| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Alcoholism | D000437 | 27 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Ascorbic Acid Deficiency | D001206 | 9 associated lipids |
| Back Pain | D001416 | 5 associated lipids |
| Bacteriuria | D001437 | 7 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Carcinoma 256, Walker | D002279 | 22 associated lipids |
| Cardiovascular Diseases | D002318 | 24 associated lipids |
| Carpal Tunnel Syndrome | D002349 | 3 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rice TW et al. | Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury. | 2011 | JAMA | pmid:21976613 |
| Felbinger TW et al. | Supplementation in acute lung injury. | 2012 | JAMA | pmid:22235078 |
| Bistrian BR | Supplementation in acute lung injury. | 2012 | JAMA | pmid:22235079 |
| König K et al. | Supplementation in acute lung injury. | 2012 | JAMA | pmid:22235080 |
| Schellhammer PF | Intravesical chemotherapy with gamma linolenic acid becomes a reality. | 1998 | J. Urol. | pmid:9817299 |
| Solomon LZ et al. | Intravesical chemotherapy with gamma linolenic acid becomes a realistic prospect in serum-free applications: in vitro cytotoxicity and systemic absorption studies. | 1998 | J. Urol. | pmid:9817384 |
| Rodgers A et al. | Evening primrose oil supplementation increases citraturia and decreases other urinary risk factors for calcium oxalate urolithiasis. | 2009 | J. Urol. | pmid:19846138 |
| Gillis RC et al. | Eicosapentaenoic acid and gamma-linolenic acid induce apoptosis in HL-60 cells. | 2002 | J. Surg. Res. | pmid:12384078 |
| Pham H and Ziboh VA | 5 alpha-reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids. | 2002 | J. Steroid Biochem. Mol. Biol. | pmid:12589947 |
| Tate G et al. | Suppression of acute and chronic inflammation by dietary gamma linolenic acid. | 1989 | J. Rheumatol. | pmid:2550629 |
| Yadav S et al. | Comparative efficacy of alpha-linolenic acid and gamma-linolenic acid to attenuate valproic acid-induced autism-like features. | 2017 | J. Physiol. Biochem. | pmid:27878518 |
| Matta JA et al. | TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. | 2007 | J. Physiol. (Lond.) | pmid:17038422 |
| Yu Z et al. | Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acid. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16421287 |
| Dines KC et al. | Comparison of the effects of evening primrose oil and triglycerides containing gamma-linolenic acid on nerve conduction and blood flow in diabetic rats. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7714803 |
| Hayashi Y et al. | Anticancer activity of free gamma-linolenic acid on AH-109A rat hepatoma cells and the effect of serum albumin on anticancer activity of gamma-linolenic acid in vitro. | 1990 | J. Pharmacobio-dyn. | pmid:1965510 |
| Ho S et al. | In-vitro transcutaneous delivery of tamoxifen and gamma-linolenic acid from borage oil containing ethanol and 1,8-cineole. | 2004 | J. Pharm. Pharmacol. | pmid:15525441 |
| Hørby Jørgensen M et al. | Effect of formula supplemented with docosahexaenoic acid and gamma-linolenic acid on fatty acid status and visual acuity in term infants. | 1998 | J. Pediatr. Gastroenterol. Nutr. | pmid:9552137 |
| Cartwright-Shamoon JM et al. | A complex biochemical modulation of intestinal ion transport in rats fed on high-fat diets. | 1995 | J. Pediatr. Gastroenterol. Nutr. | pmid:7884616 |
| Decsi T et al. | Effect of type of early infant feeding on fatty acid composition of plasma lipid classes in full-term infants during the second 6 months of life. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:10817286 |
| Van Biervliet JP et al. | Serum cholesterol, cholesteryl ester, and high-density lipoprotein development in newborn infants: response to formulas supplemented with cholesterol and gamma-linolenic acid. | 1992 | J. Pediatr. | pmid:1313864 |
| Rubin M et al. | Effect of three intravenously administered fat emulsions containing different concentrations of fatty acids on the plasma fatty acid composition of premature infants. | 1994 | J. Pediatr. | pmid:7931881 |
| Wedig KE and Whitsett JA | Down the primrose path: petechiae in a neonate exposed to herbal remedy for parturition. | 2008 | J. Pediatr. | pmid:18154917 |
| Maaswinkel-Mooij PD et al. | Unsuccessful dietary treatment of Sjögren-Larsson syndrome. | 1994 | J. Pediatr. | pmid:8176565 |
| Fewtrell MS et al. | Randomized, double-blind trial of long-chain polyunsaturated fatty acid supplementation with fish oil and borage oil in preterm infants. | 2004 | J. Pediatr. | pmid:15069395 |
