Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Melanosis D008548 4 associated lipids
Varicocele D014646 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Dermatitis, Phototoxic D017484 4 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Cicatrix, Hypertrophic D017439 4 associated lipids
Biliary Atresia D001656 4 associated lipids
Epilepsy, Temporal Lobe D004833 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Pneumonia, Viral D011024 3 associated lipids
Dermatitis, Toxicodendron D011040 3 associated lipids
Infertility D007246 3 associated lipids
Wasting Syndrome D019282 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Hepatolenticular Degeneration D006527 3 associated lipids
Lactose Intolerance D007787 2 associated lipids
Aneurysm D000783 2 associated lipids
Disease D004194 2 associated lipids
Hypokinesia D018476 2 associated lipids
Darier Disease D007644 2 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
PORTMAN OW and SUGANO M FACTORS INFLUENCING THE LEVEL AND FATTY ACID SPECIFICITY OF THE CHOLESTEROL ESTERIFICATION ACTIVITY IN HUMAN PLASMA. 1964 Arch. Biochem. Biophys. pmid:14236639
SWELL L et al. ROLE OF THE LIVER IN THE METABOLISM OF EXOGENOUS CHOLESTEROL ESTERS. 1964 Arch. Biochem. Biophys. pmid:14236640
WOODALL AN et al. NUTRITION OF SALMONOID FISHES. 13. THE ALPHA-TOCOPHEROL REQUIREMENT OF CHINOOK SALMON. 1964 J. Nutr. pmid:14236910
RAHM JJ and HOLMAN RT STUDIES OF THE METABOLISM OF POLYUNSATURATED ACIDS BY SHORT-TERM EXPERIMENTS. 1964 J. Nutr. pmid:14236913
Lok E et al. Effect of varying the type of fat in a semi-purified AIN-76A diet on cellular proliferation in the mammary gland and intestinal crypts in female Swiss Webster mice. 1992 Carcinogenesis pmid:1423832
JACKSON HD et al. FORMATION OF KETONE BODIES FROM LONG-CHAIN FATTY ACIDS IN RUMEN EPITHELIUM AND LIVER FROM KETOTIC SHEEP. 1964 Arch. Biochem. Biophys. pmid:14240563
BEARE JL and KATES M THE DEPOSITION OF LINOLEIC ACID IN RATS FED CORN OIL. 1964 Can. J. Biochem. pmid:14240731
MOORE JH and WILLIAMS D THE RELATIONSHIP BETWEEN THE LINOLEIC ACID CONTENT OF THE DIET, THE FATTY ACID COMPOSITION OF THE PLASMA PHOSPHOLIPIDS AND THE DEGREE OF AORTIC ATHEROSIS IN EXPERIMENTAL RABBITS. 1964 Br. J. Nutr. pmid:14241591
HOLMES FE AIR-COOLED EXTRACTORS AND THEIR USE IN DETERMINATION OF CHOLESTEROL. 1965 Clin. Chem. pmid:14243897
FELTS JM BIOCHEMISTRY OF THE LUNG. 1964 Health Phys pmid:14244786
ZUCKERMAN AJ and MACDONAID L THE ROLE OF DIETARY CARBOHYDRATES AND INFECTION ON LIVER LIPID AND COLLAGEN. 1964 Br J Exp Pathol pmid:14245158
WEENINK RO and SHORLAND FB THE ISOLATION OF TRANS-3-HEXADECENOIC ACID FROM THE LIPIDS OF RED-CLOVER (TRIFOLIUM PRATENSE) LEAVES. 1964 Biochim. Biophys. Acta pmid:14250500
SEZILLE G and BISERTE G [THE EVOLUTION OF LIPIDS IN THE CHICK EGG IN THE COURSE OF EMBRYONIC DEVELOPMENT]. 1964 C. R. Seances Soc. Biol. Fil. pmid:14250595
NESTEL PJ METABOLISM OF LINOLEATE AND PALMITATE IN PATIENTS WITH HYPERTRIGLYCERIDEMIA AND HEART DISEASE. 1965 Metab. Clin. Exp. pmid:14252339
CHRISTAKIS GJ et al. EFFECT OF A SERUM CHOLESTEROL-LOWERING DIET ON COMPOSITION OF DEPOT FAT IN MAN. 1965 Am. J. Clin. Nutr. pmid:14253897
ZUKEL MC FAT-CONTROLLED DIETS. 1965 Am. J. Clin. Nutr. pmid:14253901
SCHWARTZ S et al. LIPID THROMBOPLASTINS AND MYOCARDIAL INFARCTION. 1965 Am. J. Med. Sci. pmid:14254823
