Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Seizures D012640 87 associated lipids
Nerve Degeneration D009410 53 associated lipids
Birth Weight D001724 23 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Dermatitis D003872 30 associated lipids
Protein-Energy Malnutrition D011502 9 associated lipids
Hypersensitivity, Immediate D006969 14 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Diabetic Angiopathies D003925 20 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Fu J et al. Hypolipidemic activity in Sprague-Dawley rats and constituents of a novel natural vegetable oil from Cornus wilsoniana fruits. 2012 J. Food Sci. pmid:22747885
Wajid NA and Halpern BP Oral cavity discrimination of vapor-phase long-chain 18-carbon fatty acids. 2012 Chem. Senses pmid:22459162
Ménard N et al. Novel surfactants with diglutamic acid polar head group: drug solubilization and toxicity studies. 2012 Pharm. Res. pmid:22451248
Harvey KA et al. Trans fatty acids: induction of a pro-inflammatory phenotype in endothelial cells. 2012 Lipids pmid:22684911
Moodley R et al. Elemental composition and fatty acid profile of the edible fruits of Amatungula (Carissa macrocarpa) and impact of soil quality on chemical characteristics. 2012 Anal. Chim. Acta pmid:22632042
Ruparel S et al. Plasticity of cytochrome P450 isozyme expression in rat trigeminal ganglia neurons during inflammation. 2012 Pain pmid:22633978
Jarret RL and Levy IJ Oil and fatty acid contents in seed of Citrullus lanatus Schrad. 2012 J. Agric. Food Chem. pmid:22540530
Shimomura K et al. Identification of the plant origin of propolis from Jeju Island, Korea, by observation of honeybee behavior and phytochemical analysis. 2012 Biosci. Biotechnol. Biochem. pmid:23132582
Dramane G et al. STIM1 regulates calcium signaling in taste bud cells and preference for fat in mice. 2012 J. Clin. Invest. pmid:22546859
Macaluso F et al. Effect of conjugated linoleic acid on testosterone levels in vitro and in vivo after an acute bout of resistance exercise. 2012 J Strength Cond Res pmid:22614148
Naqvi AZ et al. Dietary fatty acids and peripheral artery disease in adults. 2012 Atherosclerosis pmid:22552117
Banti CN et al. Mixed ligand-silver(I) complexes with anti-inflammatory agents which can bind to lipoxygenase and calf-thymus DNA, modulating their function and inducing apoptosis. 2012 Metallomics pmid:22552402
Joshi S et al. Synthesis, antibacterial activity and mode of action of novel linoleic acid-dipeptide-spermidine conjugates. 2012 Org. Biomol. Chem. pmid:22986997
Dubé E et al. Modulation of fatty acid transport and metabolism by maternal obesity in the human full-term placenta. 2012 Biol. Reprod. pmid:22553224
Perdriau S et al. Selective conversion of polyenes to monoenes by RuCl(3) -catalyzed transfer hydrogenation: the case of cashew nutshell liquid. 2012 ChemSusChem pmid:23060315
O'Donnell-Megaro AM et al. Effect of linoleic acid and dietary vitamin E supplementation on sustained conjugated linoleic acid production in milk fat from dairy cows. 2012 J. Dairy Sci. pmid:23063161
Heinze VM and Actis AB Dietary conjugated linoleic acid and long-chain n-3 fatty acids in mammary and prostate cancer protection: a review. 2012 Int J Food Sci Nutr pmid:21762028
Kurotani K et al. High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. 2012 Nutr Res pmid:23084639
Weiss LA et al. The omega-6 fatty acid linoleic acid is associated with risk of gastroschisis: a novel dietary risk factor. 2012 Am. J. Med. Genet. A pmid:22315197
Sun X et al. Lipid peroxidation and DNA adduct formation in lymphocytes of premenopausal women: Role of estrogen metabolites and fatty acid intake. 2012 Int. J. Cancer pmid:22322480
Zhu X et al. Release property and antioxidant effectiveness of tocopherol-incorporated LDPE/PP blend films. 2012 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:22257167
Tanaka R et al. Prenylated acylphloroglucinol derivatives: isoprenomics-based design, syntheses and antioxidative activities. 2012 Adv. Exp. Med. Biol. pmid:22259110
Raatz SK et al. Total dietary fat and fatty acid content modifies plasma phospholipid fatty acids, desaturase activity indices, and urinary prostaglandin E in women. 2012 Nutr Res pmid:22260857
Gu L et al. Chemical and cellular antioxidant activity of two novel peptides designed based on glutathione structure. 2012 Food Chem. Toxicol. pmid:22940538
