Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Papanikolaou N et al. | Effects of OKY-046 and nifedipine in cyclosporine-induced renal dysfunction in rats. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8951993 |
Dines KC et al. | Effectiveness of natural oils as sources of gamma-linolenic acid to correct peripheral nerve conduction velocity abnormalities in diabetic rats: modulation by thromboxane A2 inhibition. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8931113 |
Matsuo N et al. | Effects of gamma-linolenic acid and its positional isomer pinolenic acid on immune parameters of brown-Norway rats. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8951990 |
Glen AI et al. | Membrane fatty acids, niacin flushing and clinical parameters. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8888117 |
Cameron NE and Cotter MA | Comparison of the effects of ascorbyl gamma-linolenic acid and gamma-linolenic acid in the correction of neurovascular deficits in diabetic rats. | 1996 | Diabetologia | pmid:8877288 |
Awad AB et al. | The effect of unsaturated fatty acids on membrane composition and signal transduction in HT-29 human colon cancer cells. | 1996 | Cancer Lett. | pmid:8950205 |
Reddy AS and Thomas TL | Expression of a cyanobacterial delta 6-desaturase gene results in gamma-linolenic acid production in transgenic plants. | 1996 | Nat. Biotechnol. | pmid:9630958 |
Sadi AM et al. | Dietary effects of corn oil, oleic acid, perilla oil, and evening [corrected] primrose oil on plasma and hepatic lipid level and atherosclerosis in Japanese quail. | 1996 | Exp. Anim. | pmid:8689581 |
Huang Z et al. | Functional identification of the active-site nucleophile of the human 85-kDa cytosolic phospholipase A2. | 1996 | Biochemistry | pmid:8619991 |
Leaver HA et al. | Arachidonic acid activation of monocyte and neutrophil reactive oxygen in lung cancer patients undergoing pulmonary resection. | 1996 | Biologicals | pmid:9088546 |
Quoc KP and Pascaud M | Effects of dietary gamma-linolenic acid on the tissue phospholipid fatty acid composition and the synthesis of eicosanoids in rats. | 1996 | Ann. Nutr. Metab. | pmid:8773734 |
Hrelia S et al. | gamma-Linolenic acid supplementation can affect cancer cell proliferation via modification of fatty acid composition. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8753781 |
Fan YY et al. | Dietary lipid source alters murine macrophage/vascular smooth muscle cell interactions in vitro. | 1996 | J. Nutr. | pmid:8814195 |
Omawari N et al. | Deficient nitric oxide responsible for reduced nerve blood flow in diabetic rats: effects of L-NAME, L-arginine, sodium nitroprusside and evening primrose oil. | 1996 | Br. J. Pharmacol. | pmid:8733594 |
Sherrington EJ et al. | The effect of dietary lipid manipulation on the uptake of [3H]-triolein by tissues of the rat. | 1996 | Biochem. Soc. Trans. | pmid:8736833 |
Grant D et al. | The antioxidant activity of heparins. | 1996 | Biochem. Soc. Trans. | pmid:8736852 |
Stainforth JM et al. | Clinical aspects of the use of gamma linolenic acid in systemic sclerosis. | 1996 | Acta Derm. Venereol. | pmid:8740271 |
Budeiri D et al. | Is evening primrose oil of value in the treatment of premenstrual syndrome? | 1996 | Control Clin Trials | pmid:8721802 |
Each of the following has been shown to be effective for cyclical breast pain. | 1996 | Can Fam Physician | pmid:8704485 | |
Schöpf E et al. | [Gamma-linolenic acid in atopic patients?]. | 1996 | Med Monatsschr Pharm | pmid:8684312 |
Jiang WG et al. | Inhibition of neutrophil respiratory burst and cytokine priming by gamma-linolenic acid. | 1996 | Br J Surg | pmid:8689213 |
McCarty MF | Fish oil may impede tumour angiogenesis and invasiveness by down-regulating protein kinase C and modulating eicosanoid production. | 1996 | Med. Hypotheses | pmid:8692033 |
Ells GW et al. | Vitamin E blocks the cytotoxic effect of gamma-linolenic acid when administered as late as the time of onset of cell death--insight into the mechanism of fatty acid induced cytotoxicity. | 1996 | Cancer Lett. | pmid:8556710 |
Palombo JD et al. | Rapid modulation of lung and liver macrophage phospholipid fatty acids in endotoxemic rats by continuous enteral feeding with n-3 and gamma-linolenic fatty acids. | 1996 | Am. J. Clin. Nutr. | pmid:8561062 |
