Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Refeeding Syndrome D055677 1 associated lipids
Acute Coronary Syndrome D054058 11 associated lipids
Mucositis D052016 7 associated lipids
Renal Insufficiency, Chronic D051436 9 associated lipids
Atherosclerosis D050197 85 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Coronary Restenosis D023903 10 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

Download all related citations
Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Dubnov G and Berry EM Omega-6/omega-3 fatty acid ratio: the Israeli paradox. 2003 World Rev Nutr Diet pmid:14579685
Zampelas A et al. Linoleic acid to alpha-linolenic acid ratio. From clinical trials to inflammatory markers of coronary artery disease. 2003 World Rev Nutr Diet pmid:14579686
Hamazaki T and Okuyama H The Japan Society for Lipid Nutrition recommends to reduce the intake of linoleic acid. A review and critique of the scientific evidence. 2003 World Rev Nutr Diet pmid:14579687
Ramsden CE et al. All PUFAs are not created equal: absence of CHD benefit specific to linoleic acid in randomized controlled trials and prospective observational cohorts. 2011 World Rev Nutr Diet pmid:21865817
Okuyama H et al. New Cholesterol Guidelines for Longevity (2010). 2011 World Rev Nutr Diet pmid:21865826
Watkins BA et al. Designed eggs containing conjugated linoleic acids and omega-3 polyunsaturated fatty acids. 2001 World Rev Nutr Diet pmid:11545041
Legrand P et al. Update of French nutritional recommendations for fatty acids. 2011 World Rev Nutr Diet pmid:21865827
Holman RT Highpoints in an affair with polyunsaturated fatty acids. 1991 World Rev Nutr Diet pmid:2053355
Bibus DM and Stitt PA Metabolism of alpha-linolenic acid from flaxseed in dogs. 1998 World Rev Nutr Diet pmid:9648515
Okuyama H et al. Why isn't the causal relationship between linoleic acid and mortalities from coronary heart disease and stroke revealed by clinical studies? 2007 World Rev Nutr Diet pmid:17167283
Okuyama H et al. Mechanisms by which dietary fats affect coronary heart disease mortality. 2007 World Rev Nutr Diet pmid:17167284
Okuyama H et al. Cancers common in the USA are stimulated by omega 6 fatty acids and large amounts of animal fats, but suppressed by omega 3 fatty acids and cholesterol. 2007 World Rev Nutr Diet pmid:17167285
Demmelmair H et al. Polyunsaturated fatty acid metabolism during lactation. 2001 World Rev Nutr Diet pmid:11935954
Sugano M Isomeric fatty acids: their physiological significance and health implications. 2001 World Rev Nutr Diet pmid:11935963
Cardoso CR et al. Influence of topical administration of n-3 and n-6 essential and n-9 nonessential fatty acids on the healing of cutaneous wounds. 2004 Mar-Apr Wound Repair Regen pmid:15086775
Byczkowski JZ and Kulkarni AP Linoleate-dependent co-oxygenation of benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol by rat cytosolic lipoxygenase. 1992 Xenobiotica pmid:1413876
Nakagawa Y [Metabolism and biological function of cardiolipin]. 2013 Yakugaku Zasshi pmid:23649397
Otsuka H et al. [Studies on anti-inflammatory agents. IV. Anti-inflammatory constituents from roots of Panax ginseng C.A. Meyer (author's transl)]. 1981 Yakugaku Zasshi pmid:7338798
Osaki Y et al. [Antimutagenic and bactericidal substances in the fruit body of a Basidiomycete Agaricus blazei, Jun-17]. 1994 Yakugaku Zasshi pmid:8014843
Yamamoto K et al. [Antimutagenic substances in the Armeniacae semen and Persicae semen]. 1992 Yakugaku Zasshi pmid:1294719
Toda S et al. [Inhibitory effects of methanol extracts of crude drugs on the air oxidation of linoleic acid]. 1984 Yakugaku Zasshi pmid:6491877
Fujii M Pathogenesis of Diet-induced Atopic Dermatitis in Hairless Mice. 2017 Yakugaku Zasshi pmid:28049895
Okuyama H [Need to change the direction of cholesterol-related medication--a problem of great urgency]. 2005 Yakugaku Zasshi pmid:16272805
Wang SC et al. [Analysis of supercritical fluid extracts of Radix caulophylli with gas chromatography-mass spectrometry]. 2007 Yao Xue Xue Bao pmid:17703777
Bian RL et al. [Antianaphylactic components of Asarum forbsii Maxin]. 1990 Yao Xue Xue Bao pmid:2099089
Zhao CX et al. [Chemical components in essential oils from tender branches and leaves of Rhododendron]. 2005 Yao Xue Xue Bao pmid:16342692
