Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dyer O | Doctor accused of giving false information to drug trial. | 2002 | BMJ | pmid:12269314 |
Tso P et al. | Intestinal absorption and lymphatic transport of a high gamma-linolenic acid canola oil in lymph fistula Sprague-Dawley rats. | 2002 | J. Nutr. | pmid:11823581 |
Deng X et al. | Regulation of the rat SREBP-1c promoter in primary rat hepatocytes. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11779162 |
Senanayake SP and Shahidi F | Structured lipids via lipase-catalyzed incorporation of eicosapentaenoic acid into borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils. | 2002 | J. Agric. Food Chem. | pmid:11804516 |
Jack AM et al. | Effects of diabetes and evening primrose oil treatment on responses of aorta, corpus cavernosum and mesenteric vasculature in rats. | 2002 | Life Sci. | pmid:12175702 |
Harris NM et al. | Intravesical meglumine gamma-linolenic acid in superficial bladder cancer: an efficacy study. | 2002 | Eur. Urol. | pmid:12121728 |
Hornych A et al. | The effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandin synthesis in older subjects. | 2002 | Bratisl Lek Listy | pmid:12190041 |
Theander E et al. | Gammalinolenic acid treatment of fatigue associated with primary Sjögren's syndrome. | 2002 | Scand. J. Rheumatol. | pmid:12109650 |
Furse RK et al. | Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes. | 2002 | J. Clin. Immunol. | pmid:11998897 |
Gema H et al. | Production of gamma-linolenic acid by Cunninghamella echinulata cultivated on glucose and orange peel. | 2002 | Appl. Microbiol. Biotechnol. | pmid:11935180 |
Hong H et al. | High-level production of gamma-linolenic acid in Brassica juncea using a delta6 desaturase from Pythium irregulare. | 2002 | Plant Physiol. | pmid:12011365 |
Patel GK and Logan RA | Golden nail pigmentation. | 2002 | J Dermatolog Treat | pmid:12006139 |
Leigh-Firbank EC et al. | Eicosapentaenoic acid and docosahexaenoic acid from fish oils: differential associations with lipid responses. | 2002 | Br. J. Nutr. | pmid:12010583 |
Braddock R et al. | gamma-Linoleic acid and ascorbic acid ameliorate the effects of experimental diabetes on electrolyte and bone homeostasis in pregnant rats. | 2002 | J. Endocrinol. | pmid:12010635 |
Crook TJ et al. | The effects of meglumine gamma linolenic acid (MeGLA) on an organ culture model of superficial bladder cancer. | 2002 | Urol. Res. | pmid:11942327 |
GarcÃa-Maroto F et al. | Cloning and molecular characterization of the delta6-desaturase from two echium plant species: production of GLA by heterologous expression in yeast and tobacco. | 2002 | Lipids | pmid:12030323 |
Khunyoshyeng S et al. | Differential expression of desaturases and changes in fatty acid composition during sporangiospore germination and development in Mucor rouxii. | 2002 | Fungal Genet. Biol. | pmid:12223185 |
Whelan J et al. | Dietary EPA reduces tumor load in ApcMin/+ mice by altering arachidonic acid metabolism, but conjugated linoleic acid, gamma--and alpha-linolenic acids have no effect. | 2002 | Adv. Exp. Med. Biol. | pmid:12664643 |
Pham H and Ziboh VA | 5 alpha-reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids. | 2002 | J. Steroid Biochem. Mol. Biol. | pmid:12589947 |
Das UN | Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. | 2002 | Nutrition | pmid:12297217 |
Yoon S et al. | The therapeutic effect of evening primrose oil in atopic dermatitis patients with dry scaly skin lesions is associated with the normalization of serum gamma-interferon levels. | 2002 Jan-Feb | Skin Pharmacol. Appl. Skin Physiol. | pmid:11803254 |
Das UN | Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. | 2002 Jul-Aug | Nutrition | pmid:12093450 |
Funtikova NS et al. | [Synthesis of biologically active lipids by fungus Mucor lusitanicus 306D grown on media with various composition]. | 2002 Nov-Dec | Prikl. Biokhim. Mikrobiol. | pmid:12449793 |
Harris NM et al. | Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma. | 2003 | Cancer | pmid:12491507 |
Pham H et al. | Activation of peroxisome proliferator-activated receptor (PPAR)-gamma by 15S-hydroxyeicosatrienoic acid parallels growth suppression of androgen-dependent prostatic adenocarcinoma cells. | 2003 | Cancer Lett. | pmid:12445673 |
