Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sammon AM | Dietary linoleic acid, immune inhibition and disease. | 1999 | Postgrad Med J | pmid:10448487 |
Lipkin M et al. | Dietary factors in human colorectal cancer. | 1999 | Annu. Rev. Nutr. | pmid:10448536 |
Nakano N et al. | Formation of 8,11,14-octadecatrienoic acid (18:3 n-4) from naturally occurring unique fatty acid, 9,12-hexadecadienoic acid (16:2 n-4), in animal cell cultures. | 1999 | J. Nutr. Sci. Vitaminol. | pmid:10450561 |
Kharchenko OV et al. | [Inhibitory effect of linoleyl-hydroxamic acid on the oxidation of linoleic acid by 12-lipoxygenase from porcine leukocytes]. | 1999 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:10457987 |
Butovich IA and Kharchenko OV | [Role of phospholipids in the regulation of activity of porcine leukocyte 12-lipoxygenase]. | 1999 Jan-Feb | Ukr Biokhim Zh (1999) | pmid:10457988 |
Warnotte C et al. | Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion. | 1999 | Mol. Cell. Endocrinol. | pmid:10459862 |
Helge JW et al. | Regular exercise modulates muscle membrane phospholipid profile in rats. | 1999 | J. Nutr. | pmid:10460197 |
Stan S et al. | Modulation of apo A-IV transcript levels and synthesis by n-3, n-6, and n-9 fatty acids in CACO-2 cells. | 1999 | J. Cell. Biochem. | pmid:10462706 |
O'Shea M et al. | Antioxidant enzyme defence responses of human MCF-7 and SW480 cancer cells to conjugated linoleic acid. | 1999 May-Jun | Anticancer Res. | pmid:10470140 |
Cunnane SC et al. | Carbon recycling into de novo lipogenesis is a major pathway in neonatal metabolism of linoleate and alpha-linolenate. | 1999 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10471127 |