Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Infant, Newborn, Diseases D007232 9 associated lipids
Infertility D007246 3 associated lipids
Infertility, Male D007248 11 associated lipids
Inflammation D007249 119 associated lipids
Insulin Resistance D007333 99 associated lipids
Keloid D007627 12 associated lipids
Darier Disease D007644 2 associated lipids
Kidney Diseases D007674 29 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Haycock JC and Evers AS Altered phosphoinositide fatty acid composition, mass and metabolism in brain essential fatty acid deficiency. 1988 Biochim. Biophys. Acta pmid:2833931
Babin F et al. Plasma fatty acid composition and lipid peroxide levels in children with paucity of interlobular bile ducts. 1988 Ann. Nutr. Metab. pmid:3195990
Høy CE and Hølmer G Dietary linoleic acid and the fatty acid profiles in rats fed partially hydrogenated marine oils. 1988 Lipids pmid:3200121
Hubbard NE et al. Inhibition of growth and linoleate-enhanced metastasis of a transplantable mouse mammary tumor by indomethacin. 1988 Cancer Lett. pmid:3203321
Kulkarni AP and Cook DC Hydroperoxidase activity of lipoxygenase: a potential pathway for xenobiotic metabolism in the presence of linoleic acid. 1988 Res. Commun. Chem. Pathol. Pharmacol. pmid:3141996
Hicks M et al. Catalysis of lipid peroxidation by glucose and glycosylated collagen. 1988 Biochem. Biophys. Res. Commun. pmid:3126742
Bandyopadhyay GK et al. Proliferative effects of insulin and epidermal growth factor on mouse mammary epithelial cells in primary culture. Enhancement by hydroxyeicosatetraenoic acids and synergism with prostaglandin E2. 1988 J. Biol. Chem. pmid:3286636
Truchetet E et al. [Skin changes, pathophysiology and therapy in deficiency of essential fatty acids]. 1988 Z. Hautkr. pmid:3291438
Chapkin RS et al. Inability of murine peritoneal macrophages to convert linoleic acid into arachidonic acid. Evidence of chain elongation. 1988 J. Immunol. pmid:3127464
Beaumelle BD and Vial HJ Uninfected red cells from malaria-infected blood: alteration of fatty acid composition involving a serum protein: an in vivo and in vitro study. 1988 In Vitro Cell. Dev. Biol. pmid:3294227
Bartels T et al. Correlations between endogenous prostaglandin E formation in the bone and spongiosa density. 1988 Biomed. Biochim. Acta pmid:3248114
De Deckere EA et al. Effects of type and amount of dietary fat on rabbit and rat lymphocyte proliferation in vitro. 1988 J. Nutr. pmid:3257261
Perez RV et al. Dietary immunoregulation of transfusion-induced immunosuppression. 1988 Transplantation pmid:3258077
Tiwari RK et al. Influence of genotype on the phospholipid fatty acid composition of splenic T and B lymphocytes in MRL/MpJ-lpr/lpr mice. 1988 Immunol. Lett. pmid:3258845
Singh B et al. Effect of high/low dietary linoleic acid levels on the function and fatty acid composition of T-lymphocytes of normal and diabetic rats. 1988 Diabetes Res. pmid:3265900
Dietary fat and insulin receptor function in rat adipocytes. 1988 Nutr. Rev. pmid:3277091
Collier A et al. Reduced free radical activity detected by decreased diene conjugates in insulin-dependent diabetic patients. 1988 Diabet. Med. pmid:2975566
Bartels T et al. [Effect of linoleic acid in food on spongioid bone density and prostaglandin biosynthesis in bones]. 1988 Beitr Orthop Traumatol pmid:3228436
Stephens RJ et al. Lipid peroxidation and retinal phototoxic degeneration. 1988 Basic Life Sci. pmid:2977946
Whitehead CC and Herron KM Fatty acid requirements of breeding turkeys. 1988 Br. Poult. Sci. pmid:3233502
Parsons HG et al. Supplemental calories improve essential fatty acid deficiency in cystic fibrosis patients. 1988 Pediatr. Res. pmid:3211621
Schächtele C et al. Stimulus-dependent inhibition of platelet aggregation by the protein kinase C inhibitors polymyxin B, H-7 and staurosporine. 1988 Biochem. Biophys. Res. Commun. pmid:2831891
Loesberg C et al. Superoxide anion production by alveolar macrophages of guinea pigs fed different diets in a model of atopy. 1988 Agents Actions pmid:2833083
Manku MS et al. Changes in human plasma essential fatty acid levels as a result of administration of linoleic acid and gamma-linolenic acid. 1988 Eur J Clin Nutr pmid:2836190
