gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Stomach Ulcer D013276 75 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Pain D010146 64 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Gastritis D005756 27 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Melanoma D008545 69 associated lipids
Kidney Calculi D007669 7 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Leukemia P388 D007941 43 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Thrombosis D013927 49 associated lipids
Hyperplasia D006965 34 associated lipids
Arteriosclerosis D001161 86 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Psoriasis D011565 47 associated lipids
Alcoholism D000437 27 associated lipids
Bacteriuria D001437 7 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Seizures D012640 87 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Hypertension D006973 115 associated lipids
Dermatitis D003872 30 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Hyperlipidemias D006949 73 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Premenstrual Syndrome D011293 7 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Raynaud Disease D011928 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Dysmenorrhea D004412 9 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Synovitis D013585 15 associated lipids
Arthritis, Psoriatic D015535 3 associated lipids
Atherosclerosis D050197 85 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Insulin Resistance D007333 99 associated lipids
Fatigue D005221 10 associated lipids
Nausea D009325 7 associated lipids
Critical Illness D016638 13 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Acute Lung Injury D055371 33 associated lipids
Intermittent Claudication D007383 6 associated lipids
Fibrocystic Breast Disease D005348 1 associated lipids
Tietze's Syndrome D013991 1 associated lipids
Pityriasis D010915 3 associated lipids
Xerostomia D014987 6 associated lipids
Fallopian Tube Neoplasms D005185 1 associated lipids
Carcinoma, Mucoepidermoid D018277 3 associated lipids
Scurvy D012614 2 associated lipids
Hand Dermatoses D006229 5 associated lipids
Mucocele D009078 1 associated lipids
Salivary Gland Diseases D012466 1 associated lipids
Gastritis, Atrophic D005757 4 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Carpal Tunnel Syndrome D002349 3 associated lipids
Back Pain D001416 5 associated lipids
Urolithiasis D052878 1 associated lipids
Mastocytoma D034801 3 associated lipids
Ecchymosis D004438 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Rose DP et al. Effects of linoleic acid and gamma-linolenic acid on the growth and metastasis of a human breast cancer cell line in nude mice and on its growth and invasive capacity in vitro. 1995 Nutr Cancer pmid:7491296
Murai A et al. Role of dietary gamma-linolenic acid in liver lipid metabolism in Japanese quail. 1995 Br. Poult. Sci. pmid:8746984
Sherrington EJ et al. The effect of dietary lipid manipulation on macrophage cell surface molecule expression. 1995 Biochem. Soc. Trans. pmid:7672298
Karasu C et al. Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids. 1995 Diabetologia pmid:7713308
Dines KC et al. Comparison of the effects of evening primrose oil and triglycerides containing gamma-linolenic acid on nerve conduction and blood flow in diabetic rats. 1995 J. Pharmacol. Exp. Ther. pmid:7714803
Giamarellos-Bourboulis EJ et al. In-vitro inhibitory activity of gamma-linolenic acid on Escherichia coli strains and its influence on their susceptibilities to various antimicrobial agents. 1995 J. Antimicrob. Chemother. pmid:8522462
Burgess NA et al. Evaluation of four animal models of intrarenal calcium deposition and assessment of the influence of dietary supplementation with essential fatty acids on calcification. 1995 Urol. Res. pmid:8533210
Harbige LS et al. Prevention of experimental autoimmune encephalomyelitis in Lewis rats by a novel fungal source of gamma-linolenic acid. 1995 Br. J. Nutr. pmid:8541276
Sture GH and Lloyd DH Canine atopic disease: therapeutic use of an evening primrose oil and fish oil combination. 1995 Vet. Rec. pmid:8553525
Rossetti RG et al. Differential regulation of human T lymphocyte protein kinase C activity by unsaturated fatty acids. 1995 Clin. Immunol. Immunopathol. pmid:7554442
Larsson-Backström C et al. Effects of dietary alpha- and gamma-linolenic acids on liver fatty acids, lipid metabolism, and survival in sepsis. 1995 Shock pmid:7552772
Das UN et al. Local application of gamma-linolenic acid in the treatment of human gliomas. 1995 Cancer Lett. pmid:7634242
Kietzmann M [Pharmacotherapeutic use of antipruritic drugs in skin diseases]. 1995 Tierarztl Prax pmid:7545832
Claassen N et al. Supplemented gamma-linolenic acid and eicosapentaenoic acid influence bone status in young male rats: effects on free urinary collagen crosslinks, total urinary hydroxyproline, and bone calcium content. 1995 Bone pmid:7626328
Manninen P et al. Separation of gamma- and alpha-linolenic acid containing triacylglycerols by capillary supercritical fluid chromatography. 1995 Lipids pmid:7564922
