gamma-Linolenic acid

Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.

Cross Reference

Introduction

To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid

MeSH term MeSH ID Detail
Urolithiasis D052878 1 associated lipids
Fibrocystic Breast Disease D005348 1 associated lipids
Mucocele D009078 1 associated lipids
Salivary Gland Diseases D012466 1 associated lipids
Tietze's Syndrome D013991 1 associated lipids
Fallopian Tube Neoplasms D005185 1 associated lipids
Scurvy D012614 2 associated lipids
Carcinoma, Mucoepidermoid D018277 3 associated lipids
Arthritis, Psoriatic D015535 3 associated lipids
Mastocytoma D034801 3 associated lipids
Ecchymosis D004438 3 associated lipids
Pityriasis D010915 3 associated lipids
Carpal Tunnel Syndrome D002349 3 associated lipids
Gastritis, Atrophic D005757 4 associated lipids
Back Pain D001416 5 associated lipids
Hand Dermatoses D006229 5 associated lipids
Intermittent Claudication D007383 6 associated lipids
Xerostomia D014987 6 associated lipids
Premenstrual Syndrome D011293 7 associated lipids
Bacteriuria D001437 7 associated lipids
Kidney Calculi D007669 7 associated lipids
Raynaud Disease D011928 7 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Nausea D009325 7 associated lipids
Dysmenorrhea D004412 9 associated lipids
Ascorbic Acid Deficiency D001206 9 associated lipids
Respiratory Insufficiency D012131 10 associated lipids
Dermatitis, Seborrheic D012628 10 associated lipids
Fatigue D005221 10 associated lipids
Critical Illness D016638 13 associated lipids
Synovitis D013585 15 associated lipids
Respiratory Distress Syndrome, Adult D012128 15 associated lipids
Dyskinesia, Drug-Induced D004409 15 associated lipids
Scleroderma, Systemic D012595 16 associated lipids
Liver Cirrhosis, Alcoholic D008104 17 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Neoplasm Invasiveness D009361 23 associated lipids
Neoplasms, Hormone-Dependent D009376 23 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Gastritis D005756 27 associated lipids
Alcoholism D000437 27 associated lipids
Dermatitis D003872 30 associated lipids
Acute Lung Injury D055371 33 associated lipids
Hyperplasia D006965 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with gamma-Linolenic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with gamma-Linolenic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with gamma-Linolenic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with gamma-Linolenic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with gamma-Linolenic acid

