Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system.
To understand associated biological information of gamma-Linolenic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with gamma-Linolenic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Cameron NE and Cotter MA | Interaction between oxidative stress and gamma-linolenic acid in impaired neurovascular function of diabetic rats. | 1996 | Am. J. Physiol. | pmid:8843740 |
Williams WV et al. | Effects of unsaturated fatty acids on expression of early response genes in human T lymphocytes. | 1996 | Pathobiology | pmid:8856792 |
Deferne JL and Leeds AR | Resting blood pressure and cardiovascular reactivity to mental arithmetic in mild hypertensive males supplemented with blackcurrant seed oil. | 1996 | J Hum Hypertens | pmid:8895037 |
Papanikolaou N et al. | Effects of OKY-046 and nifedipine in cyclosporine-induced renal dysfunction in rats. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8951993 |
Matsuo N et al. | Effects of gamma-linolenic acid and its positional isomer pinolenic acid on immune parameters of brown-Norway rats. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8951990 |
Wigmore SJ et al. | The effect of polyunsaturated fatty acids on the progress of cachexia in patients with pancreatic cancer. | 1996 | Nutrition | pmid:8850216 |
Jenkins AP et al. | Essential fatty acid supplementation in chronic hepatitis B. | 1996 | Aliment. Pharmacol. Ther. | pmid:8853774 |
de Kock M et al. | The induction of apoptosis in human cervical carcinoma (HeLa) cells by gamma-linolenic acid. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:9014218 |
Hederos CA and Berg A | Epogam evening primrose oil treatment in atopic dermatitis and asthma. | 1996 | Arch. Dis. Child. | pmid:9014601 |
Ingram AJ et al. | Dietary alteration of dihomogamma-linolenic acid/arachidonic acid ratio in a rat 5/6-renal-ablation model. The Nutrition & Kidney Disease Research Group. | 1996 | J. Am. Soc. Nephrol. | pmid:8829117 |
Glen AI et al. | Membrane fatty acids, niacin flushing and clinical parameters. | 1996 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8888117 |
Cameron NE and Cotter MA | Comparison of the effects of ascorbyl gamma-linolenic acid and gamma-linolenic acid in the correction of neurovascular deficits in diabetic rats. | 1996 | Diabetologia | pmid:8877288 |
Awad AB et al. | The effect of unsaturated fatty acids on membrane composition and signal transduction in HT-29 human colon cancer cells. | 1996 | Cancer Lett. | pmid:8950205 |
Huang Z et al. | Functional identification of the active-site nucleophile of the human 85-kDa cytosolic phospholipase A2. | 1996 | Biochemistry | pmid:8619991 |
Leaver HA et al. | Arachidonic acid activation of monocyte and neutrophil reactive oxygen in lung cancer patients undergoing pulmonary resection. | 1996 | Biologicals | pmid:9088546 |
Chilton SA | Cognitive behaviour therapy for the chronic fatigue syndrome. Evening primrose oil and magnesium have been shown to be effective. | 1996 | BMJ | pmid:8616424 |
Cantrill RC et al. | Exogenous gamma-linolenic acid alters hormone stimulated cyclic AMP levels in U937 cells. | 1996 | Cancer Lett. | pmid:8620439 |
Wainwright PE et al. | Effects of dietary gamma-linolenic acid and prenatal ethanol on mouse brain and behavior. | 1996 | Pharmacol. Biochem. Behav. | pmid:8801587 |
Quoc KP and Pascaud M | Effects of dietary gamma-linolenic acid on the tissue phospholipid fatty acid composition and the synthesis of eicosanoids in rats. | 1996 | Ann. Nutr. Metab. | pmid:8773734 |
Hrelia S et al. | gamma-Linolenic acid supplementation can affect cancer cell proliferation via modification of fatty acid composition. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8753781 |
Fan YY et al. | Dietary lipid source alters murine macrophage/vascular smooth muscle cell interactions in vitro. | 1996 | J. Nutr. | pmid:8814195 |
Omawari N et al. | Deficient nitric oxide responsible for reduced nerve blood flow in diabetic rats: effects of L-NAME, L-arginine, sodium nitroprusside and evening primrose oil. | 1996 | Br. J. Pharmacol. | pmid:8733594 |
Sherrington EJ et al. | The effect of dietary lipid manipulation on the uptake of [3H]-triolein by tissues of the rat. | 1996 | Biochem. Soc. Trans. | pmid:8736833 |
Grant D et al. | The antioxidant activity of heparins. | 1996 | Biochem. Soc. Trans. | pmid:8736852 |
