Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Ring J and Kleinheinz A | [Evening primrose oil in neurodermatitis?]. | 1991 | Med Monatsschr Pharm | pmid:1943974 |
Horrobin DF et al. | The effects of evening primrose oil, safflower oil and paraffin on plasma fatty acid levels in humans: choice of an appropriate placebo for clinical studies on primrose oil. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1871175 |
Arisaka M et al. | Fatty acid and prostaglandin metabolism in children with diabetes mellitus. II. The effect of evening primrose oil supplementation on serum fatty acid and plasma prostaglandin levels. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1871184 |
Gateley CA and Mansel RE | Management of the painful and nodular breast. | 1991 | Br. Med. Bull. | pmid:1834299 |
Hrelia S et al. | Kinetic analysis of delta-6-desaturation in liver microsomes: influence of gamma-linoleic acid dietary supplementation to young and old rats. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1808628 |
Tauson AH et al. | Effect of evening primrose oil as food supplement on reproduction in the mink. | 1991 | Acta Vet. Scand. | pmid:1814183 |
Tauson AH and Forsberg M | Effect of evening primrose oil as food supplement on reproduction in the blue fox. | 1991 | Acta Vet. Scand. | pmid:1814184 |
Gardiner NS and Duncan JR | Possible involvement of delta-6-desaturase in control of melanoma growth by gamma-linolenic acid. | 1991 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1650000 |
Chapkin RS and Coble KJ | Utilization of gammalinolenic acid by mouse peritoneal macrophages. | 1991 | Biochim. Biophys. Acta | pmid:1655039 |
Freeman MS et al. | The effects of essential fatty acid supplementation on lithium absorption kinetics in guinea pig jejunum. | 1991 | Biochem. Soc. Trans. | pmid:1665438 |
Melnik B and Plewig G | Atopic dermatitis and disturbances of essential fatty acid and prostaglandin E metabolism. | 1991 | J. Am. Acad. Dermatol. | pmid:1666398 |
Gilani S et al. | Chick embryonic development following exposure to ethanol, gamma-linolenic and linolenic acids. | 1991 | Anat Anz | pmid:1666823 |
KristofÃková L et al. | Selection of Rhizopus strains for L(+)-lactic acid and gamma-linolenic acid production. | 1991 | Folia Microbiol. (Praha) | pmid:1668279 |
Simpson LO | Melanoma and fatty acids. | 1991 | N. Z. Med. J. | pmid:1996191 |
Brzeski M et al. | Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. | 1991 | Br. J. Rheumatol. | pmid:1913008 |
Recently introduced products. | 1991 | Drug Ther Bull | pmid:1935601 | |
Holborow P | Melanoma and polyunsaturated fat. | 1991 | N. Z. Med. J. | pmid:2006066 |
Holborow P | Melanoma and fatty acids. | 1991 | N. Z. Med. J. | pmid:2008253 |
Beck SA et al. | Anticachectic and antitumor effect of eicosapentaenoic acid and its effect on protein turnover. | 1991 | Cancer Res. | pmid:1657378 |
Cameron NE et al. | Essential fatty acid diet supplementation. Effects on peripheral nerve and skeletal muscle function and capillarization in streptozocin-induced diabetic rats. | 1991 | Diabetes | pmid:2022301 |
Izumi T et al. | Purification of two forms of arachidonate 15-lipoxygenase from human leukocytes. | 1991 | Eur. J. Biochem. | pmid:1662607 |
Wright S | Atopic eczema. | 1991 | J R Coll Physicians Lond | pmid:1920221 |
Schäfer L and Kragballe K | Supplementation with evening primrose oil in atopic dermatitis: effect on fatty acids in neutrophils and epidermis. | 1991 | Lipids | pmid:1943500 |
Das UN | Tumoricidal action of cis-unsaturated fatty acids and their relationship to free radicals and lipid peroxidation. | 1991 | Cancer Lett. | pmid:1850658 |
Ulmann L et al. | Incorporation into liver microsomal lipids of linoleic and stearic acids and of their respective products of delta 6 and delta 9 desaturation, gamma-linolenic and oleic acids: effect of age and of blackcurrant seed oil. | 1991 | Biochim. Biophys. Acta | pmid:1657182 |
Julu PO and Mutamba A | Comparison of short-term effects of insulin and essential fatty acids on the slowed nerve conduction of streptozotocin diabetes in rats. | 1991 | J. Neurol. Sci. | pmid:1663993 |
