Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Dry Eye Syndromes D015352 10 associated lipids
Anemia, Iron-Deficiency D018798 6 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Muscular Dystrophy, Duchenne D020388 11 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Hyperpigmentation D017495 11 associated lipids
Myocardial Stunning D017682 10 associated lipids
Mitochondrial Myopathies D017240 13 associated lipids
Darier Disease D007644 2 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Retinal Degeneration D012162 9 associated lipids
Dermatitis, Toxicodendron D011040 3 associated lipids
Pregnancy Complications, Neoplastic D011252 4 associated lipids
Endometrial Neoplasms D016889 30 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Pellagra D010383 1 associated lipids
Tinea Versicolor D014010 5 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Nakagawa Y [Metabolism and biological function of cardiolipin]. 2013 Yakugaku Zasshi pmid:23649397
Toda S et al. [Inhibitory effects of methanol extracts of crude drugs on the air oxidation of linoleic acid]. 1984 Yakugaku Zasshi pmid:6491877
Fujii M Pathogenesis of Diet-induced Atopic Dermatitis in Hairless Mice. 2017 Yakugaku Zasshi pmid:28049895
Okuyama H [Need to change the direction of cholesterol-related medication--a problem of great urgency]. 2005 Yakugaku Zasshi pmid:16272805
Byczkowski JZ and Kulkarni AP Linoleate-dependent co-oxygenation of benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol by rat cytosolic lipoxygenase. 1992 Xenobiotica pmid:1413876
Cardoso CR et al. Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wounds. 2004 Mar-Apr Wound Repair Regen pmid:15086775
Holman RT Highpoints in an affair with polyunsaturated fatty acids. 1991 World Rev Nutr Diet pmid:2053355
Okuyama H et al. Why isn't the causal relationship between linoleic acid and mortalities from coronary heart disease and stroke revealed by clinical studies? 2007 World Rev Nutr Diet pmid:17167283
Okuyama H et al. Mechanisms by which dietary fats affect coronary heart disease mortality. 2007 World Rev Nutr Diet pmid:17167284
Okuyama H et al. Cancers common in the USA are stimulated by omega 6 fatty acids and large amounts of animal fats, but suppressed by omega 3 fatty acids and cholesterol. 2007 World Rev Nutr Diet pmid:17167285