Brasitus TA and Dudeja PK Effect of hypothyroidism on the lipid composition and fluidity of rat colonic apical plasma membranes. 1988 Biochim. Biophys. Acta pmid:3128322
Nilsson A and Landin B Metabolism of chylomicron arachidonic and linoleic acid in the rat. 1988 Biochim. Biophys. Acta pmid:3128335
Cutts JL and Melnykovych G Defective utilization of cholesterol esters from low-density lipoprotein in a human acute lymphoblastic leukemia T cell line. 1988 Biochim. Biophys. Acta pmid:3260113
Venkatraman JT and Clandinin MT Ribonucleic acid efflux from isolated mouse liver nuclei is altered by diet and genotypically determined change in nuclear envelope composition. 1988 Biochim. Biophys. Acta pmid:2452656
MacKenzie LW et al. Prostacyclin biosynthesis by cultured human myometrial smooth muscle cells: dependency on arachidonic or linoleic acid in the culture medium. 1988 Am. J. Obstet. Gynecol. pmid:3144917
Wooten MW and Wrenn RW Linoleic acid is a potent activator of protein kinase C type III-alpha isoform in pancreatic acinar cells; its role in amylase secretion. 1988 Biochem. Biophys. Res. Commun. pmid:2454109
Benadé AJ et al. Plasma low density lipoprotein composition in relation to atherosclerosis in nutritionally defined Vervet monkeys. 1988 Atherosclerosis pmid:3145748
Sauer LA and Dauchy RT Identification of linoleic and arachidonic acids as the factors in hyperlipemic blood that increase [3H]thymidine incorporation in hepatoma 7288CTC perfused in situ. 1988 Cancer Res. pmid:3130186
Salafsky B et al. Schistosoma mansoni: analysis of cercarial transformation methods. 1988 Exp. Parasitol. pmid:2458958
Hashimoto A et al. Effect of the dietary alpha-linolenate/linoleate balance on leukotriene production and histamine release in rats. 1988 Prostaglandins pmid:2459732
Bakalova RA et al. [A mechanism of the inhibitory effect of alpha-tocopherol and its synthetic analogs on the oxidation of linoleic acid catalyzed by lipoxygenase from reticulocytes]. 1988 Dokl. Akad. Nauk SSSR pmid:3135162
Slinger AJ and Isaac RE Synthesis of apolar ecdysone esters by ovaries of the cockroach Periplaneta americana. 1988 Gen. Comp. Endocrinol. pmid:3371652
Garg ML et al. Fish oil reduces cholesterol and arachidonic acid content more efficiently in rats fed diets containing low linoleic acid to saturated fatty acid ratios. 1988 Biochim. Biophys. Acta pmid:2844278
Laposata M et al. Icosanoid production can be decreased without alterations in cellular arachidonate content or enzyme activities required for arachidonate release and icosanoid synthesis. 1988 J. Biol. Chem. pmid:2893800
Grant HW et al. Dietary linoleic acid, gastric acid, and prostaglandin secretion. 1988 Gastroenterology pmid:3162220
Schepp W et al. Modulation of rat gastric mucosal prostaglandin E2 release by dietary linoleic acid: effects on gastric acid secretion and stress-induced mucosal damage. 1988 Gastroenterology pmid:3163660
Wright JR et al. Essential fatty acid deficiency prevents multiple low-dose streptozotocin-induced diabetes in CD-1 mice. 1988 Proc. Natl. Acad. Sci. U.S.A. pmid:3045812
Galli C Metabolic aspects of the biological roles of omega 3 fatty acids. 1988 Bibl Nutr Dieta pmid:3060104
Handelman GJ et al. Biopsy method for human adipose with vitamin E and lipid measurements. 1988 Lipids pmid:3172989
Palmblad J and Gyllenhammar H Effect of dietary lipids on immunity and inflammation. Review article. 1988 APMIS pmid:2841953
Rimola A et al. Prostaglandin precursor fatty acids in cirrhosis with ascites: effect of linoleic acid infusion in functional renal failure. 1988 Clin. Sci. pmid:3135142
Staats DA et al. Effects of tocopherol depletion on the regional differences in adrenal microsomal lipid peroxidation and steroid metabolism. 1988 Endocrinology pmid:3135177
Nakagawa Y and Waku K Selective inhibition of free arachidonic acid production in activated alveolar macrophages by calmodulin antagonists. 1988 Biochem. Biophys. Res. Commun. pmid:3142466
Rafael J et al. Effect of dietary linoleic acid and essential fatty acid deficiency on resting metabolism, nonshivering thermogenesis and brown adipose tissue in the rat. 1988 J. Nutr. pmid:3367242
