| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Gastritis | D005756 | 27 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Kidney Calculi | D007669 | 7 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Frenoux JM et al. | A polyunsaturated fatty acid diet lowers blood pressure and improves antioxidant status in spontaneously hypertensive rats. | 2001 | J. Nutr. | pmid:11208936 |
| OlguÃn EJ et al. | The effect of low light flux and nitrogen deficiency on the chemical composition of Spirulina sp. (Arthrospira) grown on digested pig waste. | 2001 | Bioresour. Technol. | pmid:11211071 |
| Corbett JW et al. | Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11212098 |
| Khamaisi M et al. | Metabolic effects of gamma-linolenic acid-alpha-lipoic acid conjugate in streptozotocin diabetic rats. | 1999 | Antioxid. Redox Signal. | pmid:11233149 |
| Shahidi F | Antioxidant factors in plant foods and selected oilseeds. | 2000 | Biofactors | pmid:11237180 |
| Agostoni C et al. | Biochemical effects of supplemented long-chain polyunsaturated fatty acids in hyperphenylalaninemia. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11237478 |
| Thies F et al. | Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n-3 or n-6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y. | 2001 | Am. J. Clin. Nutr. | pmid:11237929 |
| Menéndez JA et al. | Effects of gamma-linolenic acid and oleic acid on paclitaxel cytotoxicity in human breast cancer cells. | 2001 | Eur. J. Cancer | pmid:11239764 |
| Borenshtein D et al. | Cataract development in diabetic sand rats treated with alpha-lipoic acid and its gamma-linolenic acid conjugate. | 2001 Jan-Feb | Diabetes Metab. Res. Rev. | pmid:11241890 |
| Keysser G | [Are there effective dietary recommendations for patients with rheumatoid arthritis?]. | 2001 | Z Rheumatol | pmid:11263011 |
| Little C and Parsons T | Herbal therapy for treating rheumatoid arthritis. | 2001 | Cochrane Database Syst Rev | pmid:11279784 |
| Kenny FS et al. | Effect of dietary GLA+/-tamoxifen on the growth, ER expression and fatty acid profile of ER positive human breast cancer xenografts. | 2001 | Int. J. Cancer | pmid:11291069 |
| Kaku S et al. | Interactions of dietary fats and proteins on fatty acid composition of immune cells and LTB4 production by peritoneal exudate cells of rats. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11302164 |
| Sims EC and Plowman PN | Stereotactic radiosurgery XII. Large AVM and the failure of the radiation response modifier gamma linolenic acid to improve the therapeutic ratio. | 2001 | Br J Neurosurg | pmid:11303657 |
| Fauconnot L and Buist PH | Gamma-linolenic acid biosynthesis: cryptoregiochemistry of delta6 desaturation. | 2001 | J. Org. Chem. | pmid:11312950 |
| Mpanju O et al. | Selective cytotoxicity of lithium gamma-linolenic acid in human T cells chronically and productively infected with HIV. | 1997 | Antivir. Ther. (Lond.) | pmid:11322262 |
| Colquhoun A and Schumacher RI | Modifications in mitochondrial metabolism and ultrastructure and their relationship to tumour growth inhibition by gamma-linolenic acid. | 2001 | Mol. Cell. Biochem. | pmid:11330827 |
| Hrelia S et al. | Role of gamma-linolenic acid in counteracting doxorubicin-induced damage in cultured rat cardiomyocytes. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11334548 |
| Hounsom L et al. | Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy. | 2001 | Diabetologia | pmid:11357471 |
| Barre DE | Potential of evening primrose, borage, black currant, and fungal oils in human health. | 2001 | Ann. Nutr. Metab. | pmid:11359029 |
| Fuller MA et al. | Activity of soybean lipoxygenase isoforms against esterified fatty acids indicates functional specificity. | 2001 | Arch. Biochem. Biophys. | pmid:11361131 |
| Fan YY et al. | Dietary gamma-linolenic acid suppresses aortic smooth muscle cell proliferation and modifies atherosclerotic lesions in apolipoprotein E knockout mice. | 2001 | J. Nutr. | pmid:11385052 |
| Nwankwo JO | Repression of cellular anaplerosis as the hypothesized mechanism of gamma-linolenic acid-induced toxicity to tumor cells. | 2001 | Med. Hypotheses | pmid:11388772 |
| Nwankwo JO and Robbins ME | Peroxisome proliferator-activated receptor- gamma expression in human malignant and normal brain, breast and prostate-derived cells. | 2001 Apr-May | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11418018 |
