| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Seizures | D012640 | 87 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Atherosclerosis | D050197 | 85 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ziboh VA and Fletcher MP | Dose-response effects of dietary gamma-linolenic acid-enriched oils on human polymorphonuclear-neutrophil biosynthesis of leukotriene B4. | 1992 | Am. J. Clin. Nutr. | pmid:1309474 |
| Mimouni V et al. | Evidence for insulin dependent hepatic microsomal gamma-linolenic acid chain elongation in spontaneously diabetic Wistar BB rats. | 1992 | Biochim. Biophys. Acta | pmid:1310052 |
| St Louis C et al. | Antihypertensive effect of gamma-linolenic acid in spontaneously hypertensive rats. | 1992 | Hypertension | pmid:1310479 |
| Bond R and Lloyd DH | A double-blind comparison of olive oil and a combination of evening primrose oil and fish oil in the management of canine atopy. | 1992 | Vet. Rec. | pmid:1481346 |
| Howie A et al. | The influence of dietary essential fatty acids on uterine C20 and C22 fatty acid composition. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1502249 |
| Navarette R et al. | Dietary intake of concentrated gamma-linolenic acid (GLA)-enriched oil suppresses cutaneous level of dihomo-gamma-linolenic acid (DGLA): possible in vivo inhibition of microsomal elongation of GLA to DGLA. | 1992 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:1323857 |
| Nassar BA et al. | The effect of chemical hepatocarcinogenesis on liver phospholipid composition in rats fed N-6 and N-3 fatty acid-supplemented diets. | 1992 | Proc. Soc. Exp. Biol. Med. | pmid:1539039 |
| Jenkins AP et al. | Effects of bolus doses of fat on small intestinal structure and on release of gastrin, cholecystokinin, peptide tyrosine-tyrosine, and enteroglucagon. | 1992 | Gut | pmid:1541417 |
| Jenkins AP and Thompson RP | Effect of dietary fat on the distribution of mucosal mass and cell proliferation along the small intestine. | 1992 | Gut | pmid:1541418 |
| Ergan F et al. | Lipase specificity against some fatty acids? | 1992 | Ann. N. Y. Acad. Sci. | pmid:1335712 |
| Oon BB et al. | A diet enriched in essential fatty acids protects against the loss of lymphocytes which occurs in rats suffering from streptozotocin-induced diabetes. | 1992 | Exp. Physiol. | pmid:1543584 |
| Furuse M et al. | Effect of gamma-linolenic acid on lipid metabolism in laying hens. | 1992 | Comp Biochem Physiol A Comp Physiol | pmid:1347726 |
| Ormerod LD et al. | Eicosanoid modulation and epithelial wound healing kinetics of the alkali-burned cornea. | 1992 | J Ocul Pharmacol | pmid:1328428 |
| Barre DE and Holub BJ | The effect of borage oil consumption on the composition of individual phospholipids in human platelets. | 1992 | Lipids | pmid:1328794 |
| Duffy O et al. | Attenuation of the effects of chronic ethanol administration in the brain lipid content of the developing rat by an oil enriched in gamma linolenic acid. | 1992 | Drug Alcohol Depend | pmid:1330473 |
| Hamberg M | Metabolism of 6,9,12-octadecatrienoic acid in the red alga Lithothamnion corallioides: mechanism of formation of a conjugated tetraene fatty acid. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1332713 |
| Gunstone FD | Gamma linolenic acid--occurrence and physical and chemical properties. | 1992 | Prog. Lipid Res. | pmid:1334265 |
| Horrobin DF | Nutritional and medical importance of gamma-linolenic acid. | 1992 | Prog. Lipid Res. | pmid:1334266 |
| Engler MM et al. | Dietary gamma-linolenic acid lowers blood pressure and alters aortic reactivity and cholesterol metabolism in hypertension. | 1992 | J. Hypertens. | pmid:1335001 |
| McFayden IJ et al. | Cyclical breast pain--some observations and the difficulties in treatment. | 1992 | Br J Clin Pract | pmid:1286012 |
| Hayashi Y et al. | Anticancer effects of free polyunsaturated fatty acids in an oily lymphographic agent following intrahepatic arterial administration to a rabbit bearing VX-2 tumor. | 1992 | Cancer Res. | pmid:1309442 |
| Dobbin SN | Evening primrose oil and epilepsy. | 1992 Dec 19-26 | Vet. Rec. | pmid:1287960 |
| Takeda S et al. | Lipid peroxidation in human breast cancer cells in response to gamma-linolenic acid and iron. | 1992 Mar-Apr | Anticancer Res. | pmid:1316091 |
| Söreide E et al. | Long-term use of gamma-linolenic acid-enriched fat emulsion (PFE 4501): case report. | 1992 May-Jun | Nutrition | pmid:1326350 |