DAYTON S et al. CAN CHANGES IN THE AMERICAN DIET PREVENT CORONARY HEART DISEASE? 1965 J Am Diet Assoc pmid:14256210
MARION JE EFFECT OF AGE AND DIETARY FAT ON THE LIPIDS OF CHICKEN MUSCLE. 1965 J. Nutr. pmid:14257000
PRIVETT OS et al. INFLUENCE OF DIETARY FAT ON TRIGLYCERIDE STRUCTURE IN THE RAT. 1965 J. Nutr. pmid:14259460
SINGLETON WS CHARACTERIZED OILS FOR USE IN INTRAVENOUS FAT EMULSIONS. 1965 Am. J. Clin. Nutr. pmid:14262113
DATEY KK et al. ETHYL LINOLEATE IN EXPERIMENTAL ATHEROGENESIS. 1965 J Assoc Physicians India pmid:14263401
MORIN RJ EFFECTS OF 4-DIMETHYLAMINOAZOBENZENE ON HEPATIC MICROSOMAL PHOSPHOLIPIDS. 1965 Cancer Res. pmid:14264043
STEIN AA et al. FATTY ACID ANALYSIS OF TWO EXPERIMENTAL TRANSMISSIBLE GLIAL TUMORS BY GAS-LIQUID CHROMATOGRAPHY. 1965 Cancer Res. pmid:14264052
STEIN O and STEIN Y FATTY ACID METABOLISM BY IN VIVO LABELED ADIPOSE TISSUE IN ESSENTIAL FATTY ACID DEFICIENT RATS. 1965 Proc. Soc. Exp. Biol. Med. pmid:14264515
SGOUTAS DS and KUMMEROW FA EXPOSURE OF AN ISOTOPE EFFECT OF 3H-LABELED FATTY ACIDS ON SILICA-SILVER NITRATE CHROMATOGRAPHY. 1964 J. Chromatogr. pmid:14265867
STEIN O and STEIN Y METABOLISM IN VITRO OF PALMITIC AND LINOLEIC ACID IN THE HEART AND DIAPHRAGM OF ESSENTIAL FATTY ACID-DEFICIENT RATS. 1964 Biochim. Biophys. Acta pmid:14266247
PRITCHARD ET and NICHOL NE CHOLESTEROL ESTERASE ACTIVITY IN DEVELOPING RAT BRAIN. 1964 Biochim. Biophys. Acta pmid:14266270
OJI K CLINICAL EVALUATION OF LINOLEIC ACID IN THE TREATMENT OF CHRONIC LIVER DISEASES. 1964 Tijdschr Gastroenterol pmid:14272174
pmid:14273071
ALLMANN DW and GIBSON DM FATTY ACID SYNTHESIS DURING EARLY LINOLEIC ACID DEFICIENCY IN THE MOUSE. 1965 J. Lipid Res. pmid:14280473
ALLMANN DW et al. FATTY ACID SYNTHESIS DURING FAT-FREE REFEEDING OF STARVED RATS. 1965 J. Lipid Res. pmid:14280474
DUBIN IN et al. EFFECTS OF ALBUMIN FRACTION AND LINOLEIC ACID ON GROWTH OF MACROPHAGES IN TISSUE CULTURE. 1965 J. Natl. Cancer Inst. pmid:14287281
Terracina L et al. Linoleic acid metabolism in brain cortex of aged rats. 1992 Jul-Aug Ital. J. Biochem. pmid:1428781
MEGHAL SK and NATH MC ACTION OF FATS AND LINOLEIC ACID ON INTESTINAL SYNTHESIS OF THIAMINE IN THIAMINE-DEFICIENT RATS. 1965 Br. J. Nutr. pmid:14290858
DANIEL JC STUDIES ON THE GROWTH OF 5-DAY-OLD RABBIT BLASTOCYSTS IN VITRO. 1965 J Embryol Exp Morphol pmid:14296279
SWELL L et al. ESTERIFICATION OF CHOLESTEROL BY CANINE ADRENAL CELL FRACTIONS. 1965 Proc. Soc. Exp. Biol. Med. pmid:14297887
TANHUANPAEAE E STUDIES ON THE INFLUENCE OF DIETARY METHYL LINOLEATE ON SWINE TISSUE LIPIDS WITH SPECIAL REFERENCE TO NUTRITIONAL MUSCULAR AND LIVE DYSTROPHY. 1965 Acta Vet. Scand. pmid:14298292
GLENN JL and DAM H INFLUENCE OF DIETARY LIPIDS ON THE FATTY ACID COMPOSITION OF NEUTRAL LIPIDS AND PHOSPHATIDES IN CHICK LIVER AND BILE. 1965 J. Nutr. pmid:14300993
KRAUSE RF LIVER LIPIDS IN A CASE OF HYPERVITAMINOSIS A. 1965 Am. J. Clin. Nutr. pmid:14301352
GLENDE EA and CORNATZER WE FATTY ACID COMPOSITION OF RAT LIVER LIPIDS DURING CHOLINE DEFICIENCY. 1965 J. Nutr. pmid:14302120
STOFFEL W and WIESE H [THE BIOSYNTHESIS OF OLEIC-, LINOLEIC- AND GAMMA-LINOLENIC ACID IN PHYCOMYCES BLAKESLEEANUS]. 1965 Hoppe-Seyler's Z. Physiol. Chem. pmid:14309053