Stainforth JM et al. | Clinical aspects of the use of gamma linolenic acid in systemic sclerosis. | 1996 | Acta Derm. Venereol. | pmid:8740271 |
Budeiri D et al. | Is evening primrose oil of value in the treatment of premenstrual syndrome? | 1996 | Control Clin Trials | pmid:8721802 |
Chilton-Lopez ME et al. | Metabolism of gammalinolenic acid in human neutrophils. | 1996 | J. Immunol. | pmid:8609415 |
Sasaki S et al. | Effects of gamma-linolenic and eicosapentaenoic acids on blood pressure in SHR. | 1995 | Clin Exp Pharmacol Physiol Suppl | pmid:9072404 |
Luthria DL and Sprecher H | Metabolism of deuterium-labeled linoleic, 6,9,12-octadecatrienoic, 8,11,14-eicosatrienoic, and arachidonic acids in the rat. | 1995 | J. Lipid Res. | pmid:8558078 |
Berth-Jones J et al. | Evening primrose oil and atopic eczema. | 1995 | Lancet | pmid:7861894 |
Morris GM et al. | Trophic effects of essential fatty acids on pig skin. | 1995 | Cell Prolif. | pmid:7893841 |
Scholey JW and Mills DE | Dietary fatty acids and the glomerular hemodynamic response to cyclosporine in borderline hypertensive rats. | 1995 | Kidney Int. | pmid:7723248 |
Fan YY et al. | Dietary gamma-linolenic acid modulates macrophage-vascular smooth muscle cell interactions. Evidence for a macrophage-derived soluble factor that downregulates DNA synthesis in smooth muscle cells. | 1995 | Arterioscler. Thromb. Vasc. Biol. | pmid:7670954 |
Sherrington EJ et al. | The effect of dietary lipid manipulation on macrophage cell surface molecule expression. | 1995 | Biochem. Soc. Trans. | pmid:7672298 |
Karasu C et al. | Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids. | 1995 | Diabetologia | pmid:7713308 |
Dines KC et al. | Comparison of the effects of evening primrose oil and triglycerides containing gamma-linolenic acid on nerve conduction and blood flow in diabetic rats. | 1995 | J. Pharmacol. Exp. Ther. | pmid:7714803 |
Murray MJ et al. | Select dietary fatty acids attenuate cardiopulmonary dysfunction during acute lung injury in pigs. | 1995 | Am. J. Physiol. | pmid:8594921 |
Bell JG et al. | Diets rich in eicosapentaenoic acid and gamma-linolenic acid affect phospholipid fatty acid composition and production of prostaglandins E1, E2 and E3 in turbot (Scophthalmus maximus), a species deficient in delta 5 fatty acid desaturase. | 1995 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:8577782 |
Rothman D et al. | Botanical lipids: effects on inflammation, immune responses, and rheumatoid arthritis. | 1995 | Semin. Arthritis Rheum. | pmid:8578315 |
Dines CD et al. | Nerve function in galactosaemic rats: effects of evening primrose oil and doxazosin. | 1995 | Eur. J. Pharmacol. | pmid:8521914 |
Goonaratna C | Good morning, evening primrose oil. | 1995 | Ceylon Med J | pmid:8689697 |
de Bravo MG et al. | [Effect of dietary supplementation with gamma-linolenic acid on the growth of a human lung carcinoma implanted in nude mice]. | 1995 | Medicina (B Aires) | pmid:8731577 |
Giamarellos-Bourboulis EJ et al. | In-vitro inhibitory activity of gamma-linolenic acid on Escherichia coli strains and its influence on their susceptibilities to various antimicrobial agents. | 1995 | J. Antimicrob. Chemother. | pmid:8522462 |
Burgess NA et al. | Evaluation of four animal models of intrarenal calcium deposition and assessment of the influence of dietary supplementation with essential fatty acids on calcification. | 1995 | Urol. Res. | pmid:8533210 |
Harbige LS et al. | Prevention of experimental autoimmune encephalomyelitis in Lewis rats by a novel fungal source of gamma-linolenic acid. | 1995 | Br. J. Nutr. | pmid:8541276 |
Sture GH and Lloyd DH | Canine atopic disease: therapeutic use of an evening primrose oil and fish oil combination. | 1995 | Vet. Rec. | pmid:8553525 |
Cartwright-Shamoon JM et al. | A complex biochemical modulation of intestinal ion transport in rats fed on high-fat diets. | 1995 | J. Pediatr. Gastroenterol. Nutr. | pmid:7884616 |
Karikó K et al. | Stimulatory effect of unsaturated fatty acids on the level of plasminogen activator inhibitor-1 mRNA in cultured human endothelial cells. | 1995 | FEBS Lett. | pmid:7890029 |
Lindskov R and Petersen CS | [Oral gamma-linoleic acid (Epogam) in the treatment of atopic dermatitis]. | 1995 | Ugeskr. Laeg. | pmid:7483071 |
Jiang WG et al. | Regulation of the expression of E-cadherin on human cancer cells by gamma-linolenic acid (GLA). | 1995 | Cancer Res. | pmid:7585549 |