Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Hyperlipoproteinemia Type II D006938 22 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Helicobacter Infections D016481 21 associated lipids
Cachexia D002100 21 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Tuberculosis D014376 20 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Brain Edema D001929 20 associated lipids
Parkinsonian Disorders D020734 20 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Brynes AE et al. Diet-induced change in fatty acid composition of plasma triacylglycerols is not associated with change in glucagon-like peptide 1 or insulin sensitivity in people with type 2 diabetes. 2000 Am. J. Clin. Nutr. pmid:11063437
Hennig B et al. Linoleic acid activates nuclear transcription factor-kappa B (NF-kappa B) and induces NF-kappa B-dependent transcription in cultured endothelial cells. 1996 Am. J. Clin. Nutr. pmid:8602587
KRAUSE RF LIVER LIPIDS IN A CASE OF HYPERVITAMINOSIS A. 1965 Am. J. Clin. Nutr. pmid:14301352
DeLany JP et al. Differential oxidation of individual dietary fatty acids in humans. 2000 Am. J. Clin. Nutr. pmid:11010930
O'Connell ED et al. Diet and risk factors for age-related maculopathy. 2008 Am. J. Clin. Nutr. pmid:18326611
Granot E et al. Breast-fed and formula-fed infants do not differ in immunocompetent cell cytokine production despite differences in cell membrane fatty acid composition. 2000 Am. J. Clin. Nutr. pmid:11063450
Rioux FM and Innis SM Arachidonic acid concentrations in plasma and liver phospholipid and cholesterol esters of piglets raised on formulas with different linoleic and linolenic acid contents. 1992 Am. J. Clin. Nutr. pmid:1609747
Rudel LL et al. Dietary polyunsaturated fat modifies low-density lipoproteins and reduces atherosclerosis of nonhuman primates with high and low diet responsiveness. 1995 Am. J. Clin. Nutr. pmid:7625361
Horrobin DF Essential fatty acid metabolism and its modification in atopic eczema. 2000 Am. J. Clin. Nutr. pmid:10617999
Murphy J et al. Fat malabsorption in cystic fibrosis patients. 1999 Am. J. Clin. Nutr. pmid:10539762
Terpstra AH Effect of conjugated linoleic acid on body composition and plasma lipids in humans: an overview of the literature. 2004 Am. J. Clin. Nutr. pmid:14985207
Cunnane SC Diodoquin and linoleic acid absorption in zinc deficiency. 1981 Am. J. Clin. Nutr. pmid:6792900
Chevrot M et al. Obesity interferes with the orosensory detection of long-chain fatty acids in humans. 2014 Am. J. Clin. Nutr. pmid:24522446
Goyens PL et al. Conversion of alpha-linolenic acid in humans is influenced by the absolute amounts of alpha-linolenic acid and linoleic acid in the diet and not by their ratio. 2006 Am. J. Clin. Nutr. pmid:16825680
Cunnane SC et al. Beta-oxidation of linoleate in obese men undergoing weight loss. 2001 Am. J. Clin. Nutr. pmid:11273844
Elias SL and Innis SM Infant plasma trans, n-6, and n-3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and length. 2001 Am. J. Clin. Nutr. pmid:11273857
Seidelin KN et al. Percentage distribution of fatty acids in subcutaneous adipose tissue of patients with peptic ulcer disease. 1993 Am. J. Clin. Nutr. pmid:8416668
Horrobin DF Fatty acid metabolism in health and disease: the role of delta-6-desaturase. 1993 Am. J. Clin. Nutr. pmid:8386433
Martinez GA et al. Nutrient intakes of American infants and children fed cow's milk or infant formula. 1985 Am. J. Dis. Child. pmid:4036886
BAUGHAN MA et al. TIME, TEMPERATURE EXPOSURE TO AIR OF MILK PREPARATIONS. EFFECT ON FATTY ACIDS. 1963 Am. J. Dis. Child. pmid:14063701
van Staveren WA et al. Validity of the fatty acid composition of subcutaneous fat tissue microbiopsies as an estimate of the long-term average fatty acid composition of the diet of separate individuals. 1986 Am. J. Epidemiol. pmid:3946391
Andersen LF et al. Evaluation of a food frequency questionnaire with weighed records, fatty acids, and alpha-tocopherol in adipose tissue and serum. 1999 Am. J. Epidemiol. pmid:10400557
