Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Vaddadi KS | Use of gamma-linolenic acid in the treatment of schizophrenia and tardive dyskinesia. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1321448 |
Horrobin DF | The relationship between schizophrenia and essential fatty acid and eicosanoid metabolism. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1321449 |
Vang K and Ziboh VA | 15-lipoxygenase metabolites of gamma-linolenic acid/eicosapentaenoic acid suppress growth and arachidonic acid metabolism in human prostatic adenocarcinoma cells: possible implications of dietary fatty acids. | 2005 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:15850718 |
Jiang WG et al. | Peroxisome proliferator activated receptor-gamma (PPAR-gamma) mediates the action of gamma linolenic acid in breast cancer cells. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780877 |
Fokkema MR et al. | Short-term supplementation of low-dose gamma-linolenic acid (GLA), alpha-linolenic acid (ALA), or GLA plus ALA does not augment LCP omega 3 status of Dutch vegans to an appreciable extent. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090255 |
Dines KC et al. | Effectiveness of natural oils as sources of gamma-linolenic acid to correct peripheral nerve conduction velocity abnormalities in diabetic rats: modulation by thromboxane A2 inhibition. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8931113 |
Miles EA et al. | Self-reported health problems in young male subjects supplementing their diet with oils rich in eicosapentaenoic, gamma-linolenic and stearidonic acids. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16820286 |
Arisaka M et al. | Fatty acid and prostaglandin metabolism in children with diabetes mellitus. II. The effect of evening primrose oil supplementation on serum fatty acid and plasma prostaglandin levels. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1871184 |
Hrelia S et al. | Kinetic analysis of delta-6-desaturation in liver microsomes: influence of gamma-linoleic acid dietary supplementation to young and old rats. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1808628 |
Engler MM and Engler MB | Dietary borage oil alters plasma, hepatic and vascular tissue fatty acid composition in spontaneously hypertensive rats. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9758202 |
van Rooyen J et al. | Diet can manipulate the metabolism of EPA and GLA in erythrocyte membrane and plasma. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9758205 |
Gardiner NS and Duncan JR | Possible involvement of delta-6-desaturase in control of melanoma growth by gamma-linolenic acid. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1650000 |
Dirks J et al. | Cytokine levels affected by gamma-linolenic acid. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9849654 |
Seegers JC et al. | Comparative anti-mitotic effects of lithium gamma-linolenate, gamma-linolenic acid and arachidonic acid, on transformed and embryonic cells. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9849656 |
Morphake P et al. | Alteration of cyclosporine (CsA)-induced nephrotoxicity by gamma linolenic acid (GLA) and eicosapentaenoic acid (EPA) in Wistar rats. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8146206 |
Engler MM | Comparative study of diets enriched with evening primrose, black currant, borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8259378 |
Kahler CP and Du Plooy WJ | Effect of gammalinolenic acid, dihomogammalinolenic acid, ascorbyl-6-gammalinolenic acid, and ascorbyl-6-dihomo gammalinolenic acid on histamine- and methacholine-induced contraction of the isolated guinea pig tracheal chain. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9654407 |
Moodley J and Norman RJ | Attempts at dietary alteration of prostaglandin pathways in the management of pre-eclampsia. | 1989 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2608693 |
Bunce OR and Abou-El-Ela SH | Eicosanoid synthesis and ornithine decarboxylase activity in mammary tumors of rats fed varying levels and types of N-3 and/or N-6 fatty acids. | 1990 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:2177199 |
Rosenstein ED et al. | Pilot study of dietary fatty acid supplementation in the treatment of adult periodontitis. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12591005 |