| Hrastinger A et al. | Is there clinical evidence supporting the use of botanical dietary supplements in children? | 2005 | J. Pediatr. | pmid:15756210 |
| Fauconnot L and Buist PH | Gamma-linolenic acid biosynthesis: cryptoregiochemistry of delta6 desaturation. | 2001 | J. Org. Chem. | pmid:11312950 |
| Tahvonen RL et al. | Black currant seed oil and fish oil supplements differ in their effects on fatty acid profiles of plasma lipids, and concentrations of serum total and lipoprotein lipids, plasma glucose and insulin. | 2005 | J. Nutr. Biochem. | pmid:15936647 |
| Fan YY et al. | Dietary gamma-linolenic acid enhances mouse macrophage-derived prostaglandin E1 which inhibits vascular smooth muscle cell proliferation. | 1997 | J. Nutr. | pmid:9278557 |
| Fan YY and Chapkin RS | Mouse peritoneal macrophage prostaglandin E1 synthesis is altered by dietary gamma-linolenic acid. | 1992 | J. Nutr. | pmid:1322453 |
| Johnson MM et al. | Dietary supplementation with gamma-linolenic acid alters fatty acid content and eicosanoid production in healthy humans. | 1997 | J. Nutr. | pmid:9237935 |
| Chapkin RS and Carmichael SL | Effect of dietary blackcurrant seed oil on mouse macrophage subclasses of choline and ethanolamine glycerophospholipids. | 1990 | J. Nutr. | pmid:1974284 |
| Barham JB et al. | Addition of eicosapentaenoic acid to gamma-linolenic acid-supplemented diets prevents serum arachidonic acid accumulation in humans. | 2000 | J. Nutr. | pmid:10917903 |
| Fan YY and Chapkin RS | Importance of dietary gamma-linolenic acid in human health and nutrition. | 1998 | J. Nutr. | pmid:9732298 |
| Takada R et al. | Dietary gamma-linolenic acid-enriched oil reduces body fat content and induces liver enzyme activities relating to fatty acid beta-oxidation in rats. | 1994 | J. Nutr. | pmid:8145067 |
| Fan YY et al. | Dietary lipid source alters murine macrophage/vascular smooth muscle cell interactions in vitro. | 1996 | J. Nutr. | pmid:8814195 |
| Tso P et al. | Intestinal absorption and lymphatic transport of a high gamma-linolenic acid canola oil in lymph fistula Sprague-Dawley rats. | 2002 | J. Nutr. | pmid:11823581 |
| Tsimaratos M et al. | Gamma-linolenic acid restores renal medullary thick ascending limb Na(+),K(+)-ATPase activity in diabetic rats. | 2001 | J. Nutr. | pmid:11739860 |
| Fan YY et al. | Dietary gamma-linolenic acid suppresses aortic smooth muscle cell proliferation and modifies atherosclerotic lesions in apolipoprotein E knockout mice. | 2001 | J. Nutr. | pmid:11385052 |
| Thies F et al. | Dietary supplementation with gamma-linolenic acid or fish oil decreases T lymphocyte proliferation in healthy older humans. | 2001 | J. Nutr. | pmid:11435508 |
| Pitel S et al. | At low doses, a gamma-linolenic acid-lipoic acid conjugate is more effective than docosahexaenoic acid-enriched phospholipids in preventing neuropathy in diabetic rats. | 2007 | J. Nutr. | pmid:17237313 |
| Frenoux JM et al. | A polyunsaturated fatty acid diet lowers blood pressure and improves antioxidant status in spontaneously hypertensive rats. | 2001 | J. Nutr. | pmid:11208936 |
| Schirmer MA and Phinney SD | Gamma-linolenate reduces weight regain in formerly obese humans. | 2007 | J. Nutr. | pmid:17513402 |
| Petrik MB et al. | Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. | 2000 | J. Nutr. | pmid:11015469 |
| Chapkin RS et al. | Dietary influences of evening primrose and fish oil on the skin of essential fatty acid-deficient guinea pigs. | 1987 | J. Nutr. | pmid:3625311 |
| Chung S et al. | Gamma-linolenic acid in borage oil reverses epidermal hyperproliferation in guinea pigs. | 2002 | J. Nutr. | pmid:12368400 |
| Song C et al. | Long-chain polyunsaturated fatty acids modulate interleukin-1beta-induced changes in behavior, monoaminergic neurotransmitters, and brain inflammation in rats. | 2008 | J. Nutr. | pmid:18424607 |
| Bell HS et al. | Effects of N-6 essential fatty acids on glioma invasion and growth: experimental studies with glioma spheroids in collagen gels. | 1999 | J. Neurosurg. | pmid:10584845 |
| Biessels GJ et al. | The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. | 2001 | J. Neurol. Sci. | pmid:11137514 |
| Julu PO and Mutamba A | Comparison of short-term effects of insulin and essential fatty acids on the slowed nerve conduction of streptozotocin diabetes in rats. | 1991 | J. Neurol. Sci. | pmid:1663993 |
| Likhodii SS and Cunnane SC | Uptake of 13C-tracer arachidonate and gamma-linolenate by the brain and liver of the suckling rat observed using 13C-NMR. | 1999 | J. Neurochem. | pmid:10349866 |