Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Connor HD et al. | A search for oxygen-centered free radicals in the lipoxygenase/linoleic acid system. | 1986 | Biochem. Biophys. Res. Commun. | pmid:3026385 |
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Kort WJ et al. | Influence of the linoleic acid content of the diet on tumor growth in transplantable rat tumor models. | 1986 | Ann. Nutr. Metab. | pmid:3963748 |
Beneytout JL et al. | Effect of isoquinoline alkaloids on soybean lipoxygenase activity in vitro. | 1986 | Prostaglandins | pmid:3086939 |
Coene MC et al. | Inhibition of rabbit platelet activation by lipoxygenase products of arachidonic and linoleic acid. | 1986 | Thromb. Res. | pmid:3087009 |
Riemersma RA et al. | Linoleic acid content in adipose tissue and coronary heart disease. | 1986 | Br Med J (Clin Res Ed) | pmid:3087455 |
Rapoport S et al. | Hydroperoxyfatty acids inactivate the reticulocyte lipoxygenase independently of a hydroperoxidase reaction. | 1986 | FEBS Lett. | pmid:3087777 |
Okuno M et al. | Serum fatty acid concentrations in patients on postoperative parenteral nutrition with and without fat. | 1986 | Jpn J Surg | pmid:3088309 |
Heagerty AM et al. | Influence of dietary linoleic acid on leucocyte sodium transport and blood pressure. | 1986 | Br Med J (Clin Res Ed) | pmid:3089491 |
Wander RC and Berdanier CD | Effects of type of dietary fat and carbohydrate on gluconeogenesis in isolated hepatocytes from BHE rats. | 1986 | J. Nutr. | pmid:3091787 |
Ng LL and Hockaday TD | Influence of dietary linoleic acid on leucocyte sodium transport and blood pressure. | 1986 | Br Med J (Clin Res Ed) | pmid:3092960 |
Jones DB et al. | Indirect evidence of impairment of platelet desaturase enzymes in diabetes mellitus. | 1986 | Horm. Metab. Res. | pmid:3013745 |
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Marshall MW et al. | Effects of low fat diets varying in P/S ratio on nutrient intakes, fecal excretion, blood chemistry profiles, and fatty acids of adult men. | 1986 | J Am Coll Nutr | pmid:3734273 |
Parsons HG et al. | Modulation of human erythrocyte shape and fatty acids by diet. | 1986 | Biochim. Biophys. Acta | pmid:3741859 |
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Effect of age on the linoleate content of skin acylglucosylceramide in mice. | 1986 | Nutr. Rev. | pmid:3796906 | |
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Ishiura S et al. | Effects of linoleic acid and cations on the activity of a novel high-molecular weight protease, ingensin, from human placenta. | 1986 | Int. J. Biochem. | pmid:3530832 |
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Hoffmann P et al. | Circadian rhythm of eicosanoid formation as affected by dietary linoleate. | 1986 | Prostaglandins Leukot Med | pmid:3547416 |
Siegel I et al. | Inhibition of sperm motility and agglutination of sperm cells by free fatty acids in whole semen. | 1986 | Fertil. Steril. | pmid:2868925 |
Tabachnick M and Korcek L | Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. | 1986 | Biochim. Biophys. Acta | pmid:2869786 |
Stewart ME et al. | Dilutional effect of increased sebaceous gland activity on the proportion of linoleic acid in sebaceous wax esters and in epidermal acylceramides. | 1986 | J. Invest. Dermatol. | pmid:2946783 |