Linoelaidic acid

Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone.

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Introduction

To understand associated biological information of Linoelaidic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Linoelaidic acid?

Linoelaidic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Linoelaidic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Tuberculosis D014376 20 associated lipids
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Uterine Cervical Neoplasms D002583 10 associated lipids
Hypoxia D000860 23 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Adenocarcinoma D000230 166 associated lipids
Breast Neoplasms D001943 24 associated lipids
Per page 10 20 50 100 | Total 198

PubChem Associated disorders and diseases

What pathways are associated with Linoelaidic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Linoelaidic acid?

Related references are published most in these journals:

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What functions are associated with Linoelaidic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Linoelaidic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Linoelaidic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Linoelaidic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Linoelaidic acid

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Authors Title Published Journal PubMed Link
Smith WG et al. Lipoprotein susceptibility to oxidation in the macromolecular fraction of plasma: relation to plasma lipids and oleate/linoleate ratio in comparison with whole plasma in hypertriglyceridemia. 2002 Clin. Chim. Acta pmid:11750269
Smith WG et al. Simple and rapid assessment of lipoprotein susceptibility to oxidation in the macromolecule fraction of plasma. 2002 Clin. Chim. Acta pmid:11750270
Park Y and Pariza MW Lipoxygenase inhibitors inhibit heparin-releasable lipoprotein lipase activity in 3T3-L1 adipocytes and enhance body fat reduction in mice by conjugated linoleic acid. 2001 Biochim. Biophys. Acta pmid:11750884
Larqué E et al. Dietary trans fatty acids in early life: a review. 2001 Early Hum. Dev. pmid:11755033
Mottaran E et al. Lipid peroxidation contributes to immune reactions associated with alcoholic liver disease. 2002 Free Radic. Biol. Med. pmid:11755315
Ohnuki K et al. Increased energy metabolism and suppressed body fat accumulation in mice by a low concentration of conjugated linoleic acid. 2001 Biosci. Biotechnol. Biochem. pmid:11758910
Ip C et al. Control of rat mammary epithelium proliferation by conjugated linoleic acid. 2001 Nutr Cancer pmid:11759286
Yang H et al. Modulation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mutation in the cecum and colon of big blue rats by conjugated linoleic acid and 1,2-dithiole-3-thione. 2001 Nutr Cancer pmid:11759290
Radschuweit A et al. Capillary zone electrophoresis with electrochemical detection--a simple and effective method to analyze oxygen-consuming and peroxide-forming processes. 2001 J Chromatogr A pmid:11765078
Matsingou TC et al. Aqueous infusions of Mediterranean herbs exhibit antioxidant activity towards iron promoted oxidation of phospholipids, linoleic acid, and deoxyribose. 2001 Free Radic. Res. pmid:11767417
Eggert JM et al. Effects of conjugated linoleic acid on the belly firmness and fatty acid composition of genetically lean pigs. 2001 J. Anim. Sci. pmid:11768116
Chuang LT et al. Inhibitory effect of conjugated linoleic acid on linoleic acid elongation in transformed yeast with human elongase. 2001 Lipids pmid:11768153
Miller A et al. Modulation of arachidonic acid distribution by conjugated linoleic acid isomers and linoleic acid in MCF-7 and SW480 cancer cells. 2001 Lipids pmid:11768161
Olson RE The key to an enigma: how do dietary polyunsaturated fatty acids lower serum cholesterol? 2002 J. Nutr. pmid:11773520
Tripathi AK et al. A physiochemical mechanism of hemozoin (beta-hematin) synthesis by malaria parasite. 2002 Biochem. Biophys. Res. Commun. pmid:11779214
Birnbaum L Addition of conjugated linoleic acid to a herbal anticellulite pill. 2001 Sep-Oct Adv Ther pmid:11783459
De Vriese SR et al. Estimation of dietary fat intake of Belgian pregnant women. Comparison of two methods. 2001 Ann. Nutr. Metab. pmid:11786650
Agostoni C et al. Long-chain polyunsaturated fatty acid concentrations in human hindmilk are constant throughout twelve months of lactation. 2001 Adv. Exp. Med. Biol. pmid:11787678
