Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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de La Puerta Vázquez R et al. | Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils. | 2004 | Metab. Clin. Exp. | pmid:14681843 |
Takwale A et al. | Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. | 2003 | BMJ | pmid:14670885 |
Williams HC | Evening primrose oil for atopic dermatitis. | 2003 | BMJ | pmid:14670851 |
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Whitehouse PA et al. | Synergistic activity of gamma-linolenic acid and cytotoxic drugs against pancreatic adenocarcinoma cell lines. | 2003 | Pancreatology | pmid:14526145 |
Huang YS et al. | Effects of repeated gestation and lactation on milk n-6 fatty acid composition in rats fed on a diet rich in 18:2n-6 or 18:3n-6. | 1992 | Br. J. Nutr. | pmid:1445816 |
SHAW R | THE OCCURRENCE OF GAMMA-LINOLENIC ACID IN FUNGI. | 1965 | Biochim. Biophys. Acta | pmid:14320219 |
Cyclical breast pain--what works and what doesn't. | 1992 | Drug Ther Bull | pmid:1425218 | |
MEAD JF and HOWTON DR | Metabolism of essential fatty acids. VII. Conversion of gamma-linolenic acid to arachidonic acid. | 1957 | J. Biol. Chem. | pmid:13502321 |
Furuse M et al. | Effect of gamma-linolenic acid on lipid metabolism in laying hens. | 1992 | Comp Biochem Physiol A Comp Physiol | pmid:1347726 |
Cantrill RC et al. | The effect of n-6 fatty acids on normal and v-Ki ras transformed NIH-3T3 cells. | 1992 Nov-Dec | Anticancer Res. | pmid:1338278 |
Girault C et al. | Effect of dietary gamma-linolenic acid on specific activities of delta 6 desaturation in obese Zucker rats. | 1992 | C. R. Seances Soc. Biol. Fil. | pmid:1337306 |
Mengeaud V et al. | Effects of eicosapentaenoic acid, gamma-linolenic acid and prostaglandin E1 on three human colon carcinoma cell lines. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1337209 |
Raederstorff D and Moser U | Borage or primrose oil added to standardized diets are equivalent sources for gamma-linolenic acid in rats. | 1992 | Lipids | pmid:1336802 |
Ergan F et al. | Lipase specificity against some fatty acids? | 1992 | Ann. N. Y. Acad. Sci. | pmid:1335712 |
Engler MM et al. | Dietary gamma-linolenic acid lowers blood pressure and alters aortic reactivity and cholesterol metabolism in hypertension. | 1992 | J. Hypertens. | pmid:1335001 |
Horrobin DF | Nutritional and medical importance of gamma-linolenic acid. | 1992 | Prog. Lipid Res. | pmid:1334266 |
Gunstone FD | Gamma linolenic acid--occurrence and physical and chemical properties. | 1992 | Prog. Lipid Res. | pmid:1334265 |
Hamberg M | Metabolism of 6,9,12-octadecatrienoic acid in the red alga Lithothamnion corallioides: mechanism of formation of a conjugated tetraene fatty acid. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1332713 |
Duffy O et al. | Attenuation of the effects of chronic ethanol administration in the brain lipid content of the developing rat by an oil enriched in gamma linolenic acid. | 1992 | Drug Alcohol Depend | pmid:1330473 |
Fragoso YD and Skinner ER | The effect of gammalinolenic acid on the subfractions of plasma high density lipoprotein of the rabbit. | 1992 | Biochem. Pharmacol. | pmid:1329758 |
Barre DE and Holub BJ | The effect of borage oil consumption on the composition of individual phospholipids in human platelets. | 1992 | Lipids | pmid:1328794 |
Ormerod LD et al. | Eicosanoid modulation and epithelial wound healing kinetics of the alkali-burned cornea. | 1992 | J Ocul Pharmacol | pmid:1328428 |
Söreide E et al. | Long-term use of gamma-linolenic acid-enriched fat emulsion (PFE 4501): case report. | 1992 May-Jun | Nutrition | pmid:1326350 |
Navarette R et al. | Dietary intake of concentrated gamma-linolenic acid (GLA)-enriched oil suppresses cutaneous level of dihomo-gamma-linolenic acid (DGLA): possible in vivo inhibition of microsomal elongation of GLA to DGLA. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1323857 |
Fan YY and Chapkin RS | Mouse peritoneal macrophage prostaglandin E1 synthesis is altered by dietary gamma-linolenic acid. | 1992 | J. Nutr. | pmid:1322453 |
Ross MA et al. | Heparin reduces Fe(II)-catalyzed peroxidation of linolenic acid. | 1992 | Biochem. Soc. Trans. | pmid:1321761 |
Horrobin DF | The use of gamma-linolenic acid in diabetic neuropathy. | 1992 | Agents Actions Suppl. | pmid:1321553 |
Horrobin DF | The relationship between schizophrenia and essential fatty acid and eicosanoid metabolism. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1321449 |
Vaddadi KS | Use of gamma-linolenic acid in the treatment of schizophrenia and tardive dyskinesia. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1321448 |
Gibson RA et al. | Gamma linolenic acid (GLA) content of encapsulated evening primrose oil products. | 1992 | Lipids | pmid:1318991 |
Kerscher MJ and Korting HC | Treatment of atopic eczema with evening primrose oil: rationale and clinical results. | 1992 | Clin Investig | pmid:1318129 |
Duffy O et al. | Effects of an oil enriched in gamma linolenic acid on locomotor activity and behaviour in the Morris Maze, following in utero ethanol exposure in rats. | 1992 | Drug Alcohol Depend | pmid:1317288 |
Takeda S et al. | Lipid peroxidation in human breast cancer cells in response to gamma-linolenic acid and iron. | 1992 Mar-Apr | Anticancer Res. | pmid:1316091 |
Bégin ME and Ells G | Levels of thiobarbituric acid reactive substances and the cytocidal potential of gammalinolenic and docosahexaenoic acids on ZR-75-1 and CV-1 cells. | 1992 | Lipids | pmid:1315901 |
de Kock M et al. | Effects of gamma-linolenic acid on mitosis and nuclear morphology in osteogenic sarcoma cells. | 1992 | S. Afr. Med. J. | pmid:1315459 |
Van Biervliet JP et al. | Serum cholesterol, cholesteryl ester, and high-density lipoprotein development in newborn infants: response to formulas supplemented with cholesterol and gamma-linolenic acid. | 1992 | J. Pediatr. | pmid:1313864 |
Lockett MJ and Tomlinson DR | The effects of dietary treatment with essential fatty acids on sciatic nerve conduction and activity of the Na+/K+ pump in streptozotocin-diabetic rats. | 1992 | Br. J. Pharmacol. | pmid:1313726 |
St Louis C et al. | Antihypertensive effect of gamma-linolenic acid in spontaneously hypertensive rats. | 1992 | Hypertension | pmid:1310479 |
Mimouni V et al. | Evidence for insulin dependent hepatic microsomal gamma-linolenic acid chain elongation in spontaneously diabetic Wistar BB rats. | 1992 | Biochim. Biophys. Acta | pmid:1310052 |
Ziboh VA and Fletcher MP | Dose-response effects of dietary gamma-linolenic acid-enriched oils on human polymorphonuclear-neutrophil biosynthesis of leukotriene B4. | 1992 | Am. J. Clin. Nutr. | pmid:1309474 |
Hayashi Y et al. | Anticancer effects of free polyunsaturated fatty acids in an oily lymphographic agent following intrahepatic arterial administration to a rabbit bearing VX-2 tumor. | 1992 | Cancer Res. | pmid:1309442 |