Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Onchocerciasis D009855 1 associated lipids
Malaria, Cerebral D016779 1 associated lipids
Liposarcoma D008080 1 associated lipids
Gastroschisis D020139 1 associated lipids
Fat Necrosis D005218 1 associated lipids
Facial Nerve Diseases D005155 1 associated lipids
Child Nutrition Disorders D015362 1 associated lipids
Refeeding Syndrome D055677 1 associated lipids
Pellagra D010383 1 associated lipids
Refractive Errors D012030 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Howlett NG and Avery SV Induction of lipid peroxidation during heavy metal stress in Saccharomyces cerevisiae and influence of plasma membrane fatty acid unsaturation. 1997 Appl. Environ. Microbiol. pmid:9251184
Parmentier HK et al. Dietary unsaturated fatty acids affect antibody responses and growth of chickens divergently selected for humoral responses to sheep red blood cells. 1997 Poult. Sci. pmid:9251147
Bosca F et al. Photophysical and photochemical characterization of a photosensitizing drug: a combined steady state photolysis and laser flash photolysis study on carprofen. 1997 Chem. Res. Toxicol. pmid:9250417
Thomson AB et al. Nutrient uptake into undifferentiated and differentiated HT-29 cells in culture. 1997 Can. J. Physiol. Pharmacol. pmid:9250367
Hannah JS et al. High fat, high cholesterol diets alter low density lipoprotein size and binding affinity in monkeys. 1997 Atherosclerosis pmid:9247355
Lanson M et al. Supplementation of MCF-7 cells with essential fatty acids induces the activation of protein kinase C in response to IGF-1. 1997 J Lipid Mediat Cell Signal pmid:9246607
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Quoc KP and Dubacq JP Effect of growth temperature on the biosynthesis of eukaryotic lipid molecular species by the cyanobacterium Spirulina platensis. 1997 Biochim. Biophys. Acta pmid:9219908
Jira W et al. Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis. 1997 Chem. Phys. Lipids pmid:9219348
Durgam VR and Fernandes G The growth inhibitory effect of conjugated linoleic acid on MCF-7 cells is related to estrogen response system. 1997 Cancer Lett. pmid:9215854
Usha S et al. Mitogenic stimulation of primary cultures of lung epithelial cells by linoleic acid. 1996 Biochem. Cell Biol. pmid:9213439
Stein CA Controversies in the cellular pharmacology of oligodeoxynucleotides. 1997 Antisense Nucleic Acid Drug Dev. pmid:9212912
Nicolosi RJ et al. Dietary conjugated linoleic acid reduces plasma lipoproteins and early aortic atherosclerosis in hypercholesterolemic hamsters. 1997 Artery pmid:9209699
Yehuda S et al. Essential fatty acid preparation improves biochemical and cognitive functions in experimental allergic encephalomyelitis rats. 1997 Eur. J. Pharmacol. pmid:9203563
Miura K et al. The effects of unsaturated fatty acids, oxidizing agents and Michael reaction acceptors on the induction of N-ethylmaleimide reductase in Escherichia coli: possible application for drug design of chemoprotectors. 1997 Methods Find Exp Clin Pharmacol pmid:9203161
Schut HA et al. DNA adducts of heterocyclic amines: formation, removal and inhibition by dietary components. 1997 Mutat. Res. pmid:9202755
Sauer LA et al. Dietary linoleic acid intake controls the arterial blood plasma concentration and the rates of growth and linoleic acid uptake and metabolism in hepatoma 7288CTC in Buffalo rats. 1997 J. Nutr. pmid:9202100
Petrek JA et al. Fatty acid composition of adipose tissue, an indication of dietary fatty acids, and breast cancer prognosis. 1997 J. Clin. Oncol. pmid:9193329
Sharpe M et al. Ligation, inhibition, and activation of cytochrome c oxidase by fatty acids. 1997 Biochem. Cell Biol. pmid:9192076