| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Uterine Cervical Neoplasms | D002583 | 10 associated lipids |
| Hypoxia | D000860 | 23 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
Linoelaidic acid
Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.
Cross Reference
Introduction
To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Linoelaidic acid?
Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Linoelaidic acid
PubChem Associated disorders and diseases
What pathways are associated with Linoelaidic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Linoelaidic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Linoelaidic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Linoelaidic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Linoelaidic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Linoelaidic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Linoelaidic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Neri S et al. | Association of alpha-interferon and acetyl cysteine in patients with chronic C hepatitis. | 2000 | Panminerva Med | pmid:11218623 |
| Garcia JR et al. | Macrophages transfer [14C]-labelled fatty acids to pancreatic islets in culture. | 2001 | Cell Biochem. Funct. | pmid:11223866 |
| Ogawa J et al. | Conjugated linoleic acid accumulation via 10-hydroxy-12-octadecaenoic acid during microaerobic transformation of linoleic acid by Lactobacillus acidophilus. | 2001 | Appl. Environ. Microbiol. | pmid:11229917 |
| Osman H et al. | Fatty acids bind to the fungal elicitor cryptogein and compete with sterols. | 2001 | FEBS Lett. | pmid:11231013 |
| Dandona P et al. | The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation. | 2001 | J. Clin. Endocrinol. Metab. | pmid:11232024 |
| Sell JL et al. | Metabolizable energy value of conjugated linoleic acid for broiler chicks and laying hens. | 2001 | Poult. Sci. | pmid:11233010 |
| Du M et al. | Volatile profiles and lipid oxidation of irradiated cooked chicken meat from laying hens fed diets containing conjugated linoleic acid. | 2001 | Poult. Sci. | pmid:11233015 |
| Baer RJ et al. | Composition and properties of milk and butter from cows fed fish oil. | 2001 | J. Dairy Sci. | pmid:11233018 |
| Hauville C et al. | Radiation induced peroxidation of polyunsaturated fatty acids: recent results on formation of hydroperoxides. | 2001 | Can. J. Physiol. Pharmacol. | pmid:11233566 |
| Aydin R et al. | Olive oil prevents the adverse effects of dietary conjugated linoleic acid on chick hatchability and egg quality. | 2001 | J. Nutr. | pmid:11238762 |
| Igarashi M and Miyazawa T | The growth inhibitory effect of conjugated linoleic acid on a human hepatoma cell line, HepG2, is induced by a change in fatty acid metabolism, but not the facilitation of lipid peroxidation in the cells. | 2001 | Biochim. Biophys. Acta | pmid:11239819 |
| Pfeuffer M and Schrezenmeir J | Bioactive substances in milk with properties decreasing risk of cardiovascular diseases. | 2000 | Br. J. Nutr. | pmid:11242460 |
| Gill HS and Cross ML | Anticancer properties of bovine milk. | 2000 | Br. J. Nutr. | pmid:11242461 |
| George P et al. | Phospholipids reacylation and palmitoylcoa control tumour necrosis factor-alpha sensitivity. | 2001 | Cytokine | pmid:11243703 |
| Slim R et al. | The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11243918 |
| Boudreau MD et al. | Suppression of tumor cell growth both in nude mice and in culture by n-3 polyunsaturated fatty acids: mediation through cyclooxygenase-independent pathways. | 2001 | Cancer Res. | pmid:11245439 |
| Loreau O et al. | Sequential substitution of 1,2-dichloro-ethene: a convenient stereoselective route to (9Z,11E)-, (10E,12Z)- and (10Z,12Z)-. | 2001 | Chem. Phys. Lipids | pmid:11245835 |