Demmelmair H et al. Investigation of long-chain polyunsaturated fatty acid metabolism in lactating women by means of stable isotope techniques. 2001 Adv. Exp. Med. Biol. pmid:11787680
Fidler N et al. Fat content and fatty acid composition of fresh, pasteurized, or sterilized human milk. 2001 Adv. Exp. Med. Biol. pmid:11787720
Gwak HS and Chun IK Effect of vehicles and enhancers on the in vitro skin penetration of aspalatone and its enzymatic degradation across rat skins. 2001 Arch. Pharm. Res. pmid:11794538
Azulay JP and Pouget J [Diabetic neuropathies]. 2001 Rev Prat pmid:11795122
Duffin KL et al. Lipid remodeling in mouse liver and plasma resulting from delta6 fatty acid desaturase inhibition. 2001 Lipids pmid:11795852
Schäfer K et al. Incorporation of dietary linoleic and conjugated linoleic acids and related effects on eggs of laying hens. 2001 Lipids pmid:11795854
Milne GL and Porter NA Separation and identification of phospholipid peroxidation products. 2001 Lipids pmid:11795860
Vargas F et al. In vitro antioxidant and photo-oxidant properties of dipyridamole. 2001 Nov-Dec Int. J. Toxicol. pmid:11797818
Wang CT et al. A calcium-independent phospholipase activity insensitive to bromoenol lactone mediates arachidonic acid release by lindane in rat myometrial cells. 2001 Life Sci. pmid:11798014
McCarthy-Beckett DO Dietary supplementation with conjugated linoleic acid does not improve nutritional status of tumor-bearing rats. 2002 Res Nurs Health pmid:11807919
Ulusu NN et al. Abietic acid inhibits lipoxygenase activity. 2002 Phytother Res pmid:11807975
Kawajiri H et al. Arachidonic and linoleic acid metabolism in mouse intestinal tissue: evidence for novel lipoxygenase activity. 2002 Arch. Biochem. Biophys. pmid:11811948
Mitchell LA et al. Linoleic acid, cis-epoxyoctadecenoic acids, and dihydroxyoctadecadienoic acids are toxic to Sf-21 cells in the absence of albumin. 2002 Toxicol. Lett. pmid:11814707
Raes K et al. The deposition of conjugated linoleic acids in eggs of laying hens fed diets varying in fat level and fatty acid profile. 2002 J. Nutr. pmid:11823576
Baron CP et al. Concentration effects in myoglobin-catalyzed peroxidation of linoleate. 2002 J. Agric. Food Chem. pmid:11829662
Joo ST et al. Effects of dietary conjugated linoleic acid on fatty acid composition, lipid oxidation, color, and water-holding capacity of pork loin. 2002 J. Anim. Sci. pmid:11831506
Minemoto Y et al. Oxidation of linoleic acid encapsulated with gum arabic or maltodextrin by spray-drying. 2002 Mar-Apr J Microencapsul pmid:11837973
Lemaitre RN et al. Cell membrane trans-fatty acids and the risk of primary cardiac arrest. 2002 Circulation pmid:11839624
Krutetskaia ZI et al. [Effect of arachidonic and other fatty acids on the intracellular calcium concentration and calcium signaling in peritoneal macrophages]. 2001 Tsitologiia pmid:11840781
Cahoon EB et al. Transgenic production of epoxy fatty acids by expression of a cytochrome P450 enzyme from Euphorbia lagascae seed. 2002 Plant Physiol. pmid:11842164
Ramirez DC and Gimenez MS Lipid modification in mouse peritoneal macrophages after chronic cadmium exposure. 2002 Toxicology pmid:11844611
Calder PC Conjugated linoleic acid in humans--reasons to be cheerful? 2002 Curr Opin Clin Nutr Metab Care pmid:11844976
Napolitano A et al. Reactions of hydro(pero)xy derivatives of polyunsaturated fatty acids/esters with nitrite ions under acidic conditions. Unusual nitrosative breakdown of methyl 13-hydro(pero)xyoctadeca-9,11-dienoate to a novel 4-nitro-2-oximinoalk-3-enal product. 2002 J. Org. Chem. pmid:11846653
Hernández A et al. In vivo activation of plasma membrane H(+)-ATPase hydrolytic activity by complex lipid-bound unsaturated fatty acids in Ustilago maydis. 2002 Eur. J. Biochem. pmid:11846803
Papanikolaou S and Aggelis G Lipid production by Yarrowia lipolytica growing on industrial glycerol in a single-stage continuous culture. 2002 Bioresour. Technol. pmid:11848376
Sheu MY et al. Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models. 2002 J. Invest. Dermatol. pmid:11851881
Pappas A et al. Metabolic fate and selective utilization of major fatty acids in human sebaceous gland. 2002 J. Invest. Dermatol. pmid:11851890
Reyes-De-Corcuera JI et al. Improved amperometric method for the rapid and quantitative measurement of lipoxygenase activity in vegetable tissue crude homogenates. 2002 J. Agric. Food Chem. pmid:11853470