Mensink RP et al. Effect of dietary cis and trans fatty acids on serum lipoprotein[a] levels in humans. 1992 J. Lipid Res. pmid:1431574
ANSTALL HB and TRUJILLO JM DETERMINATION OF FREE FATTY ACIDS IN PLASMA BY A COLORIMETRIC PROCEDURE: AN APPRAISAL OF THE METHOD AND COMPARISON WITH OTHER TECHNICS. 1965 Clin. Chem. pmid:14319230
SHAW R THE OCCURRENCE OF GAMMA-LINOLENIC ACID IN FUNGI. 1965 Biochim. Biophys. Acta pmid:14320219
WILLS ED MECHANISMS OF LIPID PEROXIDE FORMATION IN TISSUES. ROLE OF METALS AND HAEMATIN PROTEINS IN THE CATALYSIS OF THE OXIDATION UNSATURATED FATTY ACIDS. 1965 Biochim. Biophys. Acta pmid:14325327
KATO M FATTY ACIDS IN DROSOPHILA MELANOGASTER. I. THE QUALITATIVE ANALYSIS OF UNSATURATED FATTY ACIDS IN DROSOPHILA MELANOGASTER. 1965 Can. J. Biochem. pmid:14325986
YAMAMOTO A et al. INFLUENCE OF DIETARY FATTY ACIDS ON PHOSPHOLIPID FATTY ACID COMPOSITION IN SUBCELLULAR PARTICLES OF RAT LIVER. 1965 J. Lipid Res. pmid:14330770
CAMPBELL AM et al. SERUM LIPIDS OF MEN FED DIETS DIFFERING IN PROTEIN QUALITY AND LINOLEIC ACID CONTENT. 1965 Am. J. Clin. Nutr. pmid:14332349
KOKATNUR MG et al. A RAPID METHOD FOR THE PREPARATION OF PEROXIDES FROM AUTOXIDIZED METHYL ESTERS OF FATTY ACIDS. 1965 Anal. Biochem. pmid:14340025
JAMES AT et al. THE BIOSYNTHESIS OF RICINOLEIC ACID. 1965 Biochem. J. pmid:14340094
SGOUTAS D et al. RADIOHOMOGENEITY OF H3- AND C14-LABELED LINOLEIC ACID IN VIVO. 1965 J. Lipid Res. pmid:14343270
HARRIS RV and JAMES AT CONVERSION OF OLEIC ACID INTO LINOLEIC ACID BY A SUBCELLULAR SYSTEM OF CHLORELLA VULGARIS. 1965 Biochem. J. pmid:14346083
BAKER RW et al. SERUM CHOLESTEROL LINOLEATE LEVELS IN MULTIPLE SCLEROSIS. 1965 J. Neurol. Neurosurg. Psychiatr. pmid:14347622
Kruger M et al. Comparison of the effect of the amount and degree of unsaturation of dietary fat on plasma low density lipoproteins in vervet monkeys. 1992 Lipids pmid:1435092
AAES-JØRGENSEN E et al. The role of fat in the diet of rats. 7. The influence on growth of diets supplemented with raw skim milk, linoleic acid or both; and of raw casein compared with alcohol-extracted casein. 1955 Br. J. Nutr. pmid:14351659
KHAN NA Infrared studies on initiation of the autoxidation of some fatty acid esters with and without light-sensitized chlorophyll, ultraviolet light and lipoxidase. 1955 Biochim. Biophys. Acta pmid:14363243
CHENG AL et al. The effect of fat level of the diet on general nutrition. XV. Comparison of the protective effect of linoleic acid and linolenic acid against multiple sublethal doses of x-irradiation in the rat. 1955 J. Nutr. pmid:14368364
PEIFER JJ et al. Studies on the distribution of lipides in hypercholesteremic rats. I. The effect of feeding palmitate, oleate, linoleate, linolenate, menhaden and tuna oils. 1960 Arch. Biochem. Biophys. pmid:14431396
JAGANNATHAN SN Effect of feeding different fat mixtures providing the same amount of linoleic acid, on serum cholesterol levels in monkeys and liver cholesterol concentration in cholesterol-fed rats. 1962 J. Nutr. pmid:14450883
JAGANNATHAN SN Effect of feeding fat blends of hydrogenated groundnut (peanut) fat and cottonseed oil containing different levels of linoleic acid on serum choles terol levels in monkeys (Macaca radiata) and liver cholesterol concentration in cholesterol-fed rats. 1962 J. Nutr. pmid:14450884