| Cantrill RC et al. | The effect of n-6 fatty acids on normal and v-Ki ras transformed NIH-3T3 cells. | 1992 Nov-Dec | Anticancer Res. | pmid:1338278 |
| Tollesson A and Frithz A | Transepidermal water loss and water content in the stratum corneum in infantile seborrhoeic dermatitis. | 1993 | Acta Derm. Venereol. | pmid:8095744 |
| Berth-Jones J and Graham-Brown RA | Placebo-controlled trial of essential fatty acid supplementation in atopic dermatitis. | 1993 | Lancet | pmid:8099640 |
| Dines KC et al. | Contrasting effects of treatment with omega-3 and omega-6 essential fatty acids on peripheral nerve function and capillarization in streptozotocin-diabetic rats. | 1993 | Diabetologia | pmid:8270127 |
| Laivuori H et al. | Dietary supplementation with primrose oil or fish oil does not change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8248275 |
| Stevens EJ et al. | Prostacyclin release in experimental diabetes: effects of evening primrose oil. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8248277 |
| Leyton E | Disagreeing on how to treat CFS patients. | 1993 | Can Fam Physician | pmid:8347205 |
| Leventhal LJ et al. | Treatment of rheumatoid arthritis with gammalinolenic acid. | 1993 | Ann. Intern. Med. | pmid:8214997 |
| Karlstad MD et al. | Effect of intravenous lipid emulsions enriched with gamma-linolenic acid on plasma n-6 fatty acids and prostaglandin biosynthesis after burn and endotoxin injury in rats. | 1993 | Crit. Care Med. | pmid:8222692 |
| Harvey RG | Effect of varying proportions of evening primrose oil and fish oil on cats with crusting dermatosis ('miliary dermatitis') | 1993 | Vet. Rec. | pmid:8280288 |
| Engler MM | Comparative study of diets enriched with evening primrose, black currant, borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8259378 |
| Harvey RG | A comparison of evening primrose oil and sunflower oil for the management of papulocrustous dermatitis in cats. | 1993 | Vet. Rec. | pmid:8303807 |
| Stevens EJ et al. | Essential fatty acid treatment prevents nerve ischaemia and associated conduction anomalies in rats with experimental diabetes mellitus. | 1993 | Diabetologia | pmid:8314443 |
| Joe LA and Hart LL | Evening primrose oil in rheumatoid arthritis. | 1993 | Ann Pharmacother | pmid:8305783 |
| Keen H et al. | Treatment of diabetic neuropathy with gamma-linolenic acid. The gamma-Linolenic Acid Multicenter Trial Group. | 1993 | Diabetes Care | pmid:8380765 |
| Horrobin DF | The effects of gamma-linolenic acid on breast pain and diabetic neuropathy: possible non-eicosanoid mechanisms. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8380930 |
| Hopewell JW et al. | The modulation of radiation-induced damage to pig skin by essential fatty acids. | 1993 | Br. J. Cancer | pmid:8391301 |
| Cerin A et al. | Hormonal and biochemical profiles of premenstrual syndrome. Treatment with essential fatty acids. | 1993 | Acta Obstet Gynecol Scand | pmid:8392261 |
| Galle AM et al. | Biosynthesis of gamma-linolenic acid in developing seeds of borage (Borago officinalis L.). | 1993 | Biochim. Biophys. Acta | pmid:8394742 |
| Kinchington D et al. | Lithium gamma-linolenate-induced cytotoxicity against cells chronically infected with HIV-1. | 1993 | FEBS Lett. | pmid:8396048 |
| Bala KV et al. | Inhibition of methyl mercury chloride-induced chromosomal damage by gamma-linolenic acid. | 1993 | Food Chem. Toxicol. | pmid:8390392 |
| Oliwiecki S et al. | The effect of essential fatty acids on epidermal atrophy due to topical steroids. | 1993 | Clin. Exp. Dermatol. | pmid:8403467 |
| Melnik B and Plewig G | [External treatment of atopic eczema with gamma-linolenic acid?]. | 1993 | Hautarzt | pmid:8407331 |
| Beno DW et al. | Gamma-linolenic acid suppression of hepatic Ito cell mitogenesis: post-PDGF receptor prostaglandin-independent mechanism. | 1993 | Am. J. Physiol. | pmid:7694498 |
| Cantrill RC et al. | Concentration-dependent effect of iron on gamma-linolenic acid toxicity in ZR-75-1 human breast tumor cells in culture. | 1993 | Cancer Lett. | pmid:8402582 |
| Thurmond DC et al. | Time-dependent effects of progressive gamma-linolenate feeding on hyperphagia, weight gain, and erythrocyte fatty acid composition during growth of Zucker obese rats. | 1993 | Obes. Res. | pmid:16353349 |