Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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SimoncÃkova P et al. | Comparison of the extrapancreatic action of gamma-linolenic acid and n-3 PUFAs in the high fat diet-induced insulin resistance [corrected]. | 2002 | Endocr Regul | pmid:12466014 |
Leaver HA et al. | Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12445487 |
Blommers J et al. | Evening primrose oil and fish oil for severe chronic mastalgia: a randomized, double-blind, controlled trial. | 2002 | Am. J. Obstet. Gynecol. | pmid:12439536 |
Senanayake SP and Shahidi F | Positional distribution of FA in TAG of enzymatically modified borage and evening primrose oils. | 2002 | Lipids | pmid:12371752 |
Turon F et al. | A direct method for regiospecific analysis of TAG using alpha-MAG. | 2002 | Lipids | pmid:12371754 |
Senanayake SP and Shahidi F | Structured lipids via lipase-catalyzed incorporation of eicosapentaenoic acid into borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils. | 2002 | J. Agric. Food Chem. | pmid:11804516 |
Braddock R et al. | gamma-Linoleic acid and ascorbic acid ameliorate the effects of experimental diabetes on electrolyte and bone homeostasis in pregnant rats. | 2002 | J. Endocrinol. | pmid:12010635 |
Crook TJ et al. | The effects of meglumine gamma linolenic acid (MeGLA) on an organ culture model of superficial bladder cancer. | 2002 | Urol. Res. | pmid:11942327 |
GarcÃa-Maroto F et al. | Cloning and molecular characterization of the delta6-desaturase from two echium plant species: production of GLA by heterologous expression in yeast and tobacco. | 2002 | Lipids | pmid:12030323 |
Colquhoun A | Gamma-linolenic acid alters the composition of mitochondrial membrane subfractions, decreases outer mitochondrial membrane binding of hexokinase and alters carnitine palmitoyltransferase I properties in the Walker 256 rat tumour. | 2002 | Biochim. Biophys. Acta | pmid:12069851 |
Menéndez JA et al. | Synergistic interaction between vinorelbine and gamma-linolenic acid in breast cancer cells. | 2002 | Breast Cancer Res. Treat. | pmid:12058962 |
Cook D et al. | Modification of fatty acid composition in tomato (Lycopersicon esculentum) by expression of a borage delta6-desaturase. | 2002 | Mol. Biotechnol. | pmid:12059112 |
Leaver HA et al. | Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma. | 2002 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12051954 |
Chung S et al. | Gamma-linolenic acid in borage oil reverses epidermal hyperproliferation in guinea pigs. | 2002 | J. Nutr. | pmid:12368400 |
Gillis RC et al. | Eicosapentaenoic acid and gamma-linolenic acid induce apoptosis in HL-60 cells. | 2002 | J. Surg. Res. | pmid:12384078 |
Pérez Y et al. | Measurement by nuclear magnetic resonance diffusion of the dimensions of the mobile lipid compartment in C6 cells. | 2002 | Cancer Res. | pmid:12384523 |
Ernst E | Ayurvedic medicines. | 2002 | Pharmacoepidemiol Drug Saf | pmid:12426929 |
Uesaka Y | [Prevention and treatment of diabetic neuropathy]. | 2002 | Nippon Rinsho | pmid:12430238 |
Das UN | Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. | 2002 | Nutrition | pmid:12297217 |
Samuels R et al. | Hypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndrome. | 2002 | J Med Food | pmid:12487756 |
Yoon S et al. | The therapeutic effect of evening primrose oil in atopic dermatitis patients with dry scaly skin lesions is associated with the normalization of serum gamma-interferon levels. | 2002 Jan-Feb | Skin Pharmacol. Appl. Skin Physiol. | pmid:11803254 |
Das UN | Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. | 2002 Jul-Aug | Nutrition | pmid:12093450 |
Funtikova NS et al. | [Synthesis of biologically active lipids by fungus Mucor lusitanicus 306D grown on media with various composition]. | 2002 Nov-Dec | Prikl. Biokhim. Mikrobiol. | pmid:12449793 |
Delmonte P et al. | Synthesis and isolation of trans-7,cis-9 octadecadienoic acid and other CLA isomers by base conjugation of partially hydrogenated gamma-linolenic acid. | 2003 | Lipids | pmid:12880116 |
Surette ME et al. | Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects. | 2003 | Clin Ther | pmid:12852710 |
