Vegetarian diets are associated with healthy mood states: a cross-sectional study in seventh day adventist adults. | 2010 | Nutr J | pmid:20515497 |
| Brito GA et al. | Lymphocytes transfer [(14)C]-labeled fatty acids to skeletal muscle in culture; modulation by exercise. | 2010 | Cell Biochem. Funct. | pmid:20517891 |
| Vukovic N et al. | An efficient synthesis and antioxidant properties of novel imino and amino derivatives of 4-hydroxy coumarins. | 2010 | Arch. Pharm. Res. | pmid:20191339 |
| Hirai S et al. | Loss of sense transgene-induced post-transcriptional gene silencing by sequential introduction of the same transgene sequences in tobacco. | 2010 | FEBS J. | pmid:20180844 |
| Pauloin A et al. | Oleate and linoleate stimulate degradation of β-casein in prolactin-treated HC11 mouse mammary epithelial cells. | 2010 | Cell Tissue Res. | pmid:20182891 |
| Gammill W et al. | Comparative study of high-linoleic acid vegetable oils for the production of conjugated linoleic acid. | 2010 | J. Agric. Food Chem. | pmid:20136082 |
| Harris W | Omega-6 and omega-3 fatty acids: partners in prevention. | 2010 | Curr Opin Clin Nutr Metab Care | pmid:20145438 |
| Goebel AS et al. | Dermal targeting using colloidal carrier systems with linoleic acid. | 2010 | Eur J Pharm Biopharm | pmid:20170728 |
| Thornhill JA et al. | Pathways for the influx of molecules into cercariae of Schistosoma mansoni during skin penetration. | 2010 | Parasitology | pmid:20128942 |
| Dailey MJ et al. | Nutrient specific feeding and endocrine effects of jejunal infusions. | 2010 | Obesity (Silver Spring) | pmid:20134410 |
| Combet E et al. | Development of an in vitro system combining aqueous and lipid phases as a tool to understand gastric nitrosation. | 2010 | Rapid Commun. Mass Spectrom. | pmid:20112267 |
| Castellanos P et al. | Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. | 2010 | Reprod. Toxicol. | pmid:20096347 |
| Coyral-Castel S et al. | Effects of unsaturated fatty acids on progesterone secretion and selected protein kinases in goat granulosa cells. | 2010 | Domest. Anim. Endocrinol. | pmid:20097509 |
| Nakamura T et al. | Excessive fat restriction might promote the recurrence of colorectal tumors. | 2010 | Nutr Cancer | pmid:20099189 |
| Beevi SS et al. | Polyphenolics profile, antioxidant and radical scavenging activity of leaves and stem of Raphanus sativus L. | 2010 | Plant Foods Hum Nutr | pmid:20072818 |
| Even P et al. | Postprandial effects of a lipid-rich meal in the rat are modulated by the degree of unsaturation of 18C fatty acids. | 2010 | Metab. Clin. Exp. | pmid:19775712 |
| Renaville B et al. | Plasma and follicular fluid fatty acid profiles in dairy cows. | 2010 | Reprod. Domest. Anim. | pmid:19055554 |
| Gholivand MB et al. | Chemical composition and antioxidant activities of the essential oil and methanol extracts of Psammogeton canescens. | 2010 | Food Chem. Toxicol. | pmid:19748545 |
| Kim BS et al. | Effect of surfactant on the production of oxygenated unsaturated fatty acids by Bacillus megaterium ALA2. | 2010 | N Biotechnol | pmid:19748603 |
| Lábaque MC et al. | Effect of age and body weight of Greater Rhea (Rhea americana) females on egg number, size and composition. | 2010 | Br. Poult. Sci. | pmid:21161792 |
| Zidi A et al. | Pleiotropic effects of the goat prolactin receptor genotype on milk fatty acid composition. | 2010 | Domest. Anim. Endocrinol. | pmid:20399061 |
| Deiana M et al. | Protective effect of simple phenols from extravirgin olive oil against lipid peroxidation in intestinal Caco-2 cells. | 2010 | Food Chem. Toxicol. | pmid:20691238 |
| Köse EO et al. | Chemical composition, antimicrobial and antioxidant activities of the essential oils of Sideritis erythrantha Boiss. and Heldr. (var. erythrantha and var. cedretorum P.H. Davis) endemic in Turkey. | 2010 | Food Chem. Toxicol. | pmid:20670669 |
| Strandvik B | Fatty acid metabolism in cystic fibrosis. | 2010 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20673710 |