Pschera H et al. The influence of copper intrauterine device on fatty acid composition of cervical mucus lecithin. 1988 Contraception pmid:3168451
Jager FC Vitamin E. 1988 Vet. Rec. pmid:3407122
Asciutti-Moura LS et al. Fatty acid composition of serum lipids and its relation to diet in an elderly institutionalized population. 1988 Am. J. Clin. Nutr. pmid:3421207
Griffiths G et al. Delta 6- and delta 12-desaturase activities and phosphatidic acid formation in microsomal preparations from the developing cotyledons of common borage (Borago officinalis). 1988 Biochem. J. pmid:3421914
Casteels M et al. Inhibition of 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholestanoic acid oxidation and of bile acid secretion in rat liver by fatty acids. 1988 J. Biol. Chem. pmid:3350807
Kato K et al. Studies on scavengers of active oxygen species. 1. Synthesis and biological activity of 2-O-alkylascorbic acids. 1988 J. Med. Chem. pmid:3351858
Mooradian AD et al. Effect of free fatty acids on the bioavailability of plasma testosterone and dihydrotestosterone. 1988 J. Steroid Biochem. pmid:3357342
Simpson LO Unsaturated fatty acids. 1988 N. Z. Med. J. pmid:3357629
Shasby DM et al. Oxidants and conductance of cultured epithelial cell monolayers: inositol phospholipid hydrolysis. 1988 Am. J. Physiol. pmid:3144179
Hoffmann P et al. Investigations on the mechanism of a diminished inotropic isoprenaline effect in isolated rat hearts after high linoleic acid diet. 1988 Biomed. Biochim. Acta pmid:2854732
Das UN Effect of phorbolmyristate acetate on fatty acid uptake and distribution in human promyelocytic leukemia (HL-60) cells in vitro. 1988 Biochem. Biophys. Res. Commun. pmid:3144272
Reynolds CH Inactivation of soybean lipoxygenase by lipoxygenase inhibitors in the presence of 15-hydroperoxyeicosatetraenoic acid. 1988 Biochem. Pharmacol. pmid:3144281
Markov KhM et al. [Effect of dietary linoleic acid on the platelet aggregation, fatty acid composition of platelet phospholipids and synthesis of platelet prostaglandins in rats]. 1988 Jul-Aug Vopr. Med. Khim. pmid:3195130
Ghisolfi J et al. Metabolic utilization of linoleic acid from fat emulsion in infants during total parenteral nutrition. 1988 Jul-Aug JPEN J Parenter Enteral Nutr pmid:3138449
Cotter R et al. Fatty acid profiles in response to soybean oil lipid emulsion infusions in essential fatty acid-deficient miniature swine. 1988 Mar-Apr JPEN J Parenter Enteral Nutr pmid:3129587
Markov KhM and Kucherenko AG [Effect of diets with various contents of linoleic acid on the prostaglandin system in the rat kidney]. 1988 Mar-Apr Vopr. Med. Khim. pmid:3400199
Clark RM Lack of correlation between changes in the concentrations of linoleate and arachidonate in human milk relative to total milk lipid. 1988 Nov-Dec J. Pediatr. Gastroenterol. Nutr. pmid:3143822
Booker ML et al. Effect of dietary cholesterol on phosphatidylcholines and phosphatidylethanolamines in bile and gallbladder mucosa in the prairie dog. 1989 Gastroenterology pmid:2507386
Garcia Zevallos M and Farkas T Manipulation of plasma membrane physical state affects desaturase activity in rat lymphocytes. 1989 Arch. Biochem. Biophys. pmid:2786374
Nanji AA and French SW Dietary linoleic acid is required for development of experimentally induced alcoholic liver injury. 1989 Life Sci. pmid:2915600
Glatz JF et al. Fatty acid composition of serum cholesteryl esters and erythrocyte membranes as indicators of linoleic acid intake in man. 1989 Am. J. Clin. Nutr. pmid:2916448
Bernbäck S et al. Fatty acids generated by gastric lipase promote human milk triacylglycerol digestion by pancreatic colipase-dependent lipase. 1989 Biochim. Biophys. Acta pmid:2917153
Hubbard NE and Erickson KL Effect of dietary linoleic acid level on lodgement, proliferation and survival of mammary tumor metastases. 1989 Cancer Lett. pmid:2920371
Mcgregor L et al. Effects of dietary linoleic acid and gamma linolenic acid on platelets of patients with multiple sclerosis. 1989 Acta Neurol. Scand. pmid:2782038
Kihata M [Effects of exogenous insulin on oxidation of glucose and fatty acid in septic rats]. 1989 Nihon Geka Gakkai Zasshi pmid:2668730
Perez RV et al. Augmentation of donor-specific transfusion and cyclosporine effects with dietary linoleic acid. 1989 Transplantation pmid:2660353
