Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Uterine Cervical Neoplasms D002583 10 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Breast Neoplasms D001943 24 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Cho H et al. Nonradiometric HPLC measurement of 13(S)-hydroxyoctadecadienoic acid from rat tissues. 2003 Anal. Biochem. pmid:12782030
Vargas F et al. Photochemistry and in vitro phototoxicity studies of levomepromazine (methotrimeprazine), a phototoxic neuroleptic drug. 2003 Pharmazie pmid:12779046
Ward AT et al. Fresh forage and solin supplementation on conjugated linoleic acid levels in plasma and milk. 2003 J. Dairy Sci. pmid:12778585
Yamasaki M et al. Dose-dependent effect of dietary conjugated linoleic acid on the growth of rat hepatoma dRLh-84 cells in vivo. 2002 J. Nutr. Sci. Vitaminol. pmid:12775118
Macrì A et al. Effect of linoleic acid and gamma-linolenic acid on tear production, tear clearance and on the ocular surface after photorefractive keratectomy. 2003 Graefes Arch. Clin. Exp. Ophthalmol. pmid:12768289
Aletor VA et al. The effects of conjugated linoleic acids or an alpha-glucosidase inhibitor on tissue lipid concentrations and fatty acid composition of broiler chicks fed a low-protein diet. 2003 Poult. Sci. pmid:12762403
Buckner JS and Hagen MM Triacylglycerol and phospholipid fatty acids of the silverleaf whitefly: composition and biosynthesis. 2003 Arch. Insect Biochem. Physiol. pmid:12761874
Yang YM et al. [The effects of conjugated linoleic acid on the expression of invasiveness and metastasis-associated gene of human gastric carcinoma cell line]. 2003 Zhonghua Yu Fang Yi Xue Za Zhi pmid:12760791
Buddington RK and Malo C Postnatal development of nutrient transport in the intestine of dogs. 2003 Am. J. Vet. Res. pmid:12755305
Rotta AT et al. Perfluorooctyl bromide (perflubron) attenuates oxidative injury to biological and nonbiological systems. 2003 Pediatr Crit Care Med pmid:12749658
Wang JY et al. Effect of docosahexaenoic acid and ascorbate on peroxidation of retinal membranes of ODS rats. 2003 Free Radic. Res. pmid:12747736
Gorinstein S et al. Comparison of the contents of the main biochemical compounds and the antioxidant activity of some Spanish olive oils as determined by four different radical scavenging tests. 2003 J. Nutr. Biochem. pmid:12742543
Nair VB and Panchagnula R Effect of iontophoresis and fatty acids on permeation of arginine vasopressin through rat skin. 2003 Pharmacol. Res. pmid:12742012
Mashek DG and Grummer RR Short communication: Net uptake of nonesterified long chain fatty acids by the perfused caudate lobe of the caprine liver. 2003 J. Dairy Sci. pmid:12741546
Babu US et al. Impact of high flaxseed diet on mitogen-induced proliferation, IL-2 production, cell subsets and fatty acid composition of spleen cells from pregnant and F1 generation Sprague-Dawley rats. 2003 Food Chem. Toxicol. pmid:12738196
Wiesenfeld PW et al. Flaxseed increased alpha-linolenic and eicosapentaenoic acid and decreased arachidonic acid in serum and tissues of rat dams and offspring. 2003 Food Chem. Toxicol. pmid:12738189
Ma DW et al. An enriched mixture of trans-10,cis-12-CLA inhibits linoleic acid metabolism and PGE2 synthesis in MDA-MB-231 cells. 2002 Nutr Cancer pmid:12734056
Gruffat D et al. In vitro comparison of hepatic metabolism of 9cis-11 trans and 10trans-12cis isomers of CLA in the rat. 2003 Lipids pmid:12733748
Risérus U et al. CLA and body weight regulation in humans. 2003 Lipids pmid:12733745
Inagaki K et al. Evidence of isozymes for delta6 fatty acid desaturase in rat hepatocytes. 2003 Biosci. Biotechnol. Biochem. pmid:12729021
Mun'im A et al. Antioxidative compounds from Crotalaria sessiliflora. 2003 Biosci. Biotechnol. Biochem. pmid:12729010
Mattos R et al. Polyunsaturated fatty acids and bovine interferon-tau modify phorbol ester-induced secretion of prostaglandin F2 alpha and expression of prostaglandin endoperoxide synthase-2 and phospholipase-A2 in bovine endometrial cells. 2003 Biol. Reprod. pmid:12724278
Ju JW and Jung MY Formation of conjugated linoleic acids in soybean oil during hydrogenation with a nickel catalyst as affected by sulfur addition. 2003 J. Agric. Food Chem. pmid:12720406