Setty BN et al. 1-Deamino-8 D-arginine vasopressin decreases the production of 13-hydroxyoctadecadienoic acid by endothelial cells. 1992 Thromb. Res. pmid:1448788
Iacazio G Easy access to various natural keto polyunsaturated fatty acids and their corresponding racemic alcohols. 2003 Chem. Phys. Lipids pmid:14499470
Buydens-Branchey L et al. Polyunsaturated fatty acid status and relapse vulnerability in cocaine addicts. 2003 Psychiatry Res pmid:14500111
Raederstorff D and Moser U Influence of an increased intake of linoleic acid on the incorporation of dietary (n-3) fatty acids in phospholipids and on prostanoid synthesis in rat tissues. 1992 Biochim. Biophys. Acta pmid:1450214
Toomey S et al. Regression of pre-established atherosclerosis in the apoE-/- mouse by conjugated linoleic acid. 2003 Biochem. Soc. Trans. pmid:14505483
Teachey MK et al. Interactions of conjugated linoleic acid and lipoic acid on insulin action in the obese Zucker rat. 2003 Metab. Clin. Exp. pmid:14506623
Bas P et al. Fatty acid composition of mixed-rumen bacteria: effect of concentration and type of forage. 2003 J. Dairy Sci. pmid:14507030
Satoh S et al. [Effect of type of dietary fat and ethanol on hepatic leukotriene level in experimental alcoholic liver disease]. 2003 Nihon Arukoru Yakubutsu Igakkai Zasshi pmid:14515744
Byczkowski JZ et al. Some aspects of activation and inhibition of rat brain lipoxygenase. 1992 Int. J. Biochem. pmid:1451903
Brown JM and McIntosh MK Conjugated linoleic acid in humans: regulation of adiposity and insulin sensitivity. 2003 J. Nutr. pmid:14519781
Meerarani P et al. Zinc modulates PPARgamma signaling and activation of porcine endothelial cells. 2003 J. Nutr. pmid:14519784
Peterson DG et al. Diet-induced milk fat depression in dairy cows results in increased trans-10, cis-12 CLA in milk fat and coordinate suppression of mRNA abundance for mammary enzymes involved in milk fat synthesis. 2003 J. Nutr. pmid:14519791
Terpstra AH et al. Dietary conjugated linoleic acids as free fatty acids and triacylglycerols similarly affect body composition and energy balance in mice. 2003 J. Nutr. pmid:14519807
Bassaganya-Riera J et al. Conjugated linoleic acid ameliorates viral infectivity in a pig model of virally induced immunosuppression. 2003 J. Nutr. pmid:14519812
Fang X et al. Microencapsulation of linoleic acid with low- and high-molecular-weight components of soluble soybean polysaccharide and its oxidation process. 2003 Biosci. Biotechnol. Biochem. pmid:14519968
Nagata J et al. Effects of highly purified structured lipids containing medium-chain fatty acids and linoleic acid on lipid profiles in rats. 2003 Biosci. Biotechnol. Biochem. pmid:14519979
Smith MA et al. Heterologous expression of a fatty acid hydroxylase gene in developing seeds of Arabidopsis thaliana. 2003 Planta pmid:14520576
Widstrom RL et al. Fatty acid-binding proteins inhibit hydration of epoxyeicosatrienoic acids by soluble epoxide hydrolase. 2003 Biochemistry pmid:14529287
Fiume MZ Final report on the amended safety assessment of diisopropyl dimer dilinoleate, dicetearyl dimer dilinoleate, diisostearyl dimer dilinoleate, dioctyl dimer dilinoleate, dioctyldodecyl dimer dilinoleate, and ditridecyl dimer dilinoleate. 2003 Int. J. Toxicol. pmid:14555419
