Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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O'Brien PM et al. | The effect of dietary supplementation with linoleic and gammalinolenic acids on the pressor response to angiotensin II--a possible role in pregnancy-induced hypertension? | 1985 | Br J Clin Pharmacol | pmid:2985102 |
Das UN et al. | Prostaglandins and their precursors can modify genetic damage-induced by gamma-radiation and benzo(a)pyrene. | 1985 | Prostaglandins | pmid:2994175 |
Pascaud M and Strouve-Vallet C | Desaturation of 14C linoleic acid by the rat fetus. | 1985 | Ann. Nutr. Metab. | pmid:2983600 |
Bégin ME et al. | Selective killing of human cancer cells by polyunsaturated fatty acids. | 1985 | Prostaglandins Leukot Med | pmid:2864701 |
Huang YS et al. | Effect of dietary alpha- and gamma-linolenic acid on tissue fatty acids in guinea pigs. | 1985 | Proc. Soc. Exp. Biol. Med. | pmid:2857052 |
Pye JK et al. | Clinical experience of drug treatments for mastalgia. | 1985 | Lancet | pmid:2862523 |
Segarnick DJ et al. | Gamma-linolenic acid inhibits the development of the ethanol-induced fatty liver. | 1985 | Prostaglandins Leukot Med | pmid:2986177 |
Botha JH et al. | The response of human carcinoma cell lines to gamma-linolenic acid with special reference to the effects of agents which influence prostaglandin and thromboxane synthesis. | 1985 | Prostaglandins Leukot Med | pmid:2994114 |
Segarnick DJ et al. | Prostanoid modulation (mediation?) of certain behavioral effects of ethanol. | 1985 | Pharmacol. Biochem. Behav. | pmid:2994122 |
de Bravo MM et al. | Metabolism of gammalinolenic acid by human blood platelet microsomes. | 1985 | Biochem. Int. | pmid:2994669 |
Mills DE et al. | Gamma linolenic acid attenuates cardiovascular responses to stress in borderline hypertensive rats. | 1985 | Lipids | pmid:2995750 |
Booyens J et al. | The use of drugs for the inhibition of prostaglandin or leukotriene synthesis from arachidonic acid is theoretically hazardous. | 1985 | Med. Hypotheses | pmid:2995775 |
Puolakka J et al. | Biochemical and clinical effects of treating the premenstrual syndrome with prostaglandin synthesis precursors. | 1985 | J Reprod Med | pmid:3839018 |
Robinson KM and Botha JH | Effects of gamma-linolenic acid, dihomo-gamma-linolenic acid and ethanol on cultured human mammary carcinoma cells. | 1985 | Prostaglandins Leukot Med | pmid:2999828 |
Bamford JT et al. | Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids). | 1985 | J. Am. Acad. Dermatol. | pmid:3908514 |
Kumar S et al. | Prediction of response to endocrine therapy in pronounced cyclical mastalgia using dynamic tests of prolactin release. | 1985 | Clin. Endocrinol. (Oxf) | pmid:3938354 |
Wright S | Atopic dermatitis and essential fatty acids: a biochemical basis for atopy? | 1985 | Acta Derm Venereol Suppl (Stockh) | pmid:3890448 |
Soma M et al. | The effects of hydrogenated coconut oil, safflower oil, and evening primrose oil on development of hypertension and sodium handling in spontaneously hypertensive rats. | 1985 | Can. J. Physiol. Pharmacol. | pmid:4005704 |
Webb J and McCredie M | Primary Sjögren's syndrome treated with Efamol/efavit. A double-blind cross-over investigation. | 1985 | Rheumatol. Int. | pmid:4048763 |
Belch JJ et al. | Evening primrose oil (Efamol) in the treatment of Raynaud's phenomenon: a double blind study. | 1985 | Thromb. Haemost. | pmid:4082084 |
Wainwright P et al. | gamma-Linolenic acid fails to prevent the effects of prenatal ethanol exposure on brain and behavioral development in B6D2F2 mice. | 1985 Jul-Aug | Alcohol. Clin. Exp. Res. | pmid:2996378 |
Strong AM et al. | The effect of oral linoleic acid and gamma-linolenic acid (Efamol [G]). | 1985 Nov-Dec | Br J Clin Pract | pmid:4092010 |
Skogh M | Atopic eczema unresponsive to evening primrose oil (linoleic and gamma-linolenic acids) | 1986 | J. Am. Acad. Dermatol. | pmid:3013957 |
Stymne S and Stobart AK | Biosynthesis of gamma-linolenic acid in cotyledons and microsomal preparations of the developing seeds of common borage (Borago officinalis). | 1986 | Biochem. J. | pmid:3028375 |
