Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Luthria DL and Sprecher H | Metabolism of deuterium-labeled linoleic, 6,9,12-octadecatrienoic, 8,11,14-eicosatrienoic, and arachidonic acids in the rat. | 1995 | J. Lipid Res. | pmid:8558078 |
Morris GM et al. | Trophic effects of essential fatty acids on pig skin. | 1995 | Cell Prolif. | pmid:7893841 |
Murai A et al. | Role of dietary gamma-linolenic acid in liver lipid metabolism in Japanese quail. | 1995 | Br. Poult. Sci. | pmid:8746984 |
Bell JG et al. | Diets rich in eicosapentaenoic acid and gamma-linolenic acid affect phospholipid fatty acid composition and production of prostaglandins E1, E2 and E3 in turbot (Scophthalmus maximus), a species deficient in delta 5 fatty acid desaturase. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8577782 |
Rothman D et al. | Botanical lipids: effects on inflammation, immune responses, and rheumatoid arthritis. | 1995 | Semin. Arthritis Rheum. | pmid:8578315 |
Koba K et al. | Distribution of plasma phosphatidylcholine molecular species in rabbits fed fish oil is modulated by dietary n-6 fatty acids. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8821127 |
Leichsenring M et al. | (n-6)-Fatty acids in plasma lipids of children with atopic bronchial asthma. | 1995 | Pediatr Allergy Immunol | pmid:8822394 |
Cartwright-Shamoon JM et al. | A complex biochemical modulation of intestinal ion transport in rats fed on high-fat diets. | 1995 | J. Pediatr. Gastroenterol. Nutr. | pmid:7884616 |
Karikó K et al. | Stimulatory effect of unsaturated fatty acids on the level of plasminogen activator inhibitor-1 mRNA in cultured human endothelial cells. | 1995 | FEBS Lett. | pmid:7890029 |
Lindskov R and Petersen CS | [Oral gamma-linoleic acid (Epogam) in the treatment of atopic dermatitis]. | 1995 | Ugeskr. Laeg. | pmid:7483071 |
Hrelia S et al. | Essential fatty acid metabolism in cultured rat cardiomyocytes in response to either N-6 or N-3 fatty acid supplementation. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7488075 |
Chajès V et al. | Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: relationship to peroxides and vitamin-E. | 1995 | Breast Cancer Res. Treat. | pmid:7579484 |
Larsson-Backström C et al. | Effects of dietary alpha- and gamma-linolenic acids on liver fatty acids, lipid metabolism, and survival in sepsis. | 1995 | Shock | pmid:7552772 |
Das UN et al. | Local application of gamma-linolenic acid in the treatment of human gliomas. | 1995 | Cancer Lett. | pmid:7634242 |
Jiang WG et al. | Inhibition of hepatocyte growth factor-induced motility and in vitro invasion of human colon cancer cells by gamma-linolenic acid. | 1995 | Br. J. Cancer | pmid:7710939 |
Jiang WG et al. | Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA). | 1995 | Cancer Res. | pmid:7585549 |
Schoemaker JH | Pharmacological treatment of diabetic peripheral neuropathy: challenges and possibilities. | 1994 Mar-Apr | Br J Clin Pract | pmid:8024999 |
Hauben M | Comment: evening primrose oil in the treatment of rheumatoid arthritis--proper application of statistical analysis. | 1994 Jul-Aug | Ann Pharmacother | pmid:7832860 |
Fiocchi A et al. | The efficacy and safety of gamma-linolenic acid in the treatment of infantile atopic dermatitis. | 1994 Jan-Feb | J. Int. Med. Res. | pmid:7910570 |
Falconer JS et al. | Polyunsaturated fatty acids in the treatment of weight-losing patients with pancreatic cancer. | 1994 | World Rev Nutr Diet | pmid:7856240 |
BeLieu RM | Mastodynia. | 1994 | Obstet. Gynecol. Clin. North Am. | pmid:7816407 |
Berth-Jones J and Graham-Brown RA | Evening primrose oil. Does not show promise in atopic dermatitis. | 1994 | BMJ | pmid:7819863 |
Rubin M et al. | Effect of three intravenously administered fat emulsions containing different concentrations of fatty acids on the plasma fatty acid composition of premature infants. | 1994 | J. Pediatr. | pmid:7931881 |
Miller MA and Morgan RJ | Eicosanoids, erections and erectile dysfunction. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7938091 |
