Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dasgupta S and Bhattacharyya DK | Dietary effect of gamma-linolenic acid on the lipid profile of rat fed erucic acid rich oil. | 2007 | J Oleo Sci | pmid:17938547 |
Sýkora J et al. | High-performance liquid chromatography with nuclear magnetic resonance detection--A method for quantification of alpha- and gamma-linolenic acids in their mixtures with free fatty acids. | 2007 | J Chromatogr A | pmid:17157864 |
Martin TA et al. | Enhanced tight junction function in human breast cancer cells by antioxidant, selenium and polyunsaturated lipid. | 2007 | J. Cell. Biochem. | pmid:17243118 |
Matta JA et al. | TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. | 2007 | J. Physiol. (Lond.) | pmid:17038422 |
Pitel S et al. | At low doses, a gamma-linolenic acid-lipoic acid conjugate is more effective than docosahexaenoic acid-enriched phospholipids in preventing neuropathy in diabetic rats. | 2007 | J. Nutr. | pmid:17237313 |
Christie A et al. | Effectiveness of nonpharmacological and nonsurgical interventions for patients with rheumatoid arthritis: an overview of systematic reviews. | 2007 | Phys Ther | pmid:17906290 |
Dobryniewski J et al. | [The gamma-linolenic acid (GLA)--the therapeutic value]. | 2007 | Prz. Lek. | pmid:17892041 |
Theilla M et al. | A diet enriched in eicosapentanoic acid, gamma-linolenic acid and antioxidants in the prevention of new pressure ulcer formation in critically ill patients with acute lung injury: A randomized, prospective, controlled study. | 2007 | Clin Nutr | pmid:17933438 |
Garaiova I et al. | A randomised cross-over trial in healthy adults indicating improved absorption of omega-3 fatty acids by pre-emulsification. | 2007 | Nutr J | pmid:17254329 |
Das UN | Gamma-linolenic acid therapy of human glioma-a review of in vitro, in vivo, and clinical studies. | 2007 | Med. Sci. Monit. | pmid:17599036 |
Villamor E et al. | Long-chain n-6 polyunsaturated fatty acids in breast milk decrease the risk of HIV transmission through breastfeeding. | 2007 | Am. J. Clin. Nutr. | pmid:17823433 |
Lindmark L and Clough P | A 5-month open study with long-chain polyunsaturated fatty acids in dyslexia. | 2007 | J Med Food | pmid:18158838 |
Guo SX et al. | [Influence of methyl esterification on the ultraviolet absorption of gamma-linolenic acid]. | 2007 | Zhong Yao Cai | pmid:18236761 |
Puri BK | The safety of evening primrose oil in epilepsy. | 2007 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:17764919 |
Lu H et al. | [Cloning and expression of a delta6-fatty acid desaturase gene from Rhizopus stolonifer in Saccharomyces cervisiae]. | 2007 | Wei Sheng Wu Xue Bao | pmid:17436625 |
Cho HS et al. | Anti-wrinkling effects of the mixture of vitamin C, vitamin E, pycnogenol and evening primrose oil, and molecular mechanisms on hairless mouse skin caused by chronic ultraviolet B irradiation. | 2007 | Photodermatol Photoimmunol Photomed | pmid:17803593 |
Guil-Guerrero JL et al. | Gamma-linolenic acid from Cape Verdian Boraginaceae. | 2006 | Nat. Prod. Res. | pmid:16286301 |
Umeda-Sawada R et al. | Distribution and metabolism of dihomo-gamma-linolenic acid (DGLA, 20:3n-6) by oral supplementation in rats. | 2006 | Biosci. Biotechnol. Biochem. | pmid:16960355 |
Kim J et al. | Comparative effect of gromwell (Lithospermum erythrorhizon) extract and borage oil on reversing epidermal hyperproliferation in guinea pigs. | 2006 | Biosci. Biotechnol. Biochem. | pmid:16960390 |
Hatanaka E et al. | Systematic study on ROS production induced by oleic, linoleic, and gamma-linolenic acids in human and rat neutrophils. | 2006 | Free Radic. Biol. Med. | pmid:16962937 |
Pontes-Arruda A et al. | Effects of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in mechanically ventilated patients with severe sepsis and septic shock. | 2006 | Crit. Care Med. | pmid:16850002 |
Fakas S et al. | Lipids of Cunninghamella echinulata with emphasis to gamma-linolenic acid distribution among lipid classes. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16850299 |
Kong X et al. | Induction of apoptosis in K562/ADM cells by gamma-linolenic acid involves lipid peroxidation and activation of caspase-3. | 2006 | Chem. Biol. Interact. | pmid:16857180 |
Pham H et al. | Dietary gamma-linolenate attenuates tumor growth in a rodent model of prostatic adenocarcinoma via suppression of elevated generation of PGE(2) and 5S-HETE. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16567086 |
Singer P et al. | Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury. | 2006 | Crit. Care Med. | pmid:16484911 |
