Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hopewell JW et al. | Amelioration of both early and late radiation-induced damage to pig skin by essential fatty acids. | 1994 | Int. J. Radiat. Oncol. Biol. Phys. | pmid:7961020 |
Giamarellos-Bourboulis EJ et al. | Do Escherichia coli susceptibilities to various antibiotics decrease in the presence of polyunsaturated fatty acids? A preliminary report. | 1994 | J Chemother | pmid:8071677 |
Kirchgessner M et al. | The effects of dietary oils on the fatty acid composition and osmotic fragility of rat erythrocytes. | 1994 | Z Ernahrungswiss | pmid:8079509 |
Leventhal LJ et al. | Treatment of rheumatoid arthritis with blackcurrant seed oil. | 1994 | Br. J. Rheumatol. | pmid:8081671 |
Takada R et al. | Dietary gamma-linolenic acid-enriched oil reduces body fat content and induces liver enzyme activities relating to fatty acid beta-oxidation in rats. | 1994 | J. Nutr. | pmid:8145067 |
Morphake P et al. | Alteration of cyclosporine (CsA)-induced nephrotoxicity by gamma linolenic acid (GLA) and eicosapentaenoic acid (EPA) in Wistar rats. | 1994 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8146206 |
González CA et al. | Borage consumption as a possible gastric cancer protective factor. | 1993 Mar-Apr | Cancer Epidemiol. Biomarkers Prev. | pmid:8385521 |
Takeda S et al. | Mechanism of lipid peroxidation in cancer cells in response to gamma-linolenic acid (GLA) analyzed by GC-MS(I): Conjugated dienes with peroxyl (or hydroperoxyl) groups and cell-killing effects. | 1993 Jan-Feb | Anticancer Res. | pmid:8386494 |
Dehaut F et al. | n-6 polyunsaturated fatty acids increase the neurite length of PC12 cells and embryonic chick motoneurons. | 1993 | Neurosci. Lett. | pmid:8272254 |
Araya J and Cagalj A | [Exclusion of alpha-linolenic acid from diets for rats during several generations. I. Effect on reproduction and postnatal growth]. | 1993 | Arch Latinoam Nutr | pmid:7826185 |
Tollesson A and Frithz A | Transepidermal water loss and water content in the stratum corneum in infantile seborrhoeic dermatitis. | 1993 | Acta Derm. Venereol. | pmid:8095744 |
Berth-Jones J and Graham-Brown RA | Placebo-controlled trial of essential fatty acid supplementation in atopic dermatitis. | 1993 | Lancet | pmid:8099640 |
Shield MJ et al. | Essential fatty acid supplementation in atopic dermatitis. | 1993 | Lancet | pmid:8101623 |
Dines KC et al. | Contrasting effects of treatment with omega-3 and omega-6 essential fatty acids on peripheral nerve function and capillarization in streptozotocin-diabetic rats. | 1993 | Diabetologia | pmid:8270127 |
Szczesna M | [Therapeutic assessment of the evening primrose]. | 1993 | Rocz Panstw Zakl Hig | pmid:8016534 |
Laivuori H et al. | Dietary supplementation with primrose oil or fish oil does not change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8248275 |
Stevens EJ et al. | Prostacyclin release in experimental diabetes: effects of evening primrose oil. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8248277 |
Leyton E | Disagreeing on how to treat CFS patients. | 1993 | Can Fam Physician | pmid:8347205 |
Leventhal LJ et al. | Treatment of rheumatoid arthritis with gammalinolenic acid. | 1993 | Ann. Intern. Med. | pmid:8214997 |
Karlstad MD et al. | Effect of intravenous lipid emulsions enriched with gamma-linolenic acid on plasma n-6 fatty acids and prostaglandin biosynthesis after burn and endotoxin injury in rats. | 1993 | Crit. Care Med. | pmid:8222692 |
Harvey RG | Effect of varying proportions of evening primrose oil and fish oil on cats with crusting dermatosis ('miliary dermatitis') | 1993 | Vet. Rec. | pmid:8280288 |
Engler MM | Comparative study of diets enriched with evening primrose, black currant, borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8259378 |
Harvey RG | A comparison of evening primrose oil and sunflower oil for the management of papulocrustous dermatitis in cats. | 1993 | Vet. Rec. | pmid:8303807 |
Stevens EJ et al. | Essential fatty acid treatment prevents nerve ischaemia and associated conduction anomalies in rats with experimental diabetes mellitus. | 1993 | Diabetologia | pmid:8314443 |
