Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Encopresis D004688 1 associated lipids
Enuresis D004775 1 associated lipids
Onchocerciasis D009855 1 associated lipids
Malaria, Cerebral D016779 1 associated lipids
Liposarcoma D008080 1 associated lipids
Gastroschisis D020139 1 associated lipids
Fat Necrosis D005218 1 associated lipids
Facial Nerve Diseases D005155 1 associated lipids
Child Nutrition Disorders D015362 1 associated lipids
Refeeding Syndrome D055677 1 associated lipids
Pellagra D010383 1 associated lipids
Refractive Errors D012030 1 associated lipids
Carcinoma, Krebs 2 D002287 1 associated lipids
Aneurysm D000783 2 associated lipids
Spirochaetales Infections D013145 2 associated lipids
Circoviridae Infections D018173 2 associated lipids
Lymphopenia D008231 2 associated lipids
Leptospirosis D007922 2 associated lipids
Genetic Diseases, X-Linked D040181 2 associated lipids
Lactose Intolerance D007787 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Delmastro-Greenwood M et al. Nitrite and nitrate-dependent generation of anti-inflammatory fatty acid nitroalkenes. 2015 Free Radic. Biol. Med. pmid:26385079
Alvarruiz A et al. Quality and Composition of Virgin Olive Oil from Varietties Grown in Castilla-La Mancha (Spain). 2015 J Oleo Sci pmid:26369595
Frenzel E et al. α1-Antitrypsin Combines with Plasma Fatty Acids and Induces Angiopoietin-like Protein 4 Expression. 2015 J. Immunol. pmid:26363050
Mizuta K et al. Novel identification of the free fatty acid receptor FFAR1 that promotes contraction in airway smooth muscle. 2015 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:26342087
Lands B Omega-3 PUFAs Lower the Propensity for Arachidonic Acid Cascade Overreactions. 2015 Biomed Res Int pmid:26301244
Mansour AB et al. Effect of agricultural sites on differentiation between Chemlali and Neb Jmel olive oils. 2015 J Oleo Sci pmid:25833451
Alnaseri H et al. Inducible Expression of a Resistance-Nodulation-Division-Type Efflux Pump in Staphylococcus aureus Provides Resistance to Linoleic and Arachidonic Acids. 2015 J. Bacteriol. pmid:25802299
Chen S et al. Profiling of volatile compounds and associated gene expression and enzyme activity during fruit development in two cucumber cultivars. 2015 PLoS ONE pmid:25799542
Manosalva C et al. Cloning, identification and functional characterization of bovine free fatty acid receptor-1 (FFAR1/GPR40) in neutrophils. 2015 PLoS ONE pmid:25790461
Xing J et al. Determining antioxidant activities of lactobacilli cell-free supernatants by cellular antioxidant assay: a comparison with traditional methods. 2015 PLoS ONE pmid:25789875
Saccenti E et al. Strategies for individual phenotyping of linoleic and arachidonic acid metabolism using an oral glucose tolerance test. 2015 PLoS ONE pmid:25786212
Yoshida Y et al. Chemistry of lipid peroxidation products and their use as biomarkers in early detection of diseases. 2015 J Oleo Sci pmid:25766928
Guo Q et al. Impact of additives on thermally-induced trans isomers in 9c,12c linoleic acid triacylglycerol. 2015 Food Chem pmid:25529684
Chan BC et al. Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin. 2015 J. Pharm. Pharmacol. pmid:25212982
Pruzanski W et al. Diverse activity of human secretory phospholipases A2 on the migration of human vascular smooth muscle cells. 2015 Inflamm. Res. pmid:25999087
Salazar MO et al. A thin-layer chromatography autographic method for the detection of inhibitors of the Salmonella PhoP-PhoQ regulatory system. 2014 Mar-Apr Phytochem Anal pmid:24185747
Fritsche KL Linoleic acid, vegetable oils & inflammation. 2014 Jan-Feb Mo Med pmid:24645297
Hellstrand S et al. Genetic variation in FADS1 has little effect on the association between dietary PUFA intake and cardiovascular disease. 2014 J. Nutr. pmid:25008580
Huang X et al. Serum fatty acid patterns, insulin sensitivity and the metabolic syndrome in individuals with chronic kidney disease. 2014 J. Intern. Med. pmid:24011327
López A et al. Compressive mechanical properties and cytocompatibility of bone-compliant, linoleic acid-modified bone cement in a bovine model. 2014 J Mech Behav Biomed Mater pmid:24508711