gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Fibrocystic Breast Disease D005348 1 associated lipids
Mucocele D009078 1 associated lipids
Salivary Gland Diseases D012466 1 associated lipids
Tietze's Syndrome D013991 1 associated lipids
Fallopian Tube Neoplasms D005185 1 associated lipids
Urolithiasis D052878 1 associated lipids
Scurvy D012614 2 associated lipids
Arthritis, Psoriatic D015535 3 associated lipids
Ecchymosis D004438 3 associated lipids
Pityriasis D010915 3 associated lipids
Carpal Tunnel Syndrome D002349 3 associated lipids
Carcinoma, Mucoepidermoid D018277 3 associated lipids
Mastocytoma D034801 3 associated lipids
Gastritis, Atrophic D005757 4 associated lipids
Hand Dermatoses D006229 5 associated lipids
Back Pain D001416 5 associated lipids
Intermittent Claudication D007383 6 associated lipids
Xerostomia D014987 6 associated lipids
Bacteriuria D001437 7 associated lipids
Raynaud Disease D011928 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Belch JJ and Hill A Evening primrose oil and borage oil in rheumatologic conditions. 2000 Am. J. Clin. Nutr. pmid:10617996
Head RJ et al. Prevention of nerve conduction deficit in diabetic rats by polyunsaturated fatty acids. 2000 Am. J. Clin. Nutr. pmid:10618002
Schwartz J Role of polyunsaturated fatty acids in lung disease. 2000 Am. J. Clin. Nutr. pmid:10618003
Burke A et al. Specific analysis in plasma and urine of 2,3-dinor-5, 6-dihydro-isoprostane F(2alpha)-III, a metabolite of isoprostane F(2alpha)-III and an oxidation product of gamma-linolenic acid. 2000 J. Biol. Chem. pmid:10644705
Palombo JD et al. Comparison of growth and fatty acid metabolism in rats fed diets containing equal levels of gamma-linolenic acid from high gamma-linolenic acid canola oil or borage oil. 2000 Lipids pmid:11026618
Fokkema MR et al. Short-term supplementation of low-dose gamma-linolenic acid (GLA), alpha-linolenic acid (ALA), or GLA plus ALA does not augment LCP omega 3 status of Dutch vegans to an appreciable extent. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11090255
Worm M and Henz BM Novel unconventional therapeutic approaches to atopic eczema. 2000 Dermatology (Basel) pmid:11096188
Harbige LS et al. The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-beta1) up-regulation and increased prostaglandin E2 (PGE2) production. 2000 Clin. Exp. Immunol. pmid:11122253
Horner NK and Lampe JW Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness. 2000 J Am Diet Assoc pmid:11103660
Pakala R et al. Vascular smooth muscle cells preloaded with eicosapentaenoic acid and docosahexaenoic acid fail to respond to serotonin stimulation. 2000 Atherosclerosis pmid:11058699
Vinik AI et al. Diabetic neuropathies. 2000 Diabetologia pmid:10990072
Iijima S et al. Oral supplementation with gamma-linolenic acid extracted from Mucor circinelloides improves the deformability of red blood cells in hemodialysis patients. 2000 Nephron pmid:11014980
Arnold LE et al. Does zinc moderate essential fatty acid and amphetamine treatment of attention-deficit/hyperactivity disorder? 2000 J Child Adolesc Psychopharmacol pmid:10933121
Guil-Guerrero JL et al. Occurrence and characterization of oils rich in gamma-linolenic acid part II: fatty acids and squalene from Macaronesian Echium leaves. 2000 Phytochemistry pmid:10939357
Liu QY and Tan BK Effects of cis-unsaturated fatty acids on doxorubicin sensitivity in P388/DOX resistant and P388 parental cell lines. 2000 Life Sci. pmid:10954054
Parker-Barnes JM et al. Identification and characterization of an enzyme involved in the elongation of n-6 and n-3 polyunsaturated fatty acids. 2000 Proc. Natl. Acad. Sci. U.S.A. pmid:10899997
Rahbeeni F et al. The effect of evening primrose oil on the radiation response and blood flow of mouse normal and tumour tissue. 2000 Int. J. Radiat. Biol. pmid:10902742
Kapoor R and Klimaszewski A Efficacy of borage oil in patients with atopic eczema. 2000 Br. J. Dermatol. pmid:10886164
Simán CM et al. Failure of short-term gamma-linolenic acid treatment to reduce urinary calcium loss of diabetic rats. 2000 Urol. Res. pmid:10850637
Murray MJ et al. Effects of eicosapentaenoic and gamma-linolenic acids (dietary lipids) on pulmonary surfactant composition and function during porcine endotoxemia. 2000 Chest pmid:10858408
Oguogho A et al. Prostaglandin synthesis in human lymphatics from precursor fatty acids. 2000 Lymphology pmid:10897472
Barham JB et al. Addition of eicosapentaenoic acid to gamma-linolenic acid-supplemented diets prevents serum arachidonic acid accumulation in humans. 2000 J. Nutr. pmid:10917903