Das UN and Rao KP | Effect of gamma-linolenic acid and prostaglandins E1 on gamma-radiation and chemical-induced genetic damage to the bone marrow cells of mice. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16488586 |
Martin TA et al. | Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation. | 2006 | J. Cell. Biochem. | pmid:16514648 |
Pacht ER | Enteral therapy to decrease morbidity and improve survival in acute respiratory distress syndrome: its time has come. | 2006 | Crit. Care Med. | pmid:16921322 |
Arab K et al. | Conjugated linoleic acid, unlike other unsaturated fatty acids, strongly induces glutathione synthesis without any lipoperoxidation. | 2006 | Br. J. Nutr. | pmid:17092368 |
Das UN | Tumoricidal and anti-angiogenic actions of gamma-linolenic acid and its derivatives. | 2006 | Curr Pharm Biotechnol | pmid:17168663 |
Morse NL and Clough PM | A meta-analysis of randomized, placebo-controlled clinical trials of Efamol evening primrose oil in atopic eczema. Where do we go from here in light of more recent discoveries? | 2006 | Curr Pharm Biotechnol | pmid:17168667 |
Kapoor R and Huang YS | Gamma linolenic acid: an antiinflammatory omega-6 fatty acid. | 2006 | Curr Pharm Biotechnol | pmid:17168669 |
DeMichele SJ et al. | A nutritional strategy to improve oxygenation and decrease morbidity in patients who have acute respiratory distress syndrome. | 2006 | Respir Care Clin N Am | pmid:17150431 |
Kim JJ et al. | Properties of cholesterol-reduced butter made with beta-cyclodextrin and added evening primrose oil and phytosterols. | 2006 | J. Dairy Sci. | pmid:17106080 |
Gasperino J and Kvetan V | Acute lung injury and nutritional support. | 2006 | Crit. Care Med. | pmid:16550085 |
Yu Z et al. | Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acid. | 2006 | J. Pharmacol. Exp. Ther. | pmid:16421287 |
Tocher DR et al. | Effect of diets enriched in Delta6 desaturated fatty acids (18:3n-6 and 18:4n-3), on growth, fatty acid composition and highly unsaturated fatty acid synthesis in two populations of Arctic charr (Salvelinus alpinus L.). | 2006 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:16630735 |
Kitz R et al. | Impact of early dietary gamma-linolenic acid supplementation on atopic eczema in infancy. | 2006 | Pediatr Allergy Immunol | pmid:16618360 |
Chen YC et al. | Therapeutic effect of topical gamma-linolenic acid on refractory uremic pruritus. | 2006 | Am. J. Kidney Dis. | pmid:16797388 |
Miles EA et al. | Self-reported health problems in young male subjects supplementing their diet with oils rich in eicosapentaenoic, gamma-linolenic and stearidonic acids. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16820286 |
Hongsthong A et al. | Revealing the complementation of ferredoxin by cytochrome b (5) in the Spirulina- (6)-desaturation reaction by N-terminal fusion and co-expression of the fungal-cytochrome b (5) domain and Spirulina- (6)-acyl-lipid desaturase. | 2006 | Appl. Microbiol. Biotechnol. | pmid:16575563 |
Das UN | Re: Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene. | 2006 | J. Natl. Cancer Inst. | pmid:16705127 |
Azevedo-Martins AK et al. | Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. | 2006 | Toxicol In Vitro | pmid:16644178 |
Verhoeven MO et al. | Effect of a combination of isoflavones and Actaea racemosa Linnaeus on climacteric symptoms in healthy symptomatic perimenopausal women: a 12-week randomized, placebo-controlled, double-blind study. | 2005 Jul-Aug | Menopause | pmid:16037756 |
Goyal A and Mansel RE | A randomized multicenter study of gamolenic acid (Efamast) with and without antioxidant vitamins and minerals in the management of mastalgia. | 2005 Jan-Feb | Breast J | pmid:15647077 |
Liu FX et al. | [Study on the encapsulation technique of high purity gamma-linolenic acid, part 1--Single factor, and two-factor tests for encapsulation process]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:15810447 |
Menendez JA et al. | Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis. | 2005 | Med. Hypotheses | pmid:15607568 |
Vahedi K et al. | A 3-month double-blind randomised study comparing an olive oil- with a soyabean oil-based intravenous lipid emulsion in home parenteral nutrition patients. | 2005 | Br. J. Nutr. | pmid:16351767 |
Aragona P et al. | Systemic omega-6 essential fatty acid treatment and pge1 tear content in Sjögren's syndrome patients. | 2005 | Invest. Ophthalmol. Vis. Sci. | pmid:16303936 |
Patnayak S and Sree A | Screening of bacterial associates of marine sponges for single cell oil and PUFA. | 2005 | Lett. Appl. Microbiol. | pmid:15836739 |