Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Acidosis D000138 13 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Alcoholism D000437 27 associated lipids
Alopecia D000505 14 associated lipids
Alzheimer Disease D000544 76 associated lipids
Aneurysm D000783 2 associated lipids
Anorexia D000855 8 associated lipids
Olfaction Disorders D000857 17 associated lipids
Hypoxia D000860 23 associated lipids
Aortic Diseases D001018 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Ascites D001201 25 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Biliary Atresia D001656 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Per page 10 20 50 100 | Total 5580
Authors Title Published Journal PubMed Link
Kleinfeld AM et al. Transport of long-chain native fatty acids across lipid bilayer membranes indicates that transbilayer flip-flop is rate limiting. 1997 Biochemistry pmid:9369487
Mizushina Y et al. The inhibitory action of fatty acids on DNA polymerase beta. 1997 Biochim. Biophys. Acta pmid:9367179
Singer S et al. Correlation of lipid content and composition with liposarcoma histology and grade. 1997 Oct-Nov Ann. Surg. Oncol. pmid:9367021
Anthony FA et al. Psoralen-fatty acid adducts activate melanocyte protein kinase C: a proposed mechanism for melanogenesis induced by 8-methoxypsoralen and ultraviolet A light. 1997 Feb-Apr Photodermatol Photoimmunol Photomed pmid:9361122
Jie MS et al. Synthesis and nuclear magnetic resonance properties of all geometrical isomers of conjugated linoleic acids. 1997 Lipids pmid:9358429
Ali I and Steele JE Fatty acids stimulate trehalose synthesis in trophocytes of the cockroach (Periplaneta americana) fat body. 1997 Gen. Comp. Endocrinol. pmid:9356224
O'donnell VB and Kühn H Co-oxidation of NADH and NADPH by a mammalian 15-lipoxygenase: inhibition of lipoxygenase activity at near-physiological NADH concentrations. 1997 Biochem. J. pmid:9355754
Yamamoto A et al. Improvement of the pulmonary absorption of (Asu1,7)-eel calcitonin by various absorption enhancers and their pulmonary toxicity in rats. 1997 J Pharm Sci pmid:9344172
Heiskanen KM et al. Effect of linoleic acid, linoleic acid anilide, and arachidonic acid on the expression of adhesion molecules on human neutrophils. 1997 Arch. Toxicol. pmid:9332699
Ratnayake WM et al. Essential fatty acids and their trans geometrical isomers in powdered and liquid infant formulas sold in Canada. 1997 J. Pediatr. Gastroenterol. Nutr. pmid:9327370
Louw L et al. Keloids: peripheral and central differences in cell morphology and fatty acid compositions of lipids. 1997 Adv. Exp. Med. Biol. pmid:9322000
Eling TE et al. Modulation of epidermal growth factor signal transduction by linoleic acid metabolites. 1997 Adv. Exp. Med. Biol. pmid:9321970
Meyer C et al. Human kidney free fatty acid and glucose uptake: evidence for a renal glucose-fatty acid cycle. 1997 Am. J. Physiol. pmid:9316458
Chatterjee MT et al. Alterations in cellular lipids may be responsible for the transient nature of the yeast heat shock response. 1997 Microbiology (Reading, Engl.) pmid:9308188
Chinn KS et al. Modulation of adjuvant-induced arthritis by dietary arachidonic acid in essential fatty acid-deficient rats. 1997 Lipids pmid:9307941
Bolton-Smith C et al. Evidence for age-related differences in the fatty acid composition of human adipose tissue, independent of diet. 1997 Eur J Clin Nutr pmid:9306089
Hayakawa F et al. DNA cleavage reaction and linoleic acid peroxidation induced by tea catechins in the presence of cupric ion. 1997 Biochim. Biophys. Acta pmid:9305782
Moran JH et al. Cytotoxicity of linoleic acid diols to renal proximal tubular cells. 1997 Toxicol. Appl. Pharmacol. pmid:9299596
Rusnak A et al. Cardiolipin remodeling in a Chinese hamster lung fibroblast cell line deficient in oxidative energy production. 1997 J. Bioenerg. Biomembr. pmid:9298714
de Waart FG et al. Vitamin E supplementation in elderly lowers the oxidation rate of linoleic acid in LDL. 1997 Atherosclerosis pmid:9298686