| Michels KB et al. | Dietary antioxidant vitamins, retinol, and breast cancer incidence in a cohort of Swedish women. | 2001 | Int. J. Cancer | pmid:11251982 |
| Korotkova M et al. | Maternal essential fatty acid deficiency depresses serum leptin levels in suckling rat pups. | 2001 | J. Lipid Res. | pmid:11254747 |
| Higdon JV et al. | Supplementation of postmenopausal women with fish oil does not increase overall oxidation of LDL ex vivo compared to dietary oils rich in oleate and linoleate. | 2001 | J. Lipid Res. | pmid:11254753 |
| Xue Y et al. | [Effects of conjugated linoleic acid on the metastasis of mouse melanoma B16-MB]. | 2001 | Wei Sheng Yan Jiu | pmid:11255760 |
| Warner K et al. | Effect of oleic and linoleic acids on the production of deep-fried odor in heated triolein and trilinolein. | 2001 | J. Agric. Food Chem. | pmid:11262047 |
| Bassaganya-Riera J et al. | Effects of dietary conjugated linoleic acid in nursery pigs of dirty and clean environments on growth, empty body composition, and immune competence. | 2001 | J. Anim. Sci. | pmid:11263832 |
| Ponticelli F et al. | Synthesis and antiperoxidant activity of new phenolic O-glycosides. | 2001 | Carbohydr. Res. | pmid:11269397 |
| Turnock L et al. | Dietary supplementation with conjugated linoleic acid does not alter the resistance of mice to Listeria monocytogenes infection. | 2001 | Lipids | pmid:11269693 |
| Chuang LT et al. | Effect of conjugated linoleic acid on fungal delta6-desaturase activity in a transformed yeast system. | 2001 | Lipids | pmid:11269694 |
| Precht D et al. | Overestimates of oleic and linoleic acid contents in materials containing trans fatty acids and analyzed with short packed gas chromatographic columns. | 2001 | Lipids | pmid:11269704 |
| Kumamoto M et al. | Effects of pH and metal ions on antioxidative activities of catechins. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11272815 |
| Cunnane SC et al. | Beta-oxidation of linoleate in obese men undergoing weight loss. | 2001 | Am. J. Clin. Nutr. | pmid:11273844 |
| Elias SL and Innis SM | Infant plasma trans, n-6, and n-3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and length. | 2001 | Am. J. Clin. Nutr. | pmid:11273857 |
| Freeman VL et al. | Assessing the effect of fatty acids on prostate carcinogenesis in humans: does self-reported dietary intake rank prostatic exposure correctly? | 2001 | Am. J. Clin. Nutr. | pmid:11273858 |
| Lim KT et al. | Antioxidant activity of a Rhus verniciflua Stokes ethanol extract. | 2001 | Food Chem. Toxicol. | pmid:11278054 |
| Mogul R and Holman TR | Inhibition studies of soybean and human 15-lipoxygenases with long-chain alkenyl sulfate substrates. | 2001 | Biochemistry | pmid:11284695 |
| Poirier H et al. | Differential involvement of peroxisome-proliferator-activated receptors alpha and delta in fibrate and fatty-acid-mediated inductions of the gene encoding liver fatty-acid-binding protein in the liver and the small intestine. | 2001 | Biochem. J. | pmid:11284737 |
| Ikeda I et al. | Reduced hepatic triglyceride secretion in rats fed docosahexaenoic acid-rich fish oil suppresses postprandial hypertriglyceridemia. | 2001 | J. Nutr. | pmid:11285319 |
| Chouinard PY et al. | Effect of dietary lipid source on conjugated linoleic acid concentrations in milk fat. | 2001 | J. Dairy Sci. | pmid:11286421 |
| Collett ED et al. | n-6 and n-3 polyunsaturated fatty acids differentially modulate oncogenic Ras activation in colonocytes. | 2001 | Am. J. Physiol., Cell Physiol. | pmid:11287318 |
| Liu Q et al. | Genetic modification of cotton seed oil using inverted-repeat gene-silencing techniques. | 2000 | Biochem. Soc. Trans. | pmid:11288706 |