Chen XG et al. O/W emulsification for the self-aggregation and nanoparticle formation of linoleic acid-modified chitosan in the aqueous system. 2003 J. Agric. Food Chem. pmid:12720404
Nixon JB et al. Evaluation of eicosanoids and NSAIDs as PPARgamma ligands in colorectal carcinoma cells. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12711249
Gueck T et al. Effects of essential fatty acids on mediators of mast cells in culture. 2003 Prostaglandins Leukot. Essent. Fatty Acids pmid:12711248
Risé P et al. Relative potencies of statins in reducing cholesterol synthesis and enhancing linoleic acid metabolism. 2003 Eur. J. Pharmacol. pmid:12706457
Zhang WH et al. Model studies on protein side chain modification by 4-oxo-2-nonenal. 2003 Chem. Res. Toxicol. pmid:12703968
AbuGhazaleh AA et al. Milk conjugated linoleic acid response to fish oil supplementation of diets differing in fatty acid profiles. 2003 J. Dairy Sci. pmid:12703631
Meerarani P et al. Cholesterol attenuates linoleic acid-induced endothelial cell activation. 2003 Metab. Clin. Exp. pmid:12701065
Albers R et al. Effects of cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid (CLA) isomers on immune function in healthy men. 2003 Eur J Clin Nutr pmid:12700622
Foti MC and Ingold KU Mechanism of inhibition of lipid peroxidation by gamma-terpinene, an unusual and potentially useful hydrocarbon antioxidant. 2003 J. Agric. Food Chem. pmid:12696969
Nagler LG et al. Rate of free-radical oxidation of C18 diene and triene fatty acids in aqueous micellar solutions and effectiveness of beta-carotene as an inhibitor of their oxidation. 2003 Biochemistry Mosc. pmid:12693967
Prout RE and Odutuga AA Fatty acid composition of neutral lipids and phospholipids of enamel and dentine from human molars. 1974 Arch. Oral Biol. pmid:12692911
Itakura K and Uchida K Lysine-derived fluorophores formed by autoxidation of linoleic acid. 2003 Chem. Phys. Lipids pmid:12691851
Bruder ED et al. An oxidized metabolite of linoleic acid stimulates corticosterone production by rat adrenal cells. 2003 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:12689852
Nakanishi T et al. Dietary conjugated linoleic acid reduces cerebral prostaglandin E(2) in mice. 2003 Neurosci. Lett. pmid:12686384
Qian SY et al. Identification of all classes of spin-trapped carbon-centered radicals in soybean lipoxygenase-dependent lipid peroxidations of omega-6 polyunsaturated fatty acids via LC/ESR, LC/MS, and tandem MS. 2003 Free Radic. Biol. Med. pmid:12684086
Davidson BC et al. Individual fatty acids influence cultured human liver cells differently when compared to plant oils. 2003 Jan-Feb Anticancer Res. pmid:12680255
Torres-Duarte AP and Vanderhoek JY Conjugated linoleic acid exhibits stimulatory and inhibitory effects on prostanoid production in human endothelial cells and platelets. 2003 Biochim. Biophys. Acta pmid:12676356
Yang XF et al. In vitro release and antibacterial activity of poly (oleic/linoleic acid dimer: sebacic acid)-gentamicin. 2003 Acta Pharmacol. Sin. pmid:12676068
Considine MJ et al. Superoxide stimulates a proton leak in potato mitochondria that is related to the activity of uncoupling protein. 2003 J. Biol. Chem. pmid:12672801
Siddhuraju P and Becker K Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves. 2003 J. Agric. Food Chem. pmid:12670148
Kondo H et al. Digestion and assimilation features of dietary DAG in the rat small intestine. 2003 Lipids pmid:12669816
Yang M and Cook ME Dietary CLA decreased weight loss and extended survival following the onset of kidney failure in NZB/W F1 mice. 2003 Lipids pmid:12669815
Takahashi Y et al. Activity and mRNA levels of enzymes involved in hepatic fatty acid synthesis and oxidation in mice fed conjugated linoleic acid. 2003 Biochim. Biophys. Acta pmid:12668178
Mitchell LA et al. Linoleic acid metabolites act to increase contractility in isolated rat heart. 2002 Cardiovasc. Toxicol. pmid:12665667
Kelavkar U et al. 15-lipoxygenase-1 overexpression in prostate adenocarcinoma. 2002 Adv. Exp. Med. Biol. pmid:12664577
