Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gardner HW and Grove MJ | Method to produce 9(S)-hydroperoxides of linoleic and linolenic acids by maize lipoxygenase. | 2001 | Lipids | pmid:11432467 |
Chakrabarti KB et al. | Modification of doxorubicin-induced cardiotoxicity: effect of essential fatty acids and ICRF-187 (dexrazoxane). | 2001 | Eur. J. Cancer | pmid:11435077 |
Terpstra AH | Differences between humans and mice in efficacy of the body fat lowering effect of conjugated linoleic acid: role of metabolic rate. | 2001 | J. Nutr. | pmid:11435531 |
Banni S et al. | Distribution of conjugated linoleic acid and metabolites in different lipid fractions in the rat liver. | 2001 | J. Lipid Res. | pmid:11441132 |
Heydeck D et al. | Oxidation of LDL by rabbit and human 15-lipoxygenase: prevalence of nonenzymatic reactions. | 2001 | J. Lipid Res. | pmid:11441135 |
Aljada A et al. | Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action? | 2001 | J. Clin. Endocrinol. Metab. | pmid:11443197 |
Almario RU et al. | Effects of walnut consumption on plasma fatty acids and lipoproteins in combined hyperlipidemia. | 2001 | Am. J. Clin. Nutr. | pmid:11451720 |
Whitehouse AS and Tisdale MJ | Downregulation of ubiquitin-dependent proteolysis by eicosapentaenoic acid in acute starvation. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11453634 |
Yu L | Free radical scavenging properties of conjugated linoleic acids. | 2001 | J. Agric. Food Chem. | pmid:11453790 |
Morris A et al. | The role of n-6 polyunsaturated fat in stable asthmatics. | 2001 | J Asthma | pmid:11456384 |
Thiel-Cooper RL et al. | Conjugated linoleic acid changes swine performance and carcass composition. | 2001 | J. Anim. Sci. | pmid:11465369 |
Ramaswamy N et al. | Short communication: Consumer evaluation of milk high in conjugated linoleic acid. | 2001 | J. Dairy Sci. | pmid:11467809 |
Sijben JW et al. | Interactions and antigen dependence of dietary n-3 and n-6 polyunsaturated fatty acids on antibody responsiveness in growing layer hens. | 2001 | Poult. Sci. | pmid:11469650 |
Del Prado M et al. | Contribution of dietary and newly formed arachidonic acid to human milk lipids in women eating a low-fat diet. | 2001 | Am. J. Clin. Nutr. | pmid:11470727 |
Kachhap SK et al. | Effect of omega-3 fatty acid (docosahexanoic acid) on BRCA1 gene expression and growth in MCF-7 cell line. | 2001 | Cancer Biother. Radiopharm. | pmid:11471489 |
Malkowski MG et al. | Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1. | 2001 | J. Biol. Chem. | pmid:11477109 |
Risérus U et al. | Conjugated linoleic acid (CLA) reduced abdominal adipose tissue in obese middle-aged men with signs of the metabolic syndrome: a randomised controlled trial. | 2001 | Int. J. Obes. Relat. Metab. Disord. | pmid:11477497 |
Spector AA | Plasma free fatty acid and lipoproteins as sources of polyunsaturated fatty acid for the brain. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478370 |
Gupta SV and Khosla P | Palmitic and stearic acids similarly affect plasma lipoprotein metabolism in cynomolgus monkeys fed diets with adequate levels of linoleic acid. | 2001 | J. Nutr. | pmid:11481404 |
Phoon MC et al. | Linoleic and linolelaidic acids differentially influence proliferation and apoptosis of MOLT-4 leukaemia cells. | 2001 | Cell Biol. Int. | pmid:11482901 |
Seddon JM et al. | Dietary fat and risk for advanced age-related macular degeneration. | 2001 | Arch. Ophthalmol. | pmid:11483088 |
Gardner HW and Deighton N | Effect of 4-hydroxy-2(E)-nonenal on soybean lipoxygenase-1. | 2001 | Lipids | pmid:11485167 |
Takeda M et al. | Preference for corn oil in olfactory-blocked mice in the conditioned place preference test and the two-bottle choice test. | 2001 | Life Sci. | pmid:11487096 |
Vancassel S et al. | Plasma fatty acid levels in autistic children. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11487301 |
Harris MA et al. | Effects of conjugated linoleic acids and docosahexaenoic acid on rat liver and reproductive tissue fatty acids, prostaglandins and matrix metalloproteinase production. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11487304 |
Sewram V et al. | Supercritical fluid extraction and analysis of compounds from Clivia miniata for uterotonic activity. | 2001 | Planta Med. | pmid:11488461 |
