| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Gastritis | D005756 | 27 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Osteosarcoma | D012516 | 50 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Kidney Calculi | D007669 | 7 associated lipids |
gamma-Linolenic acid
Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
Cross Reference
Introduction
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
PubChem Associated disorders and diseases
What pathways are associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with gamma-Linolenic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with gamma-Linolenic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
What common seen animal models are associated with gamma-Linolenic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with gamma-Linolenic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fuller MA et al. | Activity of soybean lipoxygenase isoforms against esterified fatty acids indicates functional specificity. | 2001 | Arch. Biochem. Biophys. | pmid:11361131 |
| Kamphuis MM et al. | Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid. | 2001 | Eur J Clin Nutr | pmid:11423927 |
| Chakrabarti KB et al. | Modification of doxorubicin-induced cardiotoxicity: effect of essential fatty acids and ICRF-187 (dexrazoxane). | 2001 | Eur. J. Cancer | pmid:11435077 |
| Banni S et al. | Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland. | 2001 | Nutr Cancer | pmid:12094634 |
| OlguÃn EJ et al. | The effect of low light flux and nitrogen deficiency on the chemical composition of Spirulina sp. (Arthrospira) grown on digested pig waste. | 2001 | Bioresour. Technol. | pmid:11211071 |
| Goffman FD and Galletti S | Gamma-linolenic acid and tocopherol contents in the seed oil of 47 accessions from several Ribes species. | 2001 | J. Agric. Food Chem. | pmid:11170598 |
| Conti E et al. | gamma-Linolenic acid production by solid-state fermentation of Mucorales strains on cereals. | 2001 | Bioresour. Technol. | pmid:11198184 |
| Keysser G | [Are there effective dietary recommendations for patients with rheumatoid arthritis?]. | 2001 | Z Rheumatol | pmid:11263011 |
| Biessels GJ et al. | The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. | 2001 | J. Neurol. Sci. | pmid:11137514 |
| Corbett JW et al. | Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11212098 |
| Agostoni C et al. | Biochemical effects of supplemented long-chain polyunsaturated fatty acids in hyperphenylalaninemia. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11237478 |
| Thies F et al. | Dietary supplementation with eicosapentaenoic acid, but not with other long-chain n-3 or n-6 polyunsaturated fatty acids, decreases natural killer cell activity in healthy subjects aged >55 y. | 2001 | Am. J. Clin. Nutr. | pmid:11237929 |
| Menéndez JA et al. | Effects of gamma-linolenic acid and oleic acid on paclitaxel cytotoxicity in human breast cancer cells. | 2001 | Eur. J. Cancer | pmid:11239764 |
| Kankaanpää PE et al. | The influence of polyunsaturated fatty acids on probiotic growth and adhesion. | 2001 | FEMS Microbiol. Lett. | pmid:11164299 |
| Ito Y et al. | Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. | 2001 | Cancer Lett. | pmid:11165751 |
| Reinikainen M et al. | The toxicities of a polyunsaturated fatty acid and a microcystin to Daphnia magna. | 2001 | Environ. Toxicol. | pmid:11594032 |
| Ide T et al. | Dietary mold oil rich in gamma linolenic acid increases insulin-dependent glucose utilization in isolated rat adipocytes. | 2001 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:11567903 |
| Kaku S et al. | Dietary gamma-linolenic acid dose-dependently modifies fatty acid composition and immune parameters in rats. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728173 |
| Colquhoun A and Schumacher RI | gamma-Linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells. | 2001 | Biochim. Biophys. Acta | pmid:11731331 |
| Birch AE et al. | Antioxidant properties of evening primrose seed extracts. | 2001 | J. Agric. Food Chem. | pmid:11559161 |
| Demmelmair H et al. | Influence of formulas with borage oil or borage oil plus fish oil on the arachidonic acid status in premature infants. | 2001 | Lipids | pmid:11485158 |
| Guil-Guerrero JL et al. | Occurrence and characterization of oils rich in gamma-linolenic acid (III): the taxonomical value of the fatty acids in Echium (Boraginaceae). | 2001 | Phytochemistry | pmid:11524120 |
| Ford I et al. | The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat. | 2001 | Metab. Clin. Exp. | pmid:11474472 |