Kohno H et al. Dietary conjugated linolenic acid inhibits azoxymethane-induced colonic aberrant crypt foci in rats. 2002 Jpn. J. Cancer Res. pmid:11856476
Demcakova E et al. Delta-6 desaturase activity and gene expression, tissue fatty acid profile and glucose turnover rate in hereditary hypertriglyceridemic rats. 2001 Endocr Regul pmid:11858764
Whitlock LA et al. Fish oil and extruded soybeans fed in combination increase conjugated linoleic acids in milk of dairy cows more than when fed separately. 2002 J. Dairy Sci. pmid:11860116
Zhu Y et al. [The inhibitory effect of CLA on mice forestomach neoplasia induced by B(a)P]. 2001 Zhonghua Yu Fang Yi Xue Za Zhi pmid:11860953
Lichtenstein AH et al. Efficacy of a Therapeutic Lifestyle Change/Step 2 diet in moderately hypercholesterolemic middle-aged and elderly female and male subjects. 2002 J. Lipid Res. pmid:11861668
Ishido E et al. Kinetic expression for the oxidation of linoleic and arachidonic acid esters in their mixed system. 2002 Biosci. Biotechnol. Biochem. pmid:11866122
Futakuchi M et al. Inhibition of conjugated fatty acids derived from safflower or perilla oil of induction and development of mammary tumors in rats induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). 2002 Cancer Lett. pmid:11867197
Sakurai T et al. Short-term efficacy of enteral nutrition in the treatment of active Crohn's disease: a randomized, controlled trial comparing nutrient formulas. 2002 Mar-Apr JPEN J Parenter Enteral Nutr pmid:11871742
van Dam RM et al. Dietary fat and meat intake in relation to risk of type 2 diabetes in men. 2002 Diabetes Care pmid:11874924
Elabbadi N et al. Regulation of phosphatidic acid phosphohydrolase 1 by fatty acids. 2002 Lipids pmid:11876265
Inouye K et al. Deodorization of soybean proteins by enzymatic and physicochemical treatments. 2002 J. Agric. Food Chem. pmid:11879052
Jardine D et al. Liquid chromatography-mass spectrometry (LC-MS) investigation of the thiobarbituric acid reactive substances (TBARS) reaction. 2002 J. Agric. Food Chem. pmid:11879064
Urquhart P et al. The effect of conjugated linoleic acid on arachidonic acid metabolism and eicosanoid production in human saphenous vein endothelial cells. 2002 Biochim. Biophys. Acta pmid:11880240
Evans M et al. Trans-10, cis-12 conjugated linoleic acid increases fatty acid oxidation in 3T3-L1 preadipocytes. 2002 J. Nutr. pmid:11880570
Svahn JC et al. Different quantities and quality of fat in milk products given to young children: effects on long chain polyunsaturated fatty acids and trans fatty acids in plasma. 2002 Acta Paediatr. pmid:11885548
Dichtl W et al. Linoleic acid-stimulated vascular adhesion molecule-1 expression in endothelial cells depends on nuclear factor-kappaB activation. 2002 Metab. Clin. Exp. pmid:11887169
Bolte MR et al. Feeding lambs high-oleate or high-linoleate safflower seeds differentially influences carcass fatty acid composition. 2002 J. Anim. Sci. pmid:11890397
Wiegand BR et al. Duration of feeding conjugated linoleic acid influences growth performance, carcass traits, and meat quality of finishing barrows. 2002 J. Anim. Sci. pmid:11890399
Beaulieu AD et al. Concentrations of conjugated linoleic acid (cis-9, trans-11-octadecadienoic acid) are not increased in tissue lipids of cattle fed a high-concentrate diet supplemented with soybean oil. 2002 J. Anim. Sci. pmid:11890424
Yang H et al. Effect of conjugated linoleic acid on the formation of spontaneous and PhIP-induced mutation in the colon and cecum of rats. 2002 Mutat. Res. pmid:11890945
Kawai T et al. Troglitazone ameliorates lipotoxicity in the beta cell line INS-1 expressing PPAR gamma. 2002 Diabetes Res. Clin. Pract. pmid:11891015
Roberts DC Nutrition and metabolism. 2002 Curr. Opin. Lipidol. pmid:11891423
Whigham LD et al. Decreased antigen-induced eicosanoid release in conjugated linoleic acid-fed guinea pigs. 2002 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:11893615
Pan J and Chung FL Formation of cyclic deoxyguanosine adducts from omega-3 and omega-6 polyunsaturated fatty acids under oxidative conditions. 2002 Chem. Res. Toxicol. pmid:11896684
King LM et al. Cloning of CYP2J2 gene and identification of functional polymorphisms. 2002 Mol. Pharmacol. pmid:11901223
Du M and Ahn DU Effect of dietary conjugated linoleic acid on the growth rate of live birds and on the abdominal fat content and quality of broiler meat. 2002 Poult. Sci. pmid:11902422