Chen ZY et al. | Accumulation and apparent oxidation of cis,trans-18 : 2 isomers relative to linoleic acid in rats. | 2001 | Br. J. Nutr. | pmid:11502239 |
Chang W et al. | Induction of cardiac FABP gene expression by long chain fatty acids in cultured rat muscle cells. | 2001 | Mol. Cell. Biochem. | pmid:11506175 |
Févrie P et al. | Separation of glyceride positional isomers by silver ion chromatography. | 2001 | J Chromatogr A | pmid:11510559 |
Prescha A et al. | Increase in lipid content in potato tubers modified by 14-3-3 gene overexpression. | 2001 | J. Agric. Food Chem. | pmid:11513640 |
Lin Y et al. | Conjugated linoleic acid isomers have differential effects on triglyceride secretion in Hep G2 cells. | 2001 | Biochim. Biophys. Acta | pmid:11514234 |
Pérez-Pé R et al. | Semen plasma proteins prevent cold-shock membrane damage to ram spermatozoa. | 2001 | Theriogenology | pmid:11516122 |
Ramsay TG et al. | Dietary conjugated linoleic acid alters fatty acid composition of pig skeletal muscle and fat. | 2001 | J. Anim. Sci. | pmid:11518224 |
Wiegand BR et al. | Conjugated linoleic acid improves feed efficiency, decreases subcutaneous fat, and improves certain aspects of meat quality in stress-genotype pigs. | 2001 | J. Anim. Sci. | pmid:11518228 |
Kucuk O et al. | Effect of forage:concentrate ratio on ruminal digestion and duodenal flow of fatty acids in ewes. | 2001 | J. Anim. Sci. | pmid:11518234 |
Abu-Ghazaleh AA et al. | Conjugated linoleic acid and other beneficial fatty acids in milk fat from cows fed soybean meal, fish meal, or both. | 2001 | J. Dairy Sci. | pmid:11518309 |
Cubillos MA et al. | Kinetics of peroxidation of linoleic acid incorporated into DPPC vesicles initiated by the thermal decomposition of 2,2'-azobis(2-amidinopropane) dihydrochloride. | 2001 | Chem. Phys. Lipids | pmid:11518571 |
Kelley DS et al. | Dietary supplementation with conjugated linoleic acid increased its concentration in human peripheral blood mononuclear cells, but did not alter their function. | 2001 | Lipids | pmid:11521964 |
Pratt VC et al. | Fatty acid content of plasma lipids and erythrocyte phospholipids are altered following burn injury. | 2001 | Lipids | pmid:11521965 |
Bryan DL et al. | Incorporation of alpha-linolenic acid and linoleic acid into human respiratory epithelial cell lines. | 2001 | Lipids | pmid:11521969 |
Olsson U et al. | Changes in matrix proteoglycans induced by insulin and fatty acids in hepatic cells may contribute to dyslipidemia of insulin resistance. | 2001 | Diabetes | pmid:11522680 |
Aro A et al. | Inverse association between dietary and serum conjugated linoleic acid and risk of breast cancer in postmenopausal women. | 2000 | Nutr Cancer | pmid:11525591 |
Brown JM et al. | Trans-10, cis-12, but not cis-9, trans-11, conjugated linoleic acid attenuates lipogenesis in primary cultures of stromal vascular cells from human adipose tissue. | 2001 | J. Nutr. | pmid:11533273 |
Bassaganya-Riera J et al. | Dietary conjugated linoleic acid modulates phenotype and effector functions of porcine CD8(+) lymphocytes. | 2001 | J. Nutr. | pmid:11533281 |
Watkins BA et al. | Designed eggs containing conjugated linoleic acids and omega-3 polyunsaturated fatty acids. | 2001 | World Rev Nutr Diet | pmid:11545041 |
McKay MC and Worley JF | Linoleic acid both enhances activation and blocks Kv1.5 and Kv2.1 channels by two separate mechanisms. | 2001 | Am. J. Physiol., Cell Physiol. | pmid:11546665 |
Kang K and Pariza MW | trans-10,cis-12-Conjugated linoleic acid reduces leptin secretion from 3T3-L1 adipocytes. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11554738 |
Borecký J et al. | Functional reconstitution of Arabidopsis thaliana plant uncoupling mitochondrial protein (AtPUMP1) expressed in Escherichia coli. | 2001 | FEBS Lett. | pmid:11566183 |
Gurvitz A et al. | Degradation of conjugated linoleic acid isomers in the yeast Saccharomyces cerevisiae. | 2001 | Biochim. Biophys. Acta | pmid:11566445 |
Rainio A et al. | Reduction of linoleic acid inhibition in production of conjugated linoleic acid by Propionibacterium freudenreichii ssp. shermanii. | 2001 | Can. J. Microbiol. | pmid:11575500 |
