Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Gastroschisis D020139 1 associated lipids
Fat Necrosis D005218 1 associated lipids
Facial Nerve Diseases D005155 1 associated lipids
Child Nutrition Disorders D015362 1 associated lipids
Refeeding Syndrome D055677 1 associated lipids
Pellagra D010383 1 associated lipids
Refractive Errors D012030 1 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Martin JC et al. Effects of conjugated linoleic acid isomers on lipid-metabolizing enzymes in male rats. 2000 Lipids pmid:10695929
Delmas-Beauvieux MC et al. Liposomes as fatty acids carriers in isolated rat liver: effect on energy metabolism and on isolated mitochondria activity. 2000 MAGMA pmid:10697225
Shimada A et al. Phytotoxicity of indole-3-acetic acid produced by the fungus, Pythium aphanidermatum. 2000 Biosci. Biotechnol. Biochem. pmid:10705467
Kitts DD et al. Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone. 1999 Mol. Cell. Biochem. pmid:10705999
Takahashi N Antioxidant properties of N-(4-hydroxyphenyl)retinamide (fenretinide). 2000 Biol. Pharm. Bull. pmid:10706389
Cox JE et al. Suppression of food intake, body weight, and body fat by jejunal fatty acid infusions. 2000 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:10712279
Chavali SR and Forse RA Decreased production of interleukin-6 and prostaglandin E2 associated with inhibition of delta-5 desaturation of omega6 fatty acids in mice fed safflower oil diets supplemented with sesamol. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10718106
Baron CP et al. Peroxidation of linoleate at physiological pH: hemichrome formation by substrate binding protects against metmyoglobin activation by hydrogen peroxide. 2000 Free Radic. Biol. Med. pmid:10719236
Adeyeye EI et al. Fatty acid composition of six varieties of dehulled African yam bean (Sphenostylis stenocarpa) flour. 1999 Int J Food Sci Nutr pmid:10719567
Fidler N et al. Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women. 1999 Ann. Nutr. Metab. pmid:10725767
Adam O Linoleic acid - the fall of an angel? 1999 Ann. Nutr. Metab. pmid:10725772
Draper AJ and Hammock BD Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase. 2000 Arch. Biochem. Biophys. pmid:10729206
Kemp B et al. Influence of linoleic/linolenic acid ratio in the diet of periparturient cattle on plasma concentrations of PGF2 alpha metabolite and placental expulsion rate. 1998 Theriogenology pmid:10732036
Hochi S et al. Effect of linoleic acid-albumin in the culture medium on freezing sensitivity of in vitro-produced bovine morulae. 1999 Theriogenology pmid:10734383
Clemmesen JO et al. Plasma phospholipid fatty acid pattern in severe liver disease. 2000 J. Hepatol. pmid:10735619
Hudson JA et al. Identification and enumeration of oleic acid and linoleic acid hydrating bacteria in the rumen of sheep and cows. 2000 J. Appl. Microbiol. pmid:10735997
Larqué E et al. Dietary trans fatty acids affect the essential fatty-acid concentration of rat milk. 2000 J. Nutr. pmid:10736340
Whalen MM et al. Lysophosphatidylcholine and arachidonic acid are required in the cytotoxic response of human natural killer cells to tumor target cells. 1999 Cell. Physiol. Biochem. pmid:10749996
Garcia HS et al. Interesterification (acidolysis) of butterfat with conjugated linoleic acid in a batch reactor. 2000 J. Dairy Sci. pmid:10750090
Rubbo H et al. Nitric oxide reaction with lipid peroxyl radicals spares alpha-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/alpha-tocopherol than alpha-tocopherol/ascorbate. 2000 J. Biol. Chem. pmid:10753874