Seidell JC et al. Polyunsaturated fatty acids in adipose tissue in European men aged 38 years in relation to serum lipids, smoking habits, and fat distribution. 1991 Am. J. Epidemiol. pmid:1951263
Jacobsen BK et al. Re: "Comparison of measures of fatty acid intake by subcutaneous fat aspirate, food frequency questionnaire, and diet records in a free-living population of US men". 1993 Am. J. Epidemiol. pmid:8333420
Brosnan MJ and Carkner RD Hepatic effects of a fructose diet in the stroke-prone spontaneously hypertensive rat. 2008 Am. J. Hypertens. pmid:18437120
Zhang HY et al. A high sucrose, high linoleic acid diet potentiates hypertension in the Dahl salt sensitive rat. 1999 Am. J. Hypertens. pmid:10090346
Taylor EN et al. Fatty acid intake and incident nephrolithiasis. 2005 Am. J. Kidney Dis. pmid:15685503
Ascherio A Epidemiologic studies on dietary fats and coronary heart disease. 2002 Am. J. Med. pmid:12566133
Weiss LA et al. The omega-6 fatty acid linoleic acid is associated with risk of gastroschisis: a novel dietary risk factor. 2012 Am. J. Med. Genet. A pmid:22315197
SCHWARTZ S et al. LIPID THROMBOPLASTINS AND MYOCARDIAL INFARCTION. 1965 Am. J. Med. Sci. pmid:14254823
Brush MG et al. Abnormal essential fatty acid levels in plasma of women with premenstrual syndrome. 1984 Am. J. Obstet. Gynecol. pmid:6091462
Kääpä P et al. Dietary fatty acids and platelet thromboxane production in puerperal women and their offspring. 1986 Am. J. Obstet. Gynecol. pmid:3089014
MacKenzie LW et al. Prostacyclin biosynthesis by cultured human myometrial smooth muscle cells: dependency on arachidonic or linoleic acid in the culture medium. 1988 Am. J. Obstet. Gynecol. pmid:3144917
Vaughan JE and Walsh SW Neutrophils from pregnant women produce thromboxane and tumor necrosis factor-alpha in response to linoleic acid and oxidative stress. 2005 Am. J. Obstet. Gynecol. pmid:16150282
Liu H et al. Transient receptor potential vanilloid 1 gene deficiency ameliorates hepatic injury in a mouse model of chronic binge alcohol-induced alcoholic liver disease. 2015 Am. J. Pathol. pmid:25447051
McEntee MF et al. Dietary n-3 polyunsaturated fatty acids enhance hormone ablation therapy in androgen-dependent prostate cancer. 2008 Am. J. Pathol. pmid:18556778
Pandey NR et al. An induction in hepatic HDL secretion associated with reduced ATPase expression. 2009 Am. J. Pathol. pmid:19717637
Sarel I and Widmaier EP Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. 1995 Am. J. Physiol. pmid:7611525
Rosenblum WI Unsaturated fatty acids and cyclooxygenase inhibitors: effects on pial arterioles. 1982 Am. J. Physiol. pmid:6801999
Meikle AW et al. Nonesterified fatty acids modulate steroidogenesis in mouse Leydig cells. 1989 Am. J. Physiol. pmid:2558577
West DB et al. Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse. 1998 Am. J. Physiol. pmid:9728060
Jensen MD et al. Measurement of non-steady-state free fatty acid turnover. 1990 Am. J. Physiol. pmid:2405695
Kerner J et al. Impaired gut lipid absorptive capacity after trauma-hemorrhage and resuscitation. 1995 Am. J. Physiol. pmid:7485605
ERWIN ES and STERNER W DIETARY LIPIDS AND FATTY ACID DEPOSITION IN VARIOUS CALF TISSUES. 1963 Am. J. Physiol. pmid:14084975
Thomas ME et al. Metabolic effects of fatty acid-bearing albumin on a proximal tubule cell line. 1995 Am. J. Physiol. pmid:7611458
WILSON JD Relation between dietary cholesterol and bile acid excretion in the rat. 1962 Am. J. Physiol. pmid:14001040
Reddy SR et al. Effect of linoleic acid infusion on blood pressure in normotensive and hypertensive rats. 1989 Am. J. Physiol. pmid:2764141
Bogdanov KY et al. Modulation of the transient outward current in adult rat ventricular myocytes by polyunsaturated fatty acids. 1998 Am. J. Physiol. pmid:9486261
Devor DC and Frizzell RA Modulation of K+ channels by arachidonic acid in T84 cells. II. Activation of a Ca(2+)-independent K+ channel. 1998 Am. J. Physiol. pmid:9458723
Sebokova E et al. Modulation of receptor-mediated gonadotropin action in rat testes by dietary fat. 1988 Am. J. Physiol. pmid:2897795