Kelly GS | Conjugated linoleic acid: a review. | 2001 | Altern Med Rev | pmid:11578253 |
Poulos SP et al. | Pre- and postnatal dietary conjugated linoleic acid alters adipose development, body weight gain and body composition in Sprague-Dawley rats. | 2001 | J. Nutr. | pmid:11584096 |
Berry EM | Who's afraid of n-6 polyunsaturated fatty acids? Methodological considerations for assessing whether they are harmful. | 2001 | Nutr Metab Cardiovasc Dis | pmid:11590994 |
Costarelli V and Sanders TA | Acute effects of dietary fat composition on postprandial plasma bile acid and cholecystokinin concentrations in healthy premenopausal women. | 2001 | Br. J. Nutr. | pmid:11591234 |
Zambell KL et al. | Conjugated linoleic acid supplementation in humans: effects on fatty acid and glycerol kinetics. | 2001 | Lipids | pmid:11592726 |
Smedman A and Vessby B | Conjugated linoleic acid supplementation in humans--metabolic effects. | 2001 | Lipids | pmid:11592727 |
Berthoud HR et al. | Food-related gastrointestinal signals activate caudal brainstem neurons expressing both NMDA and AMPA receptors. | 2001 | Brain Res. | pmid:11595203 |
Bézaire V et al. | Effects of fasting on muscle mitochondrial energetics and fatty acid metabolism in Ucp3(-/-) and wild-type mice. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11595653 |
Ruiz-Sanz JI et al. | Polyunsaturated fatty acid deficiency during dietary treatment of very long-chain acyl-CoA dehydrogenase deficiency. Rescue with soybean oil. | 2001 | J. Inherit. Metab. Dis. | pmid:11596652 |
Goffman FD and Böhme T | Relationship between fatty acid profile and vitamin E content in maize hybrids (Zea mays L.). | 2001 | J. Agric. Food Chem. | pmid:11600056 |
Haastrup A et al. | Lipids stimulate the production of 6-keto-prostaglandin f(1alpha) in human dorsal hand veins. | 2001 | Hypertension | pmid:11641299 |
Butovich IA et al. | [Characteristics of the aggregative state of the substrate in the reaction of 5-lipoxygenase oxidation of linoleic acid]. | 2001 Mar-Apr | Ukr Biokhim Zh (1999) | pmid:11642042 |
Kozachenko AI et al. | Characteristics of beta-carotene-induced inhibition of free radical oxidation of fatty acids with different degree of unsaturation. | 2001 Jul-Aug | Dokl. Biochem. Biophys. | pmid:11665681 |
Kolesnichenko AV et al. | Influence of CSP 310 and CSP 310-like proteins from cereals on mitochondrial energetic activity and lipid peroxidation in vitro and in vivo. | 2001 | BMC Plant Biol. | pmid:11667950 |
Rahamatalla AB et al. | Changes in fatty acids composition during seed growth and physicochemical characteristics of oil extracted from four safflower cultivars. | 2001 | Plant Foods Hum Nutr | pmid:11678443 |
Djoussé L et al. | Relation between dietary linolenic acid and coronary artery disease in the National Heart, Lung, and Blood Institute Family Heart Study. | 2001 | Am. J. Clin. Nutr. | pmid:11684529 |
López Bote CJ et al. | Effect of dietary linoleic acid concentration and vitamin E supplementation on cell desquamation and susceptibility to oxidative damage of pig jejunal mucosa. | 2001 | J Anim Physiol Anim Nutr (Berl) | pmid:11686769 |
Aleynik MK and Lieber CS | Dilinoleoylphosphatidylcholine decreases ethanol-induced cytochrome P4502E1. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11689017 |
Collomb M et al. | Conjugated linoleic acid and trans fatty acid composition of cows' milk fat produced in lowlands and highlands. | 2001 | J. Dairy Res. | pmid:11694053 |
Finley JW and Davis CD | Manganese absorption and retention in rats is affected by the type of dietary fat. | 2001 | Biol Trace Elem Res | pmid:11697763 |
Kelavkar UP et al. | Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis. | 2001 | Carcinogenesis | pmid:11698337 |
Ramaswamy N et al. | Composition and flavor of milk and butter from cows fed fish oil, extruded soybeans, or their combination. | 2001 | J. Dairy Sci. | pmid:11699444 |
Hagenlocher T et al. | Influence of dietary fatty acid, vegetable, and vitamin intake on etheno-DNA adducts in white blood cells of healthy female volunteers: a pilot study. | 2001 | Cancer Epidemiol. Biomarkers Prev. | pmid:11700267 |
O'Quinn PR et al. | Conjugated linoleic acid. | 2000 | Anim Health Res Rev | pmid:11706843 |
