Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Acidosis D000138 13 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Alcoholism D000437 27 associated lipids
Alopecia D000505 14 associated lipids
Alzheimer Disease D000544 76 associated lipids
Aneurysm D000783 2 associated lipids
Anorexia D000855 8 associated lipids
Olfaction Disorders D000857 17 associated lipids
Hypoxia D000860 23 associated lipids
Aortic Diseases D001018 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Ascites D001201 25 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Biliary Atresia D001656 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Trimborn M et al. Linoleic acid cytotoxicity to bovine lens epithelial cells: influence of albumin on linoleic acid uptake and cytotoxicity. 2000 Mar-Jun Ophthalmic Res. pmid:10754440
Hubbard NE et al. Reduction of murine mammary tumor metastasis by conjugated linoleic acid. 2000 Cancer Lett. pmid:10755392
MacDonald HB Conjugated linoleic acid and disease prevention: a review of current knowledge. 2000 J Am Coll Nutr pmid:10759137
Tomsits E et al. Effects of early nutrition on free radical formation in VLBW infants with respiratory distress. 2000 J Am Coll Nutr pmid:10763905
Punchard NA et al. Analysis of the intestinal absorption of essential fatty acids in vivo in the rat. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10765976
Mohan IK and Das UN Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10765977
Yehuda S et al. Fatty acid mixture counters stress changes in cortisol, cholesterol, and impair learning. 2000 Int. J. Neurosci. pmid:10765992
Littman ED et al. Role of protein kinase C isoenzymes in fatty acid stimulation of insulin secretion. 2000 Pancreas pmid:10766451
Mogul R et al. Oleyl sulfate reveals allosteric inhibition of soybean lipoxygenase-1 and human 15-lipoxygenase. 2000 Biochemistry pmid:10769137
Kritharides L Ascorbic acid and copper in linoleate oxidation--Dunkley revisited. 1999 Redox Rep. pmid:10772064
Siefken W et al. Regulation of cholesterol synthesis by oleic and palmitic acid in keratinocytes. 2000 Exp. Dermatol. pmid:10772388
Sasaki T et al. Dietary docosahexaenoic acid can alter the surface expression of CD4 and CD8 on T cells in peripheral blood. 2000 J. Agric. Food Chem. pmid:10775347
Liégeois C et al. Measuring antioxidant efficiency of wort, malt, and hops against the 2,2'-azobis(2-amidinopropane) dihydrochloride-induced oxidation of an aqueous dispersion of linoleic acid. 2000 J. Agric. Food Chem. pmid:10775361
Talcott ST et al. Antioxidant changes and sensory properties of carrot puree processed with and without periderm tissue. 2000 J. Agric. Food Chem. pmid:10775391
Hover CG and Kulkarni AP A simple and efficient method for hemoglobin removal from mammalian tissue cytosol by zinc sulfate and its application to the study of lipoxygenase. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780874
Charnock JS Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:10780878
McCarty MF Toward a wholly nutritional therapy for type 2 diabetes. 2000 Med. Hypotheses pmid:10783493
Kharchenko OV et al. [Kinetic mechanisms of linoleic acid oxidation by 5-lipoxygenase from Solanum tuberosum L]. 1999 Jul-Aug Ukr Biokhim Zh (1999) pmid:10791055
McEvoy TG et al. Fatty acid composition of lipids in immature cattle, pig and sheep oocytes with intact zona pellucida. 2000 J. Reprod. Fertil. pmid:10793638
Mandin O et al. Volatile compounds from potato-like model systems. 1999 J. Agric. Food Chem. pmid:10794636