| Palmantier R et al. | Cis-polyunsaturated fatty acids stimulate beta1 integrin-mediated adhesion of human breast carcinoma cells to type IV collagen by activating protein kinases C-epsilon and -mu. | 2001 | Cancer Res. | pmid:11289113 |
| Moran JH et al. | Analysis of the toxic effects of linoleic acid, 12,13-cis-epoxyoctadecenoic acid, and 12,13-dihydroxyoctadecenoic acid in rabbit renal cortical mitochondria. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11298501 |
| Mpagi JL et al. | Hyperreactive onchocerciasis exhibits reduced arachidonate and linoleate levels in serum triglycerides. | 2000 | Am. J. Trop. Med. Hyg. | pmid:11304059 |
| Moran JH et al. | Defining mechanisms of toxicity for linoleic acid monoepoxides and diols in Sf-21 cells. | 2001 | Chem. Res. Toxicol. | pmid:11304132 |
| Yamasaki M et al. | Effect of dietary conjugated linoleic acid on lipid peroxidation and histological change in rat liver tissues. | 2000 | J. Agric. Food Chem. | pmid:11312809 |
| Park Y et al. | Comparison of methylation procedures for conjugated linoleic acid and artifact formation by commercial (trimethylsilyl) diazomethane. | 2001 | J. Agric. Food Chem. | pmid:11312828 |
| Hurst WJ et al. | Determination of conjugated linoleic acid (CLA) concentrations in milk chocolate. | 2001 | J. Agric. Food Chem. | pmid:11312847 |
| Yen GC et al. | Isolation and characterization of antioxidant compounds from Aspergillus candidus broth filtrate. | 2001 | J. Agric. Food Chem. | pmid:11312875 |
| Duh PD et al. | Antioxidant effects of water extracts from barley (Hordeum vulgare L.) prepared under different roasting temperatures. | 2001 | J. Agric. Food Chem. | pmid:11312880 |
| Nakagawa H et al. | Resveratrol inhibits human breast cancer cell growth and may mitigate the effect of linoleic acid, a potent breast cancer cell stimulator. | 2001 | J. Cancer Res. Clin. Oncol. | pmid:11315261 |
| Miner JL et al. | Conjugated linoleic acid (CLA), body fat, and apoptosis. | 2001 | Obes. Res. | pmid:11316347 |
| Burczynski JM et al. | Changes in mitochondrial and microsomal lipid peroxidation and fatty acid profiles in adrenal glands, testes, and livers from alpha-tocopherol-deficient rats. | 2001 | Free Radic. Biol. Med. | pmid:11316583 |
| Spiteller G | Peroxidation of linoleic acid and its relation to aging and age dependent diseases. | 2001 | Mech. Ageing Dev. | pmid:11322990 |
| Spiteller P et al. | Aldehydic lipid peroxidation products derived from linoleic acid. | 2001 | Biochim. Biophys. Acta | pmid:11325611 |
| Samadi A et al. | Mechanism of lipid peroxidation photosensitized by tiaprofenic acid: product studies using linoleic acid and 1,4-cyclohexadienes as model substrates. | 2001 | Photochem. Photobiol. | pmid:11332030 |
| Benito P et al. | The effect of conjugated linoleic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. | 2001 | Lipids | pmid:11337976 |
| Benito P et al. | The effect of conjugated linoleic acid on plasma lipoproteins and tissue fatty acid composition in humans. | 2001 | Lipids | pmid:11337977 |
| Fu Z et al. | 1-14C-linoleic acid distribution in various tissue lipids of guinea pigs following an oral dose. | 2001 | Lipids | pmid:11337980 |
| Fukushima M et al. | Effects of diets enriched in n-6 or n-3 fatty acids on cholesterol metabolism in older rats chronically fed a cholesterol-enriched diet. | 2001 | Lipids | pmid:11337981 |
| Adlof RO et al. | Changes in conjugated linoleic acid composition within samples obtained from a single source. | 2001 | Lipids | pmid:11337988 |
| Cox JE et al. | Celiac vagotomy reduces suppression of feeding by jejunal fatty acid infusions. | 2001 | Neuroreport | pmid:11338171 |
