Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

Cross Reference

Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Acidosis D000138 13 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Alcoholic Intoxication D000435 15 associated lipids
Alcoholism D000437 27 associated lipids
Alopecia D000505 14 associated lipids
Alzheimer Disease D000544 76 associated lipids
Aneurysm D000783 2 associated lipids
Anorexia D000855 8 associated lipids
Olfaction Disorders D000857 17 associated lipids
Hypoxia D000860 23 associated lipids
Aortic Diseases D001018 11 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arteriosclerosis Obliterans D001162 8 associated lipids
Ascites D001201 25 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Biliary Atresia D001656 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Sijben JW et al. Dietary linoleic acid divergently affects immune responsiveness of growing layer hens. 2000 Poult. Sci. pmid:10947178
Jeppesen PB et al. Deficiencies of essential fatty acids, vitamin A and E and changes in plasma lipoproteins in patients with reduced fat absorption or intestinal failure. 2000 Eur J Clin Nutr pmid:10951512
Cohen LA et al. The influence of different varieties of olive oil on N-methylnitrosourea(NMU)-induced mammary tumorigenesis. 2000 Jul-Aug Anticancer Res. pmid:10953289
Tůmová L and Dusek J [Effect of linoleic acid on the production of secondary metabolites]. 2000 Ceska Slov Farm pmid:10953448
Kritchevsky D Antimutagenic and some other effects of conjugated linoleic acid. 2000 Br. J. Nutr. pmid:10953669
Hennig B et al. Fatty acid-mediated activation of vascular endothelial cells. 2000 Metab. Clin. Exp. pmid:10954018
Saxena NC Inhibition of GABA(A) receptor (GABAR) currents by arachidonic acid in HEK 293 cells stably transfected with alpha1beta2gamma2 GABAR subunits. 2000 Pflugers Arch. pmid:10954324
Yang L et al. Oxidative stability of conjugated linoleic acid isomers. 2000 J. Agric. Food Chem. pmid:10956070
Griinari JM et al. Conjugated linoleic acid is synthesized endogenously in lactating dairy cows by Delta(9)-desaturase. 2000 J. Nutr. pmid:10958825
Kritchevsky D et al. Influence of conjugated linoleic acid (CLA) on establishment and progression of atherosclerosis in rabbits. 2000 J Am Coll Nutr pmid:10963467
Watkins BA and Seifert MF Conjugated linoleic acid and bone biology. 2000 J Am Coll Nutr pmid:10963468
DeLany JP and West DB Changes in body composition with conjugated linoleic acid. 2000 J Am Coll Nutr pmid:10963469
Higdon JV et al. Supplementation of postmenopausal women with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not associated with greater in vivo lipid peroxidation compared with oils rich in oleate and linoleate as assessed by plasma malondialdehyde and F(2)-isoprostanes. 2000 Am. J. Clin. Nutr. pmid:10966889
Moosmann B and Behl C Cytoprotective antioxidant function of tyrosine and tryptophan residues in transmembrane proteins. 2000 Eur. J. Biochem. pmid:10971578
Monteggia E et al. Phospholipid distribution in murine mammary adenocarcinomas induced by activated neu oncogene. 2000 Cancer Detect. Prev. pmid:10975281
Messa P et al. Abnormal arachidonic acid content of red blood cell membranes and main lithogenic factors in stone formers. 2000 Nephrol. Dial. Transplant. pmid:10978396
Kajita M et al. Enhanced enteral bioavailability of vancomycin using water-in-oil-in-water multiple emulsion incorporating highly purified unsaturated fatty acid. 2000 J Pharm Sci pmid:10980499
Kim JG et al. Reduction of aflatoxins by Korean soybean paste and its effect on cytotoxicity and reproductive toxicity--part 1. Inhibition of growth and aflatoxin production of Aspergillus parasiticus by Korean soybean paste (Doen-jang) and identification of the active component. 2000 J. Food Prot. pmid:10983810
Evans M et al. Conjugated linoleic acid suppresses triglyceride accumulation and induces apoptosis in 3T3-L1 preadipocytes. 2000 Lipids pmid:10984113
Oak J et al. Synthetically prepared Aamadori-glycated phosphatidylethanolaminecan trigger lipid peroxidation via free radical reactions. 2000 FEBS Lett. pmid:10984609