Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Onchocerciasis D009855 1 associated lipids
Malaria, Cerebral D016779 1 associated lipids
Liposarcoma D008080 1 associated lipids
Gastroschisis D020139 1 associated lipids
Fat Necrosis D005218 1 associated lipids
Facial Nerve Diseases D005155 1 associated lipids
Child Nutrition Disorders D015362 1 associated lipids
Refeeding Syndrome D055677 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Chew BP et al. Effects of conjugated dienoic derivatives of linoleic acid and beta-carotene in modulating lymphocyte and macrophage function. 1997 Mar-Apr Anticancer Res. pmid:9137456
Wong MW et al. Effects of dietary conjugated linoleic acid on lymphocyte function and growth of mammary tumors in mice. 1997 Mar-Apr Anticancer Res. pmid:9137439
Visonneau S et al. Conjugated linoleic acid suppresses the growth of human breast adenocarcinoma cells in SCID mice. 1997 Mar-Apr Anticancer Res. pmid:9137436
Bourre JM et al. Possible role of the choroid plexus in the supply of brain tissue with polyunsaturated fatty acids. 1997 Neurosci. Lett. pmid:9132678
Schneider C et al. A fatty acid alpha-ketol, a product of the plant lipoxygenase pathway, is oxidized to 3(Z)-dodecendioic acid by a bacterial monooxygenase. 1997 Biochem. Biophys. Res. Commun. pmid:9125182
Ip C and Scimeca JA Conjugated linoleic acid and linoleic acid are distinctive modulators of mammary carcinogenesis. 1997 Nutr Cancer pmid:9121939
Goldreich D et al. The effect of retinol and retinoic acids on lipoxygenase activity. 1997 Int J Vitam Nutr Res pmid:9119612
Fukushima M et al. Comparative hypocholesterolemic effects of capybara (Hydrochoerus hydrochaeris dabbenei) oil, horse oil, and sardine oil in cholesterol-fed rats. 1997 Lipids pmid:9113627
Ip C et al. Retention of conjugated linoleic acid in the mammary gland is associated with tumor inhibition during the post-initiation phase of carcinogenesis. 1997 Carcinogenesis pmid:9111211
Nieuwenhuizen WF et al. Lipoxygenase is irreversibly inactivated by the hydroperoxides formed from the enynoic analogues of linoleic acid. 1997 Biochemistry pmid:9109655
Griffiths G et al. Effect of n-6 polyunsaturated fatty acids on growth and lipid composition of neoplastic and non-neoplastic canine prostate epithelial cell cultures. 1997 Prostate pmid:9108883
Nishizaki T et al. Short-term depression and long-term enhancement of ACh-gated channel currents induced by linoleic and linolenic acid. 1997 Brain Res. pmid:9099812
Hayes KC The linoleic acid content of test diets must be carefully monitored in cholesterol studies. 1997 Am. J. Clin. Nutr. pmid:9094899
Ikeda I et al. Effect of dietary linoleic, alpha-linolenic and arachidonic acids on lipid metabolism, tissue fatty acid composition and eicosanoid production in rats. 1996 J. Nutr. Sci. Vitaminol. pmid:9089480
Yamaki T et al. Acute and reversible fatty metamorphosis of cultured rat hepatocytes. 1997 Feb-Mar Pathol. Int. pmid:9088028
Iwase H et al. Formation of leukotoxin (9,10-epoxy-12-octadecenoic acid) during the autoxidation of phospholipids promoted by hemoproteins. 1997 Biochim. Biophys. Acta pmid:9084498
Schneider C et al. Analysis of lipoxygenase-derived fatty acid hydroperoxides by electrospray ionization tandem mass spectrometry. 1997 Lipids pmid:9076671
Barclay LR et al. Photo-initiated peroxidation of lipids in micelles by azaaromatics. 1997 Lipids pmid:9076660
Belury MA and Kempa-Steczko A Conjugated linoleic acid modulates hepatic lipid composition in mice. 1997 Lipids pmid:9075211
Iwase H et al. Effect of monochlorohydrins of linoleic acid on guinea-pig cardiac papillary muscles. 1997 Biochem. Biophys. Res. Commun. pmid:9070266