Download all related citations
Per page 10 20 50 100 | Total 1121
Authors Title Published Journal PubMed Link
Stahl A et al. Identification of the major intestinal fatty acid transport protein. 1999 Mol. Cell pmid:10518211
Srinivas CV et al. Safflower petals: a source of gamma linolenic acid. 1999 Plant Foods Hum Nutr pmid:10646633
Hornych A et al. Effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandins in old subjects. 1999 Br J Clin Pharmacol pmid:10651470
Fan YY et al. Modulation of atherogenesis by dietary gamma-linolenic acid. 1999 Adv. Exp. Med. Biol. pmid:10667372
Vartak S et al. The selective cytotoxicity of gamma-linolenic acid (GLA) is associated with increased oxidative stress. 1999 Adv. Exp. Med. Biol. pmid:10667373
Robbins M et al. gamma-linolenic acid (GLA)-mediated cytotoxicity in human prostate cancer cells. 1999 Adv. Exp. Med. Biol. pmid:10667374
Harris JE et al. Five-lipoxygenase inhibitors reduce Panc-1 survival: synergism of MK886 with gamma linolenic acid. 1999 Adv. Exp. Med. Biol. pmid:10667375
Ramrath S et al. Stimulation of cardiac glucose transport by thioctic acid and insulin. 1999 Horm. Metab. Res. pmid:10668913
Motaung E et al. Cytotoxicity of combined essential fatty acids on a human prostate cancer cell line. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10670696
Davies CL et al. Effect of gamma-linolenic acid on cellular uptake of structurally related anthracyclines in human drug sensitive and multidrug resistant bladder and breast cancer cell lines. 1999 Eur. J. Cancer pmid:10673983
Cai J et al. Inhibition of angiogenic factor- and tumour-induced angiogenesis by gamma linolenic acid. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10319914
Ihara-Watanabe M et al. Effects of dietary alpha- or gamma-linolenic acid on levels and fatty acid compositions of serum and hepatic lipids, and activity and mRNA abundance of 3-hydroxy-3-methylglutaryl CoA reductase in rats. 1999 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:10327618
Giamarellos-Bourboulis EJ et al. In vitro interactions of gamma-linolenic acid and arachidonic acid with ceftazidime on multiresistant Pseudomonas aeruginosa. 1999 Lipids pmid:10419130
Hrelia S et al. Concentration- and time-dependent effects of gamma-linolenic acid supplementation to tumor cells in culture. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10397404
Pakala R et al. Thromboxane A2 fails to induce proliferation of smooth muscle cells enriched with eicosapentaenoic acid and docosahexaenoic acid. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10397410
Woltil HA et al. Does supplementation of formula with evening primrose and fish oils augment long chain polyunsaturated fatty acid status of low birthweight infants to that of breast-fed counterparts? 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10359022
DeLuca P et al. Effects of gammalinolenic acid on interleukin-1 beta and tumor necrosis factor-alpha secretion by stimulated human peripheral blood monocytes: studies in vitro and in vivo. 1999 J. Investig. Med. pmid:10361385
Ilc K et al. Cytotoxic effects of two gamma linoleic salts (lithium gammalinolenate or meglumine gammalinolenate) alone or associated with a nitrosourea: an experimental study on human glioblastoma cell lines. 1999 Anticancer Drugs pmid:10378677
Tsevegsüren N et al. Occurrence of gamma-linolenic acid in compositae: a study of Youngia tenuicaulis seed oil. 1999 Lipids pmid:10380126
Warren G et al. The role of essential fatty acids in chronic fatigue syndrome. A case-controlled study of red-cell membrane essential fatty acids (EFA) and a placebo-controlled treatment study with high dose of EFA. 1999 Acta Neurol. Scand. pmid:10071170
Muñoz SE et al. Differential effects of dietary Oenothera, Zizyphus mistol, and corn oils, and essential fatty acid deficiency on the progression of a murine mammary gland adenocarcinoma. 1999 Nutrition pmid:10198915
Tamimi NA et al. Role of gamma-linolenic acid in uraemic pruritus. 1999 Nephron pmid:10516500
Wu D et al. Effect of dietary supplementation with black currant seed oil on the immune response of healthy elderly subjects. 1999 Am. J. Clin. Nutr. pmid:10500023
Peterson LD et al. Dose-dependent effects of dietary gamma-linolenic acid on rat spleen lymphocyte functions. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10477037
Haag M et al. Polyunsaturated fatty acids inhibit Mg2+ -ATPase in basolateral membranes from rat enterocytes. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10477038
Huang YS et al. Cloning of delta12- and delta6-desaturases from Mortierella alpina and recombinant production of gamma-linolenic acid in Saccharomyces cerevisiae. 1999 Lipids pmid:10478922
Gadek JE et al. Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome. Enteral Nutrition in ARDS Study Group. 1999 Crit. Care Med. pmid:10470743
Passorn S et al. Heterologous expression of Mucor rouxii delta(12)-desaturase gene in Saccharomyces cerevisiae. 1999 Biochem. Biophys. Res. Commun. pmid:10486251
Patel J and Tomlinson DR Nerve conduction impairment in experimental diabetes-proximodistal gradient of severity. 1999 Muscle Nerve pmid:10487907
Palombo JD et al. Effect of short-term enteral feeding with eicosapentaenoic and gamma-linolenic acids on alveolar macrophage eicosanoid synthesis and bactericidal function in rats. 1999 Crit. Care Med. pmid:10507617
Yoshimoto-Furuie K et al. Effects of oral supplementation with evening primrose oil for six weeks on plasma essential fatty acids and uremic skin symptoms in hemodialysis patients. 1999 Nephron pmid:9933750
Khamaisi M et al. Metabolic effects of gamma-linolenic acid-alpha-lipoic acid conjugate in streptozotocin diabetic rats. 1999 Antioxid. Redox Signal. pmid:11233149
Pirich C et al. Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. 1999 Thromb. Res. pmid:10588465
Redden PR et al. Acyloxymethyl acidic drug derivatives: in vitro hydrolytic reactivity. 1999 Int J Pharm pmid:10370185
Dove D and Johnson P Oral evening primrose oil: its effect on length of pregnancy and selected intrapartum outcomes in low-risk nulliparous women. 1999 May-Jun J Nurse Midwifery pmid:10380450
De Antueno R et al. Tissue distribution and metabolism of gamma-linolenoyl-3-eicosapentaenoyl propane diol enterally or intravenously administered to mice bearing human pancreatic carcinomas. 1999 May-Jun Anticancer Res. pmid:10470146
Zurier RB et al. Human peripheral blood T lymphocyte proliferation after activation of the T cell receptor: effects of unsaturated fatty acids. 1999 May-Jun Prostaglandins Leukot. Essent. Fatty Acids pmid:10471124
Belch JJ and Hill A Evening primrose oil and borage oil in rheumatologic conditions. 2000 Am. J. Clin. Nutr. pmid:10617996
Head RJ et al. Prevention of nerve conduction deficit in diabetic rats by polyunsaturated fatty acids. 2000 Am. J. Clin. Nutr. pmid:10618002
Rahbeeni F et al. The effect of evening primrose oil on the radiation response and blood flow of mouse normal and tumour tissue. 2000 Int. J. Radiat. Biol. pmid:10902742
Kapoor R and Klimaszewski A Efficacy of borage oil in patients with atopic eczema. 2000 Br. J. Dermatol. pmid:10886164
Simán CM et al. Failure of short-term gamma-linolenic acid treatment to reduce urinary calcium loss of diabetic rats. 2000 Urol. Res. pmid:10850637
Murray MJ et al. Effects of eicosapentaenoic and gamma-linolenic acids (dietary lipids) on pulmonary surfactant composition and function during porcine endotoxemia. 2000 Chest pmid:10858408
Oguogho A et al. Prostaglandin synthesis in human lymphatics from precursor fatty acids. 2000 Lymphology pmid:10897472
Barham JB et al. Addition of eicosapentaenoic acid to gamma-linolenic acid-supplemented diets prevents serum arachidonic acid accumulation in humans. 2000 J. Nutr. pmid:10917903
Kenny FS et al. Gamma linolenic acid with tamoxifen as primary therapy in breast cancer. 2000 Int. J. Cancer pmid:10699943
Ravichandran D et al. Effect of 1-(gamma)linolenyl-3-eicosapentaenoyl propane diol on the growth of human pancreatic carcinoma in vitro and in vivo. 2000 Eur. J. Cancer pmid:10708945
Thijs C et al. Essential fatty acids in breast milk of atopic mothers: comparison with non-atopic mothers, and effect of borage oil supplementation. 2000 Eur J Clin Nutr pmid:10713746
Takahashi Y et al. Dietary gamma-linolenic acid in the form of borage oil causes less body fat accumulation accompanying an increase in uncoupling protein 1 mRNA level in brown adipose tissue. 2000 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:11079375
Cohen SM et al. Therapeutic use of selected herbs. 2000 Holist Nurs Pract pmid:12119629