| Tsimaratos M et al. | Gamma-linolenic acid restores renal medullary thick ascending limb Na(+),K(+)-ATPase activity in diabetic rats. | 2001 | J. Nutr. | pmid:11739860 |
| Thies F et al. | Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. | 2001 | Lipids | pmid:11795850 |
| Kaku S et al. | Interactions of dietary fats and proteins on fatty acid composition of immune cells and LTB4 production by peritoneal exudate cells of rats. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11302164 |
| Sims EC and Plowman PN | Stereotactic radiosurgery XII. Large AVM and the failure of the radiation response modifier gamma linolenic acid to improve the therapeutic ratio. | 2001 | Br J Neurosurg | pmid:11303657 |
| Little C and Parsons T | Herbal therapy for treating rheumatoid arthritis. | 2001 | Cochrane Database Syst Rev | pmid:11279784 |
| Fauconnot L and Buist PH | Gamma-linolenic acid biosynthesis: cryptoregiochemistry of delta6 desaturation. | 2001 | J. Org. Chem. | pmid:11312950 |
| Kenny FS et al. | Effect of dietary GLA+/-tamoxifen on the growth, ER expression and fatty acid profile of ER positive human breast cancer xenografts. | 2001 | Int. J. Cancer | pmid:11291069 |
| Colquhoun A and Schumacher RI | Modifications in mitochondrial metabolism and ultrastructure and their relationship to tumour growth inhibition by gamma-linolenic acid. | 2001 | Mol. Cell. Biochem. | pmid:11330827 |
| Hrelia S et al. | Role of gamma-linolenic acid in counteracting doxorubicin-induced damage in cultured rat cardiomyocytes. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11334548 |
| Barre DE | Potential of evening primrose, borage, black currant, and fungal oils in human health. | 2001 | Ann. Nutr. Metab. | pmid:11359029 |
| Kankaanpää P et al. | Polyunsaturated fatty acids in maternal diet, breast milk, and serum lipid fatty acids of infants in relation to atopy. | 2001 | Allergy | pmid:11421921 |
| Mainou-Fowler T et al. | Gamma-linolenic acid induces apoptosis in B-chronic lymphocytic leukaemia cells in vitro. | 2001 | Leuk. Lymphoma | pmid:11426562 |
| Serrano I et al. | Ethanol-induced dimorphism and lipid composition changes in Mucor fragilis CCMI 142. | 2001 | Lett. Appl. Microbiol. | pmid:11442823 |
| Hou X et al. | 2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite. | 2001 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:11448840 |
| Furse RK et al. | Gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, blocks amplification of IL-1 beta production by human monocytes. | 2001 | J. Immunol. | pmid:11418687 |
| Thies F et al. | Dietary supplementation with gamma-linolenic acid or fish oil decreases T lymphocyte proliferation in healthy older humans. | 2001 | J. Nutr. | pmid:11435508 |
| Yogo Y and Fujishima S | [Nutritional support for ARDS]. | 2001 | Nippon Rinsho | pmid:11439576 |
| Frenoux JM et al. | A polyunsaturated fatty acid diet lowers blood pressure and improves antioxidant status in spontaneously hypertensive rats. | 2001 | J. Nutr. | pmid:11208936 |
| Chan LW et al. | Microencapsulation of oils using sodium alginate. | 2000 Nov-Dec | J Microencapsul | pmid:11063422 |
| Belch JJ and Hill A | Evening primrose oil and borage oil in rheumatologic conditions. | 2000 | Am. J. Clin. Nutr. | pmid:10617996 |
| Head RJ et al. | Prevention of nerve conduction deficit in diabetic rats by polyunsaturated fatty acids. | 2000 | Am. J. Clin. Nutr. | pmid:10618002 |
| Schwartz J | Role of polyunsaturated fatty acids in lung disease. | 2000 | Am. J. Clin. Nutr. | pmid:10618003 |
| Burke A et al. | Specific analysis in plasma and urine of 2,3-dinor-5, 6-dihydro-isoprostane F(2alpha)-III, a metabolite of isoprostane F(2alpha)-III and an oxidation product of gamma-linolenic acid. | 2000 | J. Biol. Chem. | pmid:10644705 |
| Peth JA et al. | Effects of a unique conjugate of alpha-lipoic acid and gamma-linolenic acid on insulin action in obese Zucker rats. | 2000 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:10666147 |
| Jiang WG et al. | Peroxisome proliferator activated receptor-gamma (PPAR-gamma) mediates the action of gamma linolenic acid in breast cancer cells. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780877 |
| Leonard AE et al. | cDNA cloning and characterization of human Delta5-desaturase involved in the biosynthesis of arachidonic acid. | 2000 | Biochem. J. | pmid:10769175 |
| Preuss M et al. | Role of antioxidant enzyme expression in the selective cytotoxic response of glioma cells to gamma-linolenic acid supplementation. | 2000 | Free Radic. Biol. Med. | pmid:10832077 |