Sandoval-Montemayor NE et al. Chemical composition of hexane extract of Citrus aurantifolia and anti-Mycobacterium tuberculosis activity of some of its constituents. 2012 Molecules pmid:22992784
de Batlle J et al. Association between Ω3 and Ω6 fatty acid intakes and serum inflammatory markers in COPD. 2012 J. Nutr. Biochem. pmid:21889886
Koch C et al. Linoleic acid positioning in psi factor producing oxygenase A, a fusion protein with an atypical cytochrome P450 activity. 2012 FEBS J. pmid:21920024
Luévano-Martínez LA et al. A critical tyrosine residue determines the uncoupling protein-like activity of the yeast mitochondrial oxaloacetate carrier. 2012 Biochem. J. pmid:22236206
Jorge AT et al. Schinus terebinthifolius Raddi extract and linoleic acid from Passiflora edulis synergistically decrease melanin synthesis in B16 cells and reconstituted epidermis. 2012 Int J Cosmet Sci pmid:22738140
Manzoor M et al. Variation in minerals, phenolics and antioxidant activity of peel and pulp of different varieties of peach (Prunus persica L.) fruit from Pakistan. 2012 Molecules pmid:22728349
Tao XM et al. Enhanced anticancer activity of gemcitabine coupling with conjugated linoleic acid against human breast cancer in vitro and in vivo. 2012 Eur J Pharm Biopharm pmid:22728546
Zhou YJ et al. Linoleic acid activates GPR40/FFA1 and phospholipase C to increase [Ca2+]i release and insulin secretion in islet beta-cells. 2012 Chin. Med. Sci. J. pmid:22734209
Dundar A et al. Antioxidant properties, chemical composition and nutritional value of Terfezia boudieri (Chatin) from Turkey. 2012 Food Sci Technol Int pmid:22773542
Ogawa N et al. Intestinal fatty acid infusion modulates food preference as well as calorie intake via the vagal nerve and midbrain-hypothalamic neural pathways in rats. 2012 Metab. Clin. Exp. pmid:22445513
Shen J et al. Effect of essential fatty acids on glucose-induced cytotoxicity to retinal vascular endothelial cells. 2012 Lipids Health Dis pmid:22781401
Smink W et al. Linoleic and α-linolenic acid as precursor and inhibitor for the synthesis of long-chain polyunsaturated fatty acids in liver and brain of growing pigs. 2012 Animal pmid:22436184
Zened A et al. In vitro study of dietary factors affecting the biohydrogenation shift from trans-11 to trans-10 fatty acids in the rumen of dairy cows. 2012 Animal pmid:22436225
Liu X et al. Method for screening of bacterial strains biosynthesizing specific conjugated linoleic acid isomers. 2012 J. Agric. Food Chem. pmid:22946615
Eserian JK et al. Effects of polyunsaturated fatty acids on cocaine-conditioned place preference in mice. 2012 Nutr Neurosci pmid:22390908
Fei J et al. ω-6 lipids regulate PPAR turnover via reciprocal switch between PGC-1 alpha and ubiquitination. 2012 Atherosclerosis pmid:22464285
Marei WF et al. Differential effects of linoleic and alpha-linolenic fatty acids on spatial and temporal mitochondrial distribution and activity in bovine oocytes. 2012 Reprod. Fertil. Dev. pmid:22697118
Jarvis MF Cytochrome P450 mediated linoleic acid metabolism in peripheral inflammatory nociception. 2012 Pain pmid:22681878
Passos PP et al. Dopaminergic cell populations of the rat substantia nigra are differentially affected by essential fatty acid dietary restriction over two generations. 2012 J. Chem. Neuroanat. pmid:22687395
He M et al. Effect of dietary fat blend enriched in oleic or linoleic acid and monensin supplementation on dairy cattle performance, milk fatty acid profiles, and milk fat depression. 2012 J. Dairy Sci. pmid:22365227
Castro LF et al. Functional desaturase Fads1 (Δ5) and Fads2 (Δ6) orthologues evolved before the origin of jawed vertebrates. 2012 PLoS ONE pmid:22384110
Li KL et al. Characterization of cumulus expansion-inhibiting factor (CEIF) in goat follicles. 2012 Biol. Reprod. pmid:22402961
Dall'Asta C et al. Role of maize hybrids and their chemical composition in Fusarium infection and fumonisin production. 2012 J. Agric. Food Chem. pmid:22409349
Mulligan CM et al. Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart. 2012 Cardiovasc. Res. pmid:22411972
Gull J et al. Variation in antioxidant attributes at three ripening stages of guava (Psidium guajava L.) fruit from different geographical regions of Pakistan. 2012 Molecules pmid:22418924