Cigliano L et al. | Estradiol esterification in the human preovulatory follicle. | 2001 | Steroids | pmid:11711117 |
Gadducci A et al. | Malnutrition and cachexia in ovarian cancer patients: pathophysiology and management. | 2001 Jul-Aug | Anticancer Res. | pmid:11712791 |
Strandvik B et al. | Essential fatty acid deficiency in relation to genotype in patients with cystic fibrosis. | 2001 | J. Pediatr. | pmid:11713441 |
Moran JH et al. | Linoleic acid prevents chloride influx and cellular lysis in rabbit renal proximal tubules exposed to mitochondrial toxicants. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11714247 |
Calaf RE et al. | Automated strong cation exchange extraction of fatty acid esters of 3-(N-phenylamino)-1,2-propanediol from oil samples for routine quantification by HPLC-APCI/MS/MS. | 2001 | J. Agric. Food Chem. | pmid:11714286 |
Tallman KA et al. | Kinetic products of linoleate peroxidation: rapid beta-fragmentation of nonconjugated peroxyls. | 2001 | J. Am. Chem. Soc. | pmid:11716752 |
Palinski W et al. | Maternal hypercholesterolemia and treatment during pregnancy influence the long-term progression of atherosclerosis in offspring of rabbits. | 2001 | Circ. Res. | pmid:11717155 |
Milani G et al. | Respiratory chain network in mitochondria of Candida parapsilosis: ADP/O appraisal of the multiple electron pathways. | 2001 | FEBS Lett. | pmid:11718721 |
Weber TE et al. | Evaluation of conjugated linoleic acid and dietary antibiotics as growth promotants in weanling pigs. | 2001 | J. Anim. Sci. | pmid:11721832 |
Calder PC | Polyunsaturated fatty acids, inflammation, and immunity. | 2001 | Lipids | pmid:11724453 |
Makrides M et al. | Perinatal characteristics may influence the outcome of visual acuity. | 2001 | Lipids | pmid:11724461 |
Cunnane SC | Application of new methods and analytical approaches to research on polyunsaturated fatty acid homeostasis. | 2001 | Lipids | pmid:11724470 |
Thom E et al. | Conjugated linoleic acid reduces body fat in healthy exercising humans. | 2001 Sep-Oct | J. Int. Med. Res. | pmid:11725826 |
Glew RH et al. | Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728165 |
Villalpando S et al. | [13C]linoleic acid oxidation and transfer into milk in stunted lactating women with contrasting body mass indexes. | 2001 | Am. J. Clin. Nutr. | pmid:11729835 |
Park Y and Pariza MW | The effects of dietary conjugated nonadecadienoic acid on body composition in mice. | 2001 | Biochim. Biophys. Acta | pmid:11731328 |
Peters JM et al. | Influence of conjugated linoleic acid on body composition and target gene expression in peroxisome proliferator-activated receptor alpha-null mice. | 2001 | Biochim. Biophys. Acta | pmid:11731333 |
Lee BD et al. | Nutritive and economic values of high oil corn in layer diet. | 2001 | Poult. Sci. | pmid:11732667 |
Watanabe T et al. | Production and chemiluminescent free radical reactions of glyoxal in lipid peroxidation of linoleic acid by the ligninolytic enzyme, manganese peroxidase. | 2001 | Eur. J. Biochem. | pmid:11733005 |
Gustafsson MC et al. | Fatty-acid-displaced transcriptional repressor, a conserved regulator of cytochrome P450 102 transcription in Bacillus species. | 2001 | Arch. Microbiol. | pmid:11734890 |
Pelikánová T et al. | Serum phospholipid fatty acid composition and insulin action in type 2 diabetic patients. | 2001 | Metab. Clin. Exp. | pmid:11735096 |
Fernández-Real JM et al. | Circulating granulocyte-macrophage colony-stimulating factor and serum fatty acid composition in men and women. | 2001 | Metab. Clin. Exp. | pmid:11735097 |
Büyükokuroğlu ME et al. | In vitro antioxidant properties of dantrolene sodium. | 2001 | Pharmacol. Res. | pmid:11735355 |
Melamed-Frank M et al. | Structure-function analysis of the antioxidant properties of haptoglobin. | 2001 | Blood | pmid:11739174 |
Coles B et al. | Nitrolinoleate inhibits platelet activation by attenuating calcium mobilization and inducing phosphorylation of vasodilator-stimulated phosphoprotein through elevation of cAMP. | 2002 | J. Biol. Chem. | pmid:11748216 |
Pirtle IL et al. | Molecular cloning and functional expression of the gene for a cotton Delta-12 fatty acid desaturase (FAD2). | 2001 | Biochim. Biophys. Acta | pmid:11750064 |