Shotton HR et al. | The effectiveness of treatments of diabetic autonomic neuropathy is not the same in autonomic nerves supplying different organs. | 2003 | Diabetes | pmid:12502507 |
Delmonte P et al. | Synthesis and isolation of trans-7,cis-9 octadecadienoic acid and other CLA isomers by base conjugation of partially hydrogenated gamma-linolenic acid. | 2003 | Lipids | pmid:12880116 |
Surette ME et al. | Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects. | 2003 | Clin Ther | pmid:12852710 |
Surette ME et al. | Inhibition of leukotriene biosynthesis by a novel dietary fatty acid formulation in patients with atopic asthma: a randomized, placebo-controlled, parallel-group, prospective trial. | 2003 | Clin Ther | pmid:12852711 |
Whitehouse PA et al. | Synergistic activity of gamma-linolenic acid and cytotoxic drugs against pancreatic adenocarcinoma cell lines. | 2003 | Pancreatology | pmid:14526145 |
Song C et al. | Effects of dietary n-3 or n-6 fatty acids on interleukin-1beta-induced anxiety, stress, and inflammatory responses in rats. | 2003 | J. Lipid Res. | pmid:12837849 |
Gimeno RE et al. | Characterization of a heart-specific fatty acid transport protein. | 2003 | J. Biol. Chem. | pmid:12556534 |
Vogelzang JL | Fat facts and fallacies. | 2003 | Home Healthc Nurse | pmid:14614382 |
Koletzko B et al. | Fatty acid profiles, antioxidant status, and growth of preterm infants fed diets without or with long-chain polyunsaturated fatty acids. A randomized clinical trial. | 2003 | Eur J Nutr | pmid:14569405 |
Arimura T et al. | Caspase-independent apoptosis induced by evening primrose extract in Ehrlich ascites tumor cells. | 2003 | Cancer Lett. | pmid:14580681 |
Barabino S et al. | Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. | 2003 | Cornea | pmid:12605039 |
Djoussé L et al. | Dietary linolenic acid is inversely associated with plasma triacylglycerol: the National Heart, Lung, and Blood Institute Family Heart Study. | 2003 | Am. J. Clin. Nutr. | pmid:14668270 |
Williams HC | Evening primrose oil for atopic dermatitis. | 2003 | BMJ | pmid:14670851 |
Takwale A et al. | Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. | 2003 | BMJ | pmid:14670885 |
Macrì A et al. | Effect of linoleic acid and gamma-linolenic acid on tear production, tear clearance and on the ocular surface after photorefractive keratectomy. | 2003 | Graefes Arch. Clin. Exp. Ophthalmol. | pmid:12768289 |
Jelińska M et al. | Effects of dietary linseed, evening primrose or fish oils on fatty acid and prostaglandin E2 contents in the rat livers and 7,12-dimethylbenz[a]anthracene-induced tumours. | 2003 | Biochim. Biophys. Acta | pmid:12697300 |
van Gool CJ et al. | Gamma-linolenic acid supplementation for prophylaxis of atopic dermatitis--a randomized controlled trial in infants at high familial risk. | 2003 | Am. J. Clin. Nutr. | pmid:12663296 |
Spector SL and Surette ME | Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma? | 2003 | Ann. Allergy Asthma Immunol. | pmid:12722956 |
Vecera R et al. | Antioxidant status, lipoprotein profile and liver lipids in rats fed on high-cholesterol diet containing currant oil rich in n-3 and n-6 polyunsaturated fatty acids. | 2003 | Physiol Res | pmid:12678660 |
Seibel MM | Treating hot flushes without hormone replacement therapy. | 2003 | J Fam Pract | pmid:12681090 |
Wainwright PE et al. | Effects of high-gamma-linolenic acid canola oil compared with borage oil on reproduction, growth, and brain and behavioral development in mice. | 2003 | Lipids | pmid:12733750 |
Soeken KL et al. | Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. | 2003 | Rheumatology (Oxford) | pmid:12709541 |
Duttaroy AK et al. | Acyl-CoA thioesterase activity in human placental choriocarcinoma (BeWo), cells: effects of fatty acids. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12538089 |
Pacht ER et al. | Enteral nutrition with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome. | 2003 | Crit. Care Med. | pmid:12576957 |
Xian M et al. | Production of gamma-linolenic acid by disrupted mycelia of Mortierella isabellina. | 2003 | Lett. Appl. Microbiol. | pmid:12581380 |