| Rodrigues HG et al. | Dietary free oleic and linoleic acid enhances neutrophil function and modulates the inflammatory response in rats. | 2010 | Lipids | pmid:20730605 |
| Tel G et al. | Chemical composition of the essential oil and hexane extract of Salvia chionantha and their antioxidant and anticholinesterase activities. | 2010 | Food Chem. Toxicol. | pmid:20732375 |
| Takahashi S et al. | The occurrence of renin inhibitor in rice: isolation, identification, and structure-function relationship. | 2010 | Biosci. Biotechnol. Biochem. | pmid:20699562 |
| Vij N | Linoleic acid supplement in cystic fibrosis: friend or foe? | 2010 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:20709729 |
| Aziz AA et al. | Increasing Dietary alpha-linolenic acid enhances tissue levels of long-chain n-3 PUFA when linoleic acid intake is low in hamsters. | 2010 | Ann. Nutr. Metab. | pmid:20714137 |
| Gutiérrez-Correa J | Trypanosoma cruzi dihydrolipoamide dehydrogenase as target of reactive metabolites generated by cytochrome c/hydrogen peroxide (or linoleic acid hydroperoxide)/phenol systems. | 2010 | Free Radic. Res. | pmid:20815787 |
| Serhan Z et al. | Complete determination of natural site-specific enantio-isotopomeric excesses in linoleic acid using natural abundance deuterium 2D NMR in polypeptide mesophases. | 2010 | Chem. Commun. (Camb.) | pmid:20721385 |
| Noel JT et al. | Specific responses of Salmonella enterica to tomato varieties and fruit ripeness identified by in vivo expression technology. | 2010 | PLoS ONE | pmid:20824208 |
| Macouzet M et al. | Genetic and structural comparison of linoleate isomerases from selected food-grade bacteria. | 2010 | J. Appl. Microbiol. | pmid:20825518 |
| Collin F et al. | Experimental evidence of the reciprocal oxidation of Bovine Serum Albumin and Linoleate in aqueous solution, initiated by HO* free radicals. | 2010 | Biochimie | pmid:20685376 |
| Bolton B and Halpern BP | Orthonasal and retronasal but not oral-cavity-only discrimination of vapor-phase fatty acids. | 2010 | Chem. Senses | pmid:20100787 |
| Wu TC et al. | Fatty acid composition of Taiwanese human milk. | 2010 | J Chin Med Assoc | pmid:21093826 |
| Panagiotakos DB et al. | Fatty acids intake and depressive symptomatology in a Greek sample: an epidemiological analysis. | 2010 | J Am Coll Nutr | pmid:21677122 |
| West SG et al. | Effects of diets high in walnuts and flax oil on hemodynamic responses to stress and vascular endothelial function. | 2010 | J Am Coll Nutr | pmid:21677123 |
| Demir AS and Talpur FN | Chemoenzymatic conversion of linoleic acid into conjugated linoleic acid. | 2010 | J. Agric. Food Chem. | pmid:20058923 |
| Duckett SK and Gillis MH | Effects of oil source and fish oil addition on ruminal biohydrogenation of fatty acids and conjugated linoleic acid formation in beef steers fed finishing diets. | 2010 | J. Anim. Sci. | pmid:20348369 |
| Aluf Y et al. | Specific oxidative stress profile associated with partial striatal dopaminergic depletion by 6-hydroxydopamine as assessed by a novel multifunctional marker molecule. | 2010 | Free Radic. Res. | pmid:20370558 |
| Tume RK et al. | Enriching M. sternomandibularis with alpha-tocopherol by dietary means does not protect against the lipid oxidation caused by high-pressure processing. | 2010 | Meat Sci. | pmid:20374755 |
| Berthelot V et al. | Utilization of extruded linseed to modify fatty composition of intensively-reared lamb meat: effect of associated cereals (wheat vs. corn) and linoleic acid content of the diet. | 2010 | Meat Sci. | pmid:20374762 |
| Della Casa G et al. | Performance and fat quality of heavy pigs fed maize differing in linoleic acid content. | 2010 | Meat Sci. | pmid:20374768 |
| Friesen RW and Innis SM | Linoleic acid is associated with lower long-chain n-6 and n-3 fatty acids in red blood cell lipids of Canadian pregnant women. | 2010 | Am. J. Clin. Nutr. | pmid:19923368 |
