Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Funk CD et al. | Effects of selenium-deficient diets on the production of prostaglandins and other oxygenated metabolites of arachidonic acid and linoleic acid by rat and rabbit aortae. | 1987 | Biochim. Biophys. Acta | pmid:3115301 |
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Sacks FM et al. | Effect of linoleic and oleic acids on blood pressure, blood viscosity, and erythrocyte cation transport. | 1987 | J Am Coll Nutr | pmid:3584738 |
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Murphy MG et al. | Effects of membrane polyunsaturated fatty acids on opiate peptide inhibition of basal and prostaglandin E1-stimulated cyclic AMP formation in intact N1E-115 neuroblastoma cells. | 1987 | Biochem. Pharmacol. | pmid:2825714 |
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Hagve TA and Christophersen BO | In vitro effects of alpha-bromopalmitate on metabolism of essential fatty acids studied in isolated rat hepatocytes: sex differences. | 1987 | Biochim. Biophys. Acta | pmid:3099848 |
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Uotila P et al. | Relaxing effects of 15-lipoxygenase products of arachidonic acid on rat aorta. | 1987 | J. Pharmacol. Exp. Ther. | pmid:3116200 |
Mikhailidis DP et al. | High content of dietary linoleic acid does not reduce platelet reactivity in patients with hyperlipoproteinaemia. | 1987 | Eur. J. Clin. Invest. | pmid:3106056 |
MartÃnez M and Ballabriga A | Effects of parenteral nutrition with high doses of linoleate on the developing human liver and brain. | 1987 | Lipids | pmid:3106740 |
Ludwig P et al. | Modelling the reaction mechanism of the reticulocyte lipoxygenase. | 1987 | Biomed. Biochim. Acta | pmid:3109405 |
Bomalaski JS et al. | Alteration of uptake and distribution of eicosanoid precursor fatty acids by aspirin. | 1987 | Biochem. Pharmacol. | pmid:3117063 |
Maher ER et al. | Increased free-radical activity during haemodialysis? | 1987 | Nephrol. Dial. Transplant. | pmid:3114676 |
Effect of parenteral linoleate on fatty acid composition of infant brain and liver. | 1987 | Nutr. Rev. | pmid:3114686 | |
McLennan PL et al. | Dietary lipid modulation of myocardial beta-adrenergic mechanisms, Ca2+-dependent automaticity, and arrhythmogenesis in the marmoset. | 1987 | J. Cardiovasc. Pharmacol. | pmid:2444777 |
Gibian MJ and Vandenberg P | Product yield in oxygenation of linoleate by soybean lipoxygenase: the value of the molar extinction coefficient in the spectrophotometric assay. | 1987 | Anal. Biochem. | pmid:3116881 |
Ludwig P et al. | A kinetic model for lipoxygenases based on experimental data with the lipoxygenase of reticulocytes. | 1987 | Eur. J. Biochem. | pmid:3117544 |
Cook HW and Spence MW | Studies of the modulation of essential fatty acid metabolism by fatty acids in cultured neuroblastoma and glioma cells. | 1987 | Biochim. Biophys. Acta | pmid:3105586 |
Ha YL et al. | Anticarcinogens from fried ground beef: heat-altered derivatives of linoleic acid. | 1987 | Carcinogenesis | pmid:3119246 |
Griffin JF et al. | Recognition of cervical neoplasia by the estimation of a free-radical reaction product (octadeca-9,11-dienoic acid) in biopsy material. | 1987 | Clin. Chim. Acta | pmid:3568417 |
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Kaneko T et al. | Lethal effects of a linoleic acid hydroperoxide and its autoxidation products, unsaturated aliphatic aldehydes, on human diploid fibroblasts. | 1987 | Chem. Biol. Interact. | pmid:3664790 |
Das UN et al. | Uptake and distribution of cis-unsaturated fatty acids and their effect on free radical generation in normal and tumor cells in vitro. | 1987 | Free Radic. Biol. Med. | pmid:3040539 |