Kenny FS et al. Gamma linolenic acid with tamoxifen as primary therapy in breast cancer. 2000 Int. J. Cancer pmid:10699943
Ravichandran D et al. Effect of 1-(gamma)linolenyl-3-eicosapentaenoyl propane diol on the growth of human pancreatic carcinoma in vitro and in vivo. 2000 Eur. J. Cancer pmid:10708945
Thijs C et al. Essential fatty acids in breast milk of atopic mothers: comparison with non-atopic mothers, and effect of borage oil supplementation. 2000 Eur J Clin Nutr pmid:10713746
Guil-Guerrero JL et al. Occurrence and characterization of oils rich in gamma-linolenic acid Part I: Echium seeds from Macaronesia. 2000 Phytochemistry pmid:10731022
Hindo J et al. Evidence of the formation of different hydroperoxides in irradiated gamma-linolenate solutions: effect of micelle formation. 2000 Radiat. Res. pmid:10629620
Takahashi Y et al. Dietary gamma-linolenic acid in the form of borage oil causes less body fat accumulation accompanying an increase in uncoupling protein 1 mRNA level in brown adipose tissue. 2000 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11079375
Kumar KV et al. Oxidant stress and essential fatty acids in patients with risk and established ARDS. 2000 Clin. Chim. Acta pmid:10876008
Beaudoin F et al. Production of C20 polyunsaturated fatty acids (PUFAs) by pathway engineering: identification of a PUFA elongase component from Caenorhabditis elegans. 2000 Biochem. Soc. Trans. pmid:11171161
Shahidi F Antioxidant factors in plant foods and selected oilseeds. 2000 Biofactors pmid:11237180
Horrobin DF Essential fatty acid metabolism and its modification in atopic eczema. 2000 Am. J. Clin. Nutr. pmid:10617999
Cohen SM et al. Therapeutic use of selected herbs. 2000 Holist Nurs Pract pmid:12119629
Petrik MB et al. Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. 2000 J. Nutr. pmid:11015469
Dove D and Johnson P Oral evening primrose oil: its effect on length of pregnancy and selected intrapartum outcomes in low-risk nulliparous women. 1999 May-Jun J Nurse Midwifery pmid:10380450
De Antueno R et al. Tissue distribution and metabolism of gamma-linolenoyl-3-eicosapentaenoyl propane diol enterally or intravenously administered to mice bearing human pancreatic carcinomas. 1999 May-Jun Anticancer Res. pmid:10470146
Zurier RB et al. Human peripheral blood T lymphocyte proliferation after activation of the T cell receptor: effects of unsaturated fatty acids. 1999 May-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:10471124
Srinivas CV et al. Safflower petals: a source of gamma linolenic acid. 1999 Plant Foods Hum Nutr pmid:10646633
Hornych A et al. Effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandins in old subjects. 1999 Br J Clin Pharmacol pmid:10651470
Harris JE et al. Five-lipoxygenase inhibitors reduce Panc-1 survival: synergism of MK886 with gamma linolenic acid. 1999 Adv. Exp. Med. Biol. pmid:10667375
Ramrath S et al. Stimulation of cardiac glucose transport by thioctic acid and insulin. 1999 Horm. Metab. Res. pmid:10668913
Motaung E et al. Cytotoxicity of combined essential fatty acids on a human prostate cancer cell line. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10670696
Davies CL et al. Effect of gamma-linolenic acid on cellular uptake of structurally related anthracyclines in human drug sensitive and multidrug resistant bladder and breast cancer cell lines. 1999 Eur. J. Cancer pmid:10673983
Cai J et al. Inhibition of angiogenic factor- and tumour-induced angiogenesis by gamma linolenic acid. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10319914
Warren G et al. The role of essential fatty acids in chronic fatigue syndrome. A case-controlled study of red-cell membrane essential fatty acids (EFA) and a placebo-controlled treatment study with high dose of EFA. 1999 Acta Neurol. Scand. pmid:10071170
Muñoz SE et al. Differential effects of dietary Oenothera, Zizyphus mistol, and corn oils, and essential fatty acid deficiency on the progression of a murine mammary gland adenocarcinoma. 1999 Nutrition pmid:10198915
Tamimi NA et al. Role of gamma-linolenic acid in uraemic pruritus. 1999 Nephron pmid:10516500
Wu D et al. Effect of dietary supplementation with black currant seed oil on the immune response of healthy elderly subjects. 1999 Am. J. Clin. Nutr. pmid:10500023
Pirich C et al. Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. 1999 Thromb. Res. pmid:10588465
Redden PR et al. Acyloxymethyl acidic drug derivatives: in vitro hydrolytic reactivity. 1999 Int J Pharm pmid:10370185