Eitel K et al. Protein kinase C delta activation and translocation to the nucleus are required for fatty acid-induced apoptosis of insulin-secreting cells. 2003 Diabetes pmid:12663471
Djoussé L et al. Dietary linolenic acid and carotid atherosclerosis: the National Heart, Lung, and Blood Institute Family Heart Study. 2003 Am. J. Clin. Nutr. pmid:12663278
Kark JD et al. Adipose tissue n-6 fatty acids and acute myocardial infarction in a population consuming a diet high in polyunsaturated fatty acids. 2003 Am. J. Clin. Nutr. pmid:12663274
Lee C et al. Quantitative trait loci mapping for fatty acid contents in the backfat on porcine chromosomes 1, 13, and 18. 2003 Mol. Cells pmid:12661762
Chartrand R et al. Effect of dietary fat sources on systemic and intrauterine synthesis of prostaglandins during early pregnancy in gilts. 2003 J. Anim. Sci. pmid:12661653
Sakono M et al. Combined effects of dietary conjugated linoleic acid and sesamin triacylglycerol and ketone body production in rat liver. 2002 J. Nutr. Sci. Vitaminol. pmid:12656216
Ramachandran S et al. Oxidants and antioxidants affect the expression of glycodelin. 2003 Free Radic. Biol. Med. pmid:12654469
Burton M et al. Synthesis, structure-activity relationship and in vitro evaluation of coelenterazine and coelenteramine derivatives as inhibitors of lipid peroxidation. 2003 Free Radic. Res. pmid:12653203
Maccarrone M et al. Lipoxygenase activity during parabolic flights. 2001 J Gravit Physiol pmid:12650198
Mackle TR et al. Effects of abomasal infusion of conjugated linoleic acid on milk fat concentration and yield from pasture-fed dairy cows. 2003 J. Dairy Sci. pmid:12647970
Joo NE and Park CS Inhibition of excitotoxicity in cultured rat cortical neurons by a mixture of conjugated linoleic acid isomers. 2003 Pharmacol. Res. pmid:12644387
Adlof RO and List GR Synthesis and analysis of symmetrical and nonsymmetrical disaturated/monounsaturated triacylglycerols. 2003 J. Agric. Food Chem. pmid:12643679
Turgeon D et al. Glucuronidation of arachidonic and linoleic acid metabolites by human UDP-glucuronosyltransferases. 2003 J. Lipid Res. pmid:12639971
Park KY et al. Antimutagenic effects of doenjang (Korean fermented soypaste) and its active compounds. 2003 Feb-Mar Mutat. Res. pmid:12628502
Bauman DE and Griinari JM Nutritional regulation of milk fat synthesis. 2003 Annu. Rev. Nutr. pmid:12626693
Enoki M et al. Oxidative degradation of cis- and trans-1,4-polyisoprenes and vulcanized natural rubber with enzyme-mediator systems. 2003 Mar-Apr Biomacromolecules pmid:12625726
Fernández-Moya V et al. Temperature-related non-homogeneous fatty acid desaturation in sunflower (Helianthus annuus L.) seeds. 2003 Planta pmid:12624771
Adam O et al. Influence of dietary linoleic acid intake with different fat intakes on arachidonic acid concentrations in plasma and platelet lipids and eicosanoid biosynthesis in female volunteers. 2003 Ann. Nutr. Metab. pmid:12624485
Yang H et al. Conjugated linoleic acid inhibits mutagenesis by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the prostate of Big Blue rats. 2003 Mutagenesis pmid:12621076
Bergman M et al. Scavenging of reactive oxygen species by a novel glucurinated flavonoid antioxidant isolated and purified from spinach. 2003 Phytochemistry pmid:12620328
Kishino S et al. Structural analysis of conjugated linoleic acid produced by Lactobacillus plantarum, and factors affecting isomer production. 2003 Biosci. Biotechnol. Biochem. pmid:12619692
Koba K et al. Effect of phytate in soy protein on the serum and liver cholesterol levels and liver fatty acid profile in rats. 2003 Biosci. Biotechnol. Biochem. pmid:12619668
Henriksen EJ et al. Isomer-specific actions of conjugated linoleic acid on muscle glucose transport in the obese Zucker rat. 2003 Am. J. Physiol. Endocrinol. Metab. pmid:12618357
Waddington EI et al. Fatty acid oxidation products in human atherosclerotic plaque: an analysis of clinical and histopathological correlates. 2003 Atherosclerosis pmid:12618275
Cui YF et al. Effect of unsaturated fatty acid on muscarinic current in guinea pig gastric antral circular myocytes. 2003 Acta Pharmacol. Sin. pmid:12617780