Lasa A et al. The combination of resveratrol and CLA does not increase the delipidating effect of each molecule in 3T3-L1 adipocytes. 2011 Sep-Oct Nutr Hosp pmid:22072344
Okui T et al. Cis-9,trans-11-conjugated linoleic acid promotes neuronal differentiation through regulation of Hes6 mRNA and cell cycle in cultured neural stem cells. 2011 Sep-Oct Prostaglandins Leukot. Essent. Fatty Acids pmid:21723718
Mujtaba SF et al. Production of ROS by photosensitized anthracene under sunlight and UV-R at ambient environmental intensities. 2011 Sep-Oct Photochem. Photobiol. pmid:21668866
Ramandi NF et al. Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L. flower. 2011 Nov-Dec J. Food Sci. pmid:22416687
Olszewska MA Variation in the phenolic content and in vitro antioxidant activity of Sorbus aucuparia leaf extracts during vegetation. 2011 Nov-Dec Acta Pol Pharm pmid:22125960
Olszewska MA In vitro antioxidant activity and total phenolic content of the inflorescences, leaves and fruits of Sorbus torminalis (L.) Crantz. 2011 Nov-Dec Acta Pol Pharm pmid:22125961
Kezutyte T et al. Study of tolnaftate release from fatty acids containing ointment and penetration into human skin ex vivo. 2011 Nov-Dec Acta Pol Pharm pmid:22125963
China R et al. In vitro antioxidant activity of different cultivars of banana flower (Musa paradicicus L.) extracts available in India. 2011 Nov-Dec J. Food Sci. pmid:22416691
Permiakova MD and Trufanov VA [Effect of soybean lipoxygenae on baking properties of wheat flour]. 2011 May-Jun Prikl. Biokhim. Mikrobiol. pmid:21790037
Qu WX et al. Analysis of fatty acids in A. szechenyianum Gay. by microwave-assisted extraction and gas chromatography-mass spectrometry. 2011 May-Jun Phytochem Anal pmid:20848395
Lam YY et al. Insulin-stimulated glucose uptake and pathways regulating energy metabolism in skeletal muscle cells: the effects of subcutaneous and visceral fat, and long-chain saturated, n-3 and n-6 polyunsaturated fatty acids. 2011 Jul-Aug Biochim. Biophys. Acta pmid:21570480
de Luis DA et al. Double blind randomized clinical trial controlled by placebo with an alpha linoleic acid and prebiotic enriched cookie on risk cardiovascular factor in obese patients. 2011 Jul-Aug Nutr Hosp pmid:22470031
Aluf Y et al. Alterations in striatal oxidative stress level produced by pharmacological manipulation of dopamine as shown by a novel synthetic marker molecule. 2011 Jul-Aug Neuropharmacology pmid:21414328
Shin D et al. Dietary combination effects of conjugated linoleic acid and flaxseed or fish oil on the concentration of linoleic and arachidonic acid in poultry meat. 2011 Poult. Sci. pmid:21597077
Yepuri G et al. Dietary modulation of body composition and insulin sensitivity during catch-up growth in rats: effects of oils rich in n-6 or n-3 PUFA. 2011 Br. J. Nutr. pmid:21281526
Wang L et al. Acute stimulation of glucagon secretion by linoleic acid results from GPR40 activation and [Ca2+]i increase in pancreatic islet {alpha}-cells. 2011 J. Endocrinol. pmid:21565851
Liu SJ et al. Effect of ruminal pulse dose of polyunsaturated fatty acids on ruminal microbial populations and duodenal flow and milk profiles of fatty acids. 2011 J. Dairy Sci. pmid:21605768
P Wrobel T et al. Imaging of lipids in atherosclerotic lesion in aorta from ApoE/LDLR-/- mice by FT-IR spectroscopy and Hierarchical Cluster Analysis. 2011 Analyst pmid:22007352
Lebold KM et al. Vitamin E deficiency decreases long-chain PUFA in zebrafish (Danio rerio). 2011 J. Nutr. pmid:22013196
Nishioka N et al. Linoleic acid enhances angiogenesis through suppression of angiostatin induced by plasminogen activator inhibitor 1. 2011 Br. J. Cancer pmid:22015554
Alimi H et al. Evaluation of antioxidant and antiulcerogenic activities of Opuntia ficus indica f. inermis flowers extract in rats. 2011 Environ. Toxicol. Pharmacol. pmid:22004960
Strandvik B The omega-6/omega-3 ratio is of importance! 2011 Prostaglandins Leukot. Essent. Fatty Acids pmid:21945460
Espinosa-Neira R et al. Linoleic acid induces an EMT-like process in mammary epithelial cells MCF10A. 2011 Int. J. Biochem. Cell Biol. pmid:21945809
Sousa A et al. Chemical characterization of "alcaparras" stoned table olives from northeast Portugal. 2011 Molecules pmid:22031066