Tsao R et al. Antioxidant isoflavones in Osage orange, Maclura pomifera (Raf.) Schneid. 2003 J. Agric. Food Chem. pmid:14558760
Oku K et al. NMR and quantum chemical study on the OH...pi and CH...O interactions between trehalose and unsaturated fatty acids: implication for the mechanism of antioxidant function of trehalose. 2003 J. Am. Chem. Soc. pmid:14558821
Cunnane SC Problems with essential fatty acids: time for a new paradigm? 2003 Prog. Lipid Res. pmid:14559071
O'Hagan S and Menzel A A subchronic 90-day oral rat toxicity study and in vitro genotoxicity studies with a conjugated linoleic acid product. 2003 Food Chem. Toxicol. pmid:14563400
Beeharry N et al. Linoleic acid and antioxidants protect against DNA damage and apoptosis induced by palmitic acid. 2003 Mutat. Res. pmid:14563528
Ruyter B et al. Influence of temperature and high dietary linoleic acid content on esterification, elongation, and desaturation of PUFA in Atlantic salmon hepatocytes. 2003 Lipids pmid:14577662
Dubnov G and Berry EM Omega-6/omega-3 fatty acid ratio: the Israeli paradox. 2003 World Rev Nutr Diet pmid:14579685
Zampelas A et al. Linoleic acid to alpha-linolenic acid ratio. From clinical trials to inflammatory markers of coronary artery disease. 2003 World Rev Nutr Diet pmid:14579686
Hamazaki T and Okuyama H The Japan Society for Lipid Nutrition recommends to reduce the intake of linoleic acid. A review and critique of the scientific evidence. 2003 World Rev Nutr Diet pmid:14579687
Bellini MJ et al. Effect of simvastatin on the uptake and metabolic conversion of palmitic, dihomo-gamma-linoleic and alpha-linolenic acids in A549 cells. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:14580370
Braca A et al. Chemical composition and antioxidant activity of phenolic compounds from wild and cultivated Sclerocarya birrea(Anacardiaceae) leaves. 2003 J. Agric. Food Chem. pmid:14582961
Counet C and Collin S Effect of the number of flavanol units on the antioxidant activity of procyanidin fractions isolated from chocolate. 2003 J. Agric. Food Chem. pmid:14582980
Somoza V et al. Activity-guided identification of a chemopreventive compound in coffee beverage using in vitro and in vivo techniques. 2003 J. Agric. Food Chem. pmid:14582987
Bennett JO et al. Positional effect on protein and oil content and composition of soybeans. 2003 J. Agric. Food Chem. pmid:14582990
Bretillon L et al. Peroxisome proliferator-activated receptor alpha is not the exclusive mediator of the effects of dietary cyclic FA in mice. 2003 Lipids pmid:14584603
Girelli D et al. Red blood cells and platelet membrane fatty acids in non-dialyzed and dialyzed uremics. 1992 Clin. Chim. Acta pmid:1458610
Matsui K et al. Linoleic acid 10-hydroperoxide as an intermediate during formation of 1-octen-3-ol from linoleic acid in Lentinus decadetes. 2003 Biosci. Biotechnol. Biochem. pmid:14586122
Yin D et al. Fenton reagents may not initiate lipid peroxidation in an emulsified linoleic acid model system. 1992 Free Radic. Biol. Med. pmid:1459478
Reis A et al. Detection and characterization by mass spectrometry of radical adducts produced by linoleic acid oxidation. 2003 J. Am. Soc. Mass Spectrom. pmid:14597115
Gülçin I et al. In vitro antioxidant properties of morphine. 2004 Pharmacol. Res. pmid:14597153