| Palombo JD et al. | Comparison of growth and fatty acid metabolism in rats fed diets containing equal levels of gamma-linolenic acid from high gamma-linolenic acid canola oil or borage oil. | 2000 | Lipids | pmid:11026618 |
| Fokkema MR et al. | Short-term supplementation of low-dose gamma-linolenic acid (GLA), alpha-linolenic acid (ALA), or GLA plus ALA does not augment LCP omega 3 status of Dutch vegans to an appreciable extent. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11090255 |
| Worm M and Henz BM | Novel unconventional therapeutic approaches to atopic eczema. | 2000 | Dermatology (Basel) | pmid:11096188 |
| Harbige LS et al. | The protective effects of omega-6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-beta1) up-regulation and increased prostaglandin E2 (PGE2) production. | 2000 | Clin. Exp. Immunol. | pmid:11122253 |
| Horner NK and Lampe JW | Potential mechanisms of diet therapy for fibrocystic breast conditions show inadequate evidence of effectiveness. | 2000 | J Am Diet Assoc | pmid:11103660 |
| Pakala R et al. | Vascular smooth muscle cells preloaded with eicosapentaenoic acid and docosahexaenoic acid fail to respond to serotonin stimulation. | 2000 | Atherosclerosis | pmid:11058699 |
| Vinik AI et al. | Diabetic neuropathies. | 2000 | Diabetologia | pmid:10990072 |
| Iijima S et al. | Oral supplementation with gamma-linolenic acid extracted from Mucor circinelloides improves the deformability of red blood cells in hemodialysis patients. | 2000 | Nephron | pmid:11014980 |
| Arnold LE et al. | Does zinc moderate essential fatty acid and amphetamine treatment of attention-deficit/hyperactivity disorder? | 2000 | J Child Adolesc Psychopharmacol | pmid:10933121 |
| Guil-Guerrero JL et al. | Occurrence and characterization of oils rich in gamma-linolenic acid part II: fatty acids and squalene from Macaronesian Echium leaves. | 2000 | Phytochemistry | pmid:10939357 |
| Liu QY and Tan BK | Effects of cis-unsaturated fatty acids on doxorubicin sensitivity in P388/DOX resistant and P388 parental cell lines. | 2000 | Life Sci. | pmid:10954054 |
| Parker-Barnes JM et al. | Identification and characterization of an enzyme involved in the elongation of n-6 and n-3 polyunsaturated fatty acids. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10899997 |
| Rahbeeni F et al. | The effect of evening primrose oil on the radiation response and blood flow of mouse normal and tumour tissue. | 2000 | Int. J. Radiat. Biol. | pmid:10902742 |
| Kapoor R and Klimaszewski A | Efficacy of borage oil in patients with atopic eczema. | 2000 | Br. J. Dermatol. | pmid:10886164 |
| Simán CM et al. | Failure of short-term gamma-linolenic acid treatment to reduce urinary calcium loss of diabetic rats. | 2000 | Urol. Res. | pmid:10850637 |
| Murray MJ et al. | Effects of eicosapentaenoic and gamma-linolenic acids (dietary lipids) on pulmonary surfactant composition and function during porcine endotoxemia. | 2000 | Chest | pmid:10858408 |
| Oguogho A et al. | Prostaglandin synthesis in human lymphatics from precursor fatty acids. | 2000 | Lymphology | pmid:10897472 |
| Barham JB et al. | Addition of eicosapentaenoic acid to gamma-linolenic acid-supplemented diets prevents serum arachidonic acid accumulation in humans. | 2000 | J. Nutr. | pmid:10917903 |
| Kenny FS et al. | Gamma linolenic acid with tamoxifen as primary therapy in breast cancer. | 2000 | Int. J. Cancer | pmid:10699943 |
| Ravichandran D et al. | Effect of 1-(gamma)linolenyl-3-eicosapentaenoyl propane diol on the growth of human pancreatic carcinoma in vitro and in vivo. | 2000 | Eur. J. Cancer | pmid:10708945 |
| Thijs C et al. | Essential fatty acids in breast milk of atopic mothers: comparison with non-atopic mothers, and effect of borage oil supplementation. | 2000 | Eur J Clin Nutr | pmid:10713746 |
| Guil-Guerrero JL et al. | Occurrence and characterization of oils rich in gamma-linolenic acid Part I: Echium seeds from Macaronesia. | 2000 | Phytochemistry | pmid:10731022 |
| Hindo J et al. | Evidence of the formation of different hydroperoxides in irradiated gamma-linolenate solutions: effect of micelle formation. | 2000 | Radiat. Res. | pmid:10629620 |
| Takahashi Y et al. | Dietary gamma-linolenic acid in the form of borage oil causes less body fat accumulation accompanying an increase in uncoupling protein 1 mRNA level in brown adipose tissue. | 2000 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:11079375 |
| Kumar KV et al. | Oxidant stress and essential fatty acids in patients with risk and established ARDS. | 2000 | Clin. Chim. Acta | pmid:10876008 |
