| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
Total
1
(10e,12z)-octadeca-10,12-dienoic acid
(10e,12z)-octadeca-10,12-dienoic acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 623 references associated with (10e,12z)-octadeca-10,12-dienoic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for (10e,12z)-octadeca-10,12-dienoic acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (10e,12z)-octadeca-10,12-dienoic acid
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with (10e,12z)-octadeca-10,12-dienoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pini M et al. | Adipose tissue adaptive response to trans-10,cis-12-conjugated linoleic acid engages alternatively activated M2 macrophages. | 2016 | FASEB J. | pmid:26362817 |
| Stefanson A et al. | Feeding butter with elevated content of trans-10, cis-12 conjugated linoleic acid to lean rats does not impair glucose tolerance or muscle insulin response. | 2014 | Lipids Health Dis | pmid:24956949 |
| Huebner SM et al. | Dietary trans-10,cis-12 CLA reduces murine collagen-induced arthritis in a dose-dependent manner. | 2014 | J. Nutr. | pmid:24285692 |
| Khelashvili G et al. | Molecular origins of bending rigidity in lipids with isolated and conjugated double bonds: the effect of cholesterol. | 2014 | Chem. Phys. Lipids | pmid:24394210 |
| Prates EG et al. | Fat area and lipid droplet morphology of porcine oocytes during in vitro maturation with trans-10, cis-12 conjugated linoleic acid and forskolin. | 2013 | Animal | pmid:23098362 |
| Bergamo P et al. | RedOx status, proteasome and APEH: insights into anticancer mechanisms of t10,c12-conjugated linoleic acid isomer on A375 melanoma cells. | 2013 | PLoS ONE | pmid:24260504 |
| den Hartigh LJ et al. | 10E,12Z-conjugated linoleic acid impairs adipocyte triglyceride storage by enhancing fatty acid oxidation, lipolysis, and mitochondrial reactive oxygen species. | 2013 | J. Lipid Res. | pmid:23956445 |
| Prates EG et al. | Fatty acid composition of porcine cumulus oocyte complexes (COC) during maturation: effect of the lipid modulators trans-10, cis-12 conjugated linoleic acid (t10,c12 CLA) and forskolin. | 2013 | In Vitro Cell. Dev. Biol. Anim. | pmid:23645468 |
| Oraldi M et al. | CLA reduces inflammatory mediators from A427 human lung cancer cells and A427 conditioned medium promotes differentiation of C2C12 murine muscle cells. | 2013 | Lipids | pmid:23129255 |
| Kadegowda AK et al. | Inhibition of stearoyl-CoA desaturase 1 reduces lipogenesis in primary bovine adipocytes. | 2013 | Lipids | pmid:23929455 |
| Reardon M et al. | Oleic acid attenuates trans-10,cis-12 conjugated linoleic acid-mediated inflammatory gene expression in human adipocytes. | 2012 | Lipids | pmid:22941440 |
| Zhang B et al. | De novo synthesis of trans-10, cis-12 conjugated linoleic acid in oleaginous yeast Yarrowia lipolytica. | 2012 | Microb. Cell Fact. | pmid:22545818 |
| Berryhill GE et al. | Diet-induced metabolic change induces estrogen-independent allometric mammary growth. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22988119 |
| Hutchinson IA et al. | The effect of strategic supplementation with trans-10,cis-12 conjugated linoleic acid on the milk production, estrous cycle characteristics, and reproductive performance of lactating dairy cattle. | 2012 | J. Dairy Sci. | pmid:22541471 |
| Liu X et al. | High dose trans-10,cis-12 CLA increases lean body mass in hamsters, but elevates levels of plasma lipids and liver enzyme biomarkers. | 2012 | Lipids | pmid:22038709 |
| Belda BJ et al. | The dietary fatty acid 10E12Z-CLA induces epiregulin expression through COX-2 dependent PGF(2α) synthesis in adipocytes. | 2012 | Prostaglandins Other Lipid Mediat. | pmid:22583689 |
| Abramson HN | The lipogenesis pathway as a cancer target. | 2011 | J. Med. Chem. | pmid:21726077 |
| Sato K et al. | The change in conjugated linoleic acid concentration in blood of Japanese fed a conjugated linoleic acid diet. | 2011 | J. Nutr. Sci. Vitaminol. | pmid:22293214 |
| Wang H et al. | Isomer-specific effects of conjugated linoleic acid on proliferative activity of cultured neural progenitor cells. | 2011 | Mol. Cell. Biochem. | pmid:21681414 |
| Hsu YC and Ip MM | Conjugated linoleic acid-induced apoptosis in mouse mammary tumor cells is mediated by both G protein coupled receptor-dependent activation of the AMP-activated protein kinase pathway and by oxidative stress. | 2011 | Cell. Signal. | pmid:21821121 |
| Martinez K et al. | JNK inhibition by SP600125 attenuates trans-10, cis-12 conjugated linoleic acid-mediated regulation of inflammatory and lipogenic gene expression. | 2011 | Lipids | pmid:21744278 |
| Rahman MM et al. | t10c12-CLA maintains higher bone mineral density during aging by modulating osteoclastogenesis and bone marrow adiposity. | 2011 | J. Cell. Physiol. | pmid:21660964 |
| Maxin G et al. | Combined effects of trans-10,cis-12 conjugated linoleic acid, propionate, and acetate on milk fat yield and composition in dairy cows. | 2011 | J. Dairy Sci. | pmid:21426996 |
| Tamura S et al. | Unprecedented NES non-antagonistic inhibitor for nuclear export of Rev from Sida cordifolia. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20176483 |
