Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Abou-el-Ela SH et al. | Eicosanoid synthesis in 7,12-dimethylbenz(a)anthracene-induced mammary carcinomas in Sprague-Dawley rats fed primrose oil, menhaden oil or corn oil diet. | 1988 | Lipids | pmid:3143882 |
Belch JJ et al. | Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. | 1988 | Ann. Rheum. Dis. | pmid:2833184 |
Chaud M et al. | Gamma-linolenic acid improves the constancy of contractions in uteri from sprayed rats and is metabolized to prostaglandin E1 but not to bisenoic prostanoids. | 1988 | Prostaglandins | pmid:2836889 |
Wade AE et al. | Effect of 7,12-dimethylbenz(a)anthracene administration on hepatic drug metabolizing enzymes in female rats fed corn, primrose, and menhaden oils. | 1988 | Drug Nutr Interact | pmid:3149238 |
Darlington LG | Do diets rich in polyunsaturated fatty acids affect disease activity in rheumatoid arthritis? | 1988 | Ann. Rheum. Dis. | pmid:3281607 |
Barcelli UO et al. | A diet containing n-3 and n-6 fatty acids favorably alters the renal phospholipids, eicosanoid synthesis and plasma lipids in nephrotic rats. | 1988 | Lipids | pmid:3237005 |
Dib A and Carreau JP | Effects of gamma-linolenic acid supplementation on pregnant rats fed a zinc-deficient diet. | 1987 | Ann. Nutr. Metab. | pmid:2821872 |
Huang YS et al. | Protective effect of gamma-linolenic acid on aspirin-induced gastric hemorrhage in rats. | 1987 | Digestion | pmid:3030865 |
Horrobin DF | Essential fatty acids, prostaglandins, and alcoholism: an overview. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3032012 |
Meigel W et al. | [Additional oral therapy of atopic dermatitis with unsaturated fatty acids]. | 1987 | Z. Hautkr. | pmid:2894730 |
Fujiwara F et al. | Fatty acid modification of cultured neuroblastoma cells by gamma linolenic acid relevant to its antitumor effect. | 1987 | Prostaglandins Leukot Med | pmid:2829239 |
Van der Merwe CF et al. | Oral gamma-linolenic acid in 21 patients with untreatable malignancy. An ongoing pilot open clinical trial. | 1987 | Br J Clin Pract | pmid:2837264 |
Simpson LO | Pinch skin grafting or porcine dermis in venous ulcers. | 1987 | Br Med J (Clin Res Ed) | pmid:3109651 |
Nassar BA et al. | The influence of dietary marine oil (Polepa) and evening primrose oil (Efamol) on prostaglandin production by the rat mesenteric vasculature. | 1987 | Prostaglandins Leukot Med | pmid:3033691 |
McIllmurray MB and Turkie W | Controlled trial of gamma linolenic acid in Duke's C colorectal cancer. | 1987 | Br Med J (Clin Res Ed) | pmid:3036291 |
Huang YS and Horrobin DF | Sex differences in n-3 and n-6 fatty acid metabolism in EFA-depleted rats. | 1987 | Proc. Soc. Exp. Biol. Med. | pmid:3037555 |
el-Ela SH et al. | Effects of dietary primrose oil on mammary tumorigenesis induced by 7,12-dimethylbenz(a)anthracene. | 1987 | Lipids | pmid:3131611 |
Cunnane SC | Hepatic triacylglycerol accumulation induced by ethanol and carbon tetrachloride: interactions with essential fatty acids and prostaglandins. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3032013 |
Ziboh VA and Chapkin RS | Biologic significance of polyunsaturated fatty acids in the skin. | 1987 | Arch Dermatol | pmid:3688908 |
Singh NK et al. | Essential fatty acids and cancer with particular reference to Hodgkin's disease. | 1987 | J Assoc Physicians India | pmid:3693269 |
Das UN et al. | Beneficial effect of essential fatty acids in cirrhosis of the liver. | 1987 | J Assoc Physicians India | pmid:3693270 |
Papanikolaou N | Alteration of mercuric chloride-induced autoimmune glomerulonephritis in brown-Norway rats by herring oil, evening primrose oil and OKY-046 a selective TXA-synthetase inhibitor. | 1987 | Prostaglandins Leukot Med | pmid:3475724 |
Papanikolaou N et al. | Effect of thromboxane A2-synthetase inhibitor OKY-046 and evening primrose oil (Efamol) on mercuric chloride induced autoimmune glomerulonephritis in Brown-Norway rats. | 1987 | Prog. Clin. Biol. Res. | pmid:3671393 |
