| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Pakala R et al. | Eicosapentaenoic acid and docosahexaenoic acid selectively attenuate U46619-induced smooth muscle cell proliferation. | 1999 | Lipids | pmid:10574655 |
| Stahl A et al. | Identification of the major intestinal fatty acid transport protein. | 1999 | Mol. Cell | pmid:10518211 |
| Ward GR et al. | Effects of gamma-linolenic acid and docosahexaenoic acid in formulae on brain fatty acid composition in artificially reared rats. | 1999 | Lipids | pmid:10580333 |
| Joubert AM et al. | Comparative study of the effects of polyunsaturated fatty acids and their metabolites on cell growth and tyrosine kinase activity in oesophageal carcinoma cells. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10582657 |
| Bell HS et al. | Effects of N-6 essential fatty acids on glioma invasion and growth: experimental studies with glioma spheroids in collagen gels. | 1999 | J. Neurosurg. | pmid:10584845 |
| Srinivas CV et al. | Safflower petals: a source of gamma linolenic acid. | 1999 | Plant Foods Hum Nutr | pmid:10646633 |
| Hornych A et al. | Effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandins in old subjects. | 1999 | Br J Clin Pharmacol | pmid:10651470 |
| Fan YY et al. | Modulation of atherogenesis by dietary gamma-linolenic acid. | 1999 | Adv. Exp. Med. Biol. | pmid:10667372 |
| Vartak S et al. | The selective cytotoxicity of gamma-linolenic acid (GLA) is associated with increased oxidative stress. | 1999 | Adv. Exp. Med. Biol. | pmid:10667373 |
| Robbins M et al. | gamma-linolenic acid (GLA)-mediated cytotoxicity in human prostate cancer cells. | 1999 | Adv. Exp. Med. Biol. | pmid:10667374 |
| Harris JE et al. | Five-lipoxygenase inhibitors reduce Panc-1 survival: synergism of MK886 with gamma linolenic acid. | 1999 | Adv. Exp. Med. Biol. | pmid:10667375 |
| Ramrath S et al. | Stimulation of cardiac glucose transport by thioctic acid and insulin. | 1999 | Horm. Metab. Res. | pmid:10668913 |
| Motaung E et al. | Cytotoxicity of combined essential fatty acids on a human prostate cancer cell line. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10670696 |
| Davies CL et al. | Effect of gamma-linolenic acid on cellular uptake of structurally related anthracyclines in human drug sensitive and multidrug resistant bladder and breast cancer cell lines. | 1999 | Eur. J. Cancer | pmid:10673983 |
| Cai J et al. | Inhibition of angiogenic factor- and tumour-induced angiogenesis by gamma linolenic acid. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10319914 |
| Ihara-Watanabe M et al. | Effects of dietary alpha- or gamma-linolenic acid on levels and fatty acid compositions of serum and hepatic lipids, and activity and mRNA abundance of 3-hydroxy-3-methylglutaryl CoA reductase in rats. | 1999 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:10327618 |
| Giamarellos-Bourboulis EJ et al. | In vitro interactions of gamma-linolenic acid and arachidonic acid with ceftazidime on multiresistant Pseudomonas aeruginosa. | 1999 | Lipids | pmid:10419130 |
| Cai J et al. | Inhibition of the expression of VE-cadherin/catenin complex by gamma linolenic acid in human vascular endothelial cells, and its impact on angiogenesis. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10222244 |
| Leaver HA et al. | Dynamics of reactive oxygen intermediate production in human glioma: n-6 essential fatty acid effects. | 1999 | Eur. J. Clin. Invest. | pmid:10202379 |
| Warren G et al. | The role of essential fatty acids in chronic fatigue syndrome. A case-controlled study of red-cell membrane essential fatty acids (EFA) and a placebo-controlled treatment study with high dose of EFA. | 1999 | Acta Neurol. Scand. | pmid:10071170 |
| Muñoz SE et al. | Differential effects of dietary Oenothera, Zizyphus mistol, and corn oils, and essential fatty acid deficiency on the progression of a murine mammary gland adenocarcinoma. | 1999 | Nutrition | pmid:10198915 |
| Tamimi NA et al. | Role of gamma-linolenic acid in uraemic pruritus. | 1999 | Nephron | pmid:10516500 |
| Wu D et al. | Effect of dietary supplementation with black currant seed oil on the immune response of healthy elderly subjects. | 1999 | Am. J. Clin. Nutr. | pmid:10500023 |
| Peterson LD et al. | Dose-dependent effects of dietary gamma-linolenic acid on rat spleen lymphocyte functions. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10477037 |