Say B | A panacea for all ills? | 1991 Apr 10-16 | Nurs Times | pmid:2020583 |
Ziboh VA and Fletcher MP | Dose-response effects of dietary gamma-linolenic acid-enriched oils on human polymorphonuclear-neutrophil biosynthesis of leukotriene B4. | 1992 | Am. J. Clin. Nutr. | pmid:1309474 |
Mimouni V et al. | Evidence for insulin dependent hepatic microsomal gamma-linolenic acid chain elongation in spontaneously diabetic Wistar BB rats. | 1992 | Biochim. Biophys. Acta | pmid:1310052 |
St Louis C et al. | Antihypertensive effect of gamma-linolenic acid in spontaneously hypertensive rats. | 1992 | Hypertension | pmid:1310479 |
Lockett MJ and Tomlinson DR | The effects of dietary treatment with essential fatty acids on sciatic nerve conduction and activity of the Na+/K+ pump in streptozotocin-diabetic rats. | 1992 | Br. J. Pharmacol. | pmid:1313726 |
Van Biervliet JP et al. | Serum cholesterol, cholesteryl ester, and high-density lipoprotein development in newborn infants: response to formulas supplemented with cholesterol and gamma-linolenic acid. | 1992 | J. Pediatr. | pmid:1313864 |
de Kock M et al. | Effects of gamma-linolenic acid on mitosis and nuclear morphology in osteogenic sarcoma cells. | 1992 | S. Afr. Med. J. | pmid:1315459 |
Bégin ME and Ells G | Levels of thiobarbituric acid reactive substances and the cytocidal potential of gammalinolenic and docosahexaenoic acids on ZR-75-1 and CV-1 cells. | 1992 | Lipids | pmid:1315901 |
Duffy O et al. | Effects of an oil enriched in gamma linolenic acid on locomotor activity and behaviour in the Morris Maze, following in utero ethanol exposure in rats. | 1992 | Drug Alcohol Depend | pmid:1317288 |
Kerscher MJ and Korting HC | Treatment of atopic eczema with evening primrose oil: rationale and clinical results. | 1992 | Clin Investig | pmid:1318129 |
Gibson RA et al. | Gamma linolenic acid (GLA) content of encapsulated evening primrose oil products. | 1992 | Lipids | pmid:1318991 |
Vaddadi KS | Use of gamma-linolenic acid in the treatment of schizophrenia and tardive dyskinesia. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1321448 |
Horrobin DF | The relationship between schizophrenia and essential fatty acid and eicosanoid metabolism. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1321449 |
Horrobin DF | The use of gamma-linolenic acid in diabetic neuropathy. | 1992 | Agents Actions Suppl. | pmid:1321553 |
Ross MA et al. | Heparin reduces Fe(II)-catalyzed peroxidation of linolenic acid. | 1992 | Biochem. Soc. Trans. | pmid:1321761 |
Fan YY and Chapkin RS | Mouse peritoneal macrophage prostaglandin E1 synthesis is altered by dietary gamma-linolenic acid. | 1992 | J. Nutr. | pmid:1322453 |
Navarette R et al. | Dietary intake of concentrated gamma-linolenic acid (GLA)-enriched oil suppresses cutaneous level of dihomo-gamma-linolenic acid (DGLA): possible in vivo inhibition of microsomal elongation of GLA to DGLA. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1323857 |
Scott DW et al. | Comparison of the clinical efficacy of two commercial fatty acid supplements (EfaVet and DVM Derm Caps), evening primrose oil, and cold water marine fish oil in the management of allergic pruritus in dogs: a double-blinded study. | 1992 | Cornell Vet | pmid:1643883 |
Gateley CA et al. | Drug treatments for mastalgia: 17 years experience in the Cardiff Mastalgia Clinic. | 1992 | J R Soc Med | pmid:1548647 |
Gateley CA et al. | Plasma fatty acid profiles in benign breast disorders. | 1992 | Br J Surg | pmid:1596720 |
Horrobin DF | Nutritional and medical importance of gamma-linolenic acid. | 1992 | Prog. Lipid Res. | pmid:1334266 |
Engler MM et al. | Dietary gamma-linolenic acid lowers blood pressure and alters aortic reactivity and cholesterol metabolism in hypertension. | 1992 | J. Hypertens. | pmid:1335001 |
McFayden IJ et al. | Cyclical breast pain--some observations and the difficulties in treatment. | 1992 | Br J Clin Pract | pmid:1286012 |
Hayashi Y et al. | Anticancer effects of free polyunsaturated fatty acids in an oily lymphographic agent following intrahepatic arterial administration to a rabbit bearing VX-2 tumor. | 1992 | Cancer Res. | pmid:1309442 |