Guenther L and Wexler D | Efamol in the treatment of atopic dermatitis. | 1987 | J. Am. Acad. Dermatol. | pmid:3680673 |
Glen I et al. | The role of essential fatty acids in alcohol dependence and tissue damage. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3551662 |
Bordoni A et al. | [Treatment of premenstrual syndrome with essential fatty acids (evening primrose oil)]. | 1987 | G Clin Med | pmid:3609594 |
Takahashi R et al. | Effect of different ratios of dietary N-6 and N-3 fatty acids on fatty acid composition, prostaglandin formation and platelet aggregation in the rat. | 1987 | Thromb. Res. | pmid:3660347 |
Chapkin RS et al. | Dietary influences of evening primrose and fish oil on the skin of essential fatty acid-deficient guinea pigs. | 1987 | J. Nutr. | pmid:3625311 |
Schalin-Karrila M et al. | Evening primrose oil in the treatment of atopic eczema: effect on clinical status, plasma phospholipid fatty acids and circulating blood prostaglandins. | 1987 | Br. J. Dermatol. | pmid:3307886 |
Skogh M | Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids) | 1986 | J. Am. Acad. Dermatol. | pmid:3013957 |
Stymne S and Stobart AK | Biosynthesis of gamma-linolenic acid in cotyledons and microsomal preparations of the developing seeds of common borage (Borago officinalis). | 1986 | Biochem. J. | pmid:3028375 |
Jamal GA et al. | Gamma-linolenic acid in diabetic neuropathy. | 1986 | Lancet | pmid:2871365 |
Wolkin A et al. | Essential fatty acid supplementation in tardive dyskinesia. | 1986 | Am J Psychiatry | pmid:3013033 |
Bégin ME and Das UN | A deficiency in dietary gamma-linolenic and/or eicosapentaenoic acids may determine individual susceptibility to AIDS. | 1986 | Med. Hypotheses | pmid:3014282 |
Costall B et al. | Dihomo-gamma-linolenic acid, prostaglandins and dyskinesias. | 1986 | Prog. Lipid Res. | pmid:2827191 |
Dib A and Carreau JP | Effects of gamma-linolenic acid supplementation on lipogenesis regulation in pregnant zinc-deficient rat and fetus. | 1986 | Int. J. Biochem. | pmid:3026865 |
Viikari J and Lehtonen A | Effect of primrose oil on serum lipids and blood pressure in hyperlipidemic subjects. | 1986 | Int J Clin Pharmacol Ther Toxicol | pmid:3028968 |
Bursztyn PG and King MH | Fat induced hypertension in rabbits: the effects of dietary linoleic and linolenic acid. | 1986 | J. Hypertens. | pmid:3029216 |
Sugano M et al. | Hypocholesterolemic effect of gamma-linolenic acid as evening primrose oil in rats. | 1986 | Ann. Nutr. Metab. | pmid:3752928 |
Godfrey DG et al. | Effects of dietary supplementation on autoimmunity in the MRL/lpr mouse: a preliminary investigation. | 1986 | Ann. Rheum. Dis. | pmid:3492970 |
Morrison CS | Leg ulceration and Efamol. | 1986 | N. Z. Med. J. | pmid:3463912 |
Simpson LO | Leg ulceration and Efamol. | 1986 | N. Z. Med. J. | pmid:3466083 |
Morrison CS | Leg ulcers and Efamol. | 1986 | N. Z. Med. J. | pmid:3468432 |
Singer P et al. | Serum triglycerides and HDL cholesterol from SHR after evening primrose oil and other polyunsaturated fats. | 1986 | Prostaglandins Leukot Med | pmid:3523538 |
Ferrando J | [Clinical trial of a topical preparation containing urea, sunflower oil, evening primrose oil, wheat germ oil and sodium pyruvate, in several hyperkeratotic skin conditions]. | 1986 | Med Cutan Ibero Lat Am | pmid:3528709 |
Oxholm P et al. | Patients with primary Sjögren's syndrome treated for two months with evening primrose oil. | 1986 | Scand. J. Rheumatol. | pmid:3529370 |
Manthorpe R and Prause JU | Treatment of Sjögren's syndrome: an overview. | 1986 | Scand. J. Rheumatol. Suppl. | pmid:3296150 |
Horrobin DF | Essential fatty acid and prostaglandin metabolism in Sjögren's syndrome, systemic sclerosis and rheumatoid arthritis. | 1986 | Scand. J. Rheumatol. Suppl. | pmid:3296151 |
Fujiwara F et al. | Antitumor effect of gamma-linolenic acid on cultured human neuroblastoma cells. | 1986 | Prostaglandins Leukot Med | pmid:3020590 |
Strong AM et al. | The effect of oral linoleic acid and gamma-linolenic acid (Efamol [G]). | 1985 Nov-Dec | Br J Clin Pract | pmid:4092010 |