| Dobson G | Leaf lipids of Ribes nigrum: a plant containing 16:3, alpha-18:3, gamma-18:3 and 18:4 fatty acids. | 2000 | Biochem. Soc. Trans. | pmid:11171133 |
| Beaudoin F et al. | Production of C20 polyunsaturated fatty acids (PUFAs) by pathway engineering: identification of a PUFA elongase component from Caenorhabditis elegans. | 2000 | Biochem. Soc. Trans. | pmid:11171161 |
| Shahidi F | Antioxidant factors in plant foods and selected oilseeds. | 2000 | Biofactors | pmid:11237180 |
| Horrobin DF | Essential fatty acid metabolism and its modification in atopic eczema. | 2000 | Am. J. Clin. Nutr. | pmid:10617999 |
| Charnock JS | Gamma-linolenic acid provides additional protection against ventricular fibrillation in aged rats fed linoleic acid rich diets. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10780878 |
| Cohen SM et al. | Therapeutic use of selected herbs. | 2000 | Holist Nurs Pract | pmid:12119629 |
| Mohan IK and Das UN | Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10765977 |
| Decsi T et al. | Effect of type of early infant feeding on fatty acid composition of plasma lipid classes in full-term infants during the second 6 months of life. | 2000 | J. Pediatr. Gastroenterol. Nutr. | pmid:10817286 |
| Petrik MB et al. | Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. | 2000 | J. Nutr. | pmid:11015469 |
| Dove D and Johnson P | Oral evening primrose oil: its effect on length of pregnancy and selected intrapartum outcomes in low-risk nulliparous women. | 1999 May-Jun | J Nurse Midwifery | pmid:10380450 |
| De Antueno R et al. | Tissue distribution and metabolism of gamma-linolenoyl-3-eicosapentaenoyl propane diol enterally or intravenously administered to mice bearing human pancreatic carcinomas. | 1999 May-Jun | Anticancer Res. | pmid:10470146 |
| Zurier RB et al. | Human peripheral blood T lymphocyte proliferation after activation of the T cell receptor: effects of unsaturated fatty acids. | 1999 May-Jun | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10471124 |
| Pakala R et al. | Eicosapentaenoic acid and docosahexaenoic acid selectively attenuate U46619-induced smooth muscle cell proliferation. | 1999 | Lipids | pmid:10574655 |
| Ward GR et al. | Effects of gamma-linolenic acid and docosahexaenoic acid in formulae on brain fatty acid composition in artificially reared rats. | 1999 | Lipids | pmid:10580333 |
| Joubert AM et al. | Comparative study of the effects of polyunsaturated fatty acids and their metabolites on cell growth and tyrosine kinase activity in oesophageal carcinoma cells. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10582657 |
| Wolf LA and Laster SM | Characterization of arachidonic acid-induced apoptosis. | 1999 | Cell Biochem. Biophys. | pmid:10403056 |
| Cai J et al. | Inhibition of the expression of VE-cadherin/catenin complex by gamma linolenic acid in human vascular endothelial cells, and its impact on angiogenesis. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10222244 |
| Leaver HA et al. | Dynamics of reactive oxygen intermediate production in human glioma: n-6 essential fatty acid effects. | 1999 | Eur. J. Clin. Invest. | pmid:10202379 |
| Senanayake SP and Shahidi F | Enzyme-assisted acidolysis of borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils: incorporation of omega-3 polyunsaturated fatty acids. | 1999 | J. Agric. Food Chem. | pmid:10552616 |
| Gehring W et al. | Effect of topically applied evening primrose oil on epidermal barrier function in atopic dermatitis as a function of vehicle. | 1999 | Arzneimittelforschung | pmid:10442214 |
| Cheung KL | Management of cyclical mastalgia in oriental women: pioneer experience of using gamolenic acid (Efamast) in Asia. | 1999 | Aust N Z J Surg | pmid:10442919 |
| De La Cruz JP et al. | Antioxidant potential of evening primrose oil administration in hyperlipemic rabbits. | 1999 | Life Sci. | pmid:10462081 |
| Schwartz Z et al. | Arachidonic acid directly mediates the rapid effects of 24,25-dihydroxyvitamin D3 via protein kinase C and indirectly through prostaglandin production in resting zone chondrocytes. | 1999 | Endocrinology | pmid:10385391 |
| Henz BM et al. | Double-blind, multicentre analysis of the efficacy of borage oil in patients with atopic eczema. | 1999 | Br. J. Dermatol. | pmid:10233322 |
| Likhodii SS and Cunnane SC | Uptake of 13C-tracer arachidonate and gamma-linolenate by the brain and liver of the suckling rat observed using 13C-NMR. | 1999 | J. Neurochem. | pmid:10349866 |