He J et al. Correlation of polyunsaturated fatty acids with the cold adaptation of Rhodotorula glutinis. 2015 Yeast pmid:26284451
Yazawa H et al. Production of polyunsaturated fatty acids in yeast Saccharomyces cerevisiae and its relation to alkaline pH tolerance. 2009 Yeast pmid:19243079
Kainou K et al. Isolation of Delta12 and omega3-fatty acid desaturase genes from the yeast Kluyveromyces lactis and their heterologous expression to produce linoleic and alpha-linolenic acids in Saccharomyces cerevisiae. 2006 Yeast pmid:16823888
Tang KH et al. [Oil content of Pyracantha seeds and its relations to soil nutrients in northwestern Hunan Province]. 2007 Ying Yong Sheng Tai Xue Bao pmid:17974264
Reuter W and Heybey U [Dietary fat analysis--a contribution to the problem of nutrition and aging]. 1984 May-Jun Z Alternsforsch pmid:6087576
Ries W et al. Selected metabolic results of the Leipzig gerontological longitudinal study. 1983 Mar-Apr Z Alternsforsch pmid:6868654
WEBER F et al. [VITAMIN E REQUIREMENT IN RELATION TO LINOLEIC ACID FEEDING]. 1964 Z Ernahrungswiss pmid:14163398
Rosenquist A and Hølmer G Nutritional value of micro-encapsulated fish oils in rats. 1996 Z Ernahrungswiss pmid:8766891
Adam O et al. [The effect of linoleic acid intake on its concentration and resultant products in individual plasma lipids in humans]. 1985 Z Ernahrungswiss pmid:4096032
Stroh S and Elmadfa I [In vitro studies of the effect of different mixture proportions of omega-3 and omega-6 fatty acids on thrombocyte aggregation and thromboxane synthesis in human thrombocytes]. 1991 Z Ernahrungswiss pmid:1763556
Kirchgessner M and Müller HL [The effect of palmitic, oleic and linoleic acids on thermogenesis in the model experiment in sows]. 1993 Z Ernahrungswiss pmid:8379216
Gere A Decrease in essential fatty acid content of edible fats during the frying process. 1982 Z Ernahrungswiss pmid:6293212
SZIRMAI E [EXPERIMENTAL STUDIES ON A NEW LINOLEIC ACID-MAGNESIUM THEOPHYLLINE SALT, MAPHYLINOL]. 1963 Z Gesamte Inn Med pmid:14102626
Köhler VH et al. [Results of a long-term study of arteriosclerotic circulatory disorders with polyene fatty acid therapy]. 1986 Z Gesamte Inn Med pmid:2871668
Singer P et al. [Clinical aspects of typical changes in carbohydrate and lipid metabolism in essential hypertension]. 1982 Z Gesamte Inn Med pmid:6750938
Grosch W and Laskawy G [Contribution of linoleic acid to the bitter taste of poppy seeds (Papaver somniferum)]. 1984 Z Lebensm Unters Forsch pmid:6720091
Truchetet E et al. [Skin changes, pathophysiology and therapy in deficiency of essential fatty acids]. 1988 Z. Hautkr. pmid:3291438
Wehrmann W et al. [Clinical and immune-modulating effects of the treatment with unsaturated fatty acids in atopic dermatitis]. 1987 Z. Hautkr. pmid:2831674
Jayaprakasha GK and Rao LJ Phenolic constituents from the lichen Parmotrema stuppeum (Nyl.) Hale and their antioxidant activity. 2000 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:11204179
Kajiwara T et al. Fatty acid oxidizing activity in a red marine alga, Porphyra sp. 2000 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:11204194
Colla LM et al. Fatty acids profile of Spirulina platensis grown under different temperatures and nitrogen concentrations. 2004 Jan-Feb Z. Naturforsch., C, J. Biosci. pmid:15018053
Matthaus B et al. Some rape/canola seed oils: fatty acid composition and tocopherols. 2016 Z. Naturforsch., C, J. Biosci. pmid:27023318
Nicholson T and Omer SA The application of cumulative sum analysis to the investigation of reticulum motility in ruminant animals. 1983 Zentralbl Veterinarmed A pmid:6318476
Xin HL et al. [Alpha-linolenic acid and linoleic acid in extract of Portulaca oleracea L. determined by high-performance liquid chromatography]. 2008 Zhong Xi Yi Jie He Xue Bao pmid:18990345
Li TL et al. [Study on the chemical constituents of Humulus scandens]. 2010 Zhong Yao Cai pmid:20518305
Li GY et al. [Studies on chemistry component and the biological activity of petroleum ether extraction from pre-and post-processed of Cornus officinalis]. 2010 Zhong Yao Cai pmid:20575409
Zhou YJ et al. [Studies on the antioxidant activities of leaves from Senecio argunensis]. 2008 Zhong Yao Cai pmid:19180957