| Haag M et al. | Polyunsaturated fatty acids inhibit Mg2+ -ATPase in basolateral membranes from rat enterocytes. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10477038 |
| Huang YS et al. | Cloning of delta12- and delta6-desaturases from Mortierella alpina and recombinant production of gamma-linolenic acid in Saccharomyces cerevisiae. | 1999 | Lipids | pmid:10478922 |
| Cheung KL | Management of cyclical mastalgia in oriental women: pioneer experience of using gamolenic acid (Efamast) in Asia. | 1999 | Aust N Z J Surg | pmid:10442919 |
| De La Cruz JP et al. | Antioxidant potential of evening primrose oil administration in hyperlipemic rabbits. | 1999 | Life Sci. | pmid:10462081 |
| Schwartz Z et al. | Arachidonic acid directly mediates the rapid effects of 24,25-dihydroxyvitamin D3 via protein kinase C and indirectly through prostaglandin production in resting zone chondrocytes. | 1999 | Endocrinology | pmid:10385391 |
| Henz BM et al. | Double-blind, multicentre analysis of the efficacy of borage oil in patients with atopic eczema. | 1999 | Br. J. Dermatol. | pmid:10233322 |
| Likhodii SS and Cunnane SC | Uptake of 13C-tracer arachidonate and gamma-linolenate by the brain and liver of the suckling rat observed using 13C-NMR. | 1999 | J. Neurochem. | pmid:10349866 |
| Yoshimoto-Furuie K et al. | Effects of oral supplementation with evening primrose oil for six weeks on plasma essential fatty acids and uremic skin symptoms in hemodialysis patients. | 1999 | Nephron | pmid:9933750 |
| Khamaisi M et al. | Metabolic effects of gamma-linolenic acid-alpha-lipoic acid conjugate in streptozotocin diabetic rats. | 1999 | Antioxid. Redox Signal. | pmid:11233149 |
| Murakami K et al. | Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403814 |
| Pirich C et al. | Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. | 1999 | Thromb. Res. | pmid:10588465 |
| Redden PR et al. | Acyloxymethyl acidic drug derivatives: in vitro hydrolytic reactivity. | 1999 | Int J Pharm | pmid:10370185 |
| Burnard SL et al. | Cilazapril and dietary gamma-linolenic acid prevent the deficit in sciatic nerve conduction velocity in the streptozotocin diabetic rat. | 1998 Mar-Apr | J. Diabetes Complicat. | pmid:9559483 |
| Anderson KM et al. | Five-lipoxygenase inhibitors reduce Panc-1 survival: the mode of cell death and synergism of MK886 with gamma linolenic acid. | 1998 Mar-Apr | Anticancer Res. | pmid:9615721 |
| Oakley OR et al. | The effects of lithium gamma-linolenic acid in reversing LPBM5 MuLV induced suppression of hematopoietic progenitor cells in vitro. | 1998 Jan-Jun | Rom J Physiol | pmid:11000861 |
| Frati-Munari AC and Ariza-Andraca CR | [Treatment of diabetic neuropathy]. | 1998 Jan-Feb | Gac Med Mex | pmid:9658700 |
| Willemaers V et al. | [Atopic dermatitis]. | 1998 | Rev Med Liege | pmid:9564223 |
| Hørby Jørgensen M et al. | Effect of formula supplemented with docosahexaenoic acid and gamma-linolenic acid on fatty acid status and visual acuity in term infants. | 1998 | J. Pediatr. Gastroenterol. Nutr. | pmid:9552137 |
| Solomon LZ et al. | Is gamma-linolenic acid an effective intravesical agent for superficial bladder cancer? In vitro cytotoxicity and in vivo tolerance studies. | 1998 | Urol. Res. | pmid:9537690 |
| Kis M et al. | Light-induced expression of fatty acid desaturase genes. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9539715 |
| Cameron NE et al. | Effects of alpha-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids. | 1998 | Diabetologia | pmid:9562342 |
| Eynard AR et al. | Eicosatrienoic acid (20:3 n-9) inhibits the expression of E-cadherin and desmoglein in human squamous cell carcinoma in vitro. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10102382 |
| Brouwer DA et al. | Gamma-linolenic acid does not augment long-chain polyunsaturated fatty acid omega-3 status. | 1998 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9888208 |
| Leng GC et al. | Randomized controlled trial of gamma-linolenic acid and eicosapentaenoic acid in peripheral arterial disease. | 1998 | Clin Nutr | pmid:10205349 |
| Hounsom L et al. | A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy. | 1998 | Diabetologia | pmid:9686927 |
| Kumamoto T and Ide T | Comparative effects of alpha- and gamma-linolenic acids on rat liver fatty acid oxidation. | 1998 | Lipids | pmid:9688166 |