Končić MZ et al. Antiradical, chelating and antioxidant activities of hydroxamic acids and hydroxyureas. 2011 Molecules pmid:21788931
Ramsden CE et al. All PUFAs are not created equal: absence of CHD benefit specific to linoleic acid in randomized controlled trials and prospective observational cohorts. 2011 World Rev Nutr Diet pmid:21865817
Okuyama H et al. New Cholesterol Guidelines for Longevity (2010). 2011 World Rev Nutr Diet pmid:21865826
Legrand P et al. Update of French nutritional recommendations for fatty acids. 2011 World Rev Nutr Diet pmid:21865827
Khan AA et al. Synthesis and characterization of novel PUFA esters exhibiting potential anticancer activities: an in vitro study. 2011 Eur J Med Chem pmid:21868138
Ozcan B et al. Antimicrobial and antioxidant activities of the various extracts of Verbascum pinetorum Boiss. O. Kuntze (Scrophulariaceae). 2011 Eur Rev Med Pharmacol Sci pmid:21845800
Arciniega JC et al. Effects of free fatty acids on meibomian lipid films. 2011 Exp. Eye Res. pmid:21718696
Yang Y et al. Synthesis and antioxidant capacities of hydroxyl derivatives of cinnamoylphenethylamine in protecting DNA and scavenging radicals. 2011 Free Radic. Res. pmid:21128731
Hubert DJ et al. In vitro hepatoprotective and antioxidant activities of crude extract and isolated compounds from Ficus gnaphalocarpa. 2011 Inflammopharmacology pmid:21088994
Jin G et al. Crude lipoxygenase from pig muscle: partial characterization and interactions of temperature, NaCl and pH on its activity. 2011 Meat Sci. pmid:21093161
Du YZ et al. Linoleic acid-grafted chitosan oligosaccharide micelles for intracellular drug delivery and reverse drug resistance of tumor cells. 2011 Int. J. Biol. Macromol. pmid:21093477
Huang YS et al. Eicosadienoic acid differentially modulates production of pro-inflammatory modulators in murine macrophages. 2011 Mol. Cell. Biochem. pmid:21688154
Tuei VC et al. Effects of human serum albumin complexed with free fatty acids on cell viability and insulin secretion in the hamster pancreatic β-cell line HIT-T15. 2011 Life Sci. pmid:21396379
Mihaljević B et al. Linoleic acid peroxidation vs. isomerization: a biomimetic model of free radical reactivity in the presence of thiols. 2011 Org. Biomol. Chem. pmid:21442126
Blum JL et al. Profiling of fatty acids released during calcium-induced mitochondrial permeability transition in isolated rabbit kidney cortex mitochondria. 2011 Toxicol In Vitro pmid:21443943
Conforti F et al. Correlation between environmental factors, chemical composition, and antioxidative properties of caper species growing wild in Calabria (South Italy). 2011 Chem. Biodivers. pmid:21404435
Serratosa MP et al. Changes in hydrophilic and lipophilic antioxidant activity in relation to their phenolic composition during the chamber drying of red grapes at a controlled temperature. 2011 J. Agric. Food Chem. pmid:21319807
Parra-Cabrera S et al. Dietary intakes of polyunsaturated fatty acids among pregnant Mexican women. 2011 Matern Child Nutr pmid:21410881
Konkel A and Schunck WH Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids. 2011 Biochim. Biophys. Acta pmid:20869469
Liou AP et al. The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin. 2011 Gastroenterology pmid:20955703
Perona JS et al. Olive oil phenols modulate the triacylglycerol molecular species of human very low-density lipoprotein. A randomized, crossover, controlled trial. 2011 Metab. Clin. Exp. pmid:20934731
Mariutto M et al. The elicitation of a systemic resistance by Pseudomonas putida BTP1 in tomato involves the stimulation of two lipoxygenase isoforms. 2011 BMC Plant Biol. pmid:21294872
Pan Z et al. Effects of linoleate on cell viability and lipid metabolic homeostasis in goose primary hepatocytes. 2011 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:21295151
Tsubura A et al. Anticancer effects of garlic and garlic-derived compounds for breast cancer control. 2011 Anticancer Agents Med Chem pmid:21269259
Chohany LE et al. Cationic substrates of soybean lipoxygenase-1. 2011 Bioorg. Chem. pmid:21257189
White HM et al. Differential regulation of bovine pyruvate carboxylase promoters by fatty acids and peroxisome proliferator-activated receptor-α agonist. 2011 J. Dairy Sci. pmid:21700028
Turk HF et al. Linoleic acid and butyrate synergize to increase Bcl-2 levels in colonocytes. 2011 Int. J. Cancer pmid:20232381