Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Retinoblastoma D012175 12 associated lipids
Liposarcoma D008080 1 associated lipids
Hyperlipidemia, Familial Combined D006950 9 associated lipids
Haemophilus Infections D006192 3 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Helicobacter Infections D016481 21 associated lipids
Onchocerciasis D009855 1 associated lipids
Infertility D007246 3 associated lipids
Melanosis D008548 4 associated lipids
Embolism, Fat D004620 4 associated lipids
Dermatitis, Phototoxic D017484 4 associated lipids
Refractive Errors D012030 1 associated lipids
Polycystic Kidney Diseases D007690 12 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Malaria, Cerebral D016779 1 associated lipids
Coronary Restenosis D023903 10 associated lipids
Wounds, Penetrating D014950 10 associated lipids
Hypokinesia D018476 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Letawe C et al. Digital image analysis of the effect of topically applied linoleic acid on acne microcomedones. 1998 Clin. Exp. Dermatol. pmid:9692305
Fungwe TV et al. Fatty acids modulate lecithin:cholesterol acyltransferase secretion independently of effects on triglyceride secretion in primary rat hepatocytes. 1998 J. Nutr. pmid:9687543
Kato M et al. Reactivity of soybean lipoxygenase-1 to linoleic acid entrapped in phosphatidylcholine vesicles. 1998 J. Biochem. pmid:9685717
Kang LT and Vanderhoek JY Mono (S) hydroxy fatty acids: novel ligands for cytosolic actin. 1998 J. Lipid Res. pmid:9684751
Demmelmair H et al. Metabolism of U13C-labeled linoleic acid in lactating women. 1998 J. Lipid Res. pmid:9684741
Kelly ML et al. Effect of intake of pasture on concentrations of conjugated linoleic acid in milk of lactating cows. 1998 J. Dairy Sci. pmid:9684170
Osakabe N et al. The antioxidative substances in cacao liquor. 1998 J. Nutr. Sci. Vitaminol. pmid:9675711
Guarini P et al. Effects of dietary fish oil and soy phosphatidylcholine on neutrophil fatty acid composition, superoxide release, and adhesion. 1998 Inflammation pmid:9675609
Senzaki H et al. Dietary effects of fatty acids on growth and metastasis of KPL-1 human breast cancer cells in vivo and in vitro. 1998 May-Jun Anticancer Res. pmid:9673380
Cesano A et al. Opposite effects of linoleic acid and conjugated linoleic acid on human prostatic cancer in SCID mice. 1998 May-Jun Anticancer Res. pmid:9673351
Pitchumoni S et al. Reoxygenation injury affects isolated islet response to fatty acid stimulation. 1998 Metab. Clin. Exp. pmid:9667226
Zock PL and Katan MB Linoleic acid intake and cancer risk: a review and meta-analysis. 1998 Am. J. Clin. Nutr. pmid:9665108
Erickson KL Is there a relation between dietary linoleic acid and cancer of the breast, colon, or prostate? 1998 Am. J. Clin. Nutr. pmid:9665090
Scimeca JA Toxicological evaluation of dietary conjugated linoleic acid in male Fischer 344 rats. 1998 Food Chem. Toxicol. pmid:9662414
Antonova SI [The dynamics of the secretion of linoleic acid as a component of the lipid classes with milk and their metabolism in the body of cows]. 1998 Apr-Jun Usp Fiziol Nauk pmid:9659686
Ohhashi K et al. Effect of replacing a high linoleate oil with a low linoleate, high alpha-linolenate oil, as compared with supplementing EPA or DHA, on reducing lipid mediator production in rat polymorphonuclear leukocytes. 1998 Biol. Pharm. Bull. pmid:9657037
Yazu K et al. Mechanism of lower oxidizability of eicosapentaenoate than linoleate in aqueous micelles. II. Effect of antioxidants. 1998 Lipids pmid:9655375
Bibus DM and Stitt PA Metabolism of alpha-linolenic acid from flaxseed in dogs. 1998 World Rev Nutr Diet pmid:9648515
Kagan VE et al. Plasma membrane NADH-coenzyme Q0 reductase generates semiquinone radicals and recycles vitamin E homologue in a superoxide-dependent reaction. 1998 FEBS Lett. pmid:9645471
Dailly E et al. Chain-breaking antioxidants and ferriheme-bound drugs are synergistic inhibitors of erythrocyte membrane peroxidation. 1998 Free Radic. Res. pmid:9645396