Wang T et al. [Study on the chemical constituents of Heterosmilax japonica]. 2007 Zhong Yao Cai pmid:18236752
Lei H et al. [Supercritical CO2 extraction of fatty oils from bee pollen and its GC-MS analysis]. 2004 Zhong Yao Cai pmid:15272780
Lan M et al. [GC-MS analysis of chemical components in seeds oil from Croton tiglium]. 2012 Zhong Yao Cai pmid:23252276
Zhang X et al. [Supercritical-CO2 fluid extraction of the fatty oil in Terminalia chebula and GC-MS analysis]. 1997 Zhong Yao Cai pmid:12572426
Yuan Y et al. [Chemical constituents of Girardinia palmata ssp ciliata]. 1999 Zhong Yao Cai pmid:12575105
Yang D et al. [Study on lipids and other volatile constituents in Pheretima aspergillum]. 2000 Zhong Yao Cai pmid:12575114
Huang F et al. [Studies on the supercritical CO2 fluid extraction and separation of psoralen, isopsoralen and fatty oils from Psoralea corylifolia]. 2000 Zhong Yao Cai pmid:12575152
Ren S et al. [Analysis of chemical constituents of volatile oil in Armeniaca mume Sieb from different habitats by gas chromatography-mass spectrometry]. 2004 Zhong Yao Cai pmid:15179782
Zhang B et al. [Studies on the chemical constituents of the root and rhizoma of Ligusticum jeholense]. 2009 Zhong Yao Cai pmid:19771843
Jiang X et al. [Studies on chemical constituents of Valeriana officinalis]. 2007 Zhong Yao Cai pmid:18323205
Liu Y et al. [Chemical constituents analysis on anticonvulsive effect of three extracts from radix bupleuri]. 2002 Zhong Yao Cai pmid:12451973
Ding CH et al. [Extraction of fatty constituents from Tabanus bivittatus and their analysis by GC-MS]. 2013 Zhong Yao Cai pmid:23901639
Zheng XB et al. [Analysis of lipid compounds of high-yielded rhizoma pinelliae growing in the west of Hubei province by gas chromatography-mass spectrometry]. 2007 Zhong Yao Cai pmid:17918435
Yuan Y et al. [Study on fat-soluble components in different parts of miao ethnomedicine Pileostegia viburnoides by the herbal blitzkrieg extractor]. 2011 Zhong Yao Cai pmid:22500427
Liang ZF et al. [GC-MS analysis of the liposoluble components from fruits of Harrisonia perforata]. 2009 Zhong Yao Cai pmid:20218293
Tang H et al. [Analysis of fatty acids in leaves of Loropetalum chinense and L. chinense var. rubrum by GC-MS]. 2011 Zhong Yao Cai pmid:22372144
He YL et al. [Effect of peroxisome proliferator-activated receptors activators on plasminogen activator inhibitor-1 expression in HepG-2 cells]. 2003 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:21189605
Chen J et al. [Mechanism of linoleic acid on the expression of plasminogen activator inhibitor type-1 in HepG2 cells]. 2008 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:21141508
Li J et al. [Extraction and comparison of volatile oil components from water caltrop and kernel by supercritical carbon dioxide extraction]. 2011 Zhongguo Zhong Yao Za Zhi pmid:22032133
Gu YX et al. [Antioxidant activity of natural and cultured Cordyceps sp]. 2007 Zhongguo Zhong Yao Za Zhi pmid:17672334
Wang J and Zhang Y [Effect of the long chain polyunsaturated fatty acids levels in mothers on fetuses]. 1998 Zhonghua Fu Chan Ke Za Zhi pmid:10806659
Li KC et al. [A preliminary study of the inhibitive efficacy of iodized linoleic acid and its fluorodeoxyuridine ester in hepatocellular cancer]. 2013 Zhonghua Gan Zang Bing Za Zhi pmid:24025140
Ye P et al. [An exploratory study on mechanism of PPARalpha activators-induced plasminogen activator inhibitor-1 expression in HepG-2 cells]. 2004 Zhonghua Nei Ke Za Zhi pmid:15631825
Yang YM et al. [The effects of conjugated linoleic acid on the expression of invasiveness and metastasis-associated gene of human gastric carcinoma cell line]. 2003 Zhonghua Yu Fang Yi Xue Za Zhi pmid:12760791
Zhang JS et al. [Study on inhibitory effects of c9, t11-conjugated linoleic acid on migration of human gastric carcinoma cell line via cyclooxygenase-2 pathway]. 2007 Zhonghua Yu Fang Yi Xue Za Zhi pmid:18399127
Zhu Y et al. [The inhibitory effect of CLA on mice forestomach neoplasia induced by B(a)P]. 2001 Zhonghua Yu Fang Yi Xue Za Zhi pmid:11860953
Sun CH et al. [Effects of conjugated linoleic acid on expression of GLUT4 protein in skeletal muscle of insulin resistant rat]. 2007 Zhonghua Yu Fang Yi Xue Za Zhi pmid:17484206