Surette ME et al. | Inhibition of leukotriene biosynthesis by a novel dietary fatty acid formulation in patients with atopic asthma: a randomized, placebo-controlled, parallel-group, prospective trial. | 2003 | Clin Ther | pmid:12852711 |
Whitehouse PA et al. | Synergistic activity of gamma-linolenic acid and cytotoxic drugs against pancreatic adenocarcinoma cell lines. | 2003 | Pancreatology | pmid:14526145 |
Song C et al. | Effects of dietary n-3 or n-6 fatty acids on interleukin-1beta-induced anxiety, stress, and inflammatory responses in rats. | 2003 | J. Lipid Res. | pmid:12837849 |
Vogelzang JL | Fat facts and fallacies. | 2003 | Home Healthc Nurse | pmid:14614382 |
Koletzko B et al. | Fatty acid profiles, antioxidant status, and growth of preterm infants fed diets without or with long-chain polyunsaturated fatty acids. A randomized clinical trial. | 2003 | Eur J Nutr | pmid:14569405 |
Arimura T et al. | Caspase-independent apoptosis induced by evening primrose extract in Ehrlich ascites tumor cells. | 2003 | Cancer Lett. | pmid:14580681 |
Barabino S et al. | Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. | 2003 | Cornea | pmid:12605039 |
Djoussé L et al. | Dietary linolenic acid is inversely associated with plasma triacylglycerol: the National Heart, Lung, and Blood Institute Family Heart Study. | 2003 | Am. J. Clin. Nutr. | pmid:14668270 |
Williams HC | Evening primrose oil for atopic dermatitis. | 2003 | BMJ | pmid:14670851 |
Takwale A et al. | Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. | 2003 | BMJ | pmid:14670885 |
Macrì A et al. | Effect of linoleic acid and gamma-linolenic acid on tear production, tear clearance and on the ocular surface after photorefractive keratectomy. | 2003 | Graefes Arch. Clin. Exp. Ophthalmol. | pmid:12768289 |
Jelińska M et al. | Effects of dietary linseed, evening primrose or fish oils on fatty acid and prostaglandin E2 contents in the rat livers and 7,12-dimethylbenz[a]anthracene-induced tumours. | 2003 | Biochim. Biophys. Acta | pmid:12697300 |
van Gool CJ et al. | Gamma-linolenic acid supplementation for prophylaxis of atopic dermatitis--a randomized controlled trial in infants at high familial risk. | 2003 | Am. J. Clin. Nutr. | pmid:12663296 |
Spector SL and Surette ME | Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma? | 2003 | Ann. Allergy Asthma Immunol. | pmid:12722956 |
Vecera R et al. | Antioxidant status, lipoprotein profile and liver lipids in rats fed on high-cholesterol diet containing currant oil rich in n-3 and n-6 polyunsaturated fatty acids. | 2003 | Physiol Res | pmid:12678660 |
Seibel MM | Treating hot flushes without hormone replacement therapy. | 2003 | J Fam Pract | pmid:12681090 |
Wainwright PE et al. | Effects of high-gamma-linolenic acid canola oil compared with borage oil on reproduction, growth, and brain and behavioral development in mice. | 2003 | Lipids | pmid:12733750 |
Soeken KL et al. | Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. | 2003 | Rheumatology (Oxford) | pmid:12709541 |
Duttaroy AK et al. | Acyl-CoA thioesterase activity in human placental choriocarcinoma (BeWo), cells: effects of fatty acids. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12538089 |
Pacht ER et al. | Enteral nutrition with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome. | 2003 | Crit. Care Med. | pmid:12576957 |
Xian M et al. | Production of gamma-linolenic acid by disrupted mycelia of Mortierella isabellina. | 2003 | Lett. Appl. Microbiol. | pmid:12581380 |
Rosenstein ED et al. | Pilot study of dietary fatty acid supplementation in the treatment of adult periodontitis. | 2003 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:12591005 |
Usami M et al. | Effect of gamma-linolenic acid or docosahexaenoic acid on tight junction permeability in intestinal monolayer cells and their mechanism by protein kinase C activation and/or eicosanoid formation. | 2003 | Nutrition | pmid:12591548 |
Hirano A et al. | Arachidonic acid-induced channel- and carrier-type ion transport across planar bilayer lipid membranes. | 2003 | Anal Sci | pmid:12608744 |
Shimizu S and Nakano M | Structural characterization of triacylglycerol in several oils containing gamma-linolenic acid. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12619674 |