Fairbank J et al. Octadeca-9,11-dienoic acid in cervical intraepithelial neoplasia: a colposcopic study. 1989 Clin. Chim. Acta pmid:2612010
Park JH et al. Effects of dietary linoleic acid on mucosal adaptation after small bowel resection. 1989 Digestion pmid:2612750
Hiramatsu N et al. Effects of dietary pantethine levels on drug-metabolizing system in the liver of rats orally administered varying amounts of autoxidized linoleate. 1989 J. Nutr. Sci. Vitaminol. pmid:2585150
Chanussot B et al. Liver microsomal delta 6 and delta 5 linoleic acid desaturation in female BB rats. 1989 Diabetologia pmid:2591647
Clouet P et al. Pathway of alpha-linolenic acid through the mitochondrial outer membrane in the rat liver and influence on the rate of oxidation. Comparison with linoleic and oleic acids. 1989 Biochem. J. pmid:2597132
Bayorh MA et al. Acute and chronic effects of eicosapentaenoic acid (EPA) on the cardiovascular system. 1989 Res. Commun. Chem. Pathol. Pharmacol. pmid:2558405
Meikle AW et al. Nonesterified fatty acids modulate steroidogenesis in mouse Leydig cells. 1989 Am. J. Physiol. pmid:2558577
Hansen O Characterization of fatty acid interaction with ouabain and vanadate binding to (Na+ + K+)-activated ATPase. 1989 Biochim. Biophys. Acta pmid:2554979
D'Aquino M et al. Vitamin A and glutathione-mediated free radical damage: competing reactions with polyunsaturated fatty acids and vitamin C. 1989 Biochem. Biophys. Res. Commun. pmid:2568114
Hrelia S et al. Age-related changes in linoleate and alpha-linolenate desaturation by rat liver microsomes. 1989 Biochem. Biophys. Res. Commun. pmid:2570573
Levay-Young BK and Nandi S Spermidine is necessary for, but not the only mediator of, linoleic acid-stimulated alpha-casein accumulation in mouse mammary epithelial cells. 1989 Endocrinology pmid:2759031
Berlin E et al. Dietary fat and hormonal effects on erythrocyte membrane fluidity and lipid composition in adult women. 1989 Metab. Clin. Exp. pmid:2761416
Reddy SR et al. Effect of linoleic acid infusion on blood pressure in normotensive and hypertensive rats. 1989 Am. J. Physiol. pmid:2764141
Robertson DA et al. Linoleic acid supplementation, membrane lipids and leucocyte sodium transport in normotensive humans. 1989 J Hum Hypertens pmid:2760909
el Ashry A et al. The effect of dietary linoleic acid on blood pressure and erythrocyte sodium transport. 1989 J Hum Hypertens pmid:2724276
Stein O et al. Modification of cellular fatty acid composition of Hep-G2 cells: effect of antioxidants on cholesterol esterification and secretion. 1989 Biochim. Biophys. Acta pmid:2730885
Reinaud O et al. Oxidative metabolism of linoleic acid by human leukocytes. 1989 Biochem. Biophys. Res. Commun. pmid:2735926
Cunnane SC et al. Essential fatty acid and lipid profiles in plasma and erythrocytes in patients with multiple sclerosis. 1989 Am. J. Clin. Nutr. pmid:2801584
Rose DP and Connolly JM Stimulation of growth of human breast cancer cell lines in culture by linoleic acid. 1989 Biochem. Biophys. Res. Commun. pmid:2803300
Furr HC et al. The effect of dietary fatty acid composition on liver retinyl ester (vitamin A ester) composition in the rat. 1989 J. Nutr. pmid:2703916
Christon R et al. Modification of fluidity and lipid-protein relationships in pig intestinal brush-border membrane by dietary essential fatty acid deficiency. 1989 Biochim. Biophys. Acta pmid:2538158
Chen Q et al. Hydrolysis of triacylglycerol arachidonic and linoleic acid ester bonds by human pancreatic lipase and carboxyl ester lipase. 1989 Biochim. Biophys. Acta pmid:2503032
Hamazaki T et al. Urinary excretion of PGI2/3-M and recent N-6/3 fatty acid intake. 1989 Prostaglandins pmid:2503856
Mohsenin V and Gee JL Oxidation of alpha 1-protease inhibitor: role of lipid peroxidation products. 1989 J. Appl. Physiol. pmid:2787317
Schneider YJ Optimisation of hybridoma cell growth and monoclonal antibody secretion in a chemically defined, serum- and protein-free culture medium. 1989 J. Immunol. Methods pmid:2644356
Watkins BA Influences of biotin deficiency and dietary trans-fatty acids on tissue lipids in chickens. 1989 Br. J. Nutr. pmid:2923859