| Runyon JB et al. | Parasitism by Cuscuta pentagona sequentially induces JA and SA defence pathways in tomato. | 2010 | Plant Cell Environ. | pmid:19930126 |
| Schwartz J et al. | Dietary intake and plasma concentrations of PUFA and LC-PUFA in breastfed and formula fed infants under real-life conditions. | 2010 | Eur J Nutr | pmid:19851802 |
| Brodhun F et al. | PpoC from Aspergillus nidulans is a fusion protein with only one active haem. | 2010 | Biochem. J. | pmid:19878096 |
| Salehipour M et al. | Polyunsaturated fatty acids and modulation of cholesterol homeostasis in THP-1 macrophage-derived foam cells. | 2010 | Int J Mol Sci | pmid:21151462 |
| Alloatti A et al. | Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. | 2010 | PLoS ONE | pmid:21151902 |
| Shen Q et al. | Antioxidant activity in vitro of the selenium-contained protein from the Se-enriched Bifidobacterium animalis 01. | 2010 | Anaerobe | pmid:20601030 |
| Zovko Koncić M et al. | Evaluation of antioxidant activities and phenolic content of Berberis vulgaris L. and Berberis croatica Horvat. | 2010 Aug-Sep | Food Chem. Toxicol. | pmid:20488218 |
| Hajlaoui H et al. | Chemical composition and biological activities of Tunisian Cuminum cyminum L. essential oil: a high effectiveness against Vibrio spp. strains. | 2010 Aug-Sep | Food Chem. Toxicol. | pmid:20488223 |
| NaÄdina VP et al. | [Changes in lipid composition of human plasma and erythrocyte membranes due to sodium hydroxybutyrate and normobaric hyperoxia during bed rest]. | 2010 Jan-Feb | Aviakosm Ekolog Med | pmid:20804001 |
| McCusker MM and Grant-Kels JM | Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids. | 2010 Jul-Aug | Clin. Dermatol. | pmid:20620762 |
| Penumetcha M et al. | Modulation of leptin levels by oxidized linoleic acid: a connection to atherosclerosis? | 2011 | J Med Food | pmid:21186986 |
| Park HG et al. | Production of conjugated linoleic acid (CLA) by Bifidobacterium breve LMC520 and its compatibility with CLA-producing rumen bacteria. | 2011 | J. Agric. Food Chem. | pmid:21192703 |
| Loizzo MR et al. | In vitro antioxidant and hypoglycemic activities of Ethiopian spice blend Berbere. | 2011 | Int J Food Sci Nutr | pmid:21599464 |
| Kruska N and Reiser G | Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. | 2011 | Neurobiol. Dis. | pmid:21570468 |
| Palmieri-Thiers C et al. | Identification of putative residues involved in the accessibility of the substrate-binding site of lipoxygenase by site-directed mutagenesis studies. | 2011 | Arch. Biochem. Biophys. | pmid:21345329 |
| Kishino S et al. | Linoleic acid isomerase in Lactobacillus plantarum AKU1009a proved to be a multi-component enzyme system requiring oxidoreduction cofactors. | 2011 | Biosci. Biotechnol. Biochem. | pmid:21307591 |
| McFarland DC et al. | Effect of lipids on avian satellite cell proliferation, differentiation and heparan sulfate proteoglycan expression. | 2011 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:21356326 |
| Retamal MA et al. | Biphasic effect of linoleic acid on connexin 46 hemichannels. | 2011 | Pflugers Arch. | pmid:21360038 |
| Shofian NM et al. | Effect of freeze-drying on the antioxidant compounds and antioxidant activity of selected tropical fruits. | 2011 | Int J Mol Sci | pmid:21845104 |
| Vedtofte MS et al. | Dietary α-linolenic acid, linoleic acid, and n-3 long-chain PUFA and risk of ischemic heart disease. | 2011 | Am. J. Clin. Nutr. | pmid:21865326 |
| Amtul Z et al. | Additive effects of fatty acid mixtures on the levels and ratio of amyloid β40/42 peptides differ from the effects of individual fatty acids. | 2011 | J. Neurosci. Res. | pmid:21748777 |
| Ilić M et al. | Thrombin inhibitors with lipid peroxidation and lipoxygenase inhibitory activities. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21757348 |
| Mito F et al. | Oxygen concentration dependence of lipid peroxidation and lipid-derived radical generation: application of profluorescent nitroxide switch. | 2011 | Free Radic. Res. | pmid:21736483 |