| Orihara T et al. | Effect of Helicobacter pylori eradication on gastric mucosal phospholipid content and its fatty acid composition. | 2001 | J. Gastroenterol. Hepatol. | pmid:11339417 |
| Mattes RD | Oral exposure to butter, but not fat replacers elevates postprandial triacylglycerol concentration in humans. | 2001 | J. Nutr. | pmid:11340105 |
| Ritzenthaler KL et al. | Estimation of conjugated linoleic acid intake by written dietary assessment methodologies underestimates actual intake evaluated by food duplicate methodology. | 2001 | J. Nutr. | pmid:11340114 |
| Singh S et al. | Transgenic expression of a delta 12-epoxygenase gene in Arabidopsis seeds inhibits accumulation of linoleic acid. | 2001 | Planta | pmid:11346964 |
| Asano T | [Catabolic substance in human adipose tissue]. | 2001 | Nippon Rinsho | pmid:11347129 |
| Szymczyk B et al. | Effects of conjugated linoleic acid on growth performance, feed conversion efficiency, and subsequent carcass quality in broiler chickens. | 2001 | Br. J. Nutr. | pmid:11348561 |
| Pruzanski W et al. | Mitogenic effect of lipoproteins on human vascular smooth muscle cells: the impact of hydrolysis by gr II A phospholipase A(2). | 2001 | Lab. Invest. | pmid:11351047 |
| Kelder B et al. | Expression of fungal desaturase genes in cultured mammalian cells. | 2001 | Mol. Cell. Biochem. | pmid:11354256 |
| Waddington E et al. | Identification and quantitation of unique fatty acid oxidation products in human atherosclerotic plaque using high-performance liquid chromatography. | 2001 | Anal. Biochem. | pmid:11355856 |
| Clouet P et al. | Mitochondrial respiration on rumenic and linoleic acids. | 2001 | Biochem. Soc. Trans. | pmid:11356175 |
| Devery R et al. | Conjugated linoleic acid and oxidative behaviour in cancer cells. | 2001 | Biochem. Soc. Trans. | pmid:11356179 |
| Fuller MA et al. | Activity of soybean lipoxygenase isoforms against esterified fatty acids indicates functional specificity. | 2001 | Arch. Biochem. Biophys. | pmid:11361131 |
| Tijet N et al. | Biogenesis of volatile aldehydes from fatty acid hydroperoxides: molecular cloning of a hydroperoxide lyase (CYP74C) with specificity for both the 9- and 13-hydroperoxides of linoleic and linolenic acids. | 2001 | Arch. Biochem. Biophys. | pmid:11368353 |
| Masuda T et al. | Chemical studies on antioxidant mechanism of curcumin: analysis of oxidative coupling products from curcumin and linoleate. | 2001 | J. Agric. Food Chem. | pmid:11368633 |
| Kimoto N et al. | Site-dependent modulating effects of conjugated fatty acids from safflower oil in a rat two-stage carcinogenesis model in female Sprague-Dawley rats. | 2001 | Cancer Lett. | pmid:11368872 |
| Bretillon L et al. | Isomerization increases the postprandial oxidation of linoleic acid but not alpha-linolenic acid in men. | 2001 | J. Lipid Res. | pmid:11369808 |
| Nakagawa H et al. | Growth inhibitory effects of diallyl disulfide on human breast cancer cell lines. | 2001 | Carcinogenesis | pmid:11375895 |
| Rahman SM et al. | Effects of conjugated linoleic acid on serum leptin concentration, body-fat accumulation, and beta-oxidation of fatty acid in OLETF rats. | 2001 | Nutrition | pmid:11377131 |
| Sauer LA et al. | Polyunsaturated fatty acids, melatonin, and cancer prevention. | 2001 | Biochem. Pharmacol. | pmid:11377374 |
| Vermunt SH et al. | The metabolism of linoleic acid in healthy subjects after intake of a single dose of (13)C-linoleic acid. | 2001 | Eur J Clin Nutr | pmid:11378804 |
| Bulgarella JA et al. | Modulation of prostaglandin H synthase activity by conjugated linoleic acid (CLA) and specific CLA isomers. | 2001 | Lipids | pmid:11383694 |