Joe LA and Hart LL | Evening primrose oil in rheumatoid arthritis. | 1993 | Ann Pharmacother | pmid:8305783 |
Keen H et al. | Treatment of diabetic neuropathy with gamma-linolenic acid. The gamma-Linolenic Acid Multicenter Trial Group. | 1993 | Diabetes Care | pmid:8380765 |
Horrobin DF | The effects of gamma-linolenic acid on breast pain and diabetic neuropathy: possible non-eicosanoid mechanisms. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8380930 |
Hopewell JW et al. | The modulation of radiation-induced damage to pig skin by essential fatty acids. | 1993 | Br. J. Cancer | pmid:8391301 |
Cerin A et al. | Hormonal and biochemical profiles of premenstrual syndrome. Treatment with essential fatty acids. | 1993 | Acta Obstet Gynecol Scand | pmid:8392261 |
Galle AM et al. | Biosynthesis of gamma-linolenic acid in developing seeds of borage (Borago officinalis L.). | 1993 | Biochim. Biophys. Acta | pmid:8394742 |
Kinchington D et al. | Lithium gamma-linolenate-induced cytotoxicity against cells chronically infected with HIV-1. | 1993 | FEBS Lett. | pmid:8396048 |
Tollesson A and Frithz A | Borage oil, an effective new treatment for infantile seborrhoeic dermatitis. | 1993 | Br. J. Dermatol. | pmid:8396411 |
Cameron NE et al. | The effects of evening primrose oil on nerve function and capillarization in streptozotocin-diabetic rats: modulation by the cyclo-oxygenase inhibitor flurbiprofen. | 1993 | Br. J. Pharmacol. | pmid:8401950 |
Phinney SD et al. | Abnormal polyunsaturated lipid metabolism in the obese Zucker rat, with partial metabolic correction by gamma-linolenic acid administration. | 1993 | Metab. Clin. Exp. | pmid:8412765 |
Collins A et al. | Essential fatty acids in the treatment of premenstrual syndrome. | 1993 | Obstet Gynecol | pmid:8416468 |
Plumb JA et al. | Effect of polyunsaturated fatty acids on the drug sensitivity of human tumour cell lines resistant to either cisplatin or doxorubicin. | 1993 | Br. J. Cancer | pmid:8385976 |
Miura Y et al. | Production of gamma-linolenic acid from the marine green alga Chlorella sp. NKG 042401. | 1993 | FEMS Microbiol. Lett. | pmid:8386122 |
Karmali RA et al. | Plant and marine n-3 fatty acids inhibit experimental metastasis of rat mammary adenocarcinoma cells. | 1993 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8388566 |
Bala KV et al. | Inhibition of methyl mercury chloride-induced chromosomal damage by gamma-linolenic acid. | 1993 | Food Chem. Toxicol. | pmid:8390392 |
Oliwiecki S et al. | The effect of essential fatty acids on epidermal atrophy due to topical steroids. | 1993 | Clin. Exp. Dermatol. | pmid:8403467 |
Melnik B and Plewig G | [External treatment of atopic eczema with gamma-linolenic acid?]. | 1993 | Hautarzt | pmid:8407331 |
Beno DW et al. | Gamma-linolenic acid suppression of hepatic Ito cell mitogenesis: post-PDGF receptor prostaglandin-independent mechanism. | 1993 | Am. J. Physiol. | pmid:7694498 |
Cantrill RC et al. | Concentration-dependent effect of iron on gamma-linolenic acid toxicity in ZR-75-1 human breast tumor cells in culture. | 1993 | Cancer Lett. | pmid:8402582 |
Thurmond DC et al. | Time-dependent effects of progressive gamma-linolenate feeding on hyperphagia, weight gain, and erythrocyte fatty acid composition during growth of Zucker obese rats. | 1993 | Obes. Res. | pmid:16353349 |
Poisson JP et al. | Effect of salt-loading and spontaneous hypertension on in vitro metabolism of [1-14C]linoleic and [2-14C]dihomo-gamma-linolenic acids. | 1993 | Biochem. Med. Metab. Biol. | pmid:8382502 |
Horrobin DF | Fatty acid metabolism in health and disease: the role of delta-6-desaturase. | 1993 | Am. J. Clin. Nutr. | pmid:8386433 |
Cantrill RC et al. | The effect of n-6 fatty acids on normal and v-Ki ras transformed NIH-3T3 cells. | 1992 Nov-Dec | Anticancer Res. | pmid:1338278 |
Söreide E et al. | Long-term use of gamma-linolenic acid-enriched fat emulsion (PFE 4501): case report. | 1992 May-Jun | Nutrition | pmid:1326350 |
Takeda S et al. | Lipid peroxidation in human breast cancer cells in response to gamma-linolenic acid and iron. | 1992 Mar-Apr | Anticancer Res. | pmid:1316091 |
Dobbin SN | Evening primrose oil and epilepsy. | 1992 Dec 19-26 | Vet. Rec. | pmid:1287960 |