| Ranchordas MK et al. | A-z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--part 23. | 2011 | Br J Sports Med | pmid:21743106 |
| Kikalishvili BIu et al. | [The most biological important constances of Rkatsiteli grape oil and its effect as a 5% and 10% food-additive]. | 2011 | Georgian Med News | pmid:21778549 |
| Lee YJ and Jenkins TC | Identification of enriched conjugated linoleic acid isomers in cultures of ruminal microorganisms after dosing with 1-(13)C-linoleic acid. | 2011 | J. Microbiol. | pmid:21887646 |
| Beker BY et al. | Antioxidant protective effect of flavonoids on linoleic acid peroxidation induced by copper(II)/ascorbic acid system. | 2011 | Chem. Phys. Lipids | pmid:21925488 |
| Zhou XR et al. | Caenorhabditis elegans Delta12-desaturase FAT-2 is a bifunctional desaturase able to desaturate a diverse range of fatty acid substrates at the Delta12 and Delta15 positions. | 2011 | J. Biol. Chem. | pmid:22041902 |
| Odabasoglu F et al. | α-Lipoic acid has anti-inflammatory and anti-oxidative properties: an experimental study in rats with carrageenan-induced acute and cotton pellet-induced chronic inflammations. | 2011 | Br. J. Nutr. | pmid:21073761 |
| Akrout A et al. | Antioxidant and antitumor activities of Artemisia campestris and Thymelaea hirsuta from southern Tunisia. | 2011 | Food Chem. Toxicol. | pmid:21075159 |
| Cheng TM et al. | Haemoglobin-induced oxidative stress is associated with both endogenous peroxidase activity and H2O2 generation from polyunsaturated fatty acids. | 2011 | Free Radic. Res. | pmid:21034361 |
| Lin YH et al. | Altered essential fatty acid metabolism and composition in rat liver, plasma, heart and brain after microalgal DHA addition to the diet. | 2011 | J. Nutr. Biochem. | pmid:21111595 |
| Lam WM et al. | In Vitro characterization of low modulus linoleic acid coated strontium-substituted hydroxyapatite containing PMMA bone cement. | 2011 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:21053263 |
| Blaul B and Ruther J | How parasitoid females produce sexy sons: a causal link between oviposition preference, dietary lipids and mate choice in Nasonia. | 2011 | Proc. Biol. Sci. | pmid:21429922 |
| Gibson RA et al. | Conversion of linoleic acid and alpha-linolenic acid to long-chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of life. | 2011 | Matern Child Nutr | pmid:21366864 |
| Lauritzen L and Carlson SE | Maternal fatty acid status during pregnancy and lactation and relation to newborn and infant status. | 2011 | Matern Child Nutr | pmid:21366866 |
| Brenna JT | Animal studies of the functional consequences of suboptimal polyunsaturated fatty acid status during pregnancy, lactation and early post-natal life. | 2011 | Matern Child Nutr | pmid:21366867 |
| Briend A et al. | Fatty acid status in early life in low-income countries--overview of the situation, policy and research priorities. | 2011 | Matern Child Nutr | pmid:21366873 |
| Blasbalg TL et al. | Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century. | 2011 | Am. J. Clin. Nutr. | pmid:21367944 |
| Aewsiri T et al. | Surface activity and molecular characteristics of cuttlefish skin gelatin modified by oxidized linoleic acid. | 2011 | Int. J. Biol. Macromol. | pmid:21334373 |
| Edris AE | The chemical composition and the content of volatile oil: potential factors that can contribute to the oxidative stability of Nigella sativa L. crude oil. | 2011 | J Diet Suppl | pmid:22432633 |
| Salem N and Kuratko CN | Lack of evidence for increased α-linolenic acid metabolism in vegetarians. | 2011 | Am. J. Clin. Nutr. | pmid:21430120 |
| Carrillo C et al. | Oleic acid versus linoleic and α-linolenic acid. different effects on Ca2+ signaling in rat thymocytes. | 2011 | Cell. Physiol. Biochem. | pmid:21471726 |
| Subbaiah PV et al. | Incorporation profiles of conjugated linoleic acid isomers in cell membranes and their positional distribution in phospholipids. | 2011 | Biochim. Biophys. Acta | pmid:20920595 |