Akahane N et al. Antithrombotic activity of a symmetrical triglyceride with eicosapentaenoic acid and gamma-linolenic acid in guinea pig mesenteric microvasculature. 1995 Thromb. Res. pmid:7660360
Schoemaker JH Pharmacological treatment of diabetic peripheral neuropathy: challenges and possibilities. 1994 Mar-Apr Br J Clin Pract pmid:8024999
Hauben M Comment: evening primrose oil in the treatment of rheumatoid arthritis--proper application of statistical analysis. 1994 Jul-Aug Ann Pharmacother pmid:7832860
Fiocchi A et al. The efficacy and safety of gamma-linolenic acid in the treatment of infantile atopic dermatitis. 1994 Jan-Feb J. Int. Med. Res. pmid:7910570
BeLieu RM Mastodynia. 1994 Obstet. Gynecol. Clin. North Am. pmid:7816407
Berth-Jones J and Graham-Brown RA Evening primrose oil. Does not show promise in atopic dermatitis. 1994 BMJ pmid:7819863
Rubin M et al. Effect of three intravenously administered fat emulsions containing different concentrations of fatty acids on the plasma fatty acid composition of premature infants. 1994 J. Pediatr. pmid:7931881
Miller MA and Morgan RJ Eicosanoids, erections and erectile dysfunction. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7938091
Tulloch I et al. Evening primrose oil reduces urinary calcium excretion in both normal and hypercalciuric rats. 1994 Urol. Res. pmid:7871634
Purasiri P et al. Modulation of cytokine production in vivo by dietary essential fatty acids in patients with colorectal cancer. 1994 Clin. Sci. pmid:7874864
Stillwell W et al. Cholesterol condensation of alpha-linolenic and gamma-linolenic acid-containing phosphatidylcholine monolayers and bilayers. 1994 Biochim. Biophys. Acta pmid:7918592
Veale DJ et al. A double-blind placebo controlled trial of Efamol Marine on skin and joint symptoms of psoriatic arthritis. 1994 Br. J. Rheumatol. pmid:7921757
Darlington LG and Ramsey NW Review of dietary therapy for rheumatoid arthritis. 1994 Compr Ther pmid:7805365
Guivernau M et al. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7846101
McCaul JA and Lamey PJ Multiple oral mucoceles treated with gamma-linolenic acid: report of a case. 1994 Br J Oral Maxillofac Surg pmid:7849001
Christophe A et al. Effect of administration of gamma-linolenic acid on the fatty acid composition of serum phospholipids and cholesteryl esters in patients with cystic fibrosis. 1994 Ann. Nutr. Metab. pmid:8185286
du Toit PJ et al. Pyelonephritis: renal urokinase activity in rats on essential fatty acid diets. 1994 Urol. Res. pmid:7992455
de Kock M et al. Differential cytotoxic effects of gamma-linolenic acid on MG-63 and HeLa cells. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7972263
du Toit PJ et al. The effect of gamma-linolenic acid and eicosapentaenoic acid on urokinase activity. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7972265
Milner LS et al. Synergistic effects of fish oil diet and dimethylthiourea in acute adriamycin nephrosis. 1994 Am. J. Med. Sci. pmid:7977444
Bond R and Lloyd DH Combined treatment with concentrated essential fatty acids and prednisolone in the management of canine atopy. 1994 Vet. Rec. pmid:8135003
Phinney S Potential risk of prolonged gamma-linolenic acid use. 1994 Ann. Intern. Med. pmid:8135457
Chenoy R et al. Effect of oral gamolenic acid from evening primrose oil on menopausal flushing. 1994 BMJ pmid:8136666
Giamarellos-Bourboulis EJ et al. Do Escherichia coli susceptibilities to various antibiotics decrease in the presence of polyunsaturated fatty acids? A preliminary report. 1994 J Chemother pmid:8071677
Kirchgessner M et al. The effects of dietary oils on the fatty acid composition and osmotic fragility of rat erythrocytes. 1994 Z Ernahrungswiss pmid:8079509
Leventhal LJ et al. Treatment of rheumatoid arthritis with blackcurrant seed oil. 1994 Br. J. Rheumatol. pmid:8081671
Takada R et al. Dietary gamma-linolenic acid-enriched oil reduces body fat content and induces liver enzyme activities relating to fatty acid beta-oxidation in rats. 1994 J. Nutr. pmid:8145067
Morphake P et al. Alteration of cyclosporine (CsA)-induced nephrotoxicity by gamma linolenic acid (GLA) and eicosapentaenoic acid (EPA) in Wistar rats. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:8146206
Ramanathan R et al. Effects of gamma-linolenic acid, flavonoids, and vitamins on cytotoxicity and lipid peroxidation. 1994 Free Radic. Biol. Med. pmid:8299995
Maaswinkel-Mooij PD et al. Unsuccessful dietary treatment of Sjögren-Larsson syndrome. 1994 J. Pediatr. pmid:8176565
Wetzig NR Mastalgia: a 3 year Australian study. 1994 Aust N Z J Surg pmid:8179529
Biagi PL et al. The effect of gamma-linolenic acid on clinical status, red cell fatty acid composition and membrane microviscosity in infants with atopic dermatitis. 1994 Drugs Exp Clin Res pmid:7924900
Cameron NE and Cotter MA Effects of evening primrose oil treatment on sciatic nerve blood flow and endoneurial oxygen tension in streptozotocin-diabetic rats. 1994 Acta Diabetol pmid:7888693
Oliwiecki S and Burton JL Evening primrose oil and marine oil in the treatment of psoriasis. 1994 Clin. Exp. Dermatol. pmid:8050140
Kleijnen J Evening primrose oil. 1994 BMJ pmid:7950599