(10e,12z)-octadeca-10,12-dienoic acid

(10e,12z)-octadeca-10,12-dienoic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 623 references associated with (10e,12z)-octadeca-10,12-dienoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for (10e,12z)-octadeca-10,12-dienoic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (10e,12z)-octadeca-10,12-dienoic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Total 1

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with (10e,12z)-octadeca-10,12-dienoic acid

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Authors Title Published Journal PubMed Link
Pini M et al. Adipose tissue adaptive response to trans-10,cis-12-conjugated linoleic acid engages alternatively activated M2 macrophages. 2016 FASEB J. pmid:26362817
Stefanson A et al. Feeding butter with elevated content of trans-10, cis-12 conjugated linoleic acid to lean rats does not impair glucose tolerance or muscle insulin response. 2014 Lipids Health Dis pmid:24956949
Huebner SM et al. Dietary trans-10,cis-12 CLA reduces murine collagen-induced arthritis in a dose-dependent manner. 2014 J. Nutr. pmid:24285692
Khelashvili G et al. Molecular origins of bending rigidity in lipids with isolated and conjugated double bonds: the effect of cholesterol. 2014 Chem. Phys. Lipids pmid:24394210
Prates EG et al. Fat area and lipid droplet morphology of porcine oocytes during in vitro maturation with trans-10, cis-12 conjugated linoleic acid and forskolin. 2013 Animal pmid:23098362
Bergamo P et al. RedOx status, proteasome and APEH: insights into anticancer mechanisms of t10,c12-conjugated linoleic acid isomer on A375 melanoma cells. 2013 PLoS ONE pmid:24260504
den Hartigh LJ et al. 10E,12Z-conjugated linoleic acid impairs adipocyte triglyceride storage by enhancing fatty acid oxidation, lipolysis, and mitochondrial reactive oxygen species. 2013 J. Lipid Res. pmid:23956445
Prates EG et al. Fatty acid composition of porcine cumulus oocyte complexes (COC) during maturation: effect of the lipid modulators trans-10, cis-12 conjugated linoleic acid (t10,c12 CLA) and forskolin. 2013 In Vitro Cell. Dev. Biol. Anim. pmid:23645468
Oraldi M et al. CLA reduces inflammatory mediators from A427 human lung cancer cells and A427 conditioned medium promotes differentiation of C2C12 murine muscle cells. 2013 Lipids pmid:23129255
Kadegowda AK et al. Inhibition of stearoyl-CoA desaturase 1 reduces lipogenesis in primary bovine adipocytes. 2013 Lipids pmid:23929455
Reardon M et al. Oleic acid attenuates trans-10,cis-12 conjugated linoleic acid-mediated inflammatory gene expression in human adipocytes. 2012 Lipids pmid:22941440
Zhang B et al. De novo synthesis of trans-10, cis-12 conjugated linoleic acid in oleaginous yeast Yarrowia lipolytica. 2012 Microb. Cell Fact. pmid:22545818
Berryhill GE et al. Diet-induced metabolic change induces estrogen-independent allometric mammary growth. 2012 Proc. Natl. Acad. Sci. U.S.A. pmid:22988119
Hutchinson IA et al. The effect of strategic supplementation with trans-10,cis-12 conjugated linoleic acid on the milk production, estrous cycle characteristics, and reproductive performance of lactating dairy cattle. 2012 J. Dairy Sci. pmid:22541471
Liu X et al. High dose trans-10,cis-12 CLA increases lean body mass in hamsters, but elevates levels of plasma lipids and liver enzyme biomarkers. 2012 Lipids pmid:22038709
Belda BJ et al. The dietary fatty acid 10E12Z-CLA induces epiregulin expression through COX-2 dependent PGF(2α) synthesis in adipocytes. 2012 Prostaglandins Other Lipid Mediat. pmid:22583689
Wang H et al. Isomer-specific effects of conjugated linoleic acid on proliferative activity of cultured neural progenitor cells. 2011 Mol. Cell. Biochem. pmid:21681414
Martinez K et al. JNK inhibition by SP600125 attenuates trans-10, cis-12 conjugated linoleic acid-mediated regulation of inflammatory and lipogenic gene expression. 2011 Lipids pmid:21744278
Rahman MM et al. t10c12-CLA maintains higher bone mineral density during aging by modulating osteoclastogenesis and bone marrow adiposity. 2011 J. Cell. Physiol. pmid:21660964
Maxin G et al. Combined effects of trans-10,cis-12 conjugated linoleic acid, propionate, and acetate on milk fat yield and composition in dairy cows. 2011 J. Dairy Sci. pmid:21426996