Darlington LG and Ramsey NW | Review of dietary therapy for rheumatoid arthritis. | 1994 | Compr Ther | pmid:7805365 |
Guivernau M et al. | Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7846101 |
Hopewell JW et al. | Amelioration of both early and late radiation-induced damage to pig skin by essential fatty acids. | 1994 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:7961020 |
McCaul JA and Lamey PJ | Multiple oral mucoceles treated with gamma-linolenic acid: report of a case. | 1994 | Br J Oral Maxillofac Surg | pmid:7849001 |
Christophe A et al. | Effect of administration of gamma-linolenic acid on the fatty acid composition of serum phospholipids and cholesteryl esters in patients with cystic fibrosis. | 1994 | Ann. Nutr. Metab. | pmid:8185286 |
du Toit PJ et al. | Pyelonephritis: renal urokinase activity in rats on essential fatty acid diets. | 1994 | Urol. Res. | pmid:7992455 |
de Kock M et al. | Differential cytotoxic effects of gamma-linolenic acid on MG-63 and HeLa cells. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7972263 |
du Toit PJ et al. | The effect of gamma-linolenic acid and eicosapentaenoic acid on urokinase activity. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:7972265 |
Milner LS et al. | Synergistic effects of fish oil diet and dimethylthiourea in acute adriamycin nephrosis. | 1994 | Am. J. Med. Sci. | pmid:7977444 |
Bond R and Lloyd DH | Combined treatment with concentrated essential fatty acids and prednisolone in the management of canine atopy. | 1994 | Vet. Rec. | pmid:8135003 |
Phinney S | Potential risk of prolonged gamma-linolenic acid use. | 1994 | Ann. Intern. Med. | pmid:8135457 |
Chenoy R et al. | Effect of oral gamolenic acid from evening primrose oil on menopausal flushing. | 1994 | BMJ | pmid:8136666 |
Giamarellos-Bourboulis EJ et al. | Do Escherichia coli susceptibilities to various antibiotics decrease in the presence of polyunsaturated fatty acids? A preliminary report. | 1994 | J Chemother | pmid:8071677 |
Kirchgessner M et al. | The effects of dietary oils on the fatty acid composition and osmotic fragility of rat erythrocytes. | 1994 | Z Ernahrungswiss | pmid:8079509 |
Leventhal LJ et al. | Treatment of rheumatoid arthritis with blackcurrant seed oil. | 1994 | Br. J. Rheumatol. | pmid:8081671 |
Takada R et al. | Dietary gamma-linolenic acid-enriched oil reduces body fat content and induces liver enzyme activities relating to fatty acid beta-oxidation in rats. | 1994 | J. Nutr. | pmid:8145067 |
Morphake P et al. | Alteration of cyclosporine (CsA)-induced nephrotoxicity by gamma linolenic acid (GLA) and eicosapentaenoic acid (EPA) in Wistar rats. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8146206 |
Devi MA and Das NP | Antiproliferative effect of polyunsaturated fatty acids and interleukin-2 on normal and abnormal human lymphocytes. | 1994 | Experientia | pmid:8194587 |
Jamal GA | The use of gamma linolenic acid in the prevention and treatment of diabetic neuropathy. | 1994 | Diabet. Med. | pmid:8200197 |
Ramanathan R et al. | Effects of gamma-linolenic acid, flavonoids, and vitamins on cytotoxicity and lipid peroxidation. | 1994 | Free Radic. Biol. Med. | pmid:8299995 |
Maaswinkel-Mooij PD et al. | Unsuccessful dietary treatment of Sjögren-Larsson syndrome. | 1994 | J. Pediatr. | pmid:8176565 |
Wetzig NR | Mastalgia: a 3 year Australian study. | 1994 | Aust N Z J Surg | pmid:8179529 |
Tate GA and Zurier RB | Suppression of monosodium urate crystal-induced inflammation by black currant seed oil. | 1994 | Agents Actions | pmid:7741038 |
Goldfien A | Premenstrual syndrome. | 1994 | Curr Ther Endocrinol Metab | pmid:7704719 |
Biagi PL et al. | The effect of gamma-linolenic acid on clinical status, red cell fatty acid composition and membrane microviscosity in infants with atopic dermatitis. | 1994 | Drugs Exp Clin Res | pmid:7924900 |
Cameron NE and Cotter MA | Effects of evening primrose oil treatment on sciatic nerve blood flow and endoneurial oxygen tension in streptozotocin-diabetic rats. | 1994 | Acta Diabetol | pmid:7888693 |