Gonzalez S et al. Oxidation and textural characteristics of butter and ice cream with modified fatty acid profiles. 2003 J. Dairy Sci. pmid:12613850
Campbell W et al. The impact of fortification with conjugated linoleic acid (CLA) on the quality of fluid milk. 2003 J. Dairy Sci. pmid:12613847
Arab L Biomarkers of fat and fatty acid intake. 2003 J. Nutr. pmid:12612178
Yamasaki M et al. Immunoglobulin and cytokine production from spleen lymphocytes is modulated in C57BL/6J mice by dietary cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid. 2003 J. Nutr. pmid:12612153
Xu X et al. Short-term intake of conjugated linoleic acid inhibits lipoprotein lipase and glucose metabolism but does not enhance lipolysis in mouse adipose tissue. 2003 J. Nutr. pmid:12612134
Barabino S et al. Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. 2003 Cornea pmid:12605039
Castillo M et al. Effects of dietary fish oil on the fatty acid composition of the main lipid classes of chick plasma lipoproteins. 2002 J. Physiol. Biochem. pmid:12603006
Garcia MR et al. Age at puberty, total fat and conjugated linoleic acid content of carcass, and circulating metabolic hormones in beef heifers fed a diet high in linoleic acid beginning at four months of age. 2003 J. Anim. Sci. pmid:12597397
Tsydendambaev VD and Vereshchagin AG Changes in triacylglycerol composition during ripening of sea buckthorn (Hippophaë rhamnoides L.) seeds. 2003 J. Agric. Food Chem. pmid:12590468
Liang CF et al. Effects of epidermal growth factor and linoleic acid on lipid contents in human intestinal C2BBe1 cells. 2002 IUBMB Life pmid:12587978
Badinga L et al. Dietary conjugated linoleic acid alters hepatic lipid content and fatty acid composition in broiler chickens. 2003 Poult. Sci. pmid:12580252
Bazinet RP et al. Whole-body beta-oxidation of 18:2omega6 and 18:3omega3 in the pig varies markedly with weaning strategy and dietary 18:3omega3. 2003 J. Lipid Res. pmid:12576513
Ostrowska E et al. Conjugated linoleic acid decreases fat accretion in pigs: evaluation by dual-energy X-ray absorptiometry. 2003 Br. J. Nutr. pmid:12575906
Huang F et al. [Studies on the supercritical CO2 fluid extraction and separation of psoralen, isopsoralen and fatty oils from Psoralea corylifolia]. 2000 Zhong Yao Cai pmid:12575152
Yang D et al. [Study on lipids and other volatile constituents in Pheretima aspergillum]. 2000 Zhong Yao Cai pmid:12575114
Yuan Y et al. [Chemical constituents of Girardinia palmata ssp ciliata]. 1999 Zhong Yao Cai pmid:12575105
Zhang X et al. [Supercritical-CO2 fluid extraction of the fatty oil in Terminalia chebula and GC-MS analysis]. 1997 Zhong Yao Cai pmid:12572426
Cho HJ et al. Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12571082
Rollin X et al. The effects of dietary lipid and strain difference on polyunsaturated fatty acid composition and conversion in anadromous and landlocked salmon (Salmo salar L.) parr. 2003 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:12568812
Sher J et al. Dietary conjugated linoleic acid lowers plasma cholesterol during cholesterol supplementation, but accentuates the atherogenic lipid profile during the acute phase response in hamsters. 2003 J. Nutr. pmid:12566483
Ascherio A Epidemiologic studies on dietary fats and coronary heart disease. 2002 Am. J. Med. pmid:12566133
Lee JY et al. Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. 2003 J. Lipid Res. pmid:12562875
Valianpour F et al. Linoleic acid supplementation of Barth syndrome fibroblasts restores cardiolipin levels: implications for treatment. 2003 J. Lipid Res. pmid:12562862
Gorard DA Enteral nutrition in Crohn's disease: fat in the formula. 2003 Eur J Gastroenterol Hepatol pmid:12560753
Nuñez A et al. Purification of lipoxygenase from Chlorella: production of 9- and 13-hydroperoxide derivatives of linoleic acid. 2002 Lipids pmid:12558051
Llor X et al. The effects of fish oil, olive oil, oleic acid and linoleic acid on colorectal neoplastic processes. 2003 Clin Nutr pmid:12553953
Shi Z et al. [Analysis of physicochemical property and composition of fatty acid of almond oil]. 1999 Se Pu pmid:12552899