Jamal GA et al. | Gamma-linolenic acid in diabetic neuropathy. | 1986 | Lancet | pmid:2871365 |
Wolkin A et al. | Essential fatty acid supplementation in tardive dyskinesia. | 1986 | Am J Psychiatry | pmid:3013033 |
Bégin ME and Das UN | A deficiency in dietary gamma-linolenic and/or eicosapentaenoic acids may determine individual susceptibility to AIDS. | 1986 | Med. Hypotheses | pmid:3014282 |
Costall B et al. | Dihomo-gamma-linolenic acid, prostaglandins and dyskinesias. | 1986 | Prog. Lipid Res. | pmid:2827191 |
Dib A and Carreau JP | Effects of gamma-linolenic acid supplementation on lipogenesis regulation in pregnant zinc-deficient rat and fetus. | 1986 | Int. J. Biochem. | pmid:3026865 |
Viikari J and Lehtonen A | Effect of primrose oil on serum lipids and blood pressure in hyperlipidemic subjects. | 1986 | Int J Clin Pharmacol Ther Toxicol | pmid:3028968 |
Bursztyn PG and King MH | Fat induced hypertension in rabbits: the effects of dietary linoleic and linolenic acid. | 1986 | J. Hypertens. | pmid:3029216 |
Sugano M et al. | Hypocholesterolemic effect of gamma-linolenic acid as evening primrose oil in rats. | 1986 | Ann. Nutr. Metab. | pmid:3752928 |
Godfrey DG et al. | Effects of dietary supplementation on autoimmunity in the MRL/lpr mouse: a preliminary investigation. | 1986 | Ann. Rheum. Dis. | pmid:3492970 |
Morrison CS | Leg ulceration and Efamol. | 1986 | N. Z. Med. J. | pmid:3463912 |
Simpson LO | Leg ulceration and Efamol. | 1986 | N. Z. Med. J. | pmid:3466083 |
Morrison CS | Leg ulcers and Efamol. | 1986 | N. Z. Med. J. | pmid:3468432 |
Singer P et al. | Serum triglycerides and HDL cholesterol from SHR after evening primrose oil and other polyunsaturated fats. | 1986 | Prostaglandins Leukot Med | pmid:3523538 |
Ferrando J | [Clinical trial of a topical preparation containing urea, sunflower oil, evening primrose oil, wheat germ oil and sodium pyruvate, in several hyperkeratotic skin conditions]. | 1986 | Med Cutan Ibero Lat Am | pmid:3528709 |
Oxholm P et al. | Patients with primary Sjögren's syndrome treated for two months with evening primrose oil. | 1986 | Scand. J. Rheumatol. | pmid:3529370 |
Manthorpe R and Prause JU | Treatment of Sjögren's syndrome: an overview. | 1986 | Scand. J. Rheumatol. Suppl. | pmid:3296150 |
Horrobin DF | Essential fatty acid and prostaglandin metabolism in Sjögren's syndrome, systemic sclerosis and rheumatoid arthritis. | 1986 | Scand. J. Rheumatol. Suppl. | pmid:3296151 |
Fujiwara F et al. | Antitumor effect of gamma-linolenic acid on cultured human neuroblastoma cells. | 1986 | Prostaglandins Leukot Med | pmid:3020590 |
Huang YS et al. | Protective effect of gamma-linolenic acid on aspirin-induced gastric hemorrhage in rats. | 1987 | Digestion | pmid:3030865 |
Fujiwara F et al. | Fatty acid modification of cultured neuroblastoma cells by gamma linolenic acid relevant to its antitumor effect. | 1987 | Prostaglandins Leukot Med | pmid:2829239 |
Van der Merwe CF et al. | Oral gamma-linolenic acid in 21 patients with untreatable malignancy. An ongoing pilot open clinical trial. | 1987 | Br J Clin Pract | pmid:2837264 |
Papanikolaou N | Alteration of mercuric chloride-induced autoimmune glomerulonephritis in brown-Norway rats by herring oil, evening primrose oil and OKY-046 a selective TXA-synthetase inhibitor. | 1987 | Prostaglandins Leukot Med | pmid:3475724 |
Papanikolaou N et al. | Effect of thromboxane A2-synthetase inhibitor OKY-046 and evening primrose oil (Efamol) on mercuric chloride induced autoimmune glomerulonephritis in Brown-Norway rats. | 1987 | Prog. Clin. Biol. Res. | pmid:3671393 |
Guenther L and Wexler D | Efamol in the treatment of atopic dermatitis. | 1987 | J. Am. Acad. Dermatol. | pmid:3680673 |
Glen I et al. | The role of essential fatty acids in alcohol dependence and tissue damage. | 1987 | Alcohol. Clin. Exp. Res. | pmid:3551662 |
Bordoni A et al. | [Treatment of premenstrual syndrome with essential fatty acids (evening primrose oil)]. | 1987 | G Clin Med | pmid:3609594 |