Chilton-Lopez ME et al. | Metabolism of gammalinolenic acid in human neutrophils. | 1996 | J. Immunol. | pmid:8609415 |
Redden PR et al. | Comparison of the grignard deacylation TLC and HPLC methods and high resolution 13C-NMR for the sn-2 positional analysis of triacylglycerols containing gamma-linolenic acid. | 1996 | Chem. Phys. Lipids | pmid:8907238 |
Julu PO et al. | Endogenous cyclo-oxygenase substrates mediate the neuroactivity of evening primrose oil in rats. | 1996 | J Lipid Mediat Cell Signal | pmid:8925193 |
Luthria DL and Sprecher H | Metabolism of deuterium-labeled linoleic, 6,9,12-octadecatrienoic, 8,11,14-eicosatrienoic, and arachidonic acids in the rat. | 1995 | J. Lipid Res. | pmid:8558078 |
Berth-Jones J et al. | Evening primrose oil and atopic eczema. | 1995 | Lancet | pmid:7861894 |
Morris GM et al. | Trophic effects of essential fatty acids on pig skin. | 1995 | Cell Prolif. | pmid:7893841 |
Murai A et al. | Role of dietary gamma-linolenic acid in liver lipid metabolism in Japanese quail. | 1995 | Br. Poult. Sci. | pmid:8746984 |
Murray MJ et al. | Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs. | 1995 | Am. J. Physiol. | pmid:8594921 |
Bell JG et al. | Diets rich in eicosapentaenoic acid and gamma-linolenic acid affect phospholipid fatty acid composition and production of prostaglandins E1, E2 and E3 in turbot (Scophthalmus maximus), a species deficient in delta 5 fatty acid desaturase. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8577782 |
Rothman D et al. | Botanical lipids: effects on inflammation, immune responses, and rheumatoid arthritis. | 1995 | Semin. Arthritis Rheum. | pmid:8578315 |
Koba K et al. | Distribution of plasma phosphatidylcholine molecular species in rabbits fed fish oil is modulated by dietary n-6 fatty acids. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8821127 |
Leichsenring M et al. | (n-6)-Fatty acids in plasma lipids of children with atopic bronchial asthma. | 1995 | Pediatr Allergy Immunol | pmid:8822394 |
Meehan E et al. | Influence of an n-6 polyunsaturated fatty acid-enriched diet on the development of tolerance during chronic ethanol administration in rats. | 1995 | Alcohol. Clin. Exp. Res. | pmid:8749808 |
Cartwright-Shamoon JM et al. | A complex biochemical modulation of intestinal ion transport in rats fed on high-fat diets. | 1995 | J. Pediatr. Gastroenterol. Nutr. | pmid:7884616 |
Karikó K et al. | Stimulatory effect of unsaturated fatty acids on the level of plasminogen activator inhibitor-1 mRNA in cultured human endothelial cells. | 1995 | FEBS Lett. | pmid:7890029 |
Rossetti RG et al. | Differential regulation of human T lymphocyte protein kinase C activity by unsaturated fatty acids. | 1995 | Clin. Immunol. Immunopathol. | pmid:7554442 |
Lindskov R and Petersen CS | [Oral gamma-linoleic acid (Epogam) in the treatment of atopic dermatitis]. | 1995 | Ugeskr. Laeg. | pmid:7483071 |
Hrelia S et al. | Essential fatty acid metabolism in cultured rat cardiomyocytes in response to either N-6 or N-3 fatty acid supplementation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7488075 |
Chajès V et al. | Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: relationship to peroxides and vitamin-E. | 1995 | Breast Cancer Res. Treat. | pmid:7579484 |
Larsson-Backström C et al. | Effects of dietary alpha- and gamma-linolenic acids on liver fatty acids, lipid metabolism, and survival in sepsis. | 1995 | Shock | pmid:7552772 |
Das UN et al. | Local application of gamma-linolenic acid in the treatment of human gliomas. | 1995 | Cancer Lett. | pmid:7634242 |
Kietzmann M | [Pharmacotherapeutic use of antipruritic drugs in skin diseases]. | 1995 | Tierarztl Prax | pmid:7545832 |
Claassen N et al. | Supplemented gamma-linolenic acid and eicosapentaenoic acid influence bone status in young male rats: effects on free urinary collagen crosslinks, total urinary hydroxyproline, and bone calcium content. | 1995 | Bone | pmid:7626328 |
Akahane N et al. | Antithrombotic activity of a symmetrical triglyceride with eicosapentaenoic acid and gamma-linolenic acid in guinea pig mesenteric microvasculature. | 1995 | Thromb. Res. | pmid:7660360 |
Jiang WG et al. | Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid. | 1995 | Br. J. Cancer | pmid:7710939 |
Jiang WG et al. | Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA). | 1995 | Cancer Res. | pmid:7585549 |