| Anadón A et al. | Acute oral safety study of dairy fat rich in trans-10 C18:1 versus vaccenic plus conjugated linoleic acid in rats. | 2010 | Food Chem. Toxicol. | pmid:19932730 |
| Maxin G et al. | Additive effects of trans-10, cis-12 conjugated linoleic acid and propionic acid on milk fat content and composition in dairy cows. | 2010 | J. Dairy Res. | pmid:20482933 |
| Sinclair LA et al. | A supplement containing trans-10, cis-12 conjugated linoleic acid reduces milk fat yield but does not alter organ weight or body fat deposition in lactating ewes. | 2010 | J. Nutr. | pmid:20861215 |
| Jaudszus A et al. | Trans-10,cis-12-CLA-caused lipodystrophy is associated with profound changes of fatty acid profiles of liver, white adipose tissue and erythrocytes in mice: possible link to tissue-specific alterations of fatty acid desaturation. | 2010 | Ann. Nutr. Metab. | pmid:20924169 |
| Foote MR et al. | t10,c12-CLA decreases adiposity in peripubertal mice without dose-related detrimental effects on mammary development, inflammation status, and metabolism. | 2010 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:20844263 |
| Huebner SM et al. | Individual isomers of conjugated linoleic acid reduce inflammation associated with established collagen-induced arthritis in DBA/1 mice. | 2010 | J. Nutr. | pmid:20573944 |
| Martinez K et al. | trans-10,cis-12-Conjugated linoleic acid instigates inflammation in human adipocytes compared with preadipocytes. | 2010 | J. Biol. Chem. | pmid:20353947 |
| Ashwell MS et al. | Trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis. | 2010 | J. Nutr. Biochem. | pmid:19800780 |
| Zhai JJ et al. | Different mechanisms of cis-9,trans-11- and trans-10,cis-12- conjugated linoleic acid affecting lipid metabolism in 3T3-L1 cells. | 2010 | J. Nutr. Biochem. | pmid:20138494 |
| Navarro MA et al. | Trans-10,cis-12-CLA dysregulate lipid and glucose metabolism and induce hepatic NR4A receptors. | 2010 | Front Biosci (Elite Ed) | pmid:20036857 |
| Martins SV et al. | Serum adipokine profile and fatty acid composition of adipose tissues are affected by conjugated linoleic acid and saturated fat diets in obese Zucker rats. | 2010 | Br. J. Nutr. | pmid:19878618 |
| Gutowska I et al. | Blood arachidonic acid and HDL cholesterol influence the phagocytic abilities of human monocytes/macrophages. | 2010 | Ann. Nutr. Metab. | pmid:21063085 |
| Jourdan T et al. | Liver carbohydrate and lipid metabolism of insulin-deficient mice is altered by trans-10, cis-12 conjugated linoleic acid. | 2009 | J. Nutr. | pmid:19692528 |
| Flowers M and Thompson PA | t10c12 conjugated linoleic acid suppresses HER2 protein and enhances apoptosis in SKBr3 breast cancer cells: possible role of COX2. | 2009 | PLoS ONE | pmid:19399184 |
| Harvatine KJ et al. | Expression of enzymes and key regulators of lipid synthesis is upregulated in adipose tissue during CLA-induced milk fat depression in dairy cows. | 2009 | J. Nutr. | pmid:19211829 |
| Goedecke JH et al. | Conjugated linoleic acid isomers, t10c12 and c9t11, are differentially incorporated into adipose tissue and skeletal muscle in humans. | 2009 | Lipids | pmid:19851798 |
| Navarro V et al. | A multi-gene analysis strategy identifies metabolic pathways targeted by trans-10, cis-12-conjugated linoleic acid in the liver of hamsters. | 2009 | Br. J. Nutr. | pmid:19216830 |
| Hur S et al. | Effects of trans-10,cis-12 conjugated linoleic acid on body composition in genetically obese mice. | 2009 | J Med Food | pmid:19298196 |
| Tholstrup T et al. | An oil mixture with trans-10, cis-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in postmenopausal women. | 2008 | J. Nutr. | pmid:18641189 |
| Ringseis R et al. | Conjugated linoleic acid isomers inhibit platelet-derived growth factor-induced NF-kappaB transactivation and collagen formation in human vascular smooth muscle cells. | 2008 | Eur J Nutr | pmid:18264811 |
| Meng X et al. | t10,c12-Conjugated linoleic acid stimulates mammary tumor progression in Her2/ErbB2 mice through activation of both proliferative and survival pathways. | 2008 | Carcinogenesis | pmid:18339686 |
| Kennedy A et al. | Trans-10, cis-12 conjugated linoleic acid antagonizes ligand-dependent PPARgamma activity in primary cultures of human adipocytes. | 2008 | J. Nutr. | pmid:18287349 |
| Ou L et al. | Apoptosis induced by t10,c12-conjugated linoleic acid is mediated by an atypical endoplasmic reticulum stress response. | 2008 | J. Lipid Res. | pmid:18263853 |
| Yun HS et al. | Cytotoxic effects of the conjugated linoleic acid isomers t10c12, c9t11-CLA and mixed form on rat hepatic stellate cells and CCl4-induced hepatic fibrosis. | 2008 | J. Nutr. Biochem. | pmid:17869086 |
| Lee K et al. | Antiobesity effect of trans-10,cis-12-conjugated linoleic acid-producing Lactobacillus plantarum PL62 on diet-induced obese mice. | 2007 | J. Appl. Microbiol. | pmid:17897219 |
| Rosberg-Cody E et al. | Heterologous expression of linoleic acid isomerase from Propionibacterium acnes and anti-proliferative activity of recombinant trans-10, cis-12 conjugated linoleic acid. | 2007 | Microbiology (Reading, Engl.) | pmid:17660413 |