| Furse RK et al. | Gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, blocks amplification of IL-1 beta production by human monocytes. | 2001 | J. Immunol. | pmid:11418687 |
| Kankaanpää P et al. | Polyunsaturated fatty acids in maternal diet, breast milk, and serum lipid fatty acids of infants in relation to atopy. | 2001 | Allergy | pmid:11421921 |
| Kamphuis MM et al. | Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid. | 2001 | Eur J Clin Nutr | pmid:11423927 |
| Mainou-Fowler T et al. | Gamma-linolenic acid induces apoptosis in B-chronic lymphocytic leukaemia cells in vitro. | 2001 | Leuk. Lymphoma | pmid:11426562 |
| Chakrabarti KB et al. | Modification of doxorubicin-induced cardiotoxicity: effect of essential fatty acids and ICRF-187 (dexrazoxane). | 2001 | Eur. J. Cancer | pmid:11435077 |
| Thies F et al. | Dietary supplementation with gamma-linolenic acid or fish oil decreases T lymphocyte proliferation in healthy older humans. | 2001 | J. Nutr. | pmid:11435508 |
| Yogo Y and Fujishima S | [Nutritional support for ARDS]. | 2001 | Nippon Rinsho | pmid:11439576 |
| Serrano I et al. | Ethanol-induced dimorphism and lipid composition changes in Mucor fragilis CCMI 142. | 2001 | Lett. Appl. Microbiol. | pmid:11442823 |
| Hou X et al. | 2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite. | 2001 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11448840 |
| Ford I et al. | The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat. | 2001 | Metab. Clin. Exp. | pmid:11474472 |
| Cunnane SC et al. | NMR and isotope ratio mass spectrometry studies of in vivo uptake and metabolism of polyunsaturates by the developing rat brain. | 2001 Apr-Jun | J. Mol. Neurosci. | pmid:11478372 |
| Demmelmair H et al. | Influence of formulas with borage oil or borage oil plus fish oil on the arachidonic acid status in premature infants. | 2001 | Lipids | pmid:11485158 |
| Guil-Guerrero JL et al. | Occurrence and characterization of oils rich in gamma-linolenic acid (III): the taxonomical value of the fatty acids in Echium (Boraginaceae). | 2001 | Phytochemistry | pmid:11524120 |
| Birch AE et al. | Antioxidant properties of evening primrose seed extracts. | 2001 | J. Agric. Food Chem. | pmid:11559161 |
| Ide T et al. | Dietary mold oil rich in gamma linolenic acid increases insulin-dependent glucose utilization in isolated rat adipocytes. | 2001 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:11567903 |
| Zavodnik LB et al. | [Effect of gamma-linolenic acid on microsomal oxidation in the rat liver following gamma-irradiation]. | 2001 Jul-Aug | Eksp Klin Farmakol | pmid:11589114 |
| Reinikainen M et al. | The toxicities of a polyunsaturated fatty acid and a microcystin to Daphnia magna. | 2001 | Environ. Toxicol. | pmid:11594032 |
| Agatha G et al. | Fatty acid composition of lymphocyte membrane phospholipids in children with acute leukemia. | 2001 | Cancer Lett. | pmid:11597788 |
| Wollheim FA | [Meager support for herbal therapy of rheumatoid arthritis]. | 2001 | Lakartidningen | pmid:11699249 |
| Kast RE | Borage oil reduction of rheumatoid arthritis activity may be mediated by increased cAMP that suppresses tumor necrosis factor-alpha. | 2001 | Int. Immunopharmacol. | pmid:11710548 |
| Kaku S et al. | Dietary gamma-linolenic acid dose-dependently modifies fatty acid composition and immune parameters in rats. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728173 |
| Colquhoun A and Schumacher RI | gamma-Linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells. | 2001 | Biochim. Biophys. Acta | pmid:11731331 |
| Tsimaratos M et al. | Gamma-linolenic acid restores renal medullary thick ascending limb Na(+),K(+)-ATPase activity in diabetic rats. | 2001 | J. Nutr. | pmid:11739860 |
| Keegan A et al. | Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment. | 2001 Sep-Oct | Diabetes Metab. Res. Rev. | pmid:11747143 |
| OtleÅŸ S and Pire R | Fatty acid composition of Chlorella and Spirulina microalgae species. | 2001 Nov-Dec | J AOAC Int | pmid:11767135 |
| Deng X et al. | Regulation of the rat SREBP-1c promoter in primary rat hepatocytes. | 2002 | Biochem. Biophys. Res. Commun. | pmid:11779162 |