Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kawajiri H et al. | Arachidonic and linoleic acid metabolism in mouse intestinal tissue: evidence for novel lipoxygenase activity. | 2002 | Arch. Biochem. Biophys. | pmid:11811948 |
Mitchell LA et al. | Linoleic acid, cis-epoxyoctadecenoic acids, and dihydroxyoctadecadienoic acids are toxic to Sf-21 cells in the absence of albumin. | 2002 | Toxicol. Lett. | pmid:11814707 |
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Baron CP et al. | Concentration effects in myoglobin-catalyzed peroxidation of linoleate. | 2002 | J. Agric. Food Chem. | pmid:11829662 |
Joo ST et al. | Effects of dietary conjugated linoleic acid on fatty acid composition, lipid oxidation, color, and water-holding capacity of pork loin. | 2002 | J. Anim. Sci. | pmid:11831506 |
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Pappas A et al. | Metabolic fate and selective utilization of major fatty acids in human sebaceous gland. | 2002 | J. Invest. Dermatol. | pmid:11851890 |
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Kohno H et al. | Dietary conjugated linolenic acid inhibits azoxymethane-induced colonic aberrant crypt foci in rats. | 2002 | Jpn. J. Cancer Res. | pmid:11856476 |
Demcakova E et al. | Delta-6 desaturase activity and gene expression, tissue fatty acid profile and glucose turnover rate in hereditary hypertriglyceridemic rats. | 2001 | Endocr Regul | pmid:11858764 |
Whitlock LA et al. | Fish oil and extruded soybeans fed in combination increase conjugated linoleic acids in milk of dairy cows more than when fed separately. | 2002 | J. Dairy Sci. | pmid:11860116 |
Zhu Y et al. | [The inhibitory effect of CLA on mice forestomach neoplasia induced by B(a)P]. | 2001 | Zhonghua Yu Fang Yi Xue Za Zhi | pmid:11860953 |
Lichtenstein AH et al. | Efficacy of a Therapeutic Lifestyle Change/Step 2 diet in moderately hypercholesterolemic middle-aged and elderly female and male subjects. | 2002 | J. Lipid Res. | pmid:11861668 |
Ishido E et al. | Kinetic expression for the oxidation of linoleic and arachidonic acid esters in their mixed system. | 2002 | Biosci. Biotechnol. Biochem. | pmid:11866122 |
Futakuchi M et al. | Inhibition of conjugated fatty acids derived from safflower or perilla oil of induction and development of mammary tumors in rats induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). | 2002 | Cancer Lett. | pmid:11867197 |
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van Dam RM et al. | Dietary fat and meat intake in relation to risk of type 2 diabetes in men. | 2002 | Diabetes Care | pmid:11874924 |
Elabbadi N et al. | Regulation of phosphatidic acid phosphohydrolase 1 by fatty acids. | 2002 | Lipids | pmid:11876265 |
Inouye K et al. | Deodorization of soybean proteins by enzymatic and physicochemical treatments. | 2002 | J. Agric. Food Chem. | pmid:11879052 |
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Urquhart P et al. | The effect of conjugated linoleic acid on arachidonic acid metabolism and eicosanoid production in human saphenous vein endothelial cells. | 2002 | Biochim. Biophys. Acta | pmid:11880240 |
Evans M et al. | Trans-10, cis-12 conjugated linoleic acid increases fatty acid oxidation in 3T3-L1 preadipocytes. | 2002 | J. Nutr. | pmid:11880570 |
Svahn JC et al. | Different quantities and quality of fat in milk products given to young children: effects on long chain polyunsaturated fatty acids and trans fatty acids in plasma. | 2002 | Acta Paediatr. | pmid:11885548 |
Dichtl W et al. | Linoleic acid-stimulated vascular adhesion molecule-1 expression in endothelial cells depends on nuclear factor-kappaB activation. | 2002 | Metab. Clin. Exp. | pmid:11887169 |
Bolte MR et al. | Feeding lambs high-oleate or high-linoleate safflower seeds differentially influences carcass fatty acid composition. | 2002 | J. Anim. Sci. | pmid:11890397 |
Wiegand BR et al. | Duration of feeding conjugated linoleic acid influences growth performance, carcass traits, and meat quality of finishing barrows. | 2002 | J. Anim. Sci. | pmid:11890399 |
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Du M and Ahn DU | Effect of dietary conjugated linoleic acid on the growth rate of live birds and on the abdominal fat content and quality of broiler meat. | 2002 | Poult. Sci. | pmid:11902422 |
Galindo-Cuspinera V et al. | Comparison of volatile compounds in water- and oil-soluble annatto (Bixa orellana L.) extracts. | 2002 | J. Agric. Food Chem. | pmid:11902949 |
Kikuzaki H et al. | Antioxidant properties of ferulic acid and its related compounds. | 2002 | J. Agric. Food Chem. | pmid:11902973 |
Nakaya A et al. | Helicobacter pylori alters n-6 fatty acid metabolism and prostaglandin E2 synthesis in rat gastric mucosal cells. | 2001 | J. Gastroenterol. Hepatol. | pmid:11903735 |
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Masters N et al. | Maternal supplementation with CLA decreases milk fat in humans. | 2002 | Lipids | pmid:11908905 |
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Ramanadham S et al. | Delta6-, Stearoyl CoA-, and Delta5-desaturase enzymes are expressed in beta-cells and are altered by increases in exogenous PUFA concentrations. | 2002 | Biochim. Biophys. Acta | pmid:11923099 |
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Boggia R et al. | Classification and class-modeling of "Riviera Ligure" extra-virgin olive oil using chemical-physical parameters. | 2002 | J. Agric. Food Chem. | pmid:11929311 |
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Tischendorf F et al. | Influence of a conjugated linoleic acid mixture on growth, organ weights, carcass traits and meat quality in growing pigs. | 2002 | J Anim Physiol Anim Nutr (Berl) | pmid:11972681 |
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Terpstra AH et al. | The decrease in body fat in mice fed conjugated linoleic acid is due to increases in energy expenditure and energy loss in the excreta. | 2002 | J. Nutr. | pmid:11983818 |
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