Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Jiang WG et al. | gamma-Linolenic acid blocks cell cycle progression by regulating phosphorylation of p27kip1 and p57kip2 and their interactions with other cycle regulators in cancer cells. | 1998 | Int. J. Oncol. | pmid:9683802 |
Menendez JA et al. | Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis. | 2004 | Int. J. Oncol. | pmid:15138577 |
Rahbeeni F et al. | The effect of evening primrose oil on the radiation response and blood flow of mouse normal and tumour tissue. | 2000 | Int. J. Radiat. Biol. | pmid:10902742 |
Hopewell JW et al. | Amelioration of both early and late radiation-induced damage to pig skin by essential fatty acids. | 1994 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:7961020 |
Aragona P et al. | Systemic omega-6 essential fatty acid treatment and pge1 tear content in Sjögren's syndrome patients. | 2005 | Invest. Ophthalmol. Vis. Sci. | pmid:16303936 |
Prencipe M et al. | Naudicelle and platelet reactivity in TIA patients. | 1982 | Ital J Neurol Sci | pmid:7166485 |
Halat KM and Dennehy CE | Botanicals and dietary supplements in diabetic peripheral neuropathy. | 2003 Jan-Feb | J Am Board Fam Pract | pmid:12583650 |
Horner NK and Lampe JW | Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness. | 2000 | J Am Diet Assoc | pmid:11103660 |
McCollum JR | FDA alert on evening primrose oil. | 1989 | J Am Diet Assoc | pmid:2542387 |
OtleÅŸ S and Pire R | Fatty acid composition of Chlorella and Spirulina microalgae species. | 2001 Nov-Dec | J AOAC Int | pmid:11767135 |
Singh NK et al. | Essential fatty acids and cancer with particular reference to Hodgkin's disease. | 1987 | J Assoc Physicians India | pmid:3693269 |
Das UN et al. | Beneficial effect of essential fatty acids in cirrhosis of the liver. | 1987 | J Assoc Physicians India | pmid:3693270 |
Giamarellos-Bourboulis EJ et al. | Do Escherichia coli susceptibilities to various antibiotics decrease in the presence of polyunsaturated fatty acids? A preliminary report. | 1994 | J Chemother | pmid:8071677 |
Arnold LE et al. | Does zinc moderate essential fatty acid and amphetamine treatment of attention-deficit/hyperactivity disorder? | 2000 | J Child Adolesc Psychopharmacol | pmid:10933121 |
Sýkora J et al. | High-performance liquid chromatography with nuclear magnetic resonance detection--A method for quantification of alpha- and gamma-linolenic acids in their mixtures with free fatty acids. | 2007 | J Chromatogr A | pmid:17157864 |
LÃsa M et al. | Comparison of various types of stationary phases in non-aqueous reversed-phase high-performance liquid chromatography-mass spectrometry of glycerolipids in blackcurrant oil and its enzymatic hydrolysis mixture. | 2009 | J Chromatogr A | pmid:19837411 |
Itoh S et al. | Antineoplastic effects of gamma linolenic Acid on hepatocellular carcinoma cell lines. | 2010 | J Clin Biochem Nutr | pmid:20664735 |
Patel GK and Logan RA | Golden nail pigmentation. | 2002 | J Dermatolog Treat | pmid:12006139 |
Julu PO | Essential fatty acids prevent slowed nerve conduction in streptozotocin diabetic rats. | 1988 Oct-Dec | J Diabet Complications | pmid:2853165 |
Park SO et al. | Gamma-linolenic acid egg production enriched with hemp seed oil and evening primrose oil in diet of laying hens. | 2014 | J Environ Biol | pmid:25004746 |
Montserrat-de la Paz S et al. | Long-chain fatty alcohols from evening primrose oil inhibit the inflammatory response in murine peritoneal macrophages. | 2014 | J Ethnopharmacol | pmid:24239848 |
Labruzzo BA et al. | Which complementary therapies can help patients with PMS? | 2009 | J Fam Pract | pmid:19874736 |
Seibel MM | Treating hot flushes without hormone replacement therapy. | 2003 | J Fam Pract | pmid:12681090 |
Deferne JL and Leeds AR | Resting blood pressure and cardiovascular reactivity to mental arithmetic in mild hypertensive males supplemented with blackcurrant seed oil. | 1996 | J Hum Hypertens | pmid:8895037 |