| Sisk MB et al. | Dietary conjugated linoleic acid reduces adiposity in lean but not obese Zucker rats. | 2001 | J. Nutr. | pmid:11385051 |
| Misikangas M et al. | High linoleic acid, low vegetable, and high oleic acid, high vegetable diets affect platelet activation similarly in healthy women and men. | 2001 | J. Nutr. | pmid:11385056 |
| Baumgard LH et al. | Milk fat synthesis in dairy cows is progressively reduced by increasing supplemental amounts of trans-10, cis-12 conjugated linoleic acid (CLA). | 2001 | J. Nutr. | pmid:11385065 |
| Graczyk TK and Shiff CJ | Recovery of avian schistosome cercariae from water using penetration stimulant matrix with an unsaturated fatty acid. | 2000 Sep-Oct | Am. J. Trop. Med. Hyg. | pmid:11388510 |
| Saija A et al. | In vitro evaluation of the antioxidant activity and biomembrane interaction of the lazaroid U-74389G. | 2001 | Life Sci. | pmid:11388688 |
| Thomas MJ et al. | Isoprostane levels in lipids extracted from atherosclerotic arteries of nonhuman primates. | 2001 | Free Radic. Biol. Med. | pmid:11390178 |
| Amet Y et al. | Adaptation to chronic ethanol administration emphasized by fatty acid hydroxylations in rat liver and kidney microsomes. | 2000 | Eur J Nutr | pmid:11395987 |
| Jung MO et al. | Effects of temperature and agitation rate on the formation of conjugated linoleic acids in soybean oil during hydrogenation process. | 2001 | J. Agric. Food Chem. | pmid:11410002 |
| Hsi LC et al. | Evaluation of the activity and localization of 15-lipoxygenase-1 after introduction into human colorectal carcinoma Caco-2 cells. | 2001 Apr-May | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11418015 |
| Okita M et al. | Effect of arachidonic acid-rich oil on lipids and arachidonate metabolites in ethanol- treated rats. | 2001 Apr-May | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11418023 |
| Abeywardena MY et al. | Dietary n-3 and n-6 polyunsaturated oils and airway contractility. | 2001 Apr-May | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11418024 |
| Iwase H et al. | Thiol-oxidizing agent diamide and acidic pH enhance lipid peroxidation of rat heart mitochondria and cardiolipin-cytochrome c complex. | 2001 | IUBMB Life | pmid:11419694 |
| Kamphuis MM et al. | Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid. | 2001 | Eur J Clin Nutr | pmid:11423927 |
| Swan JE et al. | Total body electrical conductivity (TOBEC) measurement of compositional differences in hams, loins, and bellies from conjugated linoleic acid (CLA)-fed stress-genotype pigs. | 2001 | J. Anim. Sci. | pmid:11424684 |
| McCarty MF | Current prospects for controlling cancer growth with non-cytotoxic agents--nutrients, phytochemicals, herbal extracts, and available drugs. | 2001 | Med. Hypotheses | pmid:11425277 |
| McCarty MF | The chlorophyll metabolite phytanic acid is a natural rexinoid--potential for treatment and prevention of diabetes. | 2001 | Med. Hypotheses | pmid:11425290 |
| Kim JY et al. | Lipid and fatty acid analysis of fresh and frozen-thawed immature and in vitro matured bovine oocytes. | 2001 | Reproduction | pmid:11425337 |
| Salzano P et al. | [Prevention of gestational hypertension with calcium, linoleic acid, mono and polyunsaturated fatty acid supplements]. | 2001 | Minerva Ginecol | pmid:11431639 |
| Sauer LA et al. | Melatonin inhibits fatty acid transport in inguinal fat pads of hepatoma 7288CTC-bearing and normal Buffalo rats via receptor-mediated signal transduction. | 2001 | Life Sci. | pmid:11432449 |
| Nomura T et al. | A long-lasting facilitation of hippocampal neurotransmission via a phospholipase A2 signaling pathway. | 2001 | Life Sci. | pmid:11432454 |