Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Facial Nerve Diseases D005155 1 associated lipids
Child Nutrition Disorders D015362 1 associated lipids
Refeeding Syndrome D055677 1 associated lipids
Pellagra D010383 1 associated lipids
Refractive Errors D012030 1 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Onchocerciasis D009855 1 associated lipids
Malaria, Cerebral D016779 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Sasaki T et al. Effects of dietary docosahexaenoic acid on surface molecules involved in T cell proliferation. 1999 Biochim. Biophys. Acta pmid:9989281
Zhou L and Nilsson A Fasting increases tissue uptake and interconversion of plasma unesterified linoleic acid in guinea pigs. 1999 Biochim. Biophys. Acta pmid:9989279
Rao MS et al. Yield, protein, and oil quality of soybean genotypes selected for tofu production. 1998 Plant Foods Hum Nutr pmid:9950085
Black PN The prevalence of allergic disease and linoleic acid in the diet. 1999 J. Allergy Clin. Immunol. pmid:9949330
Toborek M and Hennig B The role of linoleic acid in endothelial cell gene expression. Relationship to atherosclerosis. 1998 Subcell. Biochem. pmid:9932524
Chyb S et al. Polyunsaturated fatty acids activate the Drosophila light-sensitive channels TRP and TRPL. 1999 Nature pmid:9930700
Began G et al. Inhibition of lipoxygenase 1 by phosphatidylcholine micelles-bound curcumin. 1998 Lipids pmid:9930409
Kalivianakis M et al. Fat malabsorption in cystic fibrosis patients receiving enzyme replacement therapy is due to impaired intestinal uptake of long-chain fatty acids. 1999 Am. J. Clin. Nutr. pmid:9925134
Natella F et al. Oxidative modification of human low-density lipoprotein by horseradish peroxidase in the absence of hydrogen peroxide. 1998 Free Radic. Res. pmid:9925035
Allman-Farinelli MA et al. Comparison of the effects of two low fat diets with different alpha-linolenic:linoleic acid ratios on coagulation and fibrinolysis. 1999 Atherosclerosis pmid:9920517
Pohl CH et al. Oxylipin formation in fungi: biotransformation of arachidonic acid to 3-hydroxy-5,8-tetradecadienoic acid by Mucor genevensis. 1998 Biochem. Biophys. Res. Commun. pmid:9918790
Satory DL and Smith SB Conjugated linoleic acid inhibits proliferation but stimulates lipid filling of murine 3T3-L1 preadipocytes. 1999 J. Nutr. pmid:9915881
Hayek MG et al. Dietary conjugated linoleic acid influences the immune response of young and old C57BL/6NCrlBR mice. 1999 J. Nutr. pmid:9915872
Mahfouz MM and Kummerow FA Hydrogenated fat high in trans monoenes with an adequate level of linoleic acid has no effect on prostaglandin synthesis in rats. 1999 J. Nutr. pmid:9915870
O'Donnell VB et al. Nitration of unsaturated fatty acids by nitric oxide-derived reactive nitrogen species peroxynitrite, nitrous acid, nitrogen dioxide, and nitronium ion. 1999 Chem. Res. Toxicol. pmid:9894022
Hennig B et al. Linoleic acid amplifies polychlorinated biphenyl-mediated dysfunction of endothelial cells. 1999 J. Biochem. Mol. Toxicol. pmid:9890193
Cook ME Nutritional effects on vaccination. 1999 Adv Vet Med pmid:9890009
Tsimikas S et al. LDL isolated from Greek subjects on a typical diet or from American subjects on an oleate-supplemented diet induces less monocyte chemotaxis and adhesion when exposed to oxidative stress. 1999 Arterioscler. Thromb. Vasc. Biol. pmid:9888874
Matsuba S et al. Effect of dietary linoleate/alpha-linolenate balance on experimentally induced gastric injury in rats. 1998 Prostaglandins Leukot. Essent. Fatty Acids pmid:9888206
Akeo K and Hiramitsu T Changes in lipid peroxide level in retinal pigment epithelial cells in vitro upon addition of linoleic acids or linoleic acid hydroperoxides under varying concentrations of oxygen. 1998 Pigment Cell Res. pmid:9877104