Cohen DA et al. | Impact of two pulmonary enteral formulations on nutritional indices and outcomes. | 2013 | J Hum Nutr Diet | pmid:23189938 |
Julu PO et al. | Endogenous cyclo-oxygenase substrates mediate the neuroactivity of evening primrose oil in rats. | 1996 | J Lipid Mediat Cell Signal | pmid:8925193 |
Julu PO | Latency of neuroactivity and optimum period of treatment with evening primrose oil in diabetic rats. | 1996 | J Lipid Mediat Cell Signal | pmid:8925199 |
Zaniewska A et al. | The activity of lysosomal exoglycosidases in serum of alcohol-dependent men supplemented with borage oil enriched with vitamin E. | 2009 | J Med Food | pmid:19735195 |
Lindmark L and Clough P | A 5-month open study with long-chain polyunsaturated fatty acids in dyslexia. | 2007 | J Med Food | pmid:18158838 |
Samuels R et al. | Hypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndrome. | 2002 | J Med Food | pmid:12487756 |
Al-Khamees WA et al. | Status epilepticus associated with borage oil ingestion. | 2011 | J Med Toxicol | pmid:21387119 |
Chan LW et al. | Microencapsulation of oils using sodium alginate. | 2000 Nov-Dec | J Microencapsul | pmid:11063422 |
Dove D and Johnson P | Oral evening primrose oil: its effect on length of pregnancy and selected intrapartum outcomes in low-risk nulliparous women. | 1999 May-Jun | J Nurse Midwifery | pmid:10380450 |
Ormerod LD et al. | Eicosanoid modulation and epithelial wound healing kinetics of the alkali-burned cornea. | 1992 | J Ocul Pharmacol | pmid:1328428 |
Dasgupta S and Bhattacharyya DK | Dietary effect of gamma-linolenic acid on the lipid profile of rat fed erucic acid rich oil. | 2007 | J Oleo Sci | pmid:17938547 |
Kawamura A et al. | Dietary supplementation of gamma-linolenic acid improves skin parameters in subjects with dry skin and mild atopic dermatitis. | 2011 | J Oleo Sci | pmid:22123240 |
Ruiz-Rodriguez A et al. | Recent trends in the advanced analysis of bioactive fatty acids. | 2010 | J Pharm Biomed Anal | pmid:19525080 |
Giamarellos-Bourboulis EJ et al. | Lipid peroxidation by Pseudomonas aeruginosa in the pathogenesis of nosocomial sepsis. | 2003 Jan-Mar | J Postgrad Med | pmid:12865564 |
Sutton GC | 'Too tired to go to the support group': a health needs assessment of myalgic encephalomyelitis. | 1996 | J Public Health Med | pmid:8887847 |
Wright S | Atopic eczema. | 1991 | J R Coll Physicians Lond | pmid:1920221 |
Gateley CA et al. | Drug treatments for mastalgia: 17 years experience in the Cardiff Mastalgia Clinic. | 1992 | J R Soc Med | pmid:1548647 |
Horrobin DF | The role of essential fatty acids and prostaglandins in the premenstrual syndrome. | 1983 | J Reprod Med | pmid:6350579 |
Puolakka J et al. | Biochemical and clinical effects of treating the premenstrual syndrome with prostaglandin synthesis precursors. | 1985 | J Reprod Med | pmid:3839018 |
Campbell EM et al. | Premenstrual symptoms in general practice patients. Prevalence and treatment. | 1997 | J Reprod Med | pmid:9350019 |
Williams JH | The use of gamma linolenic acid, linoleic acid and natural vitamin E for the treatment of multicentric lymphoma in two dogs. | 1988 | J S Afr Vet Assoc | pmid:2848946 |
Ghoreishi SM et al. | Separation of γ-linolenic and other polyunsaturated fatty acids from Boraginaceae via supercritical CO2. | 2011 | J Sep Sci | pmid:21246730 |
Krestnikova N et al. | JNK implication in adipocyte-like cell death induced by chemotherapeutic drug cisplatin. | 2015 | J Toxicol Sci | pmid:25560393 |
Seidel A et al. | The Influence of long-chain polyunsaturated fatty acids on total lipid fatty acid composition of a canine mastocytoma cell line. | 2005 | J Vet Med A Physiol Pathol Clin Med | pmid:15943605 |
Del Castillo ML et al. | Fatty acid content and juice characteristics in black currant (Ribes nigrum L.) genotypes. | 2004 | J. Agric. Food Chem. | pmid:14969555 |
Hamburger M et al. | Constituents in evening primrose oil with radical scavenging, cyclooxygenase, and neutrophil elastase inhibitory activities. | 2002 | J. Agric. Food Chem. | pmid:12236675 |