Galindo-Cuspinera V et al. Comparison of volatile compounds in water- and oil-soluble annatto (Bixa orellana L.) extracts. 2002 J. Agric. Food Chem. pmid:11902949
Kikuzaki H et al. Antioxidant properties of ferulic acid and its related compounds. 2002 J. Agric. Food Chem. pmid:11902973
Nakaya A et al. Helicobacter pylori alters n-6 fatty acid metabolism and prostaglandin E2 synthesis in rat gastric mucosal cells. 2001 J. Gastroenterol. Hepatol. pmid:11903735
Hurtado de Catalfo GE and de Gomez Dumm IN Polyunsaturated fatty acid biosynthesis from [1-14C]20:3 n-6 acid in rat cultured Sertoli cells. Linoleic acid effect. 2002 Int. J. Biochem. Cell Biol. pmid:11906823
Rong R et al. Dietary oxidized fatty acids may enhance intestinal apolipoprotein A-I production. 2002 J. Lipid Res. pmid:11907138
Masters N et al. Maternal supplementation with CLA decreases milk fat in humans. 2002 Lipids pmid:11908905
Hatano T et al. Proanthocyanidin glycosides and related polyphenols from cacao liquor and their antioxidant effects. 2002 Phytochemistry pmid:11909632
Rum P and Hornstra G The n-3 and n-6 polyunsaturated fatty acid composition of plasma phospholipids in pregnant women and their infants. relationship with maternal linoleic acid intake. 2002 Clin. Chem. Lab. Med. pmid:11916268
Ramanadham S et al. Delta6-, Stearoyl CoA-, and Delta5-desaturase enzymes are expressed in beta-cells and are altered by increases in exogenous PUFA concentrations. 2002 Biochim. Biophys. Acta pmid:11923099
Gravena C et al. Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans. 2002 J. Endocrinol. pmid:11927386
Boggia R et al. Classification and class-modeling of "Riviera Ligure" extra-virgin olive oil using chemical-physical parameters. 2002 J. Agric. Food Chem. pmid:11929311
Demmelmair H et al. Polyunsaturated fatty acid metabolism during lactation. 2001 World Rev Nutr Diet pmid:11935954
Sugano M Isomeric fatty acids: their physiological significance and health implications. 2001 World Rev Nutr Diet pmid:11935963
Abu-Ghazaleh AA et al. Feeding fish meal and extruded soybeans enhances the conjugated linoleic acid (CLA) content of milk. 2002 J. Dairy Sci. pmid:11949867
Nosjean O and Boutin JA Natural ligands of PPARgamma: are prostaglandin J(2) derivatives really playing the part? 2002 Cell. Signal. pmid:11955950
Yamasaki M et al. Effect of dietary conjugated linoleic acid on the in vivo growth of rat hepatoma dRLh-84. 2001 Nutr Cancer pmid:11962249
Tischendorf F et al. Influence of a conjugated linoleic acid mixture on growth, organ weights, carcass traits and meat quality in growing pigs. 2002 J Anim Physiol Anim Nutr (Berl) pmid:11972681
Park CW et al. Inclusion complex of conjugated linoleic acid (CLA) with cyclodextrins. 2002 J. Agric. Food Chem. pmid:11982428
Hung CY and Yen GC Antioxidant activity of phenolic compounds isolated from Mesona procumbens Hemsl. 2002 J. Agric. Food Chem. pmid:11982431
Terpstra AH et al. The decrease in body fat in mice fed conjugated linoleic acid is due to increases in energy expenditure and energy loss in the excreta. 2002 J. Nutr. pmid:11983818
Yaylayan VA et al. MAP: microwave-assisted extraction of cockroaches. 2002 Nat Prod Lett pmid:11990429
Stepień K et al. Peroxynitrite mediated linoleic acid oxidation and tyrosine nitration in the presence of synthetic neuromelanins. 2000 Acta Biochim. Pol. pmid:11996116
Fremann D et al. Dietary conjugated linoleic acid (CLA) intake assessment and possible biomarkers of CLA intake in young women. 2002 Public Health Nutr pmid:12001981
Corino C et al. Influence of dietary conjugated linoleic acid on growth, meat quality, lipogenesis, plasma leptin and physiological variables of lipid metabolism in rabbits. 2002 J. Anim. Sci. pmid:12002308
Madron MS et al. Effect of extruded full-fat soybeans on conjugated linoleic acid content of intramuscular, intermuscular, and subcutaneous fat in beef steers. 2002 J. Anim. Sci. pmid:12002322
Szentmihályi K et al. Rose hip (Rosa canina L.) oil obtained from waste hip seeds by different extraction methods. 2002 Bioresour. Technol. pmid:12003323
Ahmad A et al. A decrease in cell size accompanies a loss of docosahexaenoate in the rat hippocampus. 2002 Nutr Neurosci pmid:12004794
Parris N et al. Effect of endogenous triacylglycerol hydrolysates on the mechanical properties of Zein films from ground corn. 2002 J. Agric. Food Chem. pmid:12010002