Nilsson A et al. | Absorption and lymphatic transport of exogenous and endogenous arachidonic and linoleic acid in the rat. | 1987 | Am. J. Physiol. | pmid:3109253 |
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Ashida H et al. | Effect of orally administered secondary autoxidation products of linoleic acid on carbohydrate metabolism in rat liver. | 1987 | Arch. Biochem. Biophys. | pmid:3688880 |
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Hagve TA and Christophersen BO | Sex-related differences in desaturation and chain elongation of essential fatty acids studied in isolated rat hepatocytes. | 1987 | Biochim. Biophys. Acta | pmid:3607076 |
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Kovár J | Hybridoma cultivation in defined serum-free media: growth-supporting substances. IV. Lipids and serum albumin. | 1987 | Folia Biol. (Praha) | pmid:3436465 |
McIntosh GH et al. | The influence of linoleate and vitamin E from sunflower seed oil on platelet function and prostaglandin production in the common marmoset monkey. | 1987 | J. Nutr. Sci. Vitaminol. | pmid:3437342 |
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Croft KD et al. | Differential inhibition of thromboxane B2 and leukotriene B4 biosynthesis by two naturally occurring acetylenic fatty acids. | 1987 | Biochim. Biophys. Acta | pmid:2822134 |
Tischinger-Wagner H et al. | [Oxidative degradation of linoleic acid methyl ester in suspensions of inorganic excipients. 1. Auto-oxidation in the presence of silicic acid products and aluminum oxide]. | 1987 | Pharmazie | pmid:2823296 |
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Clementz T et al. | Membrane potential, lipid regulation and adenylate energy charge in acyl chain modified Acholeplasma laidlawii. | 1987 | Biochim. Biophys. Acta | pmid:3567184 |
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Heifets M et al. | Effect of dietary lipids on renal function in rats with subtotal nephrectomy. | 1987 | Kidney Int. | pmid:3669493 |
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Hachey DL et al. | Human lactation: maternal transfer of dietary triglycerides labeled with stable isotopes. | 1987 | J. Lipid Res. | pmid:3681142 |
Betteridge J | Nutrition and platelet function in atherogenesis. | 1987 | Proc Nutr Soc | pmid:2893383 |
Setty BN et al. | 13-Hydroxyoctadecadienoic acid (13-HODE) stimulates prostacyclin production by endothelial cells. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3113422 |
Wan JM and Grimble RF | Effect of dietary linoleate content on the metabolic response of rats to Escherichia coli endotoxin. | 1987 | Clin. Sci. | pmid:3545648 |
Bruneau C et al. | Influence of lipid environment on insulin binding in cultured hepatoma cells. | 1987 | Biochim. Biophys. Acta | pmid:3552053 |
Loesberg C et al. | Effects of dietary poly-unsaturated fatty acids on tracheal histaminergic and cholinergic responsiveness in experimental models of bronchial hypersensitivity and hyperreactivity. | 1987 | Agents Actions | pmid:2895570 |
Bruneau C et al. | Modifications of cellular lipids induce insulin resistance in cultured hepatoma cells. | 1987 | Biochim. Biophys. Acta | pmid:3552054 |
Perez RV et al. | The effect of donor specific transfusions and dietary fatty acids on rat cardiac allograft survival. | 1987 | J. Surg. Res. | pmid:3553741 |
Berry EM et al. | Dietary fat, plasma lipoproteins, and immune function in middle-aged American men. | 1987 | Nutr Cancer | pmid:3562291 |
Nugteren DH and Kivits GA | Conversion of linoleic acid and arachidonic acid by skin epidermal lipoxygenases. | 1987 | Biochim. Biophys. Acta | pmid:3113487 |
Arca M et al. | Erythrocyte fatty acid composition and gallstone disease: results of an epidemiological survey